Methotrexate and respiratory failure Patient Reports February 11, 2012

Methotrexate Side Effects Report #4591574-9
Methotrexate side effect was reported by a Health Professional from on Feb 15, 2005. Male patient was diagnosed with sarcoidosis and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: hepatic function abnormal, organ failure, pneumonitis, respiratory failure. Methotrexate dosage: 12.50 MG, WEEKLY,. During the same period patient was treated with FOLACIN, ERYTHROMYCIN STEARATE, PREDNISONE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4919997-6
Methotrexate side effect was reported by a Consumer or non-health professional from GERMANY on Feb 03, 2006. Female patient, 85 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: accidental overdose, pancytopenia, respiratory failure, septic shock. Methotrexate dosage: 20 MG DAILY. During the same period patient was treated with XIPAMIDE, NITRATES. Patient died.

Methotrexate Side Effects Report #5473637-9
Methotrexate side effect was reported by a Consumer or non-health professional from on Sept 24, 2007. Male patient, 78 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: coccidioidomycosis, dyspnoea, night sweats, normochromic normocytic anaemia, productive cough, pyrexia, respiratory failure, skin lesion, weight decreased. Methotrexate dosage: unknown. During the same period patient was treated with INFLIXIMAB. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #4596638-1
Methotrexate side effect was reported by a Consumer or non-health professional from on Jan 27, 2004. Female patient, 78 years of age, was diagnosed with rheumatoid arthritis , swelling, depression  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: melaena, mucosal inflammation, pancytopenia, pleural effusion, respiratory failure. Methotrexate dosage: 25 MG WEEKLY. During the same period patient was treated with FRUSEMIDE, POTASSIUM CHLORIDE, RANITIDINE, ACETYLSALICYLIC ACID SRT, DOXEPIN. Patient was hospitalized. Patient recovered.


Methotrexate Side Effects Report #4514173-3
Methotrexate side effect was reported by a Consumer or non-health professional from on Nov 15, 2004. Female patient, 77 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: immunosuppression, infection , interstitial lung disease, multi-organ failure, respiratory failure, septic shock. Methotrexate dosage: 20 MG 1X PER 1 WK, ORAL. During the same period patient was treated with ENBREL. Patient was hospitalized. Patient died on 10/30/2004.

Methotrexate Side Effects Report #5521262-3
Methotrexate side effect was reported by a Consumer or non-health professional from on Nov 14, 2007. Female patient, 76 years of age, was diagnosed with rheumatoid arthritis , bacterial infection , pneumocystis jiroveci pneumonia, hypogammaglobulinaemia, herpes virus infection and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: bacterial infection , blister, duodenal ulcer, herpes virus infection, hypogammaglobulinaemia, pneumocystis jiroveci pneumonia, respiratory failure, skin ulcer. Methotrexate dosage: unknown. During the same period patient was treated with PREDNISOLONE, LEVOFLOXACIN, SULFAMETHOXAZOLE, IMMUNE GLOBULIN INTRAVENOUS, ACYCLOVIR. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5167479-1
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Nov 16, 2006. Female patient, 75 years of age, weighting 171.1 lb, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: mycobacterium avium complex infection, pulmonary fibrosis , respiratory failure. Methotrexate dosage: unknown. During the same period patient was treated with REMICADE, ADCAL, CLARITHROMYCIN, ETHAMBUTOL HYDROCHLORIDE, MS CONTIN, PREDNISOLONE, RIFAMPICIN, STREPTOMYCIN. Patient died.

Methotrexate Side Effects Report #4557840-8
Methotrexate side effect was reported by a Health Professional from on Jan 04, 2005. Female patient, 73 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: diarrhoea, haemodialysis, multi-organ failure, platelet count decreased, pneumonia , pyelonephritis, renal failure, respiratory failure, septic shock. Methotrexate dosage: 12.5 MG WEEKLY. During the same period patient was treated with SIMVASTATIN, FOLIC ACID, AMLODIPINE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5127558-1
Methotrexate side effect was reported by a Physician from JAPAN on Sept 22, 2006. Female patient, 68 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, pneumocystis jiroveci pneumonia, respiratory failure. Methotrexate dosage: 5 MG QW. During the same period patient was treated with PREDNISOLONE, DICLOFENAC, BUCILLAMINE. Patient was hospitalized. Patient recovered.


Methotrexate Side Effects Report #4594789-9
Methotrexate side effect was reported by a Consumer or non-health professional from on Feb 08, 2005. Male patient, 66 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alveolitis, pulmonary fibrosis , respiratory arrest, respiratory failure. Methotrexate dosage: 10 MG WEEKLY. During the same period patient was treated with LEFLUNOMIDE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5055462-6
Methotrexate side effect was reported by a Health Professional from PERU on July 11, 2006. Male patient, 64 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: pneumocystis jiroveci pneumonia, respiratory failure. Methotrexate dosage: 15 MG - 1XW - ORAL. During the same period patient was treated with ORENCIA, REMICADE, PREDNISONE, IBUPROFEN, RANITIDINE, CAPTOPRIL, CALCIUM CARBONATE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4726343-X
Methotrexate side effect was reported by a Health Professional from FRANCE on July 18, 2005. Male patient, 64 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: nosocomial infection, pneumocystis jiroveci pneumonia, respiratory failure. Methotrexate dosage: 15 MG - 1XW; ORAL. During the same period patient was treated with ABATACEPT, INFLIXIMAB, PREDNISONE, IBUPROFEN, RANITIDINE, CAPTOPRIL, CALCIUM CARBONATE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4757727-1
Methotrexate side effect was reported by a Health Professional from PERU on Aug 22, 2005. Male patient, 64 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: pneumocystis jiroveci pneumonia, respiratory failure. Methotrexate dosage: 15 MG - 1XW - ORAL. During the same period patient was treated with ABATACEPT, INFLIXIMAB, PREDNISONE, IBUPROFEN, RANITIDINE, CAPTOPRIL, CALCIUM CARBONATE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4930948-0
Methotrexate side effect was reported by a Health Professional from PERU on Feb 21, 2006. Male patient, 64 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: pneumocystis jiroveci pneumonia, respiratory failure. Methotrexate dosage: 15 MG 1XW ORAL. During the same period patient was treated with ABATACEPT, PREDNISONE, IBUPROFEN, RANITIDINE, CAPTOPRIL, CALCIUM CARBONATE, FOLIC ACID. Patient was hospitalized. Patient recovered.


Methotrexate Side Effects Report #6128264-7
Methotrexate side effect was reported by a Health Professional from UNITED KINGDOM on Mar 04, 2009. Female patient, 63 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: chest discomfort, chest pain , cough, haemoglobin decreased, infection , oxygen saturation decreased, pneumonitis, respiratory failure, rib fracture. Methotrexate dosage: unknown. During the same period patient was treated with IBUPROFEN, PREDNISOLONE, TRAMADOL. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4596775-1
Methotrexate side effect was reported by a Consumer or non-health professional from on June 23, 2004. Female patient, 63 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: dyspnoea, productive cough, respiratory failure, respiratory tract infection. Methotrexate dosage: unknown. During the same period patient was treated with ETANERCEPT, PREDNISOLONE, ALENDRONATE, CELECOXIB, RAMIPRIL. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #5825781-1
Methotrexate side effect was reported by a Pharmacist from UNITED STATES on July 28, 2008. Male patient, 62 years of age, weighting 175.0 lb, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: cough, respiratory failure. Methotrexate dosage: 15MG WEEKLY PO. During the same period patient was treated with PREDNISONE, TYLENOL. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4596576-4
Methotrexate side effect was reported by a Consumer or non-health professional from on July 30, 2004. Male patient, 60 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: myocarditis, pancytopenia, respiratory failure. Methotrexate dosage: unknown. During the same period patient was treated with FOLIC ACID, MELOXICAM. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #4596627-7
Methotrexate side effect was reported by a Consumer or non-health professional from on Mar 24, 2004. Female patient, 58 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: nausea , respiratory failure, salivary hypersecretion. Methotrexate dosage: 10 MG WEEKLY, IM. Patient recovered.


Methotrexate Side Effects Report #5832431-7
Methotrexate side effect was reported by a Physician from GERMANY on July 21, 2008. Male patient, 53 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: acinetobacter infection, bronchoalveolar lavage abnormal, dizziness , herpes simplex dna test positive, multi-organ failure, oropharyngeal candidiasis, pneumocystis jiroveci pneumonia, respiratory failure, sepsis . Methotrexate dosage: 20 MG, QW, SUBCUTANEOUS. During the same period patient was treated with PREDNISOLONE, LEFLUNOMIDE. Patient died.

Methotrexate Side Effects Report #4576364-5
Methotrexate side effect was reported by a Consumer or non-health professional from on Dec 10, 2004. Male patient, 59 years of age, was diagnosed with parkinson's disease  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, infection , lung disorder, pneumonitis, pseudomonas infection, pulmonary fibrosis , respiratory failure. Methotrexate dosage: 800 - 1000 MG. During the same period patient was treated with AMANTADINE, SINEMET. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #5300771-6
Methotrexate side effect was reported by a Health Professional from MALAYSIA on Apr 16, 2007. Male patient, 40 years of age, was diagnosed with hodgkin's disease  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: myelopathy, respiratory failure, somnolence. Methotrexate dosage: unknown. During the same period patient was treated with DOXORUBICIN, BLEOMYCIN, CYCLOPHOSPHAMIDE, VINCRISTINE SULPHATE. Patient died on 06/16/2005.

Methotrexate Side Effects Report #4660547-X
Methotrexate side effect was reported by a Health Professional from on May 02, 2005. Female patient, 33 years of age, was diagnosed with gestational trophoblastic tumour and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: pneumocystis jiroveci pneumonia, respiratory failure. Methotrexate dosage: unknown. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4692323-6
Methotrexate side effect was reported by a Consumer or non-health professional from on June 01, 2005. Male patient, 71 years of age, was diagnosed with chronic lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: chest pain , dyspnoea, pneumonia , pulmonary embolism , pyrexia, respiratory failure. Methotrexate dosage: unknown. During the same period patient was treated with CYTARABINE, CORTICOSTERIODS. Patient died.


Methotrexate Side Effects Report #5389710-X
Methotrexate side effect was reported by a Consumer or non-health professional from on July 13, 2007. Female patient, 21 years of age, was diagnosed with choriocarcinoma, hyperthyroidism and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: anaemia, hypoxia, lung infiltration, pulmonary haemorrhage, respiratory acidosis, respiratory disorder, respiratory failure, tachycardia. Methotrexate dosage: unknown. During the same period patient was treated with PROPYLTHIOURACIL, INDERAL. Patient died.

Methotrexate Side Effects Report #5402061-X
Methotrexate side effect was reported by a Health Professional from UNITED STATES on July 17, 2007. Female patient, 21 years of age, was diagnosed with choriocarcinoma, metastasis and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: anaemia, hypoxia, lung infiltration, pulmonary haemorrhage, respiratory acidosis, respiratory failure, tachycardia, tumour lysis syndrome. Methotrexate dosage: 1 MG/IM/T X 1. During the same period patient was treated with METHOTREXATE USP. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #5416529-3
Methotrexate side effect was reported by a Physician from SAUDI ARABIA on July 06, 2007. Female patient, 21 years of age, weighting 121.3 lb, was diagnosed with choriocarcinoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: anaemia, lung disorder, lung infiltration, pulmonary haemorrhage, respiratory acidosis, respiratory failure, tachycardia, tumour lysis syndrome. Methotrexate dosage: 1 MG/KG (55 MG), ONCE, IM. During the same period patient was treated with PROPYLTHIOURACIL, INDERAL. Patient died on 01/01/2007.

Methotrexate Side Effects Report #4629384-6
Methotrexate side effect was reported by a Consumer or non-health professional from on Mar 03, 2005. Female patient, child 10 years of age, was diagnosed with burkitt's lymphoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: cardiac failure, coma, renal failure, respiratory distress, respiratory failure. Methotrexate dosage: 15 MG PER_CYCLE. During the same period patient was treated with VINCRISTINE, CYCLOPHOSPHAMIDE, PREDNISOLONE, HYDROCORTISONE. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #4831468-4
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Nov 14, 2005. Male patient, 61 years of age, weighting 246.9 lb, was diagnosed with arthritis , prophylaxis and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: infection , interstitial lung disease, pneumonia , pulmonary fibrosis , respiratory failure, stomatitis. Methotrexate dosage: 2.5 MG, 4 TIMES/WEEK (2.5 MG), PO 3 TO 4 YEARS. During the same period patient was treated with FOLIC ACID, PREDNISONE, CELEBREX, CALCIUM, VITAMIN. Patient was hospitalized. Patient died on 09/06/2005.


Methotrexate Side Effects Report #4704098-2
Methotrexate side effect was reported by a Consumer or non-health professional from on May 31, 2005. Female patient, 17 years of age, was diagnosed with acute lymphocytic leukaemia recurrent and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, bone marrow depression, emphysema, escherichia sepsis, pneumonia , pulmonary mycosis, respiratory failure, systemic candida. Methotrexate dosage: 12 MG IT. During the same period patient was treated with CYTARABINE, HYDROCORTISONE SUCCINATE. Patient recovered.

Methotrexate Side Effects Report #4594037-X
Methotrexate side effect was reported by a Physician from on Feb 02, 2005. Male patient, child 7 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: cardiac failure, febrile neutropenia, mucosal inflammation, prescribed overdose, respiratory failure. Methotrexate dosage: unknown. During the same period patient was treated with CYTARABINE, DAUNORUBICIN, VINCRISTINE, ASPARAGINASE, CYCLOPHOSPHAMIDE, MERCAPTOPURINE, PREDNISONE. Patient recovered.

Methotrexate Side Effects Report #4616814-9
Methotrexate side effect was reported by a Consumer or non-health professional from on Feb 02, 2005. Male patient, child 7 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: cardiac failure, febrile neutropenia, mucosal inflammation, respiratory failure. Methotrexate dosage: unknown. During the same period patient was treated with CYTARABINE, DAUNORUBICIN, VINCRISTINE, ASPARAGINASE, CYCLOPHOSPHAMIDE, MERCAPTOPURINE, PREDNISONE, DEXAMETHASONE. Patient recovered.

Methotrexate Side Effects Report #4966496-1
Methotrexate side effect was reported by a Health Professional from GERMANY on Mar 27, 2006. Female patient, 85 years of age, was diagnosed with cardiac failure and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: erythema, mucosal inflammation, overdose, pancytopenia, respiratory failure, septic shock, stridor. Methotrexate dosage: unknown. During the same period patient was treated with XIPAMIDE, NITRATES. Patient died.

Methotrexate Side Effects Report #5385339-8
Methotrexate side effect was reported by a Pharmacist from UNITED STATES on July 09, 2007. Female patient, 81 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: mouth haemorrhage, mucosal inflammation, respiratory failure, urosepsis, white blood cell count decreased. Methotrexate dosage: unknown. Patient died.


Methotrexate Side Effects Report #4607508-4
Methotrexate side effect was reported by a Consumer or non-health professional from on Feb 21, 2005. Male patient, 75 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alveolitis, respiratory failure. Methotrexate dosage: 10 MG WEEKLY. During the same period patient was treated with OMEPRAZOLE, DICLOFENAC, FOLIC ACID, PREDNISOLONE, ATORVASTATIN CALCIUM, PERINDOPRIL. Patient died.

Methotrexate Side Effects Report #5862429-4
Methotrexate side effect was reported by a Consumer or non-health professional from JAPAN on Aug 14, 2008. Male patient, 71 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: angiocentric lymphoma, diffuse alveolar damage, interstitial lung disease, respiratory failure. Methotrexate dosage: 6 MG/WEEK, 8 MG/WEEK. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #5684485-9
Methotrexate side effect was reported by a Physician from FRANCE on Mar 21, 2008. Male patient, 58 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: cardiac failure, dilatation ventricular, ejection fraction decreased, hypertrophic cardiomyopathy, left atrial dilatation, pericardial effusion, pulmonary hypertension , respiratory failure. Methotrexate dosage: unknown. During the same period patient was treated with ARACYTINE, DEXAMETHASONE, VINCRISTINE, DOXORUBICIN, ENDOXAN, NEULASTA, ALLOPURINOL, NEXIUM. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4550116-4
Methotrexate side effect was reported by a Consumer or non-health professional from on Nov 11, 2004. Female patient, 53 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, asthenia, hypotension, lobar pneumonia, pharyngolaryngeal pain, respiratory failure, sepsis , vomiting. Methotrexate dosage: 15 MG WEEKLY SC. During the same period patient was treated with PREDNISONE, ENBREL, FOLIC ACID, PEPCID, ACTONEL, PILCARPINE HDYROCHLORIDE, INSULIN GLARGINE, INSULIN ASPART. Patient was hospitalized. Patient recovered.