Naglazyme and dyspnoea Patient Reports February 11, 2012

Naglazyme Side Effects Report #5466035-5
Naglazyme side effect was reported by a Physician from BRAZIL on Sept 04, 2007. Female patient, child 8 years of age, weighting 28.66 lb, was diagnosed with mucopolysaccharidosis vi and was treated with Naglazyme. After drug was administered, patient experienced the following side effects: abdominal pain , apnoea, bradycardia, choking , dyspnoea, pyrexia. Naglazyme dosage: 1 MG/KG; QW; IV. During the same period patient was treated with BENADRYL. Patient recovered.

Naglazyme Side Effects Report #5565056-1
Naglazyme side effect was reported by a Physician from BRAZIL on Nov 27, 2007. Female patient, child 8 years of age, weighting 72.75 lb, was diagnosed with mucopolysaccharidosis vi and was treated with Naglazyme. After drug was administered, patient experienced the following side effects: abdominal pain , apnoea, bradycardia, choking , dyspnoea, hyperthermia, hypothermia . Naglazyme dosage: 1 MG/KG;QW;IV. During the same period patient was treated with BENADRYL. Patient recovered.

Naglazyme Side Effects Report #5946393-5
Naglazyme side effect was reported by a Consumer or non-health professional from UNITED STATES on Sept 04, 2008. Female patient, 28 years of age, weighting 68.34 lb, was diagnosed with mucopolysaccharidosis vi and was treated with Naglazyme. After drug was administered, patient experienced the following side effects: acute pulmonary oedema, cardiac failure congestive, chest pain , dyspnoea, international normalised ratio abnormal, pneumonia , sepsis . Naglazyme dosage: 22 MG;QW;IVDRP. Patient was hospitalized. Patient died on 08/30/2008.

Naglazyme Side Effects Report #5614707-1
Naglazyme side effect was reported by a Physician from PORTUGAL on Jan 16, 2008. Male patient, 14 years of age, weighting 94.80 lb, was diagnosed with mucopolysaccharidosis vi and was treated with Naglazyme. After drug was administered, patient experienced the following side effects: blood pressure increased, body temperature increased, cyanosis, dyspnoea, haemorrhage, infusion related reaction, oxygen saturation decreased, pharyngeal oedema, rash . Naglazyme dosage: QW IV ; 43 MG 1X IV. Patient recovered.


Naglazyme Side Effects Report #5682171-2
Naglazyme side effect was reported by a Physician from PORTUGAL on Mar 10, 2008. Male patient, 14 years of age, weighting 94.80 lb, was diagnosed with mucopolysaccharidosis vi and was treated with Naglazyme. After drug was administered, patient experienced the following side effects: blood pressure increased, body temperature increased, cyanosis, dyspnoea, oxygen saturation decreased, rash , tachycardia, tremor. Naglazyme dosage: QW;IV; 43 MG;QW;IV. During the same period patient was treated with CLEMASTINE FUMARATE. Patient recovered.

Naglazyme Side Effects Report #5724467-1
Naglazyme side effect was reported by a Consumer or non-health professional from AUSTRALIA on Apr 14, 2008. Female patient, 14 years of age, weighting 35.27 lb, was diagnosed with mucopolysaccharidosis vi and was treated with Naglazyme. After drug was administered, patient experienced the following side effects: blood pressure decreased, chills, dizziness , dyspnoea, emotional distress, infusion related reaction, irritability, livedo reticularis. Naglazyme dosage: 20 MG;QW;IV. During the same period patient was treated with MONTELUKAST, FLUTICASONE, ALBUTEROL, BUDESONIDE, ROXITHROMYCIN, AUGMENTIN, PREDNISOLONE, CIPROFLOXACIN. Patient was hospitalized. Patient recovered.