Methotrexate and sepsis Patient Reports February 11, 2012

Methotrexate Side Effects Report #4719192-X
Methotrexate side effect was reported by a Consumer or non-health professional from on June 21, 2005. Male patient, 62 years of age, weighting 105.8 lb, was diagnosed with squamous cell carcinoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: hyponatraemia, hypotension, pneumonia , sepsis , septic shock, white blood cell count decreased. Methotrexate dosage: 62 MG WEEK IV. During the same period patient was treated with MORPHINE. Patient was hospitalized and became disabled. Patient recovered.

Methotrexate Side Effects Report #4619401-1
Methotrexate side effect was reported by a Consumer or non-health professional from on Oct 01, 2001. Female patient, 79 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: agranulocytosis, anaemia, bacteria blood identified, lobar pneumonia, pneumonia klebsiella, sepsis , thrombocytopenia. Methotrexate dosage: 7.5 MG WEEKLY PO. During the same period patient was treated with ALDRENONATE, PREDNISOLONE, SIMVASTATIN, LANSOPRAZOLE, CALCIUM GLUCONATE, DIPYRIDAMOLE, PARACETAMOL WITH CODEINE. Patient was hospitalized. Patient died on 06/15/2001.

Methotrexate Side Effects Report #4738226-X
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on June 24, 2005. Female patient, 79 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: pancytopenia, renal failure acute, sepsis . Methotrexate dosage: 2.5 MG PO. During the same period patient was treated with FUROSEMIDE, DICLOFENAC, FOLIC ACID, ALENDRONIC ACID. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #5462937-4
Methotrexate side effect was reported by a Health Professional from FRANCE on Sept 17, 2007. Female patient, 77 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: agranulocytosis, sepsis . Methotrexate dosage: unknown. Patient was hospitalized. Patient recovered.


Methotrexate Side Effects Report #5491297-8
Methotrexate side effect was reported by a Consumer or non-health professional from on Oct 17, 2007. Female patient, 77 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: agranulocytosis, sepsis . Methotrexate dosage: unknown. Patient recovered.

Methotrexate Side Effects Report #5427353-X
Methotrexate side effect was reported by a Health Professional from AUSTRIA on Aug 27, 2007. Female patient, 76 years of age, was diagnosed with rheumatoid arthritis , pain management and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: candidiasis, lobar pneumonia, myelodysplastic syndrome, sepsis . Methotrexate dosage: PATIENT RECEIVED INITIALLY ORAL METHOTREXATE 7.5 MG WEEKLY.. During the same period patient was treated with DIPYRONE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4843043-6
Methotrexate side effect was reported by a Physician from GERMANY on Nov 16, 2005. Female patient, 71 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: accidental overdose, multi-organ failure, pancytopenia, pneumonia , sepsis . Methotrexate dosage: 100 MG TOTAL PO. Patient died.

Methotrexate Side Effects Report #4859889-4
Methotrexate side effect was reported by a Consumer or non-health professional from GERMANY on Dec 06, 2005. Female patient, 71 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: incorrect dose administered, multi-organ failure, overdose, pancytopenia, pneumonia , sepsis . Methotrexate dosage: 100 MG IN 8 DAYS (2 X 50 MG) (NR), PO. Patient was hospitalized. Patient died on 01/01/1999.

Methotrexate Side Effects Report #4902699-X
Methotrexate side effect was reported by a Health Professional from GERMANY on Jan 23, 2006. Female patient, 71 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: incorrect dose administered, overdose, pancytopenia, pneumonia , sepsis . Methotrexate dosage: unknown. Patient was hospitalized. Patient died.


Methotrexate Side Effects Report #4924655-8
Methotrexate side effect was reported by a Consumer or non-health professional from SWEDEN on Feb 06, 2006. Male patient, 66 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: arthritis bacterial, sepsis . Methotrexate dosage: 12 MILLIGRAM QW ORAL. During the same period patient was treated with HUMIRA, FELODIPINE, NAPROXEN, CITODON, LACTULOSE, FUROSEMIDE, TERAZOSIN HYDROCHLORIDE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4859855-9
Methotrexate side effect was reported by a Consumer or non-health professional from GERMANY on Dec 06, 2005. Male patient, 65 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: herpes simplex , sepsis , stomatitis. Methotrexate dosage: 10 MG, PO. Patient was hospitalized. Patient died on 01/01/1992.

Methotrexate Side Effects Report #4902591-0
Methotrexate side effect was reported by a Health Professional from GERMANY on Jan 23, 2006. Male patient, 65 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: herpes simplex , sepsis , stomatitis. Methotrexate dosage: unknown. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #4798172-2
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Oct 03, 2005. Female patient, 63 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: blood bilirubin increased, neutrophil count decreased, platelet count decreased, renal failure acute, sepsis , white blood cell count decreased. Methotrexate dosage: 7.5 MG WEEKLY PO. During the same period patient was treated with DICLOFENAC, OMEPRAZOLE, ATENOLOL, BENDROFLUAZIDE, AMITRIPTYLINE, FOLIC ACID. Patient recovered.

Methotrexate Side Effects Report #5321081-7
Methotrexate side effect was reported by a Health Professional from INDIA on May 07, 2007. Female patient, 59 years of age, was diagnosed with rheumatoid arthritis , multiple myeloma  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: lung infection pseudomonal, progressive multifocal leukoencephalopathy, reversible posterior leukoencephalopathy syndrome, sepsis . Methotrexate dosage: unknown. During the same period patient was treated with VINCRISTINE SULPHATE, CYCLOPHOSPHAMIDE, MELPHALAN, CORTICOSTEROID. Patient died.


Methotrexate Side Effects Report #5321868-0
Methotrexate side effect was reported by a Consumer or non-health professional from on May 07, 2007. Female patient, 59 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: apallic syndrome, disorientation, hemiparesis, leukoencephalopathy, lung infection pseudomonal, progressive multifocal leukoencephalopathy, reversible posterior leukoencephalopathy syndrome, sepsis , vision blurred. Methotrexate dosage: 7.5 MG WEEKLY X 5 YEARS. Patient died.

Methotrexate Side Effects Report #4993495-6
Methotrexate side effect was reported by a Pharmacist from UNITED STATES on May 04, 2006. Male patient, 59 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, erythema multiforme, pain in extremity, pancytopenia, renal failure, retroperitoneal haemorrhage, sepsis . Methotrexate dosage: 2.5MG TABLETS AS 2 TABLETS PO. During the same period patient was treated with ACETAMINOPHEN, ASPIRIN, CHLORPHENIRAMINE MALEATE, CITALOPRAM HYDROBROMIDE, FOLIC ACID, FUROSEMIDE, IBUPROFEN, LORAZEPAM. Patient died.

Methotrexate Side Effects Report #4843044-8
Methotrexate side effect was reported by a Physician from GERMANY on Nov 16, 2005. Female patient, 56 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: accidental overdose, erysipelas, incorrect dose administered, pancytopenia, sepsis . Methotrexate dosage: 20 MG WEEKLY PO. Patient died.

Methotrexate Side Effects Report #4859854-7
Methotrexate side effect was reported by a Consumer or non-health professional from GERMANY on Dec 06, 2005. Female patient, 56 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: erysipelas, incorrect dose administered, mucosal inflammation, pancytopenia, sepsis . Methotrexate dosage: 20 MG WEEKLY, PO. Patient was hospitalized. Patient died on 01/01/1998.

Methotrexate Side Effects Report #4901996-1
Methotrexate side effect was reported by a Health Professional from GERMANY on Jan 23, 2006. Female patient, 56 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: erysipelas, mucosal inflammation, oral soft tissue disorder, overdose, pancytopenia, sepsis , skin lesion. Methotrexate dosage: unknown. Patient died.


Methotrexate Side Effects Report #4859857-2
Methotrexate side effect was reported by a Consumer or non-health professional from GERMANY on Dec 06, 2005. Female patient, 26 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: multi-organ failure, oral mucosa erosion, pancytopenia, pneumonia , prescribed overdose, sepsis . Methotrexate dosage: 15 MG/DAY X 6 DAYS, PO. Patient died on 01/01/2003.

Methotrexate Side Effects Report #5001071-4
Methotrexate side effect was reported by a Health Professional from TURKEY on May 01, 2006. Female patient, 22 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: calciphylaxis, sepsis . Methotrexate dosage: unknown. During the same period patient was treated with PREDNISOLONE. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #4596667-8
Methotrexate side effect was reported by a Consumer or non-health professional from on Dec 23, 2003. Male patient, 50 years of age, was diagnosed with psoriatic arthropathy and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: haemoptysis, herpes simplex , pancytopenia, pharyngolaryngeal pain, sepsis , staphylococcal infection . Methotrexate dosage: 7.5 MG WEEKLY PO. During the same period patient was treated with SULFASALAZINE, CLOPENTHIXOL. Patient recovered.

Methotrexate Side Effects Report #5525450-1
Methotrexate side effect was reported by a Physician from JAPAN on Nov 06, 2007. Female patient, 54 years of age, was diagnosed with prophylaxis against graft versus host disease, acute graft versus host disease, chronic myeloid leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: acute graft versus host disease in liver, cerebral toxoplasmosis, chronic myeloid leukaemia, leukaemia recurrent, pneumonia bacterial, sepsis . Methotrexate dosage: unknown. During the same period patient was treated with PREDNISOLONE, CYCLOPHOSPHAMIDE, IMATINIB, TRIMETHOPRIM, SULFAMETHOXAZOLE. Patient died.

Methotrexate Side Effects Report #5760127-9
Methotrexate side effect was reported by a Consumer or non-health professional from on May 30, 2008. Male patient, 30 years of age, was diagnosed with prophylaxis, acute lymphocytic leukaemia, evidence based treatment and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: csf immunoglobulin increased, csf protein increased, febrile neutropenia, pneumonia bacterial, radiculopathy, respiratory tract infection, sepsis , urinary incontinence , urinary retention. Methotrexate dosage: unknown. During the same period patient was treated with PREDNISONE, VINCRISTINE, DAUNORUBICIN, CYTARABINE, ELSPAR, HYDROCORTISONE, IMMUNE GLOBULIN INTRAVENOUS. Patient was hospitalized. Patient died.


Methotrexate Side Effects Report #5671314-2
Methotrexate side effect was reported by a Physician from UNITED STATES on Mar 04, 2008. Male patient, 76 years of age, was diagnosed with pemphigoid and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: lung infection pseudomonal, pancytopenia, pneumonia , sepsis . Methotrexate dosage: 2.5MG /TWICE WEEKLY/ORAL. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #5262373-X
Methotrexate side effect was reported by a Consumer or non-health professional from AUSTRALIA on Feb 21, 2007. Male patient, 25 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: bk virus infection, cerebral haemorrhage, cerebral infarction, haematuria, myelopathy, sepsis . Methotrexate dosage: unknown. During the same period patient was treated with CYTARABINE, CYCLOPHOSPHAMIDE, VINCRISTINE. Patient died.

Methotrexate Side Effects Report #5286053-X
Methotrexate side effect was reported by a Health Professional from AUSTRALIA on Apr 02, 2007. Male patient, 25 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: cerebral infarction, haemorrhage, sepsis , spinal cord disorder. Methotrexate dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, DOXORUBICIN, VINCRISTINE, DEXAMETHASONE, CYTARABINE, FLUDARABINE, IDARUBICIN, HEMATOPOETIC PROGENITOR CELLS. Patient died.

Methotrexate Side Effects Report #5292187-6
Methotrexate side effect was reported by a Health Professional from AUSTRALIA on Apr 09, 2007. Male patient, 25 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: cerebral infarction, haemorrhage, sepsis , spinal cord disorder. Methotrexate dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, DOXORUBICIN, VINCRISTINE, DEXAMETHASONE, CYTARABINE, FLUDARABINE, IDARUBICIN, HEMATOPOETIC PROGENITOR CELLS. Patient died.

Methotrexate Side Effects Report #5296486-3
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Apr 02, 2007. Male patient, 25 years of age, was diagnosed with non-hodgkin's lymphoma, prophylaxis and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: cerebral infarction, febrile neutropenia, haemorrhage, myelopathy, sepsis , spinal cord disorder. Methotrexate dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, DOXORUBICIN, VINCRISTINE, DEXAMETHASONE, CYTARABINE, FLUDARABINE, IDARUBICIN. Patient was hospitalized and became disabled. Patient died.


Methotrexate Side Effects Report #4635525-7
Methotrexate side effect was reported by a Health Professional from on Mar 29, 2005. Female patient, child 10 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: blood creatine increased, bone marrow depression, haemodialysis, multi-organ failure, sepsis . Methotrexate dosage: unknown. Patient died.

Methotrexate Side Effects Report #5348005-0
Methotrexate side effect was reported by a Health Professional from TAIWAN, PROVINCE OF CHINA on June 04, 2007. Female patient, 60 years of age, was diagnosed with lymphoma  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: sepsis , spinal cord disorder. Methotrexate dosage: unknown. During the same period patient was treated with HYDROCORTISONE, CYTARABINE. Patient died.

Methotrexate Side Effects Report #5009385-9
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on May 08, 2006. Female patient, child 11 years of age, was diagnosed with juvenile arthritis and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abscess , arthropod bite, erythema, necrotising fasciitis, sepsis , staphylococcal infection , tenderness. Methotrexate dosage: 25 MG WEEKLY, SC. During the same period patient was treated with ENBREL, PREDNISONE, NAPROXEN. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4686119-9
Methotrexate side effect was reported by a Physician from on Apr 28, 2005. Male patient, 65 years of age, was diagnosed with gastric cancer recurrent and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: ascites, depressed level of consciousness, ileus, intestinal obstruction, intestinal perforation, oliguria, sepsis , shock, white blood cell count decreased. Methotrexate dosage: 140 MG PER-CYCLE, IV. During the same period patient was treated with FLUOROURACIL. Patient recovered.

Methotrexate Side Effects Report #4635623-8
Methotrexate side effect was reported by a Consumer or non-health professional from on Mar 29, 2005. Female patient, 39 years of age, was diagnosed with fibrous histiocytoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: blood creatine increased, multi-organ failure, sepsis . Methotrexate dosage: unknown. During the same period patient was treated with LEUCOVORIN CALCIUM. Patient died.


Methotrexate Side Effects Report #5015470-8
Methotrexate side effect was reported by a Pharmacist from UNITED STATES on May 30, 2006. Male patient, 70 years of age, weighting 185.0 lb, was diagnosed with demyelinating polyneuropathy and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: dialysis , mucosal inflammation, pain of skin, pancytopenia, rash erythematous, renal failure, sepsis , treatment noncompliance. Methotrexate dosage: 7.5 MG - M-W-F (OUTPATIENT). Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5699381-0
Methotrexate side effect was reported by a Health Professional from UNITED STATES on Mar 26, 2008. Male patient, 61 years of age, was diagnosed with crohn's disease  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, acute respiratory failure, oral intake reduced, pneumonia , sepsis . Methotrexate dosage: unknown. Patient was hospitalized. Patient died on 09/27/2007.

Methotrexate Side Effects Report #5675682-7
Methotrexate side effect was reported by a Consumer or non-health professional from TAIWAN, PROVINCE OF CHINA on Mar 05, 2008. Female patient, 60 years of age, was diagnosed with central nervous system lymphoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: ill-defined disorder, muscular weakness, myelopathy, sensory disturbance, sepsis , spinal cord disorder, therapeutic agent toxicity, urinary incontinence , vibration test abnormal. Methotrexate dosage: 12 MG INTRATHECAL; 1 G/M2 INTRAVENOUS. During the same period patient was treated with CYTARABINE, HYDROCORTISONE. Patient died.

Methotrexate Side Effects Report #6035090-6
Methotrexate side effect was reported by a Consumer or non-health professional from on Jan 07, 2009. Male patient, 58 years of age, was diagnosed with central nervous system lymphoma, evidence based treatment and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: bone marrow failure, mucosal inflammation, pyrexia, renal failure acute, sepsis . Methotrexate dosage: unknown. During the same period patient was treated with PIPERACILLIN AND TAZOBACTAM, CPDG, CHARCOAL HAEMOPERFUSION, LEUCOVORIN CALCIUM. Patient died.

Methotrexate Side Effects Report #6055788-3
Methotrexate side effect was reported by a Physician from SPAIN on Jan 12, 2009. Male patient, 58 years of age, was diagnosed with central nervous system lymphoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: bone marrow failure, dialysis , mucosal inflammation, renal failure acute, sepsis . Methotrexate dosage: unknown. Patient was hospitalized. Patient died.


Methotrexate Side Effects Report #6115463-3
Methotrexate side effect was reported by a Physician from SPAIN on Mar 06, 2009. Male patient, 58 years of age, was diagnosed with central nervous system lymphoma, pyrexia, evidence based treatment and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: bone marrow failure, mucosal inflammation, pyrexia, renal failure acute, sepsis . Methotrexate dosage: unknown. During the same period patient was treated with PIPERACILLIN AND TAZOBACTAM, PIPERACILLIN AND TAZOBACTAM, LEUCOVORIN CALCIUM. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #6120626-7
Methotrexate side effect was reported by a Physician from SPAIN on Mar 06, 2009. Male patient, 58 years of age, was diagnosed with central nervous system lymphoma, pyrexia, evidence based treatment and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: bone marrow failure, mucosal inflammation, pyrexia, renal failure acute, sepsis . Methotrexate dosage: unknown. During the same period patient was treated with PIPERACILLIN AND TAZOBACTAM, PIPERACILLIN AND TAZOBACTAM, LEUCOVORIN CALCIUM. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #6120701-7
Methotrexate side effect was reported by a Physician from SPAIN on Mar 06, 2009. Male patient, 58 years of age, was diagnosed with central nervous system lymphoma, pyrexia, evidence based treatment and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: bone marrow failure, mucosal inflammation, pyrexia, renal failure acute, sepsis . Methotrexate dosage: unknown. During the same period patient was treated with PIPERACILLIN AND TAZOBACTAM, PIPERACILLIN AND TAZOBACTAM, LEUCOVORIN CALCIUM. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #5387416-4
Methotrexate side effect was reported by a Consumer or non-health professional from GERMANY on June 26, 2007. Male patient, 52 years of age, was diagnosed with central nervous system lymphoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: multi-organ failure, sepsis . Methotrexate dosage: unknown. Patient died.

Methotrexate Side Effects Report #5387417-6
Methotrexate side effect was reported by a Consumer or non-health professional from GERMANY on June 26, 2007. Female patient, 51 years of age, was diagnosed with central nervous system lymphoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: multi-organ failure, sepsis . Methotrexate dosage: unknown. Patient died.

Methotrexate Side Effects Report #4630158-0
Methotrexate side effect was reported by a Consumer or non-health professional from on Feb 22, 2005. Female patient was diagnosed with bone sarcoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: febrile neutropenia, sepsis . Methotrexate dosage: 2000 MG/M2. During the same period patient was treated with DOXORUBICIN, VINCRISTINE. Patient died.

Methotrexate Side Effects Report #5356120-0
Methotrexate side effect was reported by a Consumer or non-health professional from on June 06, 2007. Female patient, 60 years of age, was diagnosed with b-cell lymphoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: hypoaesthesia, muscular weakness, myelopathy, sensory loss, sepsis , urinary incontinence . Methotrexate dosage: 12 MG (9 SESSIONS). During the same period patient was treated with CYTARABINE, HYDROCORTISONE. Patient died on 03/01/2005.

Methotrexate Side Effects Report #4635543-9
Methotrexate side effect was reported by a Physician from on Mar 29, 2005. Female patient, child 5 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: bone marrow depression, bronchopulmonary aspergillosis, disease progression, haemorrhage, multi-organ failure, sepsis . Methotrexate dosage: unknown. During the same period patient was treated with LEUCOVORIN CALCIUM. Patient died.

Methotrexate Side Effects Report #4619404-7
Methotrexate side effect was reported by a Physician from on Oct 11, 2001. Female patient, child 4 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: multi-organ failure, sepsis , stevens-johnson syndrome. Methotrexate dosage: unknown. During the same period patient was treated with VINCRISTINE, DEXAMETHASONE. Patient was hospitalized. Patient died on 08/05/2001.

Methotrexate Side Effects Report #5826332-8
Methotrexate side effect was reported by a Consumer or non-health professional from SPAIN on July 17, 2008. Male patient, 30 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: febrile neutropenia, neurogenic bladder, pneumonia bacterial, radiculopathy, sepsis , urinary tract infection . Methotrexate dosage: 12 MG INTRATHECAL. During the same period patient was treated with HYDROCORTISONE, CYTOSINE ARABINOSIDE, VINCRISTINE, DAUNORUBICIN, PREDNISONE. Patient was hospitalized. Patient died.


Methotrexate Side Effects Report #5902587-6
Methotrexate side effect was reported by a Physician from SPAIN on Sept 11, 2008. Male patient, 30 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: febrile neutropenia, neurogenic bladder, pallanaesthesia, paraparesis, pneumonia bacterial, radiculopathy, respiratory tract infection, sepsis , urinary tract infection . Methotrexate dosage: unknown. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #5286154-6
Methotrexate side effect was reported by a Health Professional from AUSTRALIA on Apr 02, 2007. Female patient, 26 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: atrophy, leukaemia recurrent, malignant neoplasm progression, myelopathy, osteomyelitis, sepsis , spinal cord disorder. Methotrexate dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, VINCRISTINE SULPHATE, DOXORUBICIN, DEXAMETHASONE, CYTARABINE, MERCAPTOPURINE. Patient died.

Methotrexate Side Effects Report #5292239-0
Methotrexate side effect was reported by a Health Professional from AUSTRALIA on Apr 09, 2007. Female patient, 26 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: malignant neoplasm progression, osteomyelitis, sepsis , spinal cord disorder. Methotrexate dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, VINCRISTINE SULPHATE, DOXORUBICIN, DEXAMETHASONE, CYTARABINE, MERCAPTOPURINE. Patient died.

Methotrexate Side Effects Report #5293624-3
Methotrexate side effect was reported by a Consumer or non-health professional from on Apr 05, 2007. Female patient, 26 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: incontinence, leukaemia recurrent, myelopathy, osteomyelitis, paralysis flaccid, sensory loss, sepsis . Methotrexate dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, DEXAMETHASONE, MERCAPTOPURINE, VINCRISTINE, DOXORUBICIN, CYTARABINE, ANTIVIRAL TREATMENT, STEROID TREATMENT. Patient died.

Methotrexate Side Effects Report #5296489-9
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Apr 02, 2007. Female patient, 26 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: malignant neoplasm progression, myelopathy, osteomyelitis, sepsis , spinal cord disorder. Methotrexate dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, VINCRISTINE SULPHATE, DOXORUBICIN, DEXAMETHASONE, CYTARABINE, MERCAPTOPURINE. Patient was hospitalized and became disabled. Patient died.

Methotrexate Side Effects Report #4955274-5
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Mar 10, 2006. Male patient, 15 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: blood osmolarity increased, hypotension, polyuria, sepsis . Methotrexate dosage: 5000 MG/M2 X FOUR COURSES (NR), IT. During the same period patient was treated with MERCAPTOPURINE, VINCRISTINE, PREDNISONE, DAUNORUBICIN, CYTARABINE, ELSPAR, HYDROCORTISONE. Patient recovered.

Methotrexate Side Effects Report #4661076-X
Methotrexate side effect was reported by a Consumer or non-health professional from on Apr 26, 2005. Male patient, 87 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: non-hodgkin's lymphoma, pneumonia , radiation injury, sepsis . Methotrexate dosage: unknown. Patient died.

Methotrexate Side Effects Report #4773778-5
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Sept 02, 2005. Female patient, 84 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: melaena, mucosal inflammation, pancytopenia, sepsis . Methotrexate dosage: 10 MG WEEKLY PO. During the same period patient was treated with ASPIRIN, CELECOXIB, LANSOPRAZOLE, DIGOXIN, CEPHRADINE, AMOXICILLIN. Patient died.

Methotrexate Side Effects Report #5012301-7
Methotrexate side effect was reported by a Physician from UNITED KINGDOM on May 17, 2006. Female patient, 84 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: melaena, mucosal inflammation, pancytopenia, sepsis . Methotrexate dosage: 10 MG PER WEEK, PO. During the same period patient was treated with ASPIRIN, CELECOXIB, LANSOPRAZOLE, DIGOXIN, CEPHRADINE, AMOXICILLIN. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #4877311-9
Methotrexate side effect was reported by a Consumer or non-health professional from on Dec 27, 2005. Female patient, 82 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: pancytopenia, sepsis . Methotrexate dosage: 10 MG PER WEEK, PO. During the same period patient was treated with PREDNISOLONE, CELECOXIB, ALENDRONATE, LISINOPRIL, BENDROFLUAZIDE. Patient was hospitalized. Patient recovered.


Methotrexate Side Effects Report #4877327-2
Methotrexate side effect was reported by a Consumer or non-health professional from on Jan 09, 2006. Female patient, 82 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: pancytopenia, pneumonia , sepsis . Methotrexate dosage: 10 MG PER WEEK, SC. During the same period patient was treated with PERINDOPRIL, FUROSEMIDE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5011473-8
Methotrexate side effect was reported by a Consumer or non-health professional from on May 17, 2006. Female patient, 82 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: pancytopenia, pneumonia , sepsis . Methotrexate dosage: 10 MG PER WEEK, SC. During the same period patient was treated with PERINDOPRIL ERUMINE, FUROSEMIDE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5011975-4
Methotrexate side effect was reported by a Consumer or non-health professional from on May 17, 2006. Female patient, 82 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: pancytopenia, sepsis . Methotrexate dosage: 10 MG PER WEEK, PO. During the same period patient was treated with PREDNISOLONE, CELECOXIB, ALENDRONATE, LISINOPRIL, BENDROFLUAZIDE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4877434-4
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Dec 27, 2005. Female patient, 81 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: dyspnoea, mucosal inflammation, pancytopenia, sepsis . Methotrexate dosage: 25 MG PER WEEK , PO. During the same period patient was treated with CARBIMAZOLE, CELECOXIB, FOLIC ACID, OMEPRAZOLE, ALENDRONATE. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #5012299-1
Methotrexate side effect was reported by a Physician from UNITED KINGDOM on May 17, 2006. Female patient, 81 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: dyspnoea, mucosal inflammation, pancytopenia, sepsis . Methotrexate dosage: 25 MG PER WEEK, PO. During the same period patient was treated with CARBIMAZOLE, CELECOXIB, FOLIC ACID, OMEPRAZOLE, ALENDRONATE. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #4773777-3
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Sept 02, 2005. Female patient, 77 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: pancytopenia, sepsis . Methotrexate dosage: 7.5 MG WEEKLY PO. During the same period patient was treated with ACETAMINOPHEN W, TEMAZEPAM, THYROXINE, FOLIC ACID. Patient died.

Methotrexate Side Effects Report #4877297-7
Methotrexate side effect was reported by a Consumer or non-health professional from on Dec 27, 2005. Female patient, 77 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: pancytopenia, sepsis . Methotrexate dosage: 7.5 MG PER WEEK (NR, 1 IN 1 WK), PO. During the same period patient was treated with LEVOTHYROXINE, FOLIC ACID, FLUOXETINE, FUROSEMIDE, TEMAZEPAM. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #5012083-9
Methotrexate side effect was reported by a Physician from UNITED KINGDOM on May 17, 2006. Female patient, 77 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: pancytopenia, sepsis . Methotrexate dosage: 7.5 MG PER WEEK (1 IN 1 WK), PO. During the same period patient was treated with LEVOTHYROXINE, FOLIC ACID, FLUOXETINE, FUROSEMIDE, TEMAZEPAM. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #4622966-7
Methotrexate side effect was reported by a Consumer or non-health professional from on Nov 25, 2003. Female patient, 74 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: bone marrow depression, sepsis . Methotrexate dosage: 4 MG WEEKLY. Patient died.

Methotrexate Side Effects Report #4877302-8
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Dec 27, 2005. Female patient, 74 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: mucosal inflammation, pancytopenia, sepsis . Methotrexate dosage: unknown. During the same period patient was treated with LEVOTHYROXINE, PREDNISOLONE, OXYTETRACYCLINE, FUSIDIC ACID. Patient was hospitalized. Patient died.


Methotrexate Side Effects Report #4877287-4
Methotrexate side effect was reported by a Consumer or non-health professional from on Dec 27, 2005. Female patient, 73 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: cardiac failure, pancytopenia, pneumonia , sepsis . Methotrexate dosage: 7.5 MG PER WEEK (NR, 1 IN 1 WK), PO. During the same period patient was treated with LANSOPRAZOLE, AMITRIPTYLINE, CELECOXIB, LEVOTHYROXINE, OXYBUTININ, COPROXAMAL. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5012069-4
Methotrexate side effect was reported by a Physician from UNITED KINGDOM on May 17, 2006. Female patient, 73 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: cardiac failure, pancytopenia, pneumonia , sepsis . Methotrexate dosage: 7.5 MG PER WEEK (1 IN 1 WK), PO. During the same period patient was treated with LANSOPRAZOLE, AMITRIPTYLINE, CELECOXIB, LEVOTHYROXINE, OXYBUTININ, COPROXAMOL. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4877277-1
Methotrexate side effect was reported by a Consumer or non-health professional from on Dec 27, 2005. Male patient, 71 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: gingival bleeding, melaena, mucosal inflammation, pancytopenia, sepsis . Methotrexate dosage: 10 MG PER WEEK (NR, 1 IN 1 WK), PO. During the same period patient was treated with PREDNISOLONE, GLIPIZIDE, FELODIPINE, BISOPROLOL, DIGOXIN, WARFARIN, LISINOPRIL. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #5012025-6
Methotrexate side effect was reported by a Physician from UNITED KINGDOM on May 17, 2006. Male patient, 71 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: gingival bleeding, melaena, mucosal inflammation, pancytopenia, sepsis . Methotrexate dosage: 10 MG PER WEEK (1 IN 1 WK), PO. During the same period patient was treated with PREDNISOLONE, GLIPIZIDE, FELODIPINE, BISOPROLOL FUMARATE, DIGOXIN, WARFARIN, LISINORPIL. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #4877334-X
Methotrexate side effect was reported by a Consumer or non-health professional from on Dec 27, 2005. Male patient, 69 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: epistaxis, mucosal inflammation, pancytopenia, sepsis . Methotrexate dosage: 12.5 MG PER WEEK, PO. During the same period patient was treated with FOLIC ACID, BACTRIM, PREDNISOLONE, RISEDRONATE, ATENOLOL, FELODIPINE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5011445-3
Methotrexate side effect was reported by a Consumer or non-health professional from on May 17, 2006. Male patient, 69 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: epistaxis, mucosal inflammation, pancytopenia, sepsis . Methotrexate dosage: 12.5 MG PER WEEK, PO. During the same period patient was treated with FOLIC ACID, BACTRIM, PREDNISOLONE, RISEDRONATE, ATENOLOL, FELODIPINE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5052814-5
Methotrexate side effect was reported by a Pharmacist from UNITED STATES on July 13, 2006. Female patient, 63 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: acute myocardial infarction, cardio-respiratory arrest, hypoaesthesia, hypotension, renal failure acute, sepsis , ventricular tachycardia. Methotrexate dosage: unknown. Patient died on 06/13/2006.

Methotrexate Side Effects Report #4877436-8
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Dec 27, 2005. Female patient, 61 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: epistaxis, haematuria, mucosal inflammation, pancytopenia, sepsis . Methotrexate dosage: 25 MG PER WEEK, PO. During the same period patient was treated with FOLIC ACID, PREDNISOLONE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5012302-9
Methotrexate side effect was reported by a Physician from UNITED KINGDOM on May 17, 2006. Female patient, 61 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: blood albumin decreased, epistaxis, haematuria, mucosal inflammation, pancytopenia, renal impairment, sepsis . Methotrexate dosage: 25 MG PER WEEK, PO. During the same period patient was treated with FOLIC ACID, PREDNISOLONE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5677604-1
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Mar 04, 2008. Female patient, 60 years of age, weighting 176.4 lb, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: beta haemolytic streptococcal infection, continuous haemodiafiltration, multi-organ failure, sepsis . Methotrexate dosage: 7.5 MG WEEKLY. During the same period patient was treated with ENBREL, PREDNISOLONE, ASPIRIN, ATENOLOL, FUROSEMIDE, GLICLAZIDE, MELOXICAM, OMEPRAZOLE. Patient recovered.


Methotrexate Side Effects Report #4550116-4
Methotrexate side effect was reported by a Consumer or non-health professional from on Nov 11, 2004. Female patient, 53 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, asthenia, hypotension, lobar pneumonia, pharyngolaryngeal pain, respiratory failure, sepsis , vomiting. Methotrexate dosage: 15 MG WEEKLY SC. During the same period patient was treated with PREDNISONE, ENBREL, FOLIC ACID, PEPCID, ACTONEL, PILCARPINE HDYROCHLORIDE, INSULIN GLARGINE, INSULIN ASPART. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4621864-2
Methotrexate side effect was reported by a Consumer or non-health professional from on Feb 03, 2004. Female patient, 46 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: cardiomyopathy , mastoiditis, meningitis pneumococcal, sepsis . Methotrexate dosage: unknown. During the same period patient was treated with ETANERCEPT. Patient recovered.

Methotrexate Side Effects Report #5262363-7
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Feb 20, 2007. Female patient, 40 years of age, weighting 127.9 lb, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: beta haemolytic streptococcal infection, brain abscess, cerebral infarction, intervertebral discitis, psoas abscess, sepsis . Methotrexate dosage: unknown. During the same period patient was treated with REMICADE, ADCAL, FOLIC ACID, ACETAMINOPHEN, RISEDRONATE, SANDOCAL, SULFASALAZINE, VOLTAREN. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4785412-9
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Sept 15, 2005. Female patient, 27 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: cough, malaise, nasopharyngitis, pharyngolaryngeal pain, sepsis . Methotrexate dosage: unknown. During the same period patient was treated with ENBREL. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4933529-8
Methotrexate side effect was reported by a Consumer or non-health professional from JAPAN on Feb 22, 2006. Male patient, 15 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: cytomegalovirus enterocolitis, diarrhoea, graft versus host disease, herpes zoster, interstitial lung disease, performance status decreased, sepsis , weight decreased. Methotrexate dosage: unknown. During the same period patient was treated with NEORAL. Patient recovered.

Methotrexate Side Effects Report #4957747-8
Methotrexate side effect was reported by a Consumer or non-health professional from JAPAN on Feb 22, 2006. Male patient, 15 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: acute lymphocytic leukaemia recurrent, graft versus host disease, herpes zoster, interstitial lung disease, sepsis . Methotrexate dosage: unknown. During the same period patient was treated with SANDIMMUNE, IRRADIATION, CYCLOPHOSPHAMIDE, VEPESID. Patient recovered.

Methotrexate Side Effects Report #4619407-2
Methotrexate side effect was reported by a Physician from on Oct 11, 2004. Female patient, 13 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: sepsis , stevens-johnson syndrome. Methotrexate dosage: unknown. During the same period patient was treated with VINCRISTINE, DEXAMETHASONE. Patient was hospitalized. Patient died on 08/06/2001.