Naglazyme and cardiac arrest Patient Reports February 11, 2012

Naglazyme Side Effects Report #5828150-3
Naglazyme side effect was reported by a Physician from BRAZIL on July 14, 2008. Male patient, child 9 years of age, weighting 39.68 lb, was diagnosed with mucopolysaccharidosis vi and was treated with Naglazyme. After drug was administered, patient experienced the following side effects: cardiac arrest , poor venous access, pyrexia. Naglazyme dosage: 1 MG/KG; QW; IV. Patient died on 06/27/2008.

Naglazyme Side Effects Report #5982111-2
Naglazyme side effect was reported by a Physician from TURKEY on Nov 17, 2008. Male patient, child 7 years of age, weighting 37.48 lb, was diagnosed with mucopolysaccharidosis vi and was treated with Naglazyme. After drug was administered, patient experienced the following side effects: anxiety , cardiac arrest , syncope. Naglazyme dosage: 15 MG;QW; IVDRP. Patient died on 10/27/2008.

Naglazyme Side Effects Report #5629947-5
Naglazyme side effect was reported by a Health Professional from IRELAND on Jan 28, 2008. Female patient, 13 years of age, was diagnosed with mucopolysaccharidosis vi and was treated with Naglazyme. After drug was administered, patient experienced the following side effects: cardiac arrest , pneumonia , pulmonary hypertension . Naglazyme dosage: unknown. Patient was hospitalized. Patient died on 01/01/2008.

Naglazyme Side Effects Report #5646419-2
Naglazyme side effect was reported by a Physician from IRELAND on Feb 13, 2008. Female patient, child 11 years of age, weighting 44.09 lb, was diagnosed with mucopolysaccharidosis vi and was treated with Naglazyme. After drug was administered, patient experienced the following side effects: aortic valve incompetence, cardiac arrest , mitral valve incompetence, pneumonia , pulmonary haemorrhage, pulmonary hypertension , respiratory tract infection, tricuspid valve incompetence. Naglazyme dosage: 20 MG QW IV. During the same period patient was treated with MEROPENEM, VANCOMYCIN, ERYTHROMYCIN, CIPROFLOXACIN, VORICONAZOLE, MILRINONE LACTATE, FUROSEMIDE, MORPHINE. Patient was hospitalized. Patient died on 01/25/2008.


Naglazyme Side Effects Report #5673975-0
Naglazyme side effect was reported by a Consumer or non-health professional from IRELAND on Feb 29, 2008. Female patient, child 11 years of age, weighting 44.09 lb, was diagnosed with mucopolysaccharidosis vi and was treated with Naglazyme. After drug was administered, patient experienced the following side effects: abdominal pain upper, aortic valve incompetence, back pain , blood pressure decreased, cardiac arrest , diarrhoea, headache , hepatomegaly. Naglazyme dosage: 20 MG; QW; IV. During the same period patient was treated with MEROPENEM, VANCOMYCIN, ERYTHROMYCIN, CIPROFLOXACIN, VORICONAZOLE, MILRINONE LACTATE, FUROSEMIDE, MORPHINE. Patient was hospitalized. Patient died on 01/25/2008.

Naglazyme Side Effects Report #6006172-X
Naglazyme side effect was reported by a Physician from TURKEY on Nov 28, 2008. Male patient, child 7 years of age, weighting 37.48 lb, was diagnosed with mucopolysaccharidosis iv and was treated with Naglazyme. After drug was administered, patient experienced the following side effects: anxiety , cardiac arrest , tachycardia. Naglazyme dosage: 15 MG;QW;IVDRP. Patient died on 10/27/2008.