Methotrexate and haemoglobin decreased Patient Reports February 11, 2012

Methotrexate Side Effects Report #6099532-2
Methotrexate side effect was reported by a Physician from JAPAN on Feb 12, 2009. Female patient, 73 years of age, was diagnosed with sjogren's syndrome , systemic lupus erythematosus and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, epistaxis, haemoglobin decreased, metastases to bone, metastases to lymph nodes, neuroendocrine carcinoma of the skin, thrombocytopenia. Methotrexate dosage: 6 MG/WK. During the same period patient was treated with PREDNISOLONE. Patient died.

Methotrexate Side Effects Report #4757224-3
Methotrexate side effect was reported by a Consumer or non-health professional from on Aug 16, 2005. Female patient, 83 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: acute myeloid leukaemia, haemoglobin decreased. Methotrexate dosage: 5 MG/WEEK (1 IN 1 WK). During the same period patient was treated with INDOMETHACIN, DETROPROPOXYPHEN. Patient died on 01/01/1991.

Methotrexate Side Effects Report #4845367-5
Methotrexate side effect was reported by a Consumer or non-health professional from JAPAN on Nov 09, 2005. Male patient, 75 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: blood albumin decreased, blood alkaline phosphatase increased, blood lactate dehydrogenase increased, blood pressure increased, blood urea increased, haemoglobin decreased, joint dislocation, joint swelling. Methotrexate dosage: unknown. During the same period patient was treated with SULFASALAZINE. Patient recovered.

Methotrexate Side Effects Report #5117836-4
Methotrexate side effect was reported by a Health Professional from UNITED KINGDOM on Sept 21, 2006. Female patient, 73 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: haemoglobin decreased, herpes zoster, mouth ulceration, petechiae, platelet count decreased, white blood cell count decreased. Methotrexate dosage: 7.5 MG PO QD. During the same period patient was treated with PREDNISOLONE, FOLIC ACID, MORPHINE SULPHATE, ROFECOXIB, NITRAZEPAM. Patient was hospitalized. Patient died on 07/04/2004.


Methotrexate Side Effects Report #5166813-6
Methotrexate side effect was reported by a Health Professional from UNITED KINGDOM on Nov 22, 2006. Female patient, 73 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: haemoglobin decreased, herpes zoster, mouth ulceration, petechiae, platelet count decreased, white blood cell count decreased. Methotrexate dosage: 7.5 MG PO QD. During the same period patient was treated with PREDNISOLONE, FOLIC ACID, MORPHINE SULPHATE, ROFECOXIB, NITRAZEPAM. Patient was hospitalized. Patient died on 07/04/2004.

Methotrexate Side Effects Report #4699569-1
Methotrexate side effect was reported by a Consumer or non-health professional from on June 07, 2005. Female patient, 73 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: faecal occult blood positive, haemoglobin decreased, intestinal adenocarcinoma. Methotrexate dosage: 15 MG, IM. During the same period patient was treated with INFLIXIMAB, METHYPRESNISOLONE, FOLIC ACID, CALCIUM CARBONATE, CLASTEON, SULINDAC, PYRIDOXINE, SALMETEROL. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5613410-1
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Jan 16, 2008. Male patient, 71 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: angiocentric lymphoma, blood lactate dehydrogenase increased, c-reactive protein increased, diffuse alveolar damage, dyspnoea, epstein-barr virus antibody positive, haemoglobin decreased, hypoxia, interstitial lung disease. Methotrexate dosage: 8MG/WK. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #5847437-1
Methotrexate side effect was reported by a Consumer or non-health professional from JAPAN on July 31, 2008. Male patient, 71 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: angiocentric lymphoma, blood immunoglobulin e increased, blood lactate dehydrogenase increased, diffuse alveolar damage, epstein-barr virus infection, haemoglobin decreased, hypoxia, interstitial lung disease, lymphocyte stimulation test positive. Methotrexate dosage: 6 MG/WEEK; 8 MG/WEEK. Patient died.

Methotrexate Side Effects Report #4902369-8
Methotrexate side effect was reported by a Physician from JAPAN on Jan 23, 2006. Male patient, 70 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: antinuclear antibody positive, epstein-barr virus antigen positive, haematocrit decreased, haemoglobin decreased, non-hodgkin's lymphoma, red blood cell count decreased, rheumatoid factor increased, septic shock. Methotrexate dosage: 6 MG WEEKLY. Patient recovered.


Methotrexate Side Effects Report #4572233-5
Methotrexate side effect was reported by a Physician from on Jan 19, 2005. Female patient, 68 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: cardiac tamponade, coma, haemoglobin decreased, loss of consciousness, pericardial haemorrhage, shock, thrombosis. Methotrexate dosage: unknown. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4733395-X
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on July 18, 2005. Female patient, 66 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: blood folate decreased, colour vision tests abnormal, haemoglobin decreased, optic neuropathy, scotoma, visual acuity tests abnormal, visual field defect. Methotrexate dosage: 2.5 MG 3/WK, PO. Patient recovered.

Methotrexate Side Effects Report #4750072-X
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Aug 04, 2005. Female patient, 66 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: blood folate decreased, haemoglobin decreased, laboratory test abnormal, mean cell volume increased, scotoma, visual evoked potentials abnormal. Methotrexate dosage: 2.5 MG (THREE TIME PER WEEK (2.5 MG, 3 IN 1 WK), PO. Patient recovered.

Methotrexate Side Effects Report #6128264-7
Methotrexate side effect was reported by a Health Professional from UNITED KINGDOM on Mar 04, 2009. Female patient, 63 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: chest discomfort, chest pain , cough, haemoglobin decreased, infection , oxygen saturation decreased, pneumonitis, respiratory failure, rib fracture. Methotrexate dosage: unknown. During the same period patient was treated with IBUPROFEN, PREDNISOLONE, TRAMADOL. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4884061-1
Methotrexate side effect was reported by a Health Professional from UNITED STATES on Jan 10, 2006. Female patient, 63 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: chronic obstructive pulmonary disease, condition aggravated, haemoglobin decreased. Methotrexate dosage: 15 MG 1XW ORAL. During the same period patient was treated with ABATACEPT, PREDNISONE, ISOSORBIDE, DILTIAZEM. Patient was hospitalized. Patient recovered.


Methotrexate Side Effects Report #5107002-0
Methotrexate side effect was reported by a Consumer or non-health professional from on Sept 01, 2006. Female patient, 61 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: b-cell lymphoma, blood alkaline phosphatase increased, blood lactate dehydrogenase increased, bone marrow disorder, haemoglobin decreased, lymphoproliferative disorder, mixed connective tissue disease, platelet count decreased, pulmonary hypertension . Methotrexate dosage: 5 TO 7.5 MGWEEK (NR, 1 IN 1 WK), NR. During the same period patient was treated with NSAIDS, STERIODS. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4955699-8
Methotrexate side effect was reported by a Consumer or non-health professional from FRANCE on Mar 17, 2006. Female patient, 55 years of age, was diagnosed with rheumatoid arthritis , anxiety  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: aplasia, autoimmune disorder, haemoglobin decreased, non-hodgkin's lymphoma, pancytopenia, platelet count decreased. Methotrexate dosage: unknown. During the same period patient was treated with VOLTARENE LP, DAFALGAN, STILNOX. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5055359-1
Methotrexate side effect was reported by a Consumer or non-health professional from KOREA, DEMOCRATIC PEOPLE'S REPUBLIC OF on July 07, 2006. Female patient, 46 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: anaplastic large cell lymphoma t- and null-cell types, ascites, costovertebral angle tenderness, dyspnoea, haemoglobin decreased, hepatosplenomegaly, lymphadenopathy, lymphadenopathy mediastinal, pleural effusion. Methotrexate dosage: unknown. During the same period patient was treated with FOLIC ACID, SULFASALAZINE, HYDROXYCHLOROQUINE SULPHATE. Patient recovered.

Methotrexate Side Effects Report #5108681-4
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Sept 06, 2006. Female patient, 46 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: ascites, costovertebral angle tenderness, dyspnoea, haemoglobin decreased, hepatosplenomegaly, lymphadenopathy, lymphoma , pleural effusion, red blood cell sedimentation rate increased. Methotrexate dosage: SEE TEXT (SEE TEXT, 7.5 TO 12.5 MG/WEEK), PO. During the same period patient was treated with SULFASALAZINE, HYDROXYCHLOROQUINE SULPHATE, SULINDAC, PREDNISOLONE, FOLIC ACID. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4939211-5
Methotrexate side effect was reported by a Consumer or non-health professional from TURKEY on Feb 21, 2006. Female patient, 46 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: blood glucose decreased, blood pressure increased, cardiac failure, cardiac tamponade, haemoglobin decreased, heart rate increased, hypotension, inflammation, palpitations. Methotrexate dosage: 15 MG WEEKLY IM. During the same period patient was treated with SULFASALAZINE, INDOMETHACIN, FOLIC ACID, PREDNISOLONE. Patient died.


Methotrexate Side Effects Report #4596573-9
Methotrexate side effect was reported by a Consumer or non-health professional from on July 19, 2004. Female patient, 34 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: haemoglobin decreased, uterine leiomyoma, vaginal haemorrhage. Methotrexate dosage: 20 MG WEEKLY, PO. During the same period patient was treated with ETANERCEPT, FOLIC ACID. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4643199-4
Methotrexate side effect was reported by a Consumer or non-health professional from on Apr 05, 2005. Male patient, 63 years of age, was diagnosed with pyoderma gangrenosum and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: cushingoid, diabetes mellitus, haemoglobin decreased, iatrogenic injury, peptic ulcer perforation, peritonitis, wound dehiscence. Methotrexate dosage: 7.5 MG WEEKLY PO. During the same period patient was treated with METHYLPREDNISOLONE, CLOBETASOL, CYCLOSPORINE, THALIDOMIDE, TRIAMCINOLONE, MYCOPHENOLATE MOFETIL, IMMUNOGLOBULIN. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4652179-4
Methotrexate side effect was reported by a Health Professional from on Apr 26, 2005. Male patient, 63 years of age, was diagnosed with pyoderma gangrenosum and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: diabetes mellitus, haemoglobin decreased, peptic ulcer perforation, wound dehiscence. Methotrexate dosage: unknown. During the same period patient was treated with KENALOG, METHYLPREDNISOLONE, CLOBETASOL, IMMUNOGLOBULIN, NEORAL, THALIDOMIDE, CELLCEPT. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4666688-5
Methotrexate side effect was reported by a Consumer or non-health professional from on Apr 05, 2005. Male patient, 63 years of age, was diagnosed with pyoderma gangrenosum and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: condition aggravated, cushingoid, diabetes mellitus, haemoglobin decreased, iatrogenic infection, peptic ulcer perforation, peritonitis, skin ulcer. Methotrexate dosage: 7.5 MG WEEKLY PO. During the same period patient was treated with METHYLPREDNISOLONE, CLOBETASOL, CYCLOSPORINE, THALIDOMIDE, TRIAMCINOLONE, MYCOPHENOLATE MOFETIL, IMMUNOGLOBULIN. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4928831-X
Methotrexate side effect was reported by a Health Professional from UNITED KINGDOM on Apr 26, 2005. Male patient, 63 years of age, was diagnosed with pyoderma gangrenosum and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: diabetes mellitus, haemoglobin decreased, peptic ulcer perforation, peritonitis, wound dehiscence. Methotrexate dosage: unknown. During the same period patient was treated with KENALOG, METHYLPREDNISOLONE, CLOBETASOL PROPIONATE, IMMUNE GLOBULIN INTRAVENOUS, NEORAL, THALIDOMIDE, CELLCEPT. Patient was hospitalized. Patient recovered.


Methotrexate Side Effects Report #4957848-4
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Feb 17, 2006. Male patient, 63 years of age, was diagnosed with pyoderma gangrenosum and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: diabetes mellitus, haemoglobin decreased, peptic ulcer perforation, peritonitis, postoperative wound complication, wound dehiscence. Methotrexate dosage: 7.5 MG WEEKLY PO. During the same period patient was treated with METHYLPREDNISOLONE, DERMOVATE, NEORAL, THALIDOMIDE, KENALOG, MYCOPHENOLATE MOFETIL. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4598717-1
Methotrexate side effect was reported by a Consumer or non-health professional from on May 13, 2004. Male patient, 58 years of age, was diagnosed with psoriatic arthropathy and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: blood fibrinogen decreased, bronchiectasis, diffuse alveolar damage, haemoglobin decreased, lung consolidation, lymphocyte percentage decreased, neutrophil percentage increased. Methotrexate dosage: 15 MG WEEKLY. During the same period patient was treated with METHYLPREDNISOLONE, FOLIC ACID. Patient died.

Methotrexate Side Effects Report #4987986-1
Methotrexate side effect was reported by a Consumer or non-health professional from on Apr 13, 2006. Male patient, 58 years of age, was diagnosed with psoriatic arthropathy and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alveolitis, bronchiectasis, candidiasis, diffuse alveolar damage, haemoglobin decreased, interstitial lung disease, lung consolidation, nodal arrhythmia, oral candidiasis. Methotrexate dosage: 15 MG/WEEK. During the same period patient was treated with METHYLPREDNISOLONE, FOLIC ACID. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #4672373-6
Methotrexate side effect was reported by a Consumer or non-health professional from on Sept 27, 2004. Male patient, 64 years of age, was diagnosed with psoriasis and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: bronchopulmonary aspergillosis, haemoglobin decreased, mouth ulceration, neutropenia, pharyngeal ulceration, white blood cell count decreased. Methotrexate dosage: 35 MG. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #5407914-4
Methotrexate side effect was reported by a Physician from UNITED STATES on July 20, 2007. Female patient, 36 years of age, was diagnosed with psoriasis and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal tenderness, aspartate aminotransferase abnormal, blood alkaline phosphatase increased, bone marrow granuloma, dizziness postural, haemoglobin decreased, histoplasmosis disseminated, infection in an immunocompromised host, lung infiltration. Methotrexate dosage: 7.5 MG, 2/WEEK. Patient was hospitalized. Patient recovered.


Methotrexate Side Effects Report #5657676-0
Methotrexate side effect was reported by a Consumer or non-health professional from on Mar 03, 2008. Male patient, child 6 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: cerebral haematoma, disease progression, haemoglobin decreased. Methotrexate dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, PREDNISONE, LEUCOVORIN CALCIUM, VINCRISTINE, IFOSFAMIDE, CYTARABINE, ETOPOSIDE, DOXORUBICIN. Patient died.

Methotrexate Side Effects Report #4557827-5
Methotrexate side effect was reported by a Consumer or non-health professional from on Dec 30, 2004. Female patient, 57 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: acute myeloid leukaemia, angina pectoris, b-cell lymphoma, haemoglobin decreased, infection , leukocytosis, platelet count decreased, pyrexia, tracheitis. Methotrexate dosage: 15 MILLIGRAM/3000MG/M2 INTRATHECAL/INTRAVENOUS (NOS). During the same period patient was treated with DOXORUBICIN, CYCLOPHOSPHAMIDE, VINDESINE, BLEOMYCIN, CYTARABINE, IFOSFAMIDE, ETOPOSIDE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4569638-5
Methotrexate side effect was reported by a Consumer or non-health professional from on Jan 18, 2005. Female patient, 57 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: acute leukaemia, angina pectoris, haemoglobin decreased, infection , platelet count decreased, pyrexia, tracheitis, white blood cell count decreased. Methotrexate dosage: 15 MILLIGRAM/3000 MG/M2, INTRATHECAL/INTRAVENOUS (NOS). During the same period patient was treated with DOXORUBICIN, CYCLOPHOSPHAMIDE, VINDESINE, BLEOMYCIN, CYTARABINE, IFOSFAMIDE, ETOPOSIDE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5648881-8
Methotrexate side effect was reported by a Health Professional from AUSTRALIA on Feb 25, 2008. Male patient, 75 years of age, was diagnosed with myasthenia gravis and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: haemoglobin decreased, lymphocyte count increased, mantle cell lymphoma, platelet count decreased, white blood cell count increased. Methotrexate dosage: 17.5 MG WEEKLY. During the same period patient was treated with IMMUNE GLOBULIN INTRAVENOUS, PREDNISOLONE, PYRIDOSTIGMINE BROMIDE. Patient recovered.

Methotrexate Side Effects Report #4975844-8
Methotrexate side effect was reported by a Physician from JAPAN on Mar 29, 2006. Male patient, 65 years of age, weighting 134.5 lb, was diagnosed with lymphoma  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: anaemia, blood alkaline phosphatase increased, blood potassium decreased, c-reactive protein increased, dialysis , haematocrit decreased, haemoglobin decreased, hepatic function abnormal. Methotrexate dosage: 3760 MG DAILY OTHER. During the same period patient was treated with DECADRON, ZOFRAN, LIPITOR, TAKEPRON, PURSENNID, MYSTAN, DIAMOX. Patient was hospitalized. Patient recovered.


Methotrexate Side Effects Report #5003547-2
Methotrexate side effect was reported by a Physician from SPAIN on Apr 28, 2006. Male patient, 16 years of age, was diagnosed with leukaemia, acute lymphocytic leukaemia, acute leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood lactate dehydrogenase increased, constipation , gamma-glutamyltransferase increased, haematocrit decreased, haemoglobin decreased, hemiparesis. Methotrexate dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, MERCAPTOPURINE, PREDNISONE, DEXAMETHASONE, DAUNORUBICIN, VINCRISTINE, CYTARABINE. Patient was hospitalized and became disabled. Patient died on 01/01/2000.

Methotrexate Side Effects Report #5404965-0
Methotrexate side effect was reported by a Health Professional from UNITED STATES on July 17, 2007. Female patient, child 7 years of age, was diagnosed with juvenile arthritis and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, cough, cryptococcosis, haemoglobin decreased, histoplasmosis disseminated, lymphadenopathy mediastinal, pharyngolaryngeal pain, splenomegaly, weight decreased. Methotrexate dosage: 12.5 MG, WEEKLY (11.5MG/M2/WEEK), ORAL, 15 MG WEEKLY, ORAL. During the same period patient was treated with NAPROXEN, PREDNISONE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4621832-0
Methotrexate side effect was reported by a Consumer or non-health professional from on Oct 30, 2003. Female patient, 29 years of age, was diagnosed with juvenile arthritis and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: blood magnesium decreased, culture urine positive, cystitis, dehydration, escherichia infection, haemoglobin decreased, pyelonephritis acute, vomiting. Methotrexate dosage: 17.5 MG WEEKLY SC. During the same period patient was treated with ENBREL, TIMOPTIC, ALPHAGAN, INFLAMASE MILD, PREDTE, FOLIC ACID. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5156656-1
Methotrexate side effect was reported by a Health Professional from UNITED STATES on Oct 31, 2006. Female patient, 15 years of age, was diagnosed with juvenile arthritis and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , alcohol use, dizziness , gastritis, haematocrit decreased, haemoglobin decreased, occult blood positive, tachycardia. Methotrexate dosage: 25 MG; QW; PO. During the same period patient was treated with PREDNISONE, NAPROSYN, FOLIC ACID, LANSOPRAZOLE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4928308-1
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Feb 15, 2006. Female patient was diagnosed with juvenile arthritis and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: haemoglobin decreased, lymphocyte count decreased, platelet count decreased, red blood cell count decreased. Methotrexate dosage: 5 MG WEEKLY ST. During the same period patient was treated with IBUPROFEN, PREDNISOLONE. Patient recovered.


Methotrexate Side Effects Report #4692322-4
Methotrexate side effect was reported by a Consumer or non-health professional from on Apr 28, 2005. Male patient, 65 years of age, was diagnosed with gastric cancer recurrent and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal discomfort, depressed level of consciousness, haemoglobin decreased, ileus, intestinal obstruction, intestinal perforation, neutrophil percentage decreased, oliguria, platelet count decreased. Methotrexate dosage: 140 MG PER_CYCLE IV. During the same period patient was treated with FLUOROURACIL, LEUCOVORIN. Patient died.

Methotrexate Side Effects Report #4698003-5
Methotrexate side effect was reported by a Consumer or non-health professional from on Apr 28, 2005. Male patient, 65 years of age, was diagnosed with gastric cancer recurrent and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: ascites, depressed level of consciousness, gastric cancer recurrent, granulocyte count decreased, haemoglobin decreased, ileus, intestinal obstruction, intestinal perforation, neutrophil percentage decreased. Methotrexate dosage: 140 MG PER_CYCLE IV. During the same period patient was treated with FLUOROURACIL, LEUCOVORIN. Patient died.

Methotrexate Side Effects Report #4811308-X
Methotrexate side effect was reported by a Health Professional from UNITED STATES on Oct 26, 2005. Male patient, weighting 182.3 lb, was diagnosed with central nervous system lymphoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: chills, dyspnoea exertional, ear pain, haemoglobin decreased, nasal disorder, neutrophil count decreased, pharyngolaryngeal pain, platelet count decreased, pyrexia. Methotrexate dosage: 8MG/M2 DAY 1 + 15 Q CYCLE IV DRIP. During the same period patient was treated with THIOTEPA. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5730267-9
Methotrexate side effect was reported by a Consumer or non-health professional from ITALY on Apr 24, 2008. Female patient, 84 years of age, was diagnosed with breast cancer  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: anaemia, asthenia, blood bilirubin increased, bone marrow toxicity, diarrhoea, haemoglobin decreased, hyperkalaemia, intestinal obstruction, leukopenia. Methotrexate dosage: 2.5 MG TWICE A DAY, 2 DAYS WEEKLY ORAL. During the same period patient was treated with CYCLOPHOSPHAMIDE. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #4559391-3
Methotrexate side effect was reported by a Health Professional from on Jan 04, 2005. Female patient, 58 years of age, was diagnosed with breast cancer  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: epistaxis, haemoglobin decreased, mouth ulceration, neutrophil count decreased, white blood cell count decreased. Methotrexate dosage: 75 MG FREQ UNK; IV. During the same period patient was treated with FLUOROURACIL, CYCLOPHOSPHAMIDE, LANSOPRAZOLE, SENNA, MORPHINE SULPHATE, LACTULOSE, FRUSEMIDE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5363026-X
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on June 07, 2007. Male patient, 17 years of age, was diagnosed with bone sarcoma, metastases to lung, metastasis and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: haemoglobin decreased, melaena, metastases to bone, metastases to lung, metastases to stomach, obliterative bronchiolitis, osteosarcoma metastatic, syncope, tumour necrosis. Methotrexate dosage: unknown. During the same period patient was treated with DOXORUBICIN, IFOSFAMIDE, CISPLATIN. Patient recovered.

Methotrexate Side Effects Report #4699651-9
Methotrexate side effect was reported by a Consumer or non-health professional from on Jan 27, 2005. Female patient, 17 years of age, was diagnosed with bone sarcoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood bilirubin increased, bulbar palsy, depressed level of consciousness, gamma-glutamyltransferase increased, haematocrit decreased, haemoglobin decreased, leukoencephalopathy. Methotrexate dosage: unknown. During the same period patient was treated with DOXORUBICIN HYDROCHLORIDE, CISPLATIN, CALCIUM FOLINATE. Patient recovered.

Methotrexate Side Effects Report #4902410-2
Methotrexate side effect was reported by a Consumer or non-health professional from JAPAN on Jan 23, 2006. Female patient, 69 years of age, was diagnosed with arthralgia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: antinuclear antibody positive, arthralgia, blood lactate dehydrogenase increased, cough, dyspnoea, haematocrit decreased, haematuria, haemoglobin decreased, hypoxia. Methotrexate dosage: unknown. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5765154-3
Methotrexate side effect was reported by a Consumer or non-health professional from TURKEY on June 02, 2008. Male patient, 13 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: anal ulcer, chest pain , dysphagia, erythema, febrile neutropenia, gastroenteritis , haemoglobin decreased, heart rate increased, lip ulceration. Methotrexate dosage: unknown. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5909494-3
Methotrexate side effect was reported by a Consumer or non-health professional from TURKEY on Sept 24, 2008. Male patient, 13 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: anal ulcer, asthenia, diarrhoea haemorrhagic, erythema, gastroenteritis , haemoglobin decreased, lip ulceration, mouth ulceration, platelet count decreased. Methotrexate dosage: unknown. Patient was hospitalized. Patient recovered.


Methotrexate Side Effects Report #4868607-5
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Dec 14, 2005. Female patient, 60 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: blood glucose increased, cardiac arrest , coronary artery occlusion, electrocardiogram st segment elevation, haemoglobin decreased, mean arterial pressure increased, myocardial infarction, post procedural complication, ventricular tachycardia. Methotrexate dosage: unknown. During the same period patient was treated with ENBREL, PARACETAMOL, DICLOFENAC, CODEINE, FOLIC ACID. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4553315-0
Methotrexate side effect was reported by a Consumer or non-health professional from on Nov 11, 2004. Female patient, 53 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, atelectasis, bacterial infection , haemoglobin decreased, hypotension, lymphopenia, pharyngolaryngeal pain, pneumonia , pulmonary oedema. Methotrexate dosage: 15 MG WEEKLY SC. During the same period patient was treated with PREDNISONE, ENBREL, LOPID, LEVOTHYROXINE, PROCARDIA, DYAZIDE, FOLIC ACID, PEPCID. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5376394-X
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on June 27, 2007. Male patient, weighting 31.75 lb, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, blood glucose decreased, blood pressure diastolic decreased, haemoglobin decreased, heart rate increased, hypothermia , peripheral coldness, prothrombin time prolonged, somnolence. Methotrexate dosage: 100 MG. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5951247-4
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Nov 12, 2008. Male patient, weighting 167.8 lb, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , colitis, dehydration, febrile neutropenia, haemoglobin decreased, headache , hydrocephalus , hypertension, meningitis staphylococcal. Methotrexate dosage: unknown. During the same period patient was treated with RITUXIMAB, TEMOZOLOMIDE, DILAUDID. Patient was hospitalized. Patient recovered.