Myozyme and respiratory distress 
Myozyme and respiratory distress Patient Reports February 12, 2012
Myozyme Side Effects Report #5753661-9
Myozyme side effect was reported by a Physician from UNITED STATES on May 14, 2008. Female patient, 66 years of age, weighting 191.8 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood pressure decreased, feeling hot, hypersensitivity, oxygen saturation decreased, respiratory distress. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. Patient recovered.
Myozyme Side Effects Report #5753664-4
Myozyme side effect was reported by a Physician from UNITED STATES on May 14, 2008. Female patient, 66 years of age, weighting 191.8 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood pressure decreased, feeling hot, hypersensitivity, oxygen saturation decreased, respiratory distress. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. Patient recovered.
Myozyme Side Effects Report #5248067-5
Myozyme side effect was reported by a Physician from GERMANY on Feb 08, 2007. Female patient, 55 years of age, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: bronchospasm, chest discomfort, dyspnoea, infusion related reaction, oxygen saturation decreased, respiratory distress. Myozyme dosage: 1200 MG Q2WKS IV. Patient recovered.
Myozyme Side Effects Report #5170229-6
Myozyme side effect was reported by a Physician from GERMANY on Nov 21, 2006. Female patient, 55 years of age, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: chest discomfort, infusion related reaction, oxygen saturation decreased, respiratory distress. Myozyme dosage: 1200 MG Q2WKS IV. Patient recovered.
Myozyme Side Effects Report #5585848-2
Myozyme side effect was reported by a Physician from ARGENTINA on Dec 21, 2007. Female patient, child 3 years of age, weighting 35.27 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: atelectasis, bronchospasm, device failure, pneumonia
, respiratory distress. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. During the same period patient was treated with FLUTICASONE PROPIONATE, FERROUS SULPHATE, SALBUTAMOL, CARNITENE. Patient was hospitalized. Patient recovered.Myozyme Side Effects Report #5625286-7
Myozyme side effect was reported by a Physician from ARGENTINA on Jan 30, 2008. Female patient, child 3 years of age, weighting 35.27 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: atelectasis, bronchospasm, device failure, infusion related reaction, oxygen saturation decreased, pneumonia
, pyrexia, respiratory distress. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. During the same period patient was treated with FLUTICASONE PROPIONATE, FEROUS SULPHATE, SALBUTAMOL, CARNITENE. Patient was hospitalized. Patient recovered.Myozyme Side Effects Report #6046002-3
Myozyme side effect was reported by a Physician from UNITED STATES on Jan 09, 2009. Female patient, child 3 years of age, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: alopecia, cardiomyopathy
, dehydration, disease progression, foreign body trauma, infection , pneumonia , respiratory distress, respiratory failure. Myozyme dosage: 300 MG, Q2W, INTRAVENOUS. Patient recovered.Myozyme Side Effects Report #6028061-7
Myozyme side effect was reported by a Health Professional from UNITED STATES on Dec 17, 2008. Male patient, child 2 years of age, weighting 28.66 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: catheter related infection, gastroenteritis viral, moraxella infection, neutrophil count decreased, pseudomonas infection, respiratory distress, retching, salivary hypersecretion, tracheobronchitis. Myozyme dosage: 40 MG/KG, Q2W, INTRAVENOUS; 30 MG/KG, Q2W, INTRAVENOUS; 20 MG/KG, Q2W, INTRAVENOUS. During the same period patient was treated with BENADRYL, ACETAMINOPHEN, HYDROCORTISONE, CALCIUM GLUCONATE, EPOGEN. Patient was hospitalized. Patient recovered.
Myozyme Side Effects Report #5425042-9
Myozyme side effect was reported by a Consumer or non-health professional from UNITED STATES on Apr 03, 2007. Male patient, child 1 years of age, weighting 28.66 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: pneumonia
, respiratory distress, respiratory failure. Myozyme dosage: unknown. During the same period patient was treated with ALPHA. Patient was hospitalized. Patient recovered.Myozyme Side Effects Report #5218783-X
Myozyme side effect was reported by a Health Professional from UNITED STATES on Jan 09, 2007. Male patient, weighting 11.05 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: glycogen storage disease type ii, hypotonia, muscular weakness, oral intake reduced, pneumonia
, respiratory distress, sleep apnoea syndrome, stomatitis. Myozyme dosage: 130 MG Q2WKS IV. During the same period patient was treated with ALBUTEROL, PROPRANOLOL, ZANTAC. Patient was hospitalized. Patient recovered.Myozyme Side Effects Report #5229469-X
Myozyme side effect was reported by a Physician from UNITED STATES on Jan 17, 2007. Male patient, weighting 15.21 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood pressure systolic increased, cardiac arrest
, infection , pyrexia, respiratory distress, tachycardia, wheezing. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with DIPHENHYDRAMINE, ACETAMINOPHEN, POTASSIUM CHLORIDE, FAMOTIDINE, DIGOXIN, PROPRANOLOL, FUROSEMIDE, HYDROCHLOROTHIAZIDE. Patient recovered.Myozyme Side Effects Report #5236946-4
Myozyme side effect was reported by a Physician from UNITED STATES on Jan 26, 2007. Male patient, weighting 11.05 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: carbon dioxide increased, cardiomegaly, muscular weakness, pneumonia
, respiratory distress, sleep apnoea syndrome. Myozyme dosage: 130 MG Q2WKS IV. During the same period patient was treated with ALBUTEROL, PROPRANOLOL, ZANTAC. Patient was hospitalized. Patient recovered.Myozyme Side Effects Report #5236957-9
Myozyme side effect was reported by a Physician from UNITED STATES on Jan 26, 2007. Female patient, weighting 26.01 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: cardiac failure, international normalised ratio increased, prothrombin time prolonged, respiratory distress, shock, urine output decreased, urticaria. Myozyme dosage: 250 MG Q2WKS IV. During the same period patient was treated with PULMICORT, CAPTOPRIL, CARVEDILOL, DIGOXIN, LASIX. Patient was hospitalized. Patient died on 02/03/2007.
Myozyme Side Effects Report #5245892-1
Myozyme side effect was reported by a Physician from UNITED STATES on Feb 01, 2007. Male patient, weighting 15.21 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood magnesium increased, blood pressure decreased, cardio-respiratory arrest, heart rate decreased, hypersensitivity, infection
, infusion related reaction, respiratory distress, respiratory rate increased. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with DIPHENHYDRAMINE, ACETAMINOPHEN, POTASSIUM CHLORIDE, FAMOTIDINE, DIGOXIN, PROPRANOLOL, FUROSEMIDE, HYDROCHLOROTHIAZIDE. Patient recovered.Myozyme Side Effects Report #5299727-1
Myozyme side effect was reported by a Physician from ARGENTINA on Mar 27, 2007. Female patient was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: cardiac failure, culture positive, pneumonia
, pseudomonas infection, respiratory distress, sepsis . Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with MEROPENIN, FUROSEMIDE, AMIKACIN, DOPAMINE, MILRINONE, POTASSIUM CHLORIDE, CALCIUM CHLORIDE. Patient was hospitalized. Patient died on 03/28/2007.Myozyme Side Effects Report #5306939-7
Myozyme side effect was reported by a Physician from UNITED STATES on Apr 05, 2007. Male patient was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: respiratory distress, tracheitis. Myozyme dosage: 130 MG Q2WKS IV. Patient was hospitalized. Patient recovered.
Myozyme Side Effects Report #5091563-4
Myozyme side effect was reported by a Physician from UNITED STATES on July 06, 2006. Female patient, weighting 20.94 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: cardiac failure congestive, hypoxia, ileus, pyrexia, respiratory distress, retching, vomiting. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with ALPHA, DIGOXIN, LASIX, ENALAPRIL, PRILOSEC, METOCLOPRAMIDE. Patient was hospitalized. Patient recovered.
Myozyme Side Effects Report #5192519-3
Myozyme side effect was reported by a Physician from SAUDI ARABIA on Dec 05, 2006. Male patient, weighting 12.79 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: disease progression, respiratory distress, sepsis
. Myozyme dosage: unknown. During the same period patient was treated with ANTIBIOTIC, ANTIFUNGAL. Patient died on 07/21/2006.Myozyme Side Effects Report #5404196-4
Myozyme side effect was reported by a Physician from UNITED STATES on July 17, 2007. Male patient was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood gases abnormal, cardio-respiratory arrest, oxygen saturation decreased, pneumonia aspiration, respiratory distress, respiratory failure. Myozyme dosage: 20 MG/KG Q2WKS IV. Patient was hospitalized. Patient died on 07/19/2007.
Myozyme Side Effects Report #5425044-2
Myozyme side effect was reported by a Consumer or non-health professional from UNITED STATES on Apr 17, 2007. Female patient was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: pyrexia, respiratory distress. Myozyme dosage: 20 MG, KG, Q2WKS; IV. Patient was hospitalized. Patient recovered.
Myozyme Side Effects Report #5425045-4
Myozyme side effect was reported by a Physician from UNITED STATES on Apr 04, 2007. Female patient, weighting 13.23 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: pyrexia, respiratory distress. Myozyme dosage: 20 MG, KG, Q2WKS; IV. Patient was hospitalized. Patient recovered.
Myozyme Side Effects Report #5586084-6
Myozyme side effect was reported by a Health Professional from UNITED STATES on Dec 27, 2007. Female patient was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: bradycardia, cardiac arrest
, catheter related infection, hypoxic encephalopathy, influenza, infusion related reaction, respiratory distress, respiratory failure, sepsis . Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. Patient was hospitalized. Patient died on 12/21/2007.Myozyme Side Effects Report #5805198-6
Myozyme side effect was reported by a Physician from UNITED STATES on June 27, 2008. Male patient, weighting 14.77 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: cardiomegaly, dysphagia, hypotonia, influenza, otitis media, pneumonia aspiration, respiratory distress, respiratory syncytial virus infection
. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. During the same period patient was treated with SYNAGIS. Patient was hospitalized. Patient recovered.Myozyme Side Effects Report #5839280-4
Myozyme side effect was reported by a Physician from FRANCE on July 22, 2008. Female patient was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, hypertension, pyrexia, respiratory failure. Myozyme dosage: 150 MG, Q4W, INTRAVENOUS, 100 MG, Q4W, INTRAVENOUS. Patient was hospitalized. Patient died on 07/25/2008.
Myozyme Side Effects Report #5842959-1
Myozyme side effect was reported by a Physician from KUWAIT on July 23, 2008. Male patient, weighting 12.13 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: body temperature increased, cardio-respiratory arrest, coma, movement disorder
, pneumonia , respiratory distress, tachypnoea, wheezing. Myozyme dosage: 100 MG, Q2W, INTRAVENOUS. During the same period patient was treated with VENTOLIN, LASIX, ALDACTONE, CAPTOPRIL, DOPAMINE. Patient was hospitalized. Patient died on 07/18/2008.Myozyme Side Effects Report #5849977-8
Myozyme side effect was reported by a Physician from UNITED STATES on Aug 04, 2008. Male patient, weighting 20.06 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: hyperhidrosis, infusion related reaction, oxygen saturation decreased, pallor, petechiae, rash
, respiratory distress, retching, tachycardia. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. During the same period patient was treated with RANITIDINE, PREDNISONE, CETIRIZINE, XOPENEX, PULMICORT, IPRATROPIUM BR, METOCLORPAMIDE, FLUCONAZOLE. Patient was hospitalized. Patient recovered.Myozyme Side Effects Report #5850383-0
Myozyme side effect was reported by a Physician from UNITED STATES on Aug 01, 2008. Male patient, weighting 20.06 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: grunting, hyperhidrosis, infusion related reaction, oxygen saturation decreased, pallor, petechiae, rash
, respiratory distress, retching. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. During the same period patient was treated with RANITIDINE, PREDNISONE, CETIRIZINE, XOPENEX, PULMICORT, IPRATROPIUM BR, METOCLOPRAMIDE, FLUCONAZOLE. Patient was hospitalized. Patient recovered.Myozyme Side Effects Report #5851864-6
Myozyme side effect was reported by a Physician from FRANCE on Aug 05, 2008. Female patient was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, hypertension, pyrexia, respiratory failure. Myozyme dosage: 150 MG, Q4W, INTRAVENOUS; 100 MG Q4W INTRAVENOUS. During the same period patient was treated with FUROSEMIDE. Patient was hospitalized. Patient died on 07/25/2008.
Myozyme Side Effects Report #5930832-X
Myozyme side effect was reported by a Physician from KUWAIT on Oct 16, 2008. Male patient, weighting 12.13 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: cardio-respiratory arrest, coma, hypotension, pneumonia
, pyrexia, respiratory distress, tachycardia, wheezing. Myozyme dosage: 100 MG, Q2W, INTRAVENOUS. During the same period patient was treated with VENTOLIN, LASIX, ALDACTONE, CAPTOPRIL, DOPAMINE. Patient was hospitalized and became disabled. Patient died on 07/18/2008.Myozyme Side Effects Report #6060120-5
Myozyme side effect was reported by a Physician from UNITED ARAB EMIRATES on Jan 15, 2009. Male patient was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: aspartate aminotransferase increased, blood creatine phosphokinase increased, blood lactate dehydrogenase increased, cardiac failure, hypotension, respiratory distress. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. Patient was hospitalized. Patient recovered.