Myozyme and condition aggravated 
Myozyme and condition aggravated Patient Reports February 12, 2012
Myozyme Side Effects Report #5909597-3
Myozyme side effect was reported by a Health Professional from UNITED STATES on Sept 26, 2008. Male patient, 66 years of age, weighting 189.2 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: asthenia, blood potassium decreased, condition aggravated, dysphagia, feeling abnormal, hypothyroidism, mastication disorder, mobility decreased, paralysis
. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. During the same period patient was treated with COZAAR, NORVASC, INDAPAMIDE, ZOLOFT, THYROID SUPPLEMENT, POTASSIUM, FISH OIL SUPPLEMENT, VITAMIN. Patient recovered.Myozyme Side Effects Report #5369681-2
Myozyme side effect was reported by a Physician from FRANCE on June 07, 2007. Male patient, 57 years of age, weighting 216.1 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: condition aggravated, fatigue, lung infection, pulmonary congestion, respiratory failure. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with MUCOMYST. Patient was hospitalized. Patient recovered.
Myozyme Side Effects Report #5994141-5
Myozyme side effect was reported by a Health Professional from UNITED KINGDOM on Nov 21, 2008. Female patient, 43 years of age, weighting 105.8 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: anaphylactic reaction, blood pressure decreased, bronchiectasis, cardiac failure, condition aggravated, lung abscess, no therapeutic response, pneumonia
, renal failure. Myozyme dosage: 20 MG/KG, Q2W; INTRAVENOUS. During the same period patient was treated with PEPPERMINT WATER. Patient died on 07/28/2008.Myozyme Side Effects Report #5914009-X
Myozyme side effect was reported by a Physician from FRANCE on Sept 25, 2008. Male patient, 38 years of age, weighting 194.0 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: condition aggravated, mental disorder, psychotic disorder
. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. During the same period patient was treated with RISPERDAL. Patient was hospitalized. Patient recovered.Myozyme Side Effects Report #5947746-1
Myozyme side effect was reported by a Physician from FRANCE on Oct 29, 2008. Male patient, 38 years of age, weighting 194.0 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: condition aggravated, confusional state, delusion, mental disorder, respiratory failure. Myozyme dosage: 20 MG/KG, Q2W; INTRAVENOUS. During the same period patient was treated with RISPERDAL. Patient was hospitalized. Patient died.
Myozyme Side Effects Report #5532913-1
Myozyme side effect was reported by a Physician from UNITED STATES on Nov 14, 2007. Female patient, child 3 years of age, weighting 30.20 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood calcium increased, blood magnesium increased, bone density decreased, brain natriuretic peptide increased, cardiac disorder, cardiomegaly, condition aggravated, culture urine positive, diarrhoea. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with ALPHA, DIGOXIN, ENALAPRIL. Patient was hospitalized. Patient recovered.
Myozyme Side Effects Report #5362829-5
Myozyme side effect was reported by a Physician from UNITED STATES on June 03, 2007. Male patient, 22 years of age, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: arthralgia, condition aggravated, oedema peripheral, pain in extremity, pyrexia. Myozyme dosage: 20 MG/KG Q2WKS IV. Patient was hospitalized. Patient recovered.
Myozyme Side Effects Report #5379544-4
Myozyme side effect was reported by a Physician from UNITED STATES on June 19, 2007. Male patient, 22 years of age, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: condition aggravated, rheumatoid factor increased, serum sickness, synovial fluid white blood cells positive. Myozyme dosage: 20 MG/KG Q2WKS IV. Patient was hospitalized. Patient recovered.
Myozyme Side Effects Report #5455028-X
Myozyme side effect was reported by a Physician from CHINA on Aug 30, 2007. Female patient, child 2 years of age, weighting 13.87 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: cardiac failure, condition aggravated, disease recurrence, muscular weakness, myocardial ischaemia, no therapeutic response, nodal arrhythmia, pneumonia
, ventricular extrasystoles. Myozyme dosage: 20 MG/KG Q2WKS IV. Patient recovered.Myozyme Side Effects Report #5512664-X
Myozyme side effect was reported by a Physician from CHINA on Oct 22, 2007. Female patient, child 2 years of age, weighting 13.87 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: acinetobacter infection, alpha haemolytic streptococcal infection, blood immunoglobulin g increased, blood sodium decreased, cardiac failure, condition aggravated, electrolyte imbalance, fluid retention, gene mutation identification test positive. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with MILRINONE. Patient was hospitalized. Patient recovered.
Myozyme Side Effects Report #5409468-5
Myozyme side effect was reported by a Physician from UNITED STATES on July 24, 2007. Female patient, child 10 years of age, weighting 61.07 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: condition aggravated, scoliosis. Myozyme dosage: unknown. During the same period patient was treated with ALPHA, PULMICORT. Patient was hospitalized. Patient recovered.
Myozyme Side Effects Report #5452124-8
Myozyme side effect was reported by a Physician from UNITED STATES on Aug 29, 2007. Female patient, child 10 years of age, weighting 61.07 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: bacterial infection
, condition aggravated, culture positive, postoperative wound infection, scoliosis. Myozyme dosage: unknown. During the same period patient was treated with ALPHA, PULMICORT. Patient was hospitalized. Patient recovered.Myozyme Side Effects Report #5375663-7
Myozyme side effect was reported by a Health Professional from UNITED STATES on June 18, 2007. Male patient, child 1 years of age, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: abasia, acute respiratory distress syndrome, aspiration, asthenia, atelectasis, condition aggravated, disease progression, disease recurrence, dysphagia. Myozyme dosage: 20 MG/KG Q2WKS; IV. During the same period patient was treated with ALPHA, CAPTOPRIL, STEROIDS. Patient was hospitalized. Patient recovered.
Myozyme Side Effects Report #5375663-7
Myozyme side effect was reported by a Health Professional from UNITED STATES on June 18, 2007. Male patient, child 1 years of age, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: abasia, acute respiratory distress syndrome, aspiration, asthenia, atelectasis, condition aggravated, disease progression, disease recurrence, dysphagia. Myozyme dosage: 20 MG/KG Q2WKS; IV. During the same period patient was treated with ALPHA, CAPTOPRIL, STEROIDS. Patient was hospitalized. Patient recovered.
Myozyme Side Effects Report #5454998-3
Myozyme side effect was reported by a Physician from CHINA on Aug 30, 2007. Female patient, child 1 years of age, weighting 13.87 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood pressure decreased, cardiac failure, condition aggravated, cyanosis, disease recurrence, fluid overload, hyperhidrosis, myocardial ischaemia, nodal arrhythmia. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with CAPTOPRIL, FRUSEMIDE. Patient recovered.
Myozyme Side Effects Report #5564570-2
Myozyme side effect was reported by a Physician from UNITED STATES on Nov 30, 2007. Male patient, child 1 years of age, weighting 21.83 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: alpha haemolytic streptococcal infection, areflexia, aspiration, blood immunoglobulin g increased, blood pressure diastolic decreased, bronchoalveolar lavage abnormal, catheter related infection, condition aggravated, dilatation ventricular. Myozyme dosage: unknown. During the same period patient was treated with RITUXIMAB, METHOTREXATE, IMMUNE GLOBULIN INTRAVENOUS, BENADRYL, TYLENOL, BUDESONIDE. Patient was hospitalized. Patient recovered.
Myozyme Side Effects Report #5209170-9
Myozyme side effect was reported by a Physician from UNITED STATES on Dec 28, 2006. Male patient, weighting 12.13 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: asthenia, blood creatine phosphokinase increased, blood culture positive, candidiasis, central line infection, condition aggravated, enterococcal infection, feeding disorder, hyporeflexia. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with BUDESONIDE, XOPENEX, LANSOPRAZOLE, DIGOXIN, PROPRANOLOL, AMIODARONE. Patient was hospitalized. Patient recovered.
Myozyme Side Effects Report #5247439-2
Myozyme side effect was reported by a Physician from UNITED STATES on Feb 06, 2007. Female patient was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: cardiomyopathy
, condition aggravated, pneumonia , respiratory failure, tracheitis. Myozyme dosage: 20 MG/KG Q2WKS IV. Patient was hospitalized. Patient recovered.Myozyme Side Effects Report #5254709-0
Myozyme side effect was reported by a Physician from UNITED STATES on Feb 12, 2007. Female patient, weighting 21.16 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: asthenia, cardiac failure, condition aggravated, respiratory failure, urinary tract infection
. Myozyme dosage: 200 MG Q2WKS IV. During the same period patient was treated with LASIX, CAPTOPRIL, COREG. Patient was hospitalized. Patient died on 02/15/2007.Myozyme Side Effects Report #5294077-1
Myozyme side effect was reported by a Health Professional from UNITED STATES on Mar 23, 2007. Male patient, weighting 11.68 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: bacteraemia, blepharospasm, blood culture positive, blood immunoglobulin g increased, body temperature decreased, bronchial hyperreactivity, central line infection, condition aggravated, device related infection. Myozyme dosage: unknown. During the same period patient was treated with BACTRIM. Patient was hospitalized. Patient recovered.
Myozyme Side Effects Report #5369481-3
Myozyme side effect was reported by a Physician from UNITED STATES on June 06, 2007. Male patient, weighting 16.76 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: anaemia, atelectasis, blood culture positive, cardiac failure acute, condition aggravated, dilatation ventricular, heart rate decreased, lung infiltration. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with UNASYN, FENTANYL. Patient was hospitalized. Patient recovered.
Myozyme Side Effects Report #5148156-X
Myozyme side effect was reported by a Physician from BRAZIL on Oct 23, 2006. Male patient, weighting 16.53 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: bradycardia, cardiac arrest
, cardiac failure, condition aggravated, heart rate increased, pneumonia , respiratory rate increased, shock, ventricular fibrillation. Myozyme dosage: 20 MG/KG ONCE IV. During the same period patient was treated with CAPTOPRIL, FUROSEMIDE. Patient died on 10/23/2006.Myozyme Side Effects Report #5160220-8
Myozyme side effect was reported by a Physician from UNITED STATES on Nov 06, 2006. Male patient was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: condition aggravated, conjunctival hyperaemia, disease progression, erythema, flushing, hypertrophic cardiomyopathy, infusion related reaction, muscular weakness, nausea
. Myozyme dosage: 20 MG/KG Q2WKS IV. Patient recovered.Myozyme Side Effects Report #5160838-2
Myozyme side effect was reported by a Physician from GREECE on Nov 09, 2006. Female patient, weighting 17.64 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: abdominal infection, alanine aminotransferase increased, aspartate aminotransferase increased, cardiac disorder, cardiac ventricular disorder, condition aggravated, diarrhoea, mood altered. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with HCL THIAZIDE, SPIRONOLACTONE, DIGITALIS, ENALAPRIL MALEATE. Patient was hospitalized. Patient recovered.
Myozyme Side Effects Report #5383593-X
Myozyme side effect was reported by a Physician from MALAYSIA on June 27, 2007. Female patient, weighting 13.23 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: asthma
, condition aggravated, pneumonia aspiration, ventricular fibrillation. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with SALBUTAMOL, HYDROCORTISONE, ANTIBIOTICS, FUROSEMIDE. Patient died on 06/12/2007.Myozyme Side Effects Report #5383665-X
Myozyme side effect was reported by a Physician from UNITED STATES on June 25, 2007. Male patient, weighting 16.76 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: anaemia, cardiac failure acute, chest x-ray abnormal, condition aggravated, dilatation ventricular, heart rate decreased, oxygen saturation decreased, rash erythematous. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with UNASYN, FENTANYL TRANSDERMAL SYSTEM. Patient was hospitalized. Patient recovered.
Myozyme Side Effects Report #5390882-1
Myozyme side effect was reported by a Health Professional from UNITED STATES on July 02, 2007. Male patient was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: abasia, aspiration, asthenia, atelectasis, blood immunoglobulin g increased, condition aggravated, disease progression, dysphagia, glycogen storage disease type ii. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with ALPHA, CAPTOPRIL, STEROIDS. Patient was hospitalized. Patient died on 06/30/2007.
Myozyme Side Effects Report #5556366-2
Myozyme side effect was reported by a Physician from UNITED STATES on Nov 27, 2007. Female patient was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: cardiac failure, catheter sepsis, cerebral ischaemia, condition aggravated, dehydration, diarrhoea, disease recurrence, disseminated intravascular coagulation, feeding disorder. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with ALPHA. Patient was hospitalized. Patient died on 11/29/2007.
Myozyme Side Effects Report #5566507-9
Myozyme side effect was reported by a Health Professional from UNITED STATES on Nov 30, 2007. Male patient, weighting 11.68 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: bacteria stool identified, bronchial hyperreactivity, central line infection, condition aggravated, enterobacter bacteraemia, eyelid function disorder, haemoglobin decreased, lobar pneumonia, nystagmus. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with BACTRIM, RITUXIMAB, METHOTREXATE, BENADRYL, TYLENOL. Patient was hospitalized. Patient recovered.
Myozyme Side Effects Report #5566517-1
Myozyme side effect was reported by a Physician from UNITED STATES on Nov 30, 2007. Male patient, weighting 15.38 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: areflexia, bronchial hyperreactivity, candidiasis, central line infection, cleft lip
, coagulopathy, condition aggravated, diaphragm muscle weakness, disease progression. Myozyme dosage: 30 MG/KG Q2WKS IV. During the same period patient was treated with METHOTREXATE, RITUXIMAB, IMMUNE GLOBULIN INTRAVENOUS. Patient was hospitalized. Patient recovered.Myozyme Side Effects Report #5688181-3
Myozyme side effect was reported by a Physician from BELGIUM on Mar 13, 2008. Female patient was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: condition aggravated, glycogen storage disease type ii, muscular weakness, respiratory failure. Myozyme dosage: unknown. Patient died on 12/21/2007.
Myozyme Side Effects Report #5871196-X
Myozyme side effect was reported by a Physician from UNITED KINGDOM on Aug 15, 2008. Male patient, weighting 13.23 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: cardiac arrest
, cardiac failure, condition aggravated, culture urine positive, hypertrophic cardiomyopathy, hypotonia, hypoxia, oxygen consumption increased, pyrexia. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. Patient died on 05/15/2006.Myozyme Side Effects Report #5885628-4
Myozyme side effect was reported by a Physician from CHINA on Sept 08, 2008. Female patient, weighting 13.89 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: acinetobacter infection, alpha haemolytic streptococcal infection, aspiration tracheal abnormal, blood immunoglobulin g increased, blood sodium decreased, cardiac arrest
, cardiac failure, condition aggravated, disease recurrence. Myozyme dosage: 20 MG/KG, Q2W; INTRAVENOUS. During the same period patient was treated with MILRINONE. Patient was hospitalized. Patient died on 09/06/2008.Myozyme Side Effects Report #5020428-9
Myozyme side effect was reported by a Physician from UNITED STATES on May 23, 2006. Female patient, weighting 39.68 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood calcium increased, condition aggravated, hyperparathyroidism, proteinuria. Myozyme dosage: 40 MG/KG Q2WKS IV. During the same period patient was treated with ATROVENT, XOPENEX, PULMICORT, CAPTOPRIL, ALDACTONE, LASIX. Patient recovered.