Methotrexate and fatigue Patient Reports February 11, 2012

Methotrexate Side Effects Report #5832527-X
Methotrexate side effect was reported by a Physician from JAPAN on July 23, 2008. Female patient, 51 years of age, was diagnosed with still's disease adult onset and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: coagulopathy, disease recurrence, fatigue, hepatic failure, histiocytosis haematophagic, still's disease adult onset. Methotrexate dosage: 6 MG/WEEK,; 15 MG/WEEK. During the same period patient was treated with INDOMETHACIN, DEXAMETHASONE, PREDNISOLONE, BETAMETHASONE, METHYLPREDNISOLONE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4790446-4
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Sept 19, 2005. Female patient, 46 years of age, weighting 164.0 lb, was diagnosed with sarcoidosis and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: fatigue, haemoptysis. Methotrexate dosage: 7.5 MG, 1/WEEK, ORAL. During the same period patient was treated with COUMADIN, VERAPAMIL, DYAZIDE, SINGULAIR, PREDNISONE, OXYGEN. Patient recovered.

Methotrexate Side Effects Report #5813467-9
Methotrexate side effect was reported by a Health Professional from UNITED STATES on July 16, 2008. Male patient, 81 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: fatigue, increased tendency to bruise, pancytopenia. Methotrexate dosage: 15 MG QWEEK PO. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4923829-X
Methotrexate side effect was reported by a Pharmacist from UNITED STATES on Feb 24, 2006. Female patient, 79 years of age, weighting 156.5 lb, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: anuria, asthenia, brain natriuretic peptide increased, chills, dyspnoea, fatigue, immunosuppression, lung infiltration, lung injury. Methotrexate dosage: 10 MG WEEKLY IM. Patient was hospitalized. Patient recovered.


Methotrexate Side Effects Report #4557324-7
Methotrexate side effect was reported by a Health Professional from on Jan 19, 2005. Male patient, 78 years of age, weighting 176.0 lb, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: anaemia, chills, dyspnoea, fatigue, hyperhidrosis, immunosuppression, lung infiltration, myocardial infarction, oxygen saturation decreased. Methotrexate dosage: 15MG WEEK ORAL. During the same period patient was treated with ENBREL, GLUCOPHAGE, GLYBURIDE, ENALAPRIL, ZOCOR, GEMFIBROZIL, ACTONEL, ASPIRIN. Patient died on 11/03/2004.

Methotrexate Side Effects Report #5066845-2
Methotrexate side effect was reported by a Consumer or non-health professional from on July 05, 2006. Female patient, 77 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal mass, blood lactate dehydrogenase increased, diffuse large b-cell lymphoma, fatigue, hepatomegaly, hyperhidrosis, lymphadenopathy, lymphoproliferative disorder, non-hodgkin's lymphoma. Methotrexate dosage: 15 MG PER WEEK (1 IN 1 WK),. During the same period patient was treated with CYCLOSPORINE, CHLOROQUINE, SULFASALAZINE, RITUXIMAB, LEFLUNOMIDE, ENBREL. Patient recovered.

Methotrexate Side Effects Report #4886097-3
Methotrexate side effect was reported by a Pharmacist from UNITED STATES on Jan 18, 2006. Female patient, 75 years of age, weighting 114.6 lb, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: aphthous stomatitis, dehydration, fatigue, mucosal erosion, oral intake reduced, oral pain, palatal disorder, tongue disorder. Methotrexate dosage: 2.5 MG 5X/WK. During the same period patient was treated with ATIVAN, ALBUTEROL SULPHATE, VICODIN, FLEXERIL, VIT B, REMICADE, IMODIUM, FOLIC ACID. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5704282-5
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Mar 31, 2008. Female patient, 73 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: anaemia, bronchopneumonia, cardiac failure, chronic obstructive pulmonary disease, cytomegalovirus infection , electrocardiogram p pulmonale, fatigue, leukopenia, liver function test abnormal. Methotrexate dosage: unknown. During the same period patient was treated with CYCLOSPORINE. Patient died.

Methotrexate Side Effects Report #5405005-X
Methotrexate side effect was reported by a Physician from UNITED STATES on July 20, 2007. Male patient, 72 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: anorexia, asthenia, atelectasis, ecchymosis, fatigue, histoplasmosis disseminated, pancytopenia, pyrexia, speech disorder. Methotrexate dosage: 15 MG, WEEKLY, ORAL. During the same period patient was treated with PREDNISONE. Patient recovered.


Methotrexate Side Effects Report #4616631-X
Methotrexate side effect was reported by a Consumer or non-health professional from on Mar 02, 2005. Male patient, 72 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: anorexia, asthenia, biopsy bone marrow abnormal, ecchymosis, fatigue, histoplasmosis disseminated, opportunistic infection, pancytopenia, speech disorder. Methotrexate dosage: 15 MG WEEKLY PO. During the same period patient was treated with PREDNISOLONE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5825778-1
Methotrexate side effect was reported by a Pharmacist from UNITED STATES on July 28, 2008. Male patient, 68 years of age, weighting 203.0 lb, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: cough, fatigue, influenza, oxygen saturation decreased, pain , pyrexia. Methotrexate dosage: 17.5MG WEEKLY IM. During the same period patient was treated with FELDENE, MOMETASONE CREAM, LASIX, HUMIRA, NORVASC, DIOVAN, VALIUM, RANITIDINE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5631719-2
Methotrexate side effect was reported by a Health Professional from KOREA, DEMOCRATIC PEOPLE'S REPUBLIC OF on Jan 30, 2008. Female patient, 66 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: anorexia, encephalopathy, fatigue, hepatic failure, hepatitis b , malaise. Methotrexate dosage: 10 MG, QW, ORAL. During the same period patient was treated with PREDNISOLONE. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #4579117-7
Methotrexate side effect was reported by a Consumer or non-health professional from on Dec 16, 2003. Male patient, 60 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: asthenia, chest pain , chills, cough, dyspnoea, fatigue, leukocytosis, pneumonia , pneumonitis. Methotrexate dosage: 12.5 MG 1X PER 1 WK, ORAL. During the same period patient was treated with ENBREL, PREDNISONE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4986972-5
Methotrexate side effect was reported by a Pharmacist from UNITED STATES on Apr 28, 2006. Male patient, 60 years of age, weighting 169.0 lb, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: anaemia of chronic disease, blood amylase increased, dizziness , fatigue, inflammation, iron deficiency, lipase increased, platelet production decreased. Methotrexate dosage: 25 MG ONCE A WEEK SQ. During the same period patient was treated with PREDNISONE, HYDROCHLOROTHIAZIDE, CITALOPRAM HYDROBROMIDE, CYCLOBENZAPRINE, HYDROXYCHLOROQUINE SULPHATE, IBUPROFEN, LISINOPRIL. Patient was hospitalized. Patient recovered.


Methotrexate Side Effects Report #4983210-4
Methotrexate side effect was reported by a Physician from TAIWAN, PROVINCE OF CHINA on Apr 06, 2006. Female patient, 55 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood pressure systolic increased, carbuncle, dermatitis exfoliative, fatigue, febrile neutropenia. Methotrexate dosage: 7.5 MG PER WEEK. During the same period patient was treated with CELECOXIB, PREDNISOLONE, SULFASALAZINE, FOLIC ACID. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5810827-7
Methotrexate side effect was reported by a Health Professional from UNITED STATES on June 30, 2008. Female patient, 44 years of age, weighting 169.0 lb, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, anaemia, catheter related complication, condition aggravated, encephalopathy, fatigue, gastrointestinal haemorrhage, hypercapnia, hypoxia. Methotrexate dosage: unknown. During the same period patient was treated with ADALIMUMAB, AMLODIPINE BESYLATE, IBUPROFEN, ACETAMINOPHEN, ACETAMINOPHEN W. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5952583-8
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Oct 10, 2007. Female patient was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: fatigue, headache , nausea . Methotrexate dosage: 0.06 ML X 1X PER WEEK. During the same period patient was treated with HUMIRA, LEVOXYL, HYDROCHLOROTHIAZIDE. Patient recovered.

Methotrexate Side Effects Report #6063501-9
Methotrexate side effect was reported by a Consumer or non-health professional from on Feb 02, 2009. Female patient, 48 years of age, was diagnosed with psoriatic arthropathy, lung infiltration and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: cough, disease progression, dyspnoea, dyspnoea exertional, fatigue, pleural effusion, pulmonary function test decreased, rheumatoid nodule, serology abnormal. Methotrexate dosage: unknown. During the same period patient was treated with BROAD SPECTRUM ANTIBIOTICS, PREDNISONE, AZATHIOPRINE, ASPIRIN. Patient recovered.

Methotrexate Side Effects Report #5127239-4
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Sept 28, 2006. Male patient, 37 years of age, was diagnosed with psoriasis and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: cutaneous leishmaniasis, fatigue, nausea , transaminases increased. Methotrexate dosage: 12.5 MG WEEKLY. Patient recovered.


Methotrexate Side Effects Report #5853429-9
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Dec 28, 2007. Male patient, weighting 142.2 lb, was diagnosed with juvenile arthritis and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , anorexia, fatigue, malaise, weight decreased. Methotrexate dosage: 15 MG WEEKLY SC. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5754806-7
Methotrexate side effect was reported by a Pharmacist from UNITED STATES on May 19, 2008. Female patient, 35 years of age, was diagnosed with glioblastoma multiforme and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: areflexia, brain compression, brain herniation, brain oedema, depressed level of consciousness, fatigue, loss of consciousness, nausea . Methotrexate dosage: unknown. During the same period patient was treated with DEXTROSE, BICARBONATE, PHENOBARBITAL, DEXAMETHASONE, LEUCOVORIN CALCIUM. Patient died.

Methotrexate Side Effects Report #4670591-4
Methotrexate side effect was reported by a Physician from on Dec 08, 2004. Male patient, 75 years of age, was diagnosed with desmoid tumour and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: fatigue, leukopenia, nausea . Methotrexate dosage: 50 MG WEEKLY. During the same period patient was treated with VINBLASTINE. Patient recovered.

Methotrexate Side Effects Report #4670620-8
Methotrexate side effect was reported by a Pharmacist from on Dec 08, 2004. Male patient, 58 years of age, was diagnosed with desmoid tumour and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alopecia, fatigue, nausea , polyneuropathy. Methotrexate dosage: 50 MG WEEKLY. During the same period patient was treated with VINBLASTINE SULPHATE. Patient recovered.

Methotrexate Side Effects Report #4670644-0
Methotrexate side effect was reported by a Physician from on Dec 08, 2004. Female patient, 40 years of age, was diagnosed with desmoid tumour and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: diarrhoea, fatigue, nausea , polyneuropathy. Methotrexate dosage: 50 MG WEEKLY. During the same period patient was treated with VINBLASTINE SULPHATE. Patient recovered.


Methotrexate Side Effects Report #6110705-2
Methotrexate side effect was reported by a Physician from UNITED STATES on Feb 25, 2009. Female patient, 74 years of age, was diagnosed with dermatomyositis and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: breast cancer , breast mass, calcinosis, fatigue, soft tissue disorder. Methotrexate dosage: unknown. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5526161-9
Methotrexate side effect was reported by a Health Professional from UNITED KINGDOM on Nov 08, 2007. Female patient, 48 years of age, was diagnosed with connective tissue disorder  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: condition aggravated, diffuse large b-cell lymphoma, epstein-barr virus infection, fatigue, lymphoproliferative disorder, night sweats, polyarthritis, raynaud's phenomenon, weight decreased. Methotrexate dosage: 10 MG WEEKLY. During the same period patient was treated with HYDROXYCHLOROQUINE SULPHATE, PREDNISOLONE. Patient recovered.

Methotrexate Side Effects Report #5537917-0
Methotrexate side effect was reported by a Consumer or non-health professional from on Dec 04, 2007. Female patient, 48 years of age, was diagnosed with connective tissue disorder  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: cough, epstein-barr virus test positive, fatigue, lymphoproliferative disorder, night sweats, pyrexia, raynaud's phenomenon, sclerodactylia. Methotrexate dosage: unknown. During the same period patient was treated with HYDROXYCHLOROQUINE SULPHATE, PREDNISOLONE. Patient recovered.

Methotrexate Side Effects Report #4718732-4
Methotrexate side effect was reported by a Health Professional from UNITED STATES on July 07, 2005. Male patient, 70 years of age, weighting 224.9 lb, was diagnosed with central nervous system lymphoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: fatigue, febrile neutropenia, lethargy, pancytopenia, renal failure acute. Methotrexate dosage: unknown. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4831434-9
Methotrexate side effect was reported by a Health Professional from UNITED STATES on Nov 16, 2005. Male patient, weighting 182.3 lb, was diagnosed with central nervous system lymphoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: chills, confusional state, dyspnoea, fatigue, hypoxia, irritability, pancytopenia, pharyngolaryngeal pain, pneumonia . Methotrexate dosage: 8 MG/M2 DAY 1 AND 15 Q CYCLE IV DRIP. During the same period patient was treated with THIOTEPA. Patient was hospitalized. Patient recovered.


Methotrexate Side Effects Report #4662632-5
Methotrexate side effect was reported by a Pharmacist from on May 13, 2005. Female patient, child 11 years of age, weighting 132.5 lb, was diagnosed with bone sarcoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: coagulopathy, fatigue, hepatic failure, hepatitis , hypertension, nausea , prothrombin time prolonged, renal failure acute. Methotrexate dosage: unknown. Patient recovered.

Methotrexate Side Effects Report #5285309-4
Methotrexate side effect was reported by a Consumer or non-health professional from on Mar 26, 2007. Female patient, 66 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: blood osmolarity abnormal, depressed level of consciousness, fatigue, hyponatraemia, hypothalamo-pituitary disorder, inappropriate antidiuretic hormone secretion. Methotrexate dosage: 15 MG X 1 DOSE. During the same period patient was treated with PREDNISOLONE, CYTARABINE, IDARUBICIN, MITOXANTRONE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5598051-7
Methotrexate side effect was reported by a Physician from JAPAN on Jan 02, 2008. Female patient, 66 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: altered state of consciousness, fatigue, inappropriate antidiuretic hormone secretion. Methotrexate dosage: 15 MG INTRATHECAL. During the same period patient was treated with CYTARABINE, PREDNISONE. Patient recovered.

Methotrexate Side Effects Report #5107698-3
Methotrexate side effect was reported by a Consumer or non-health professional from on Sept 01, 2006. Female patient, 51 years of age, was diagnosed with acute promyelocytic leukaemia, nervous system disorder and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: c-reactive protein increased, extrasystoles, fatigue, hypokalaemia, hypomagnesaemia, pathogen resistance, pharyngitis, pyrexia, speech disorder. Methotrexate dosage: (15 MG), IT. During the same period patient was treated with ARSENIC TRIOXIDE, ARSENIC TRIOXIDE, CYTARABINE, PREDNISOLONE. Patient recovered.

Methotrexate Side Effects Report #5924682-8
Methotrexate side effect was reported by a Physician from JAPAN on Oct 01, 2008. Female patient, child 5 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal distension, abdominal pain upper, ascites, depressed level of consciousness, disease recurrence, disseminated intravascular coagulation, fatigue, hepatic necrosis, hepatomegaly. Methotrexate dosage: 9MG INTRATHECAL; DAYS 1 AND 15. Patient was hospitalized. Patient died.


Methotrexate Side Effects Report #4771002-0
Methotrexate side effect was reported by a Health Professional from FRANCE on Sept 07, 2005. Male patient, 61 years of age, was diagnosed with acute leukaemia, acute lymphocytic leukaemia, fungal infection  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: anaemia, cough, disease progression, dysphonia, fatigue, hypotension, leukopenia, pseudomonal sepsis, thrombocytopenia. Methotrexate dosage: unknown. During the same period patient was treated with PURINETHOL, SCH, HEPARIN, THIAMINE, ALDACTONE, CELECTOL, INSULIN, OMEPRAZOLE. Patient was hospitalized. Patient died on 08/13/2005.

Methotrexate Side Effects Report #4771002-0
Methotrexate side effect was reported by a Health Professional from FRANCE on Sept 07, 2005. Male patient, 61 years of age, was diagnosed with acute leukaemia, acute lymphocytic leukaemia, fungal infection  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: anaemia, cough, disease progression, dysphonia, fatigue, hypotension, leukopenia, pseudomonal sepsis, thrombocytopenia. Methotrexate dosage: unknown. During the same period patient was treated with PURINETHOL, POSACONAZOLE, HEPARIN, THIAMINE, ALDACTONE, CELECTOL, INSULIN, OMEPRAZOLE. Patient was hospitalized. Patient died on 08/13/2005.

Methotrexate Side Effects Report #5027795-0
Methotrexate side effect was reported by a Physician from UNITED STATES on June 14, 2006. Female patient, 82 years of age, weighting 186.0 lb, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: dyspnoea, fatigue, lung infiltration, pneumonitis, pyrexia. Methotrexate dosage: 25 MG SC WEEKLY. During the same period patient was treated with REMICADE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4961626-X
Methotrexate side effect was reported by a Pharmacist from CANADA on Mar 14, 2006. Male patient, 54 years of age, weighting 175.0 lb, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: arthralgia, fatigue, feeling cold, groin pain, tremor, vomiting. Methotrexate dosage: 1 ML WEEKLY SC. During the same period patient was treated with LEFLUNOMIDE, NAPROSYN, OMEPRAZOLE, NASONEX. Patient recovered.

Methotrexate Side Effects Report #4596598-3
Methotrexate side effect was reported by a Consumer or non-health professional from on June 25, 2004. Female patient, 53 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: c-reactive protein increased, fatigue, pyrexia. Methotrexate dosage: unknown. During the same period patient was treated with INFLIXIMAB, SULFASALAZINE. Patient recovered.


Methotrexate Side Effects Report #5087573-3
Methotrexate side effect was reported by a Health Professional from JAPAN on June 23, 2006. Female patient, 35 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: c-reactive protein increased, disorientation, fatigue, hyperaesthesia, hyperkalaemia, neuralgia, paraesthesia, pneumonia bacterial, pruritus. Methotrexate dosage: 10 MG/M2/D. During the same period patient was treated with ACYCLOVIR, MICAFUNGIN, MEROPENEM, VANCOMYCIN, NEUPOGEN, MYCOPHENOLATE MOFETIL, SANDIMMUNE. Patient was hospitalized. Patient died on 01/02/2004.

Methotrexate Side Effects Report #5345557-1
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on June 01, 2007. Male patient, weighting 191.8 lb, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: anaemia, aplasia pure red cell, blood immunoglobulin g decreased, cardiac failure congestive, dyspnoea at rest, fatigue, fluid retention, oedema peripheral, oxygen saturation decreased. Methotrexate dosage: 40 MG. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4667365-7
Methotrexate side effect was reported by a Consumer or non-health professional from on May 19, 2005. Female patient, weighting 183.2 lb, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: fatigue, malaise, supraventricular tachycardia. Methotrexate dosage: 15 MG. During the same period patient was treated with HYDROCORTISONE, VINCRISTINE, LEUCOVORIN, BACTRIM DS, LISINOPRIL, DIAZIDE, HUMALOG. Patient was hospitalized. Patient recovered.