Myozyme and diarrhoea 
Myozyme and diarrhoea Patient Reports February 13, 2012
Myozyme Side Effects Report #5942624-6
Myozyme side effect was reported by a Physician from ISRAEL on Oct 22, 2008. Female patient, child 6 years of age, weighting 39.68 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: abdominal pain
, asthenia, chills, developmental delay, diarrhoea, face oedema, fatigue, flushing, immunology test abnormal. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. Patient recovered.Myozyme Side Effects Report #5975239-4
Myozyme side effect was reported by a Physician from ISRAEL on Nov 17, 2008. Female patient, child 6 years of age, weighting 41.45 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: abdominal pain
, asthenia, developmental delay, diarrhoea, face oedema, irritability, no therapeutic response, refusal of treatment by relative, urticaria. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. Patient recovered.Myozyme Side Effects Report #5975623-9
Myozyme side effect was reported by a Physician from ISRAEL on Nov 17, 2008. Female patient, child 6 years of age, weighting 41.45 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: abdominal pain
, asthenia, developmental delay, diarrhoea, face oedema, irritability, muscular weakness, myopathy, no therapeutic response. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. Patient recovered.Myozyme Side Effects Report #6051071-0
Myozyme side effect was reported by a Physician from ISRAEL on Jan 12, 2009. Female patient, child 6 years of age, weighting 41.45 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: abdominal pain
, asthenia, developmental delay, diarrhoea, face oedema, irritability, no therapeutic response, urticaria, vomiting. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. Patient recovered.Myozyme Side Effects Report #5205596-8
Myozyme side effect was reported by a Physician from UNITED STATES on Aug 14, 2006. Female patient, 44 years of age, weighting 137.8 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: abdominal pain upper, diarrhoea, headache
, nausea . Myozyme dosage: 20 MG/KG Q2WKS; IV. Patient recovered.Myozyme Side Effects Report #6140345-0
Myozyme side effect was reported by a Physician from TAIWAN, PROVINCE OF CHINA on Mar 19, 2009. Female patient, child 4 years of age, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: anaemia, ascites, blood gases abnormal, candidiasis, cholelithiasis, diarrhoea, hepatic function abnormal, humerus fracture, hypercapnia. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. Patient recovered.
Myozyme Side Effects Report #5454997-1
Myozyme side effect was reported by a Physician from AUSTRALIA on Aug 30, 2007. Female patient, child 3 years of age, weighting 33.73 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased, diarrhoea, dysphagia, fall
, fatigue, muscular weakness. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with ALPHA. Patient recovered.Myozyme Side Effects Report #5474472-8
Myozyme side effect was reported by a Physician from TAIWAN, PROVINCE OF CHINA on Sept 13, 2007. Male patient, child 3 years of age, weighting 32.85 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, application site vesicles, aspartate aminotransferase increased, bedridden, blood lactate dehydrogenase increased, bone density decreased, diarrhoea, eczema
, gastroenteritis rotavirus. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with ALPHA, AMBROXOL, CARDIOLOL, ISOMIL, BIOCAL. Patient was hospitalized and became disabled. Patient recovered.Myozyme Side Effects Report #6112213-1
Myozyme side effect was reported by a Health Professional from UNITED STATES on Feb 26, 2009. Male patient, child 2 years of age, weighting 28.66 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: central line infection, diarrhoea, gastroenteritis viral, nausea
, pyrexia, retching, salivary hypersecretion, staphylococcal infection , tracheobronchitis. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS; 30 MG/KG, Q2W, INTRAVENOUS; 40 MG/KG, Q2W, INTRAVENOUS. During the same period patient was treated with BENADRYL, ACETAMINOPHEN. Patient was hospitalized. Patient recovered.Myozyme Side Effects Report #6138952-4
Myozyme side effect was reported by a Health Professional from UNITED STATES on Mar 20, 2009. Male patient, child 2 years of age, weighting 28.66 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: central line infection, diarrhoea, gastroenteritis viral, nausea
, retching, salivary hypersecretion, staphylococcal infection , tracheobronchitis. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS; 30 MG/KG, Q2W, INTRAVENOUS; 40 MG/KG, Q2W, INTRAVENOUS . During the same period patient was treated with BENADRYL, ACETAMINOPHEN. Patient was hospitalized. Patient recovered.Myozyme Side Effects Report #5203378-4
Myozyme side effect was reported by a Physician from GREECE on Dec 22, 2006. Female patient, weighting 17.64 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: abdominal infection, alanine aminotransferase increased, aspartate aminotransferase increased, cardiac disorder, cardiac index increased, cardio-respiratory arrest, diarrhoea, lower respiratory tract infection. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with ALPHA, HCL THIAZIDE, SPIRONOLACTONE, DIGITALIS, ENALAPRIL MALEATE. Patient was hospitalized. Patient died on 12/29/2006.
Myozyme Side Effects Report #5229673-0
Myozyme side effect was reported by a Physician from GREECE on Jan 18, 2007. Female patient, weighting 17.64 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: abdominal infection, alanine aminotransferase increased, aspartate aminotransferase increased, blood immunoglobulin g increased, cardio-respiratory arrest, cardiopulmonary failure, cyanosis, diarrhoea, dilatation ventricular. Myozyme dosage: 20 MG/KG QWK IV. During the same period patient was treated with ALPHA, HCL THIAZIDE, SPIRONOLACTONE, DIGITALIS, ENALAPRIL MALEATE. Patient was hospitalized. Patient died on 12/29/2006.
Myozyme Side Effects Report #5290127-7
Myozyme side effect was reported by a Physician from GREECE on Mar 16, 2007. Female patient, weighting 17.64 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: abdominal infection, alanine aminotransferase increased, antibody test positive, aspartate aminotransferase increased, cardio-respiratory arrest, cardiopulmonary failure, cyanosis, diarrhoea, disease progression. Myozyme dosage: 20 MG/KG QWK IV. During the same period patient was treated with ALPHA, HCL THIAZIDE, SPIRONOLACTONE, DIGITALIS, ENALAPRIL MALEATE. Patient was hospitalized. Patient died on 12/29/2006.
Myozyme Side Effects Report #5154619-3
Myozyme side effect was reported by a Physician from GREECE on Oct 30, 2006. Female patient was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: cardiac function test abnormal, cardiac ventricular disorder, diarrhoea, pyrexia, weight decreased. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with CARDIAC SUPPORTIVE TREATMENT. Patient was hospitalized. Patient recovered.
Myozyme Side Effects Report #5160838-2
Myozyme side effect was reported by a Physician from GREECE on Nov 09, 2006. Female patient, weighting 17.64 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: abdominal infection, alanine aminotransferase increased, aspartate aminotransferase increased, cardiac disorder, cardiac ventricular disorder, condition aggravated, diarrhoea, mood altered. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with HCL THIAZIDE, SPIRONOLACTONE, DIGITALIS, ENALAPRIL MALEATE. Patient was hospitalized. Patient recovered.
Myozyme Side Effects Report #5510571-X
Myozyme side effect was reported by a Physician from UNITED STATES on Oct 23, 2007. Female patient, weighting 29.98 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: acinetobacter infection, bacteria urine identified, blood ph increased, blood pressure diastolic decreased, diarrhoea, enterococcal infection, escherichia infection, heart rate increased, hydronephrosis. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with ALPHA, PREVACID, ENALAPRIL MALEATE, DIGOXIN, MIRALAX, LASIX. Patient was hospitalized. Patient recovered.
Myozyme Side Effects Report #5556366-2
Myozyme side effect was reported by a Physician from UNITED STATES on Nov 27, 2007. Female patient was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: cardiac failure, catheter sepsis, cerebral ischaemia, condition aggravated, dehydration, diarrhoea, disease recurrence, disseminated intravascular coagulation, feeding disorder. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with ALPHA. Patient was hospitalized. Patient died on 11/29/2007.
Myozyme Side Effects Report #5663287-3
Myozyme side effect was reported by a Physician from BRAZIL on Feb 26, 2008. Male patient was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: circulatory collapse, convulsion, cyanosis, diarrhoea. Myozyme dosage: 20 MG/KG, Q2W. During the same period patient was treated with CAPTOPRIL, FUROSEMIDE. Patient was hospitalized. Patient recovered.
Myozyme Side Effects Report #5679713-X
Myozyme side effect was reported by a Physician from BRAZIL on Mar 07, 2008. Male patient was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: brain hypoxia, cardiac arrest
, circulatory collapse, convulsion, cyanosis, diarrhoea. Myozyme dosage: 20 MG/KG, Q2W. During the same period patient was treated with CAPTOPRIL, FUROSEMIDE. Patient was hospitalized. Patient died on 03/06/2008.Myozyme Side Effects Report #5679717-7
Myozyme side effect was reported by a Physician from BRAZIL on Mar 07, 2008. Male patient was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: brain hypoxia, cardiac arrest
, circulatory collapse, convulsion, cyanosis, diarrhoea, haemodynamic instability. Myozyme dosage: 20 MG/KG, Q2W. During the same period patient was treated with CAPTOPRIL, FUROSEMIDE. Patient was hospitalized. Patient died on 03/06/2008.Myozyme Side Effects Report #5795978-8
Myozyme side effect was reported by a Health Professional from UNITED STATES on June 20, 2008. Female patient, weighting 7.94 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: catheter placement, diarrhoea, oxygen saturation decreased, vomiting. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. Patient was hospitalized. Patient recovered.
Myozyme Side Effects Report #5829500-4
Myozyme side effect was reported by a Physician from UNITED STATES on July 16, 2008. Female patient, weighting 7.94 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood immunoglobulin g increased, catheter placement, diarrhoea, oxygen saturation decreased, vomiting. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. Patient was hospitalized. Patient recovered.
Myozyme Side Effects Report #6106803-X
Myozyme side effect was reported by a Physician from UNITED ARAB EMIRATES on Feb 22, 2009. Male patient was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: diarrhoea, erythema, lung infection, rash erythematous, wheezing. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. During the same period patient was treated with STEROIDS, PARACETAMOL, PREDNISOLONE, METHYLPREDNISOLONE, ANTIHISTAMINES, HYDROCORTISONE, ACETAMINOPHEN, ZANTAC. Patient was hospitalized. Patient recovered.
Myozyme Side Effects Report #6131096-7
Myozyme side effect was reported by a Physician from UNITED ARAB EMIRATES on Mar 10, 2009. Male patient was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: agitation, blood immunoglobulin g increased, diarrhoea, dysphagia, erythema, hypotonia, infusion related reaction, lung infection. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. During the same period patient was treated with STEROIDS, ACETAMINOPHEN, PREDNISOLONE, METHYLPREDNISOLONE, ANTIHISTAMINES, HYDROCORTISONE, ZANTAC. Patient was hospitalized. Patient recovered.