Myozyme and pyrexia Patient Reports February 12, 2012

Myozyme Side Effects Report #5832466-4
Myozyme side effect was reported by a Consumer or non-health professional from NETHERLANDS on July 16, 2008. Male patient, child 4 years of age, weighting 36.82 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: lung infection, pyrexia, quadriplegia, respiratory disorder. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. Patient died on 04/26/2008.

Myozyme Side Effects Report #5897263-2
Myozyme side effect was reported by a Physician from AUSTRALIA on Sept 10, 2008. Female patient, child 4 years of age, weighting 38.14 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood pressure diastolic increased, pyrexia, supraventricular tachycardia. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS; 40 MG/KG, Q2W. During the same period patient was treated with KEPPRA. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #5931798-9
Myozyme side effect was reported by a Physician from AUSTRALIA on Oct 08, 2008. Female patient, child 4 years of age, weighting 38.14 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood pressure fluctuation, pyrexia, respiratory rate increased, supraventricular tachycardia. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS; 40 MG/KG, Q2W. During the same period patient was treated with KEPPRA. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #5692867-4
Myozyme side effect was reported by a Physician from ITALY on Mar 19, 2008. Male patient, 39 years of age, weighting 94.80 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: cardiac failure, haemothorax, pneumothorax, pyrexia, respiratory failure, sepsis . Myozyme dosage: 20 MG/KG, INTRAVENOUS. During the same period patient was treated with ANTIBIOTICS. Patient died on 12/06/2007.


Myozyme Side Effects Report #5625286-7
Myozyme side effect was reported by a Physician from ARGENTINA on Jan 30, 2008. Female patient, child 3 years of age, weighting 35.27 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: atelectasis, bronchospasm, device failure, infusion related reaction, oxygen saturation decreased, pneumonia , pyrexia, respiratory distress. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. During the same period patient was treated with FLUTICASONE PROPIONATE, FEROUS SULPHATE, SALBUTAMOL, CARNITENE. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #5807094-7
Myozyme side effect was reported by a Physician from UNITED KINGDOM on June 24, 2008. Male patient, child 3 years of age, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: aspiration, fatigue, pyrexia. Myozyme dosage: 20 MG, Q2W, INTRAVENOUS. Patient recovered.

Myozyme Side Effects Report #5995082-X
Myozyme side effect was reported by a Physician from BRAZIL on Dec 03, 2008. Female patient, child 3 years of age, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: cardiac failure, choking , cough, hypotension, influenza, infusion related reaction, pyrexia, viral infection . Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #5362829-5
Myozyme side effect was reported by a Physician from UNITED STATES on June 03, 2007. Male patient, 22 years of age, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: arthralgia, condition aggravated, oedema peripheral, pain in extremity, pyrexia. Myozyme dosage: 20 MG/KG Q2WKS IV. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #5328162-2
Myozyme side effect was reported by a Physician from ARGENTINA on Apr 30, 2007. Male patient, child 2 years of age, weighting 30.86 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: atelectasis, device migration, hypoxia, pyrexia, tracheal disorder. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with ALPHA, FLUTICASONE PROPIONATE, ALBUTEROL. Patient was hospitalized. Patient recovered.


Myozyme Side Effects Report #5339036-5
Myozyme side effect was reported by a Physician from ARGENTINA on May 11, 2007. Male patient, child 2 years of age, weighting 32.23 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: dyspnoea, pyrexia. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with ALPHA, FLUTICASONE PROPIONATE, SALBUTAMOL. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #5679716-5
Myozyme side effect was reported by a Physician from BRAZIL on Mar 10, 2008. Female patient, child 2 years of age, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: productive cough, pyrexia, viral infection . Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #6112213-1
Myozyme side effect was reported by a Health Professional from UNITED STATES on Feb 26, 2009. Male patient, child 2 years of age, weighting 28.66 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: central line infection, diarrhoea, gastroenteritis viral, nausea , pyrexia, retching, salivary hypersecretion, staphylococcal infection , tracheobronchitis. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS; 30 MG/KG, Q2W, INTRAVENOUS; 40 MG/KG, Q2W, INTRAVENOUS. During the same period patient was treated with BENADRYL, ACETAMINOPHEN. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #5757711-5
Myozyme side effect was reported by a Physician from COLOMBIA on May 19, 2008. Male patient, 13 years of age, weighting 99.21 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: dyspnoea, pleural effusion, pneumonia , productive cough, pyrexia. Myozyme dosage: 19 MG/KG, QOW, INTRAVENOUS. During the same period patient was treated with THEOPHYLLINE, FLUOXETINE, SALBUTAMOL. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #5676851-2
Myozyme side effect was reported by a Physician from CANADA on Mar 05, 2008. Male patient, child 10 years of age, weighting 62.83 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: cardiac arrest , osteonecrosis , post procedural complication, pyrexia, tooth extraction. Myozyme dosage: 20 MG/KG, Q2W. Patient was hospitalized. Patient recovered.


Myozyme Side Effects Report #5327219-X
Myozyme side effect was reported by a Physician from UNITED STATES on May 02, 2007. Female patient, child 1 years of age, weighting 20.94 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: antibody test positive, disease progression, enzyme inhibition, muscle disorder , pyrexia. Myozyme dosage: 20 MG;KG Q2WKS IV. During the same period patient was treated with ALPHA. Patient recovered.

Myozyme Side Effects Report #5945734-2
Myozyme side effect was reported by a Physician from UNITED KINGDOM on Oct 22, 2008. Male patient, child 1 years of age, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: hypokinesia, muscular weakness, pyrexia, social avoidant behaviour. Myozyme dosage: unknown. Patient recovered.

Myozyme Side Effects Report #5229469-X
Myozyme side effect was reported by a Physician from UNITED STATES on Jan 17, 2007. Male patient, weighting 15.21 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood pressure systolic increased, cardiac arrest , infection , pyrexia, respiratory distress, tachycardia, wheezing. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with DIPHENHYDRAMINE, ACETAMINOPHEN, POTASSIUM CHLORIDE, FAMOTIDINE, DIGOXIN, PROPRANOLOL, FUROSEMIDE, HYDROCHLOROTHIAZIDE. Patient recovered.

Myozyme Side Effects Report #5254712-0
Myozyme side effect was reported by a Physician from UNITED STATES on Feb 12, 2007. Male patient, weighting 15.21 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood magnesium increased, blood pressure decreased, cardio-respiratory arrest, cough, crying, hypersensitivity, infection , pyrexia, respiratory distress. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with DIPHENHYDRAMINE, ACETAMINOPHEN, POTASSIUM CHLORIDE, FAMOTIDINE, DIGOXIN, PROPRANOLOL, FUROSEMIDE. Patient recovered.

Myozyme Side Effects Report #5268621-4
Myozyme side effect was reported by a Physician from BRAZIL on Feb 28, 2007. Female patient, weighting 16.31 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: bradycardia, brain oedema, cardiogenic shock, cardiomyopathy , cyanosis, disease progression, pyrexia, tachycardia. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with CARVEDILOL, CAPTOPRIL. Patient died on 02/13/2007.


Myozyme Side Effects Report #5362841-6
Myozyme side effect was reported by a Physician from UNITED STATES on June 01, 2007. Male patient was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: base excess increased, blood bicarbonate increased, muscle disorder , oxygen saturation decreased, pyrexia, respiratory failure, wheezing. Myozyme dosage: 10 MG/KG QWK IV. During the same period patient was treated with DIGOXIN. Patient died on 06/07/2007.

Myozyme Side Effects Report #5376544-5
Myozyme side effect was reported by a Physician from ISRAEL on June 17, 2007. Male patient, weighting 11.02 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: cardiopulmonary failure, cough, hypertrophic cardiomyopathy, pyrexia. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with PROPRANOLOL, CAPTOPRIL. Patient was hospitalized. Patient died on 06/10/2007.

Myozyme Side Effects Report #5091563-4
Myozyme side effect was reported by a Physician from UNITED STATES on July 06, 2006. Female patient, weighting 20.94 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: cardiac failure congestive, hypoxia, ileus, pyrexia, respiratory distress, retching, vomiting. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with ALPHA, DIGOXIN, LASIX, ENALAPRIL, PRILOSEC, METOCLOPRAMIDE. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #5100817-4
Myozyme side effect was reported by a Health Professional from BRAZIL on Aug 23, 2006. Female patient, weighting 16.87 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: infusion related reaction, pallor, pulse absent, pyrexia, tremor. Myozyme dosage: 20 MG/KG Q2WKS IV. Patient recovered.

Myozyme Side Effects Report #5110813-9
Myozyme side effect was reported by a Physician from BRAZIL on Sept 07, 2006. Female patient, weighting 16.87 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: complement factor increased, pallor, pulse absent, pyrexia, tremor. Myozyme dosage: 20 MG/KG Q2WKS. Patient recovered.


Myozyme Side Effects Report #5205595-6
Myozyme side effect was reported by a Pharmacist from UNITED STATES on July 31, 2006. Male patient, weighting 16.76 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: heart rate increased, pyrexia, tremor. Myozyme dosage: 20 MG/KG Q2WKS; IV. During the same period patient was treated with BENADRYL, TYLENOL. Patient recovered.

Myozyme Side Effects Report #5154619-3
Myozyme side effect was reported by a Physician from GREECE on Oct 30, 2006. Female patient was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: cardiac function test abnormal, cardiac ventricular disorder, diarrhoea, pyrexia, weight decreased. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with CARDIAC SUPPORTIVE TREATMENT. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #5425044-2
Myozyme side effect was reported by a Consumer or non-health professional from UNITED STATES on Apr 17, 2007. Female patient was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: pyrexia, respiratory distress. Myozyme dosage: 20 MG, KG, Q2WKS; IV. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #5425045-4
Myozyme side effect was reported by a Physician from UNITED STATES on Apr 04, 2007. Female patient, weighting 13.23 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: pyrexia, respiratory distress. Myozyme dosage: 20 MG, KG, Q2WKS; IV. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #5480985-5
Myozyme side effect was reported by a Physician from BELGIUM on Sept 20, 2007. Female patient was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: pyrexia, respiratory disorder. Myozyme dosage: 20 MG Q2WKS IV. Patient was hospitalized. Patient recovered.


Myozyme Side Effects Report #5550504-3
Myozyme side effect was reported by a Physician from BELGIUM on Nov 21, 2007. Female patient was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: infusion related reaction, pyrexia, respiratory disorder. Myozyme dosage: unknown. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #5587783-2
Myozyme side effect was reported by a Physician from UNITED STATES on Dec 27, 2007. Female patient, weighting 7.72 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: bradycardia, cardiac arrest , hypoperfusion, pyrexia. Myozyme dosage: 20 MG/KG, ONCE, INTRAVENOUS. During the same period patient was treated with MILRINONE, FENTANYL, DOPAMINE, ESMOLOL, EPINEPHRINE, PANCURONIUM, FUROSEMIDE, VANCOMYCIN. Patient was hospitalized. Patient died on 12/16/2007.

Myozyme Side Effects Report #5637776-1
Myozyme side effect was reported by a Health Professional from UNITED STATES on Feb 07, 2008. Female patient, weighting 20.94 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: disease progression, glycogen storage disease type ii, muscular weakness, pyrexia. Myozyme dosage: 20 MG/KG, Q2W,INTRAVENOUS. Patient died on 08/30/2007.

Myozyme Side Effects Report #5659994-9
Myozyme side effect was reported by a Health Professional from UNITED STATES on Mar 03, 2008. Female patient, weighting 20.94 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: cardiopulmonary failure, disease progression, muscular weakness, no therapeutic response, pyrexia, refusal of treatment by relative. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. Patient died on 08/30/2007.

Myozyme Side Effects Report #5839280-4
Myozyme side effect was reported by a Physician from FRANCE on July 22, 2008. Female patient was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, hypertension, pyrexia, respiratory failure. Myozyme dosage: 150 MG, Q4W, INTRAVENOUS, 100 MG, Q4W, INTRAVENOUS. Patient was hospitalized. Patient died on 07/25/2008.


Myozyme Side Effects Report #5850894-8
Myozyme side effect was reported by a Physician from UNITED KINGDOM on Aug 04, 2008. Male patient was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: cardiac arrest , cardiopulmonary failure, pyrexia, sepsis . Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. Patient was hospitalized. Patient died.

Myozyme Side Effects Report #5851864-6
Myozyme side effect was reported by a Physician from FRANCE on Aug 05, 2008. Female patient was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, hypertension, pyrexia, respiratory failure. Myozyme dosage: 150 MG, Q4W, INTRAVENOUS; 100 MG Q4W INTRAVENOUS. During the same period patient was treated with FUROSEMIDE. Patient was hospitalized. Patient died on 07/25/2008.

Myozyme Side Effects Report #5895396-8
Myozyme side effect was reported by a Physician from TAIWAN, PROVINCE OF CHINA on Sept 10, 2008. Male patient was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: cough, decreased appetite, dehydration, gastroenteritis , pyrexia, rhinorrhoea, vomiting. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. During the same period patient was treated with BIOFERMIN. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #5930832-X
Myozyme side effect was reported by a Physician from KUWAIT on Oct 16, 2008. Male patient, weighting 12.13 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: cardio-respiratory arrest, coma, hypotension, pneumonia , pyrexia, respiratory distress, tachycardia, wheezing. Myozyme dosage: 100 MG, Q2W, INTRAVENOUS. During the same period patient was treated with VENTOLIN, LASIX, ALDACTONE, CAPTOPRIL, DOPAMINE. Patient was hospitalized and became disabled. Patient died on 07/18/2008.

Myozyme Side Effects Report #5955955-0
Myozyme side effect was reported by a Health Professional from UNITED STATES on Oct 29, 2008. Female patient, weighting 20.06 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: apnoea, cardio-respiratory arrest, influenza, infusion related reaction, left ventricular hypertrophy, loss of consciousness, pneumonia aspiration, pyrexia. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. During the same period patient was treated with ZANTAC, FLOVENT. Patient was hospitalized. Patient recovered.


Myozyme Side Effects Report #5963759-8
Myozyme side effect was reported by a Physician from UNITED KINGDOM on Nov 14, 2008. Male patient was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: hypokinesia, muscular weakness, pyrexia, social avoidant behaviour. Myozyme dosage: 20 MG/KG Q2W INTRAVENOUS. Patient recovered.

Myozyme Side Effects Report #5989754-0
Myozyme side effect was reported by a Physician from UNITED KINGDOM on Dec 02, 2008. Male patient was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood immunoglobulin g increased, cytomegalovirus infection , hypokinesia, muscular weakness, pyrexia, social avoidant behaviour. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. Patient recovered.

Myozyme Side Effects Report #6130555-0
Myozyme side effect was reported by a Health Professional from UNITED STATES on Mar 09, 2009. Female patient, weighting 16.76 lb, was diagnosed with cardiomyopathy  and was treated with Myozyme. After drug was administered, patient experienced the following side effects: cardiomyopathy , pyrexia, respiratory failure. Myozyme dosage: 150 MG, QW, INTRAVENOUS. During the same period patient was treated with MILRINONE. Patient was hospitalized. Patient recovered.