Myozyme and blood pressure decreased Patient Reports February 13, 2012

Myozyme Side Effects Report #5753661-9
Myozyme side effect was reported by a Physician from UNITED STATES on May 14, 2008. Female patient, 66 years of age, weighting 191.8 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood pressure decreased, feeling hot, hypersensitivity, oxygen saturation decreased, respiratory distress. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. Patient recovered.

Myozyme Side Effects Report #5753664-4
Myozyme side effect was reported by a Physician from UNITED STATES on May 14, 2008. Female patient, 66 years of age, weighting 191.8 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood pressure decreased, feeling hot, hypersensitivity, oxygen saturation decreased, respiratory distress. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. Patient recovered.

Myozyme Side Effects Report #5216727-8
Myozyme side effect was reported by a Consumer or non-health professional from FRANCE on Jan 04, 2007. Female patient, 45 years of age, weighting 123.5 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: anaphylactic reaction, back pain , blood pressure decreased, chest discomfort, chest pain , erythema, flushing, infusion related reaction, nausea . Myozyme dosage: unknown. During the same period patient was treated with FERROUS SULPHATE, POLARAMINE, TELFAST. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #5154555-2
Myozyme side effect was reported by a Consumer or non-health professional from FRANCE on Oct 31, 2006. Female patient, 44 years of age, weighting 123.5 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: back pain , blood pressure decreased, chest pain , erythema, face oedema, flushing, hypotension. Myozyme dosage: unknown. Patient was hospitalized. Patient recovered.


Myozyme Side Effects Report #5994141-5
Myozyme side effect was reported by a Health Professional from UNITED KINGDOM on Nov 21, 2008. Female patient, 43 years of age, weighting 105.8 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: anaphylactic reaction, blood pressure decreased, bronchiectasis, cardiac failure, condition aggravated, lung abscess, no therapeutic response, pneumonia , renal failure. Myozyme dosage: 20 MG/KG, Q2W; INTRAVENOUS. During the same period patient was treated with PEPPERMINT WATER. Patient died on 07/28/2008.

Myozyme Side Effects Report #5945821-9
Myozyme side effect was reported by a Health Professional from UNITED KINGDOM on Oct 27, 2008. Female patient, 33 years of age, weighting 112.0 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood pressure decreased, chest discomfort, cold sweat, flushing, malaise, pallor. Myozyme dosage: 1000 MG, Q2W, INTRAVENOUS. Patient recovered.

Myozyme Side Effects Report #6081258-2
Myozyme side effect was reported by a Physician from UNITED STATES on Feb 02, 2009. Male patient, child 3 years of age, weighting 37.48 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: agitation, anxiety , blood pressure decreased, bronchospasm, cyanosis, fatigue, feeding tube complication, flushing, heart rate increased. Myozyme dosage: 350 MG, Q2W, INTRAVENOUS. During the same period patient was treated with BENADRYL, ACETAMINOPHEN, DECADRON. Patient recovered.

Myozyme Side Effects Report #6101010-9
Myozyme side effect was reported by a Physician from UNITED STATES on Feb 17, 2009. Male patient, child 3 years of age, weighting 37.48 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: agitation, anxiety , blood pressure decreased, bronchospasm, cyanosis, fatigue, flushing, heart rate increased, hypoxia. Myozyme dosage: 350 MG, Q2W, INTRAVENOUS. During the same period patient was treated with BENADRYL, ACETAMINOPHEN, DECADRON. Patient recovered.

Myozyme Side Effects Report #6125057-1
Myozyme side effect was reported by a Physician from UNITED STATES on Mar 05, 2009. Male patient, child 3 years of age, weighting 37.48 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: agitation, antibody test positive, anxiety , blood pressure decreased, bronchospasm, cyanosis, fatigue, flushing, hypoxia. Myozyme dosage: 350 MG, Q2W, INTRAVENOUS. During the same period patient was treated with BENADRYL, ACETAMINOPHEN, DECADRON. Patient recovered.


Myozyme Side Effects Report #6137899-7
Myozyme side effect was reported by a Physician from UNITED STATES on Mar 17, 2009. Male patient, child 3 years of age, weighting 37.48 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: agitation, anxiety , blood pressure decreased, bronchospasm, cyanosis, fatigue, flushing, heart rate increased, hypoxia. Myozyme dosage: 350 MG, Q2W, INTRAVENOUS. During the same period patient was treated with BENADRYL, ACETAMINOPHEN, DECADRON. Patient recovered.

Myozyme Side Effects Report #6024105-7
Myozyme side effect was reported by a Physician from UNITED STATES on Dec 18, 2008. Male patient, 23 years of age, weighting 56.44 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: atrial fibrillation , blood glucose increased, blood potassium decreased, blood pressure decreased, bradycardia, bundle branch block left, coma, respiratory arrest, respiratory distress. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS, 20 MG/KG, Q2W, INTRAVENOUS. Patient was hospitalized. Patient died on 12/19/2008.

Myozyme Side Effects Report #5285772-9
Myozyme side effect was reported by a Health Professional from UNITED STATES on Nov 01, 2006. Male patient, 21 years of age, weighting 73.19 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood pressure decreased, heart rate decreased. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with VITAMIN. Patient recovered.

Myozyme Side Effects Report #5330164-7
Myozyme side effect was reported by a Health Professional from UNITED STATES on May 01, 2007. Male patient, 13 years of age, weighting 123.0 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood pressure decreased, chest discomfort, flushing, hyperhidrosis, respiratory tract irritation, spinal disorder, supraventricular tachycardia, weight increased. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with ALPHA. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #5454998-3
Myozyme side effect was reported by a Physician from CHINA on Aug 30, 2007. Female patient, child 1 years of age, weighting 13.87 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood pressure decreased, cardiac failure, condition aggravated, cyanosis, disease recurrence, fluid overload, hyperhidrosis, myocardial ischaemia, nodal arrhythmia. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with CAPTOPRIL, FRUSEMIDE. Patient recovered.


Myozyme Side Effects Report #5245892-1
Myozyme side effect was reported by a Physician from UNITED STATES on Feb 01, 2007. Male patient, weighting 15.21 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood magnesium increased, blood pressure decreased, cardio-respiratory arrest, heart rate decreased, hypersensitivity, infection , infusion related reaction, respiratory distress, respiratory rate increased. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with DIPHENHYDRAMINE, ACETAMINOPHEN, POTASSIUM CHLORIDE, FAMOTIDINE, DIGOXIN, PROPRANOLOL, FUROSEMIDE, HYDROCHLOROTHIAZIDE. Patient recovered.

Myozyme Side Effects Report #5254712-0
Myozyme side effect was reported by a Physician from UNITED STATES on Feb 12, 2007. Male patient, weighting 15.21 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood magnesium increased, blood pressure decreased, cardio-respiratory arrest, cough, crying, hypersensitivity, infection , pyrexia, respiratory distress. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with DIPHENHYDRAMINE, ACETAMINOPHEN, POTASSIUM CHLORIDE, FAMOTIDINE, DIGOXIN, PROPRANOLOL, FUROSEMIDE. Patient recovered.

Myozyme Side Effects Report #5314669-0
Myozyme side effect was reported by a Physician from UNITED STATES on Apr 12, 2007. Female patient, weighting 17.42 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: bacteraemia, blood culture positive, blood pressure decreased, candidiasis, cardiac murmur, catheter related infection, enterococcal infection, escherichia infection, febrile convulsion. Myozyme dosage: unknown. During the same period patient was treated with PROPRANOLOL. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #5093635-7
Myozyme side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 15, 2006. Male patient, weighting 16.53 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood immunoglobulin e increased, blood immunoglobulin g increased, blood pressure decreased, infusion related reaction, tachycardia, urticaria. Myozyme dosage: 20 MG/KG Q2WKS IV. During the same period patient was treated with ALPHA, CLARINEX, DIPHENHYDRAMINE, RANITIDINE, XOPENEX, PULMICORT, REGLAN. Patient recovered.

Myozyme Side Effects Report #5425043-0
Myozyme side effect was reported by a Consumer or non-health professional from UNITED STATES on June 18, 2007. Female patient, weighting 14.88 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood pressure decreased, pneumonia . Myozyme dosage: 150 MG Q2WKS; IV. Patient was hospitalized. Patient recovered.


Myozyme Side Effects Report #5754824-9
Myozyme side effect was reported by a Physician from TAIWAN, PROVINCE OF CHINA on May 12, 2008. Male patient, weighting 19.84 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood pressure decreased, body temperature decreased, disease recurrence, heart rate increased, irritability, oxygen saturation decreased, respiratory rate increased, tachypnoea. Myozyme dosage: 10 MG/KG, QW, INTRAVENOUS, 20 MG/KG, Q2W, INTRAVENOUS. During the same period patient was treated with VENA, PREDNISOLONE. Patient recovered.

Myozyme Side Effects Report #5796377-5
Myozyme side effect was reported by a Physician from UNITED STATES on June 18, 2008. Male patient, weighting 12.13 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood pressure decreased, cardiac murmur, congestive cardiomyopathy, conjunctivitis, erythema, fatigue, heart rate increased, hypercapnia, hypotonia. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. During the same period patient was treated with LASIX, OXYGEN, ACETAMINOPHEN, MOTRIN. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #5875731-7
Myozyme side effect was reported by a Physician from UNITED STATES on Aug 27, 2008. Male patient, weighting 20.06 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: agitation, blood immunoglobulin g increased, blood pressure decreased, crying, hyperhidrosis, infusion related reaction, nasal congestion, oxygen saturation decreased, pallor. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. During the same period patient was treated with RANITIDINE, PREDNISONE, CETIRIZINE, XOPENEX, PULMICORT, IPRATROPIUM BR, METOCLOPRAMIDE, FLUCONAZOLE. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #5957848-1
Myozyme side effect was reported by a Physician from UNITED STATES on Nov 01, 2008. Male patient, weighting 22.05 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: acute respiratory failure, agitation, blood pressure decreased, clostridium difficile toxin test positive, collapse of lung, crying, diaphragmatic paralysis, gastrostomy tube insertion, grunting. Myozyme dosage: 250 MG, Q2W, INTRAVENOUS. During the same period patient was treated with BUDESONIDE, CETRIZINE, DNASE, IPRATROPIUM BROMIDE, LEVALBUTEROL, LORAZEPAM, RANITIDINE, CROMOLYN. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #6052485-5
Myozyme side effect was reported by a Physician from UNITED STATES on Jan 14, 2009. Female patient, weighting 17.42 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: bacteraemia, blood immunoglobulin g increased, blood pressure decreased, cardiac murmur, catheter related infection, enterococcal infection, escherichia infection, febrile convulsion, heart rate increased. Myozyme dosage: 20 MG/KG, INTRAVENOUS. Patient was hospitalized. Patient recovered.


Myozyme Side Effects Report #6055095-9
Myozyme side effect was reported by a Physician from GREECE on Jan 15, 2009. Male patient, weighting 17.64 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood pressure decreased, cyanosis, hypersensitivity, infusion related reaction. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. Patient recovered.

Myozyme Side Effects Report #6077626-5
Myozyme side effect was reported by a Physician from GREECE on Jan 29, 2009. Male patient, weighting 17.64 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood pressure decreased, cyanosis, infusion related reaction, tryptase increased. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #6088518-X
Myozyme side effect was reported by a Physician from GREECE on Feb 12, 2009. Male patient, weighting 17.64 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood pressure decreased, cyanosis, infusion related reaction. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. Patient was hospitalized. Patient recovered.

Myozyme Side Effects Report #6094701-X
Myozyme side effect was reported by a Physician from GREECE on Feb 13, 2009. Male patient, weighting 17.64 lb, was diagnosed with glycogen storage disease type ii and was treated with Myozyme. After drug was administered, patient experienced the following side effects: blood pressure decreased, cyanosis, disease recurrence, hypersensitivity, infusion related reaction. Myozyme dosage: 20 MG/KG, Q2W, INTRAVENOUS. Patient was hospitalized. Patient recovered.