Myozyme and hypersensitivity Patient Reports February 13, 2012

Myozyme Side Effects Report #5677967-7
Myozyme side effect was reported by a Health Professional from UNITED STATES on Mar 05, 2008. Female patient, child 9 years of age, weighting 66.14 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: anxiety , chest discomfort, cyanosis, dyspnoea, eye swelling, flushing, hypersensitivity, nausea , pallor. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. During the same period patient was treated with FLONASE, CONCERTA, ALBUTEROL. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #5753661-9
Myozyme side effect was reported by a Physician from UNITED STATES on May 14, 2008. Female patient, 66 years of age, weighting 191.8 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood pressure decreased, feeling hot, hypersensitivity, oxygen saturation decreased, respiratory distress. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. Patient recovered.

Myozyme Side Effects Report #5753664-4
Myozyme side effect was reported by a Physician from UNITED STATES on May 14, 2008. Female patient, 66 years of age, weighting 191.8 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood pressure decreased, feeling hot, hypersensitivity, oxygen saturation decreased, respiratory distress. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. Patient recovered.

Myozyme Side Effects Report #5752263-8
Myozyme side effect was reported by a Physician from UNITED STATES on May 14, 2008. Female patient, 61 years of age, weighting 121.3 lb, was diagnosed with glycogen storage disease type ii, infusion related reaction and was treated with Myozyme. After drug was administered, patient experienced the following side effects: abdominal pain , bradycardia, chills, hypersensitivity, hypotension, hypothermia , infusion related reaction, myocardial infarction. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. During the same period patient was treated with EPINEPHRINE, EVISTA, CALTRATE, ALPHAGAN, CENTRUM, ADVIL. Patient was hospitalized. Patient recovered.


Myozyme Side Effects Report #5766642-6
Myozyme side effect was reported by a Physician from UNITED STATES on May 27, 2008. Female patient, 61 years of age, weighting 121.3 lb, was diagnosed with glycogen storage disease type ii, infusion related reaction and was treated with Myozyme. After drug was administered, patient experienced the following side effects: abdominal pain , bradycardia, chills, hypersensitivity, hypotension, hypothermia , myocardial infarction, pallor. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. During the same period patient was treated with EPINEPHRINE, EVISTA, CALTRATE, ALPHAGAN, CENTRUM, ADVIL. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #5853417-2
Myozyme side effect was reported by a Physician from ISRAEL on Aug 06, 2008. Female patient, child 6 years of age, weighting 44.09 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: activities of daily living impaired, chills, face oedema, fatigue, flushing, heart rate increased, hypersensitivity, infusion related reaction, nonspecific reaction. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. Patient recovered.

Myozyme Side Effects Report #5319721-1
Myozyme side effect was reported by a Physician from GERMANY on Apr 18, 2007. Male patient, 59 years of age, weighting 158.7 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: cyanosis, hypersensitivity, infusion related reaction. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with ATACAND, CARMEN. Patient recovered.

Myozyme Side Effects Report #5319722-3
Myozyme side effect was reported by a Physician from GERMANY on Apr 18, 2007. Female patient, 51 years of age, weighting 158.7 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: hypersensitivity, hypotension, infusion related reaction. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with ENTHYROX. Patient recovered.

Myozyme Side Effects Report #5761739-9
Myozyme side effect was reported by a Health Professional from UNITED STATES on May 16, 2008. Female patient, 48 years of age, weighting 165.8 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: cardiac disorder, chest discomfort, contusion, dyspnoea, hypersensitivity, infusion related reaction, septal panniculitis. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. During the same period patient was treated with DIPHENHYDRAMINE, SYNTHROID, VESICARE, ZOLOFT. Patient recovered.


Myozyme Side Effects Report #5775965-6
Myozyme side effect was reported by a Physician from UNITED STATES on May 30, 2008. Female patient, 48 years of age, weighting 165.8 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood pressure increased, chest discomfort, dyspnoea, flushing, hypersensitivity, throat tightness. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. During the same period patient was treated with DIPHENHYDRAMINE, SYNTHROID, VESICARE, ZOLOFT. Patient recovered.

Myozyme Side Effects Report #5933430-7
Myozyme side effect was reported by a Physician from UNITED STATES on Oct 16, 2008. Female patient, 48 years of age, weighting 165.3 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood pressure increased, chest discomfort, dyspnoea, flushing, hypersensitivity, throat tightness. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. During the same period patient was treated with DIPHENHYDRAMINE, SYNTHROID, VESICARE, ZOLOFT. Patient recovered.

Myozyme Side Effects Report #5681125-X
Myozyme side effect was reported by a Physician from GERMANY on Mar 11, 2008. Female patient, 36 years of age, weighting 147.7 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: cough, dyspnoea, hypersensitivity, infusion related reaction, obstructive airways disorder, stridor. Myozyme dosage: unknown. During the same period patient was treated with RANITIDINE, FENISTIL, PREDNISOLONE, EFEROX, ORGAMETRIL, LYRICA. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #5755486-7
Myozyme side effect was reported by a Physician from GERMANY on May 19, 2008. Female patient, 36 years of age, weighting 147.7 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: dyspnoea, hypersensitivity, infusion related reaction, stridor. Myozyme dosage: unknown. During the same period patient was treated with RANITIDINE, FENISTIL, PREDNSOLON, EFEROX, ORGAMETRIL, LYRICA. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #5383418-2
Myozyme side effect was reported by a Physician from GERMANY on June 25, 2007. Female patient, 35 years of age, weighting 149.9 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: asthma , dyspnoea, hypersensitivity. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with EFEROX, ORGAMETRIL, LYRICA. Patient recovered.


Myozyme Side Effects Report #5336329-2
Myozyme side effect was reported by a Physician from UNITED STATES on May 09, 2007. Female patient, 33 years of age, weighting 160.9 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: chest discomfort, dizziness , dyspnoea, flushing, headache , hypersensitivity, nausea , oxygen saturation decreased, peak expiratory flow rate decreased. Myozyme dosage: 10 MG/KG QWK IV. During the same period patient was treated with PREDNISONE, SYNTHROID, NAPROXEN, HYDROCODONE BITARTRATE, HYDROCORTISONE. Patient recovered.

Myozyme Side Effects Report #5372686-9
Myozyme side effect was reported by a Physician from AUSTRALIA on June 12, 2007. Female patient, child 3 years of age, weighting 34.39 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood pressure systolic decreased, cyanosis, gait disturbance, hypersensitivity, hypotonia. Myozyme dosage: 20 MG/KG QW2KS IV. During the same period patient was treated with ALPHA. Patient recovered.

Myozyme Side Effects Report #5166543-0
Myozyme side effect was reported by a Physician from TURKEY on Nov 15, 2006. Female patient, 28 years of age, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: dyspnoea, hypersensitivity, infusion related reaction, rash . Myozyme dosage: unknown. Patient recovered.

Myozyme Side Effects Report #5849650-6
Myozyme side effect was reported by a Physician from JAPAN on Aug 13, 2008. Female patient, child 10 years of age, weighting 48.50 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: asthma , cough, hypersensitivity, infusion related reaction, stridor, urticaria. Myozyme dosage: 450 MG, Q2W, INTRAVENOUS. Patient recovered.

Myozyme Side Effects Report #5856550-4
Myozyme side effect was reported by a Physician from JAPAN on Aug 11, 2008. Female patient, child 10 years of age, weighting 48.50 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: asthma , hypersensitivity, urticaria. Myozyme dosage: 450 MG, Q2W, INTRAVENOUS. Patient recovered.


Myozyme Side Effects Report #5945823-2
Myozyme side effect was reported by a Physician from JAPAN on Oct 22, 2008. Female patient, child 10 years of age, weighting 48.50 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: asthma , hypersensitivity, infusion related reaction, urticaria. Myozyme dosage: 450 MG, Q2W, INTRAVENOUS. Patient recovered.

Myozyme Side Effects Report #5245892-1
Myozyme side effect was reported by a Physician from UNITED STATES on Feb 01, 2007. Male patient, weighting 15.21 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood magnesium increased, blood pressure decreased, cardio-respiratory arrest, heart rate decreased, hypersensitivity, infection , infusion related reaction, respiratory distress, respiratory rate increased. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with DIPHENHYDRAMINE, ACETAMINOPHEN, POTASSIUM CHLORIDE, FAMOTIDINE, DIGOXIN, PROPRANOLOL, FUROSEMIDE, HYDROCHLOROTHIAZIDE. Patient recovered.

Myozyme Side Effects Report #5254712-0
Myozyme side effect was reported by a Physician from UNITED STATES on Feb 12, 2007. Male patient, weighting 15.21 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood magnesium increased, blood pressure decreased, cardio-respiratory arrest, cough, crying, hypersensitivity, infection , pyrexia, respiratory distress. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with DIPHENHYDRAMINE, ACETAMINOPHEN, POTASSIUM CHLORIDE, FAMOTIDINE, DIGOXIN, PROPRANOLOL, FUROSEMIDE. Patient recovered.

Myozyme Side Effects Report #5714330-4
Myozyme side effect was reported by a Physician from ISRAEL on Apr 10, 2008. Male patient, weighting 21.83 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: bronchospasm, cyanosis, dyspnoea, hypersensitivity, oxygen saturation decreased. Myozyme dosage: 200 MG, Q2W, INTRAVENOUS. During the same period patient was treated with FUROSEMIDE, CAPTOPRIL. Patient recovered.

Myozyme Side Effects Report #5724720-1
Myozyme side effect was reported by a Health Professional from ISRAEL on Apr 18, 2008. Male patient, weighting 21.83 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: bronchospasm, cyanosis, dyspnoea, hypersensitivity, oxygen saturation decreased. Myozyme dosage: 200 MG, Q2W, INTRAVENOUS. During the same period patient was treated with FUROSEMIDE, CAPTOPRIL. Patient recovered.


Myozyme Side Effects Report #5747234-1
Myozyme side effect was reported by a Physician from ISRAEL on Apr 27, 2008. Male patient, weighting 21.83 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: bronchospasm, cyanosis, dyspnoea, hypersensitivity, oxygen saturation decreased. Myozyme dosage: 200 MG, Q2W, INTRAVENOUS. During the same period patient was treated with FUROSEMIDE, CAPTOPRIL. Patient recovered.

Myozyme Side Effects Report #5753890-4
Myozyme side effect was reported by a Physician from CROATIA (local name: Hrvatska) on May 16, 2008. Female patient, weighting 18.52 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: bronchial obstruction, dyspnoea, hypersensitivity, oxygen saturation decreased, tachycardia, tachypnoea. Myozyme dosage: 200 MG, Q2W; INTRAVENOUS. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #5919121-7
Myozyme side effect was reported by a Physician from TAIWAN, PROVINCE OF CHINA on Oct 01, 2008. Male patient, weighting 19.84 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood pressure diastolic decreased, body temperature decreased, cough, heart rate increased, hypersensitivity, irritability, oxygen saturation decreased, rhinorrhoea, tachypnoea. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS; 15 MG/KG, QW, INTRAVENOUS; 10MG/KG, QW, INTRAVENOUS;. During the same period patient was treated with VENA, PREDNISONE. Patient recovered.

Myozyme Side Effects Report #5930343-1
Myozyme side effect was reported by a Physician from CROATIA (local name: Hrvatska) on Oct 17, 2008. Female patient, weighting 18.52 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: bronchial obstruction, dyspnoea, hypersensitivity, oxygen saturation decreased, tachycardia, tachypnoea. Myozyme dosage: 200 MG, Q2W, INTRAVENOUS. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #5945822-0
Myozyme side effect was reported by a Physician from CROATIA (local name: Hrvatska) on Oct 24, 2008. Female patient, weighting 18.52 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: bronchial obstruction, dyspnoea, hypersensitivity, oxygen saturation decreased, tachycardia, tachypnoea. Myozyme dosage: 200 MG, Q2W, INTRAVENOUS. Patient was hospitalized. Patient recovered.


Myozyme Side Effects Report #5988374-1
Myozyme side effect was reported by a Physician from CROATIA (local name: Hrvatska) on Nov 24, 2008. Female patient, weighting 18.52 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: agitation, blood pressure increased, bronchial obstruction, bronchospasm, dyspnoea, hypersensitivity, infusion related reaction, irritability. Myozyme dosage: 200 MG, QW, INTRAVENOUS : 200 MG, Q2W, INTRAVENOUS. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #5995076-4
Myozyme side effect was reported by a Physician from CROATIA (local name: Hrvatska) on Dec 05, 2008. Female patient, weighting 18.52 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: agitation, blood pressure increased, bronchial obstruction, bronchospasm, dyspnoea, hypersensitivity, irritability, nosocomial infection, oxygen saturation decreased. Myozyme dosage: 200 MG, Q2W, INTRAVENOUS. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #6030969-3
Myozyme side effect was reported by a Physician from CROATIA (local name: Hrvatska) on Dec 15, 2008. Female patient, weighting 18.52 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: agitation, blood pressure increased, bronchial obstruction, bronchospasm, hypersensitivity, infusion related reaction, irritability, no therapeutic response, nosocomial infection. Myozyme dosage: 200 MG, Q2W, INTRAVENOUS. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #6055095-9
Myozyme side effect was reported by a Physician from GREECE on Jan 15, 2009. Male patient, weighting 17.64 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood pressure decreased, cyanosis, hypersensitivity, infusion related reaction. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. Patient recovered.

Myozyme Side Effects Report #6094701-X
Myozyme side effect was reported by a Physician from GREECE on Feb 13, 2009. Male patient, weighting 17.64 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood pressure decreased, cyanosis, disease recurrence, hypersensitivity, infusion related reaction. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. Patient was hospitalized. Patient recovered.


Myozyme Side Effects Report #6111297-4
Myozyme side effect was reported by a Physician from GREECE on Feb 27, 2009. Male patient, weighting 17.64 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: cyanosis, erythema, hypersensitivity, hypotension, infusion related reaction, pruritus, rash . Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. Patient was hospitalized. Patient recovered.