Methotrexate and dyspnoea Patient Reports February 11, 2012

Methotrexate Side Effects Report #5128378-4
Methotrexate side effect was reported by a Consumer or non-health professional from JAPAN on Sept 27, 2006. Female patient, 64 years of age, was diagnosed with stem cell transplant, abscess  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: blister, dyspnoea, eyelid oedema, face oedema, graft versus host disease, herpes zoster, intubation, life support, local swelling. Methotrexate dosage: unknown. During the same period patient was treated with PREDNISOLONE, CYCLOSPORINE, FLUDARABINE, BUSULFAN, MELPHALAN. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5142157-3
Methotrexate side effect was reported by a Consumer or non-health professional from JAPAN on Sept 27, 2006. Female patient, 64 years of age, was diagnosed with stem cell transplant, abscess  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: blister, dyspnoea, eyelid oedema, face oedema, graft versus host disease, herpes zoster, intubation, laryngeal oedema, life support. Methotrexate dosage: unknown. During the same period patient was treated with PREDNISOLONE, NEORAL, FLUDARABINE, BUSULFAN, MELPHALAN. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5224683-1
Methotrexate side effect was reported by a Pharmacist from UNITED STATES on Jan 29, 2007. Male patient, 65 years of age, weighting 235.4 lb, was diagnosed with scleritis and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: back pain , bacteria urine, bronchopneumonia, chills, diarrhoea, dyspnoea, hypotension, lung infiltration. Methotrexate dosage: 25MG EVERY WEEK SQ. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5409487-9
Methotrexate side effect was reported by a Pharmacist from UNITED STATES on Aug 07, 2007. Female patient, 84 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: diarrhoea, dyspnoea, electrocardiogram abnormal, hyperkalaemia, hyponatraemia, multi-organ disorder, renal failure acute, septic shock. Methotrexate dosage: 10 MG DAILY PO. During the same period patient was treated with LASIX, PREVACID, PREDNISONE, LOTREL, ATENOLOL, FOLIC ACID, VITAMIN CAP. Patient was hospitalized. Patient recovered.


Methotrexate Side Effects Report #4923829-X
Methotrexate side effect was reported by a Pharmacist from UNITED STATES on Feb 24, 2006. Female patient, 79 years of age, weighting 156.5 lb, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: anuria, asthenia, brain natriuretic peptide increased, chills, dyspnoea, fatigue, immunosuppression, lung infiltration, lung injury. Methotrexate dosage: 10 MG WEEKLY IM. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5473637-9
Methotrexate side effect was reported by a Consumer or non-health professional from on Sept 24, 2007. Male patient, 78 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: coccidioidomycosis, dyspnoea, night sweats, normochromic normocytic anaemia, productive cough, pyrexia, respiratory failure, skin lesion, weight decreased. Methotrexate dosage: unknown. During the same period patient was treated with INFLIXIMAB. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #4557324-7
Methotrexate side effect was reported by a Health Professional from on Jan 19, 2005. Male patient, 78 years of age, weighting 176.0 lb, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: anaemia, chills, dyspnoea, fatigue, hyperhidrosis, immunosuppression, lung infiltration, myocardial infarction, oxygen saturation decreased. Methotrexate dosage: 15MG WEEK ORAL. During the same period patient was treated with ENBREL, GLUCOPHAGE, GLYBURIDE, ENALAPRIL, ZOCOR, GEMFIBROZIL, ACTONEL, ASPIRIN. Patient died on 11/03/2004.

Methotrexate Side Effects Report #6027447-4
Methotrexate side effect was reported by a Health Professional from LITHUANIA on Dec 23, 2008. Female patient, 76 years of age, was diagnosed with rheumatoid arthritis , connective tissue disorder  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: asthenia, depressed level of consciousness, dyspnoea, haemangioma, hypotension, keratitis, pulmonary fibrosis , pyrexia, septic shock. Methotrexate dosage: unknown. During the same period patient was treated with AZATHIOPRINE, PREDNISOLONE, PLAQUENIL. Patient was hospitalized. Patient died on 08/20/2008.

Methotrexate Side Effects Report #6056304-2
Methotrexate side effect was reported by a Health Professional from LITHUANIA on Jan 16, 2009. Female patient, 76 years of age, was diagnosed with rheumatoid arthritis , connective tissue disorder  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, asthenia, depressed level of consciousness, diffuse large b-cell lymphoma, dyspnoea, haemangioma of liver, keratitis, leukocytoclastic vasculitis, localised infection. Methotrexate dosage: unknown. During the same period patient was treated with AZATHIOPRINE, PREDNISOLONE, PLAQUENIL. Patient was hospitalized. Patient died on 08/20/2008.


Methotrexate Side Effects Report #6022374-0
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Dec 21, 2008. Male patient, 75 years of age, weighting 150.0 lb, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: blood count abnormal, chest pain , cough, dyspnoea. Methotrexate dosage: unknown. Patient died on 10/23/2008.

Methotrexate Side Effects Report #5120436-3
Methotrexate side effect was reported by a Consumer or non-health professional from SWITZERLAND on Sept 22, 2006. Female patient, 74 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: aspergillosis, asthenia, candidiasis, cardiovascular insufficiency, dyspnoea, enterococcal infection, hepatic enzyme increased, pneumocystis jiroveci pneumonia. Methotrexate dosage: unknown. During the same period patient was treated with PREDNISONE, NSAID, IMUREK. Patient died.

Methotrexate Side Effects Report #5150266-8
Methotrexate side effect was reported by a Pharmacist from UNITED STATES on Nov 09, 2006. Male patient, 74 years of age, weighting 176.8 lb, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: dyspnoea, respiratory distress. Methotrexate dosage: 15 MG PO WEEKLY. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4579125-6
Methotrexate side effect was reported by a Consumer or non-health professional from on Apr 20, 2004. Female patient, 73 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: dyspnoea, interstitial lung disease. Methotrexate dosage: 15 MG 1X PER 1 WK, ORAL. During the same period patient was treated with PREDNISONE, DIOVAN, IBUPROFEN, TYLENOL. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4616649-7
Methotrexate side effect was reported by a Consumer or non-health professional from on Aug 27, 2004. Female patient, 73 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: dyspnoea, hyperhidrosis, myalgia, pneumonitis. Methotrexate dosage: 20 MG WEEKLY PO. During the same period patient was treated with ROFECOXIB, FOLIC ACID, OMEPRAZOLE, ATORVASTATIN, IRON SULPHATE, ASPIRIN. Patient was hospitalized. Patient recovered.


Methotrexate Side Effects Report #4764682-7
Methotrexate side effect was reported by a Health Professional from UNITED KINGDOM on Aug 26, 2004. Female patient, 73 years of age, was diagnosed with rheumatoid arthritis , cardiovascular disorder, anaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: dyspnoea, hyperhidrosis, myalgia, pneumonitis. Methotrexate dosage: unknown. During the same period patient was treated with FOLIC ACID, ACETAMINOPHEN AND PROPOXYPHENE HYDROCHLORIDE, OMEPRAZOLE, ATORVASTATIN CALCIUM, AMILORIDE HYDROCHLORIDE AND FUROSEMIDE, FERROUS SULPHATE, ASPIRIN, VIOXX. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5613410-1
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Jan 16, 2008. Male patient, 71 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: angiocentric lymphoma, blood lactate dehydrogenase increased, c-reactive protein increased, diffuse alveolar damage, dyspnoea, epstein-barr virus antibody positive, haemoglobin decreased, hypoxia, interstitial lung disease. Methotrexate dosage: 8MG/WK. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #5509439-4
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Oct 30, 2007. Male patient, 69 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: condition aggravated, dyspnoea, immunodeficiency, interstitial lung disease, nasopharyngitis, oxygen saturation decreased, viral infection . Methotrexate dosage: unknown. During the same period patient was treated with HUMIRA, SULFA. Patient died on 09/06/2007.

Methotrexate Side Effects Report #5364302-7
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on June 05, 2007. Male patient, 67 years of age, weighting 198.0 lb, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: cardiac failure congestive, dyspnoea. Methotrexate dosage: 20 MG SC. During the same period patient was treated with RITUXIMAB, FOLIC ACID. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #4579119-0
Methotrexate side effect was reported by a Physician from on Mar 29, 2004. Female patient, 66 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: condition aggravated, cough, dyspnoea, hypoxia, lung disorder. Methotrexate dosage: unknown. During the same period patient was treated with ENBREL, NEORAL, PLAQUENIL, SYNTHROID, FLOVENT, ALBUTEROL, SEREVENT, PREMARIN. Patient recovered.


Methotrexate Side Effects Report #4616059-2
Methotrexate side effect was reported by a Consumer or non-health professional from on Mar 11, 2005. Female patient, 66 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: anorexia, cardiac failure, dyspnoea, lymphoma , malaise, multi-organ failure, pancytopenia, pericardial effusion, pseudo lymphoma. Methotrexate dosage: 4 MG 1XW ORAL. During the same period patient was treated with INFLIXIMAB, PREDNISOLONE, SULINDAC, TEPRENONE, DOXAZOSINE MESILATE. Patient was hospitalized. Patient died on 06/03/2004.

Methotrexate Side Effects Report #4596775-1
Methotrexate side effect was reported by a Consumer or non-health professional from on June 23, 2004. Female patient, 63 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: dyspnoea, productive cough, respiratory failure, respiratory tract infection. Methotrexate dosage: unknown. During the same period patient was treated with ETANERCEPT, PREDNISOLONE, ALENDRONATE, CELECOXIB, RAMIPRIL. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #4652861-9
Methotrexate side effect was reported by a Consumer or non-health professional from on Apr 15, 2005. Female patient, 63 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: computerised tomogram abnormal, condition aggravated, dyspnoea, rheumatoid lung. Methotrexate dosage: 15 MG WEEKLY PO. During the same period patient was treated with INFLIXIMAB, PREDNISOLONE, ALENDRONATE, CALCIUM LACTATE, VITAMIN D. Patient recovered.

Methotrexate Side Effects Report #4579117-7
Methotrexate side effect was reported by a Consumer or non-health professional from on Dec 16, 2003. Male patient, 60 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: asthenia, chest pain , chills, cough, dyspnoea, fatigue, leukocytosis, pneumonia , pneumonitis. Methotrexate dosage: 12.5 MG 1X PER 1 WK, ORAL. During the same period patient was treated with ENBREL, PREDNISONE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4544884-5
Methotrexate side effect was reported by a Health Professional from on Dec 20, 2004. Female patient, 59 years of age, was diagnosed with rheumatoid arthritis , depression  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: cough, dyspnoea, hypoxia, pneumonitis. Methotrexate dosage: 15 MG WEEKLY PO. During the same period patient was treated with NAPROXEN, PARACETAMOL, IMIPRAM. Patient recovered.


Methotrexate Side Effects Report #4958365-8
Methotrexate side effect was reported by a Pharmacist from UNITED STATES on Mar 29, 2006. Male patient, 59 years of age, weighting 156.3 lb, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: dyspnoea. Methotrexate dosage: 20 MG SUBQ ONCE /WK. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5097380-3
Methotrexate side effect was reported by a Physician from UNITED STATES on Aug 18, 2006. Female patient, 58 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: chest pain , dyspnoea, hepatic enzyme increased, pancreatitis. Methotrexate dosage: unknown. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4557780-4
Methotrexate side effect was reported by a Consumer or non-health professional from on Oct 29, 2003. Female patient, 55 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: dyspnoea, hypersensitivity, obliterative bronchiolitis, wheezing. Methotrexate dosage: 15 MG WEEKLY PO. During the same period patient was treated with ATENOLOL, WARFARIN, SIMVASTATIN, ROFECOXIB, NIFEDIPINE, OMEPRAZOLE. Patient recovered.

Methotrexate Side Effects Report #5494656-2
Methotrexate side effect was reported by a Pharmacist from UNITED STATES on Oct 23, 2007. Female patient, 54 years of age, weighting 273.4 lb, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: asthenia, chest pain , cough, dyspnoea, dyspnoea exertional, sensation of pressure. Methotrexate dosage: 25MG WEEKLY PO. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4635457-4
Methotrexate side effect was reported by a Consumer or non-health professional from on Mar 24, 2005. Female patient, 54 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: dyspnoea, lupus-like syndrome, pleural effusion, pleuritic pain, systemic lupus erythematosus, treatment noncompliance. Methotrexate dosage: 20 MG WEEKLY SC. During the same period patient was treated with PREDNISONE, REMICADE, ACIPHEX, PREMARIN, FOLIC ACID, CALCIUM GLUCONATE, VITAMIN D. Patient was hospitalized. Patient recovered.


Methotrexate Side Effects Report #5782953-2
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on June 19, 2008. Female patient, 51 years of age, weighting 152.0 lb, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: aspiration, cardiac failure congestive, dyspnoea, impaired work ability, lung disorder, oedema peripheral, oesophageal haemorrhage, oxygen saturation decreased, pneumonia . Methotrexate dosage: unknown. During the same period patient was treated with HUMIRA. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5055359-1
Methotrexate side effect was reported by a Consumer or non-health professional from KOREA, DEMOCRATIC PEOPLE'S REPUBLIC OF on July 07, 2006. Female patient, 46 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: anaplastic large cell lymphoma t- and null-cell types, ascites, costovertebral angle tenderness, dyspnoea, haemoglobin decreased, hepatosplenomegaly, lymphadenopathy, lymphadenopathy mediastinal, pleural effusion. Methotrexate dosage: unknown. During the same period patient was treated with FOLIC ACID, SULFASALAZINE, HYDROXYCHLOROQUINE SULPHATE. Patient recovered.

Methotrexate Side Effects Report #5108681-4
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Sept 06, 2006. Female patient, 46 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: ascites, costovertebral angle tenderness, dyspnoea, haemoglobin decreased, hepatosplenomegaly, lymphadenopathy, lymphoma , pleural effusion, red blood cell sedimentation rate increased. Methotrexate dosage: SEE TEXT (SEE TEXT, 7.5 TO 12.5 MG/WEEK), PO. During the same period patient was treated with SULFASALAZINE, HYDROXYCHLOROQUINE SULPHATE, SULINDAC, PREDNISOLONE, FOLIC ACID. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4683368-0
Methotrexate side effect was reported by a Pharmacist from on June 06, 2005. Female patient, 46 years of age, weighting 141.5 lb, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: dyspnoea, hypoxia, pneumonia , pulmonary toxicity. Methotrexate dosage: 10 MG WEEKLY ORAL. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4551310-9
Methotrexate side effect was reported by a Consumer or non-health professional from on Dec 28, 2004. Female patient, 35 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: blood beta-d-glucan increased, blood immunoglobulin g decreased, blood lactate dehydrogenase increased, c-reactive protein increased, cd4/cd8 ratio increased, cough, crackles lung, dyspnoea, hypoxia. Methotrexate dosage: 6 MG/WK UP TO 15 MG/WK (NR 1 IN 1 WK) PO. Patient was hospitalized. Patient recovered.


Methotrexate Side Effects Report #5205655-X
Methotrexate side effect was reported by a Pharmacist from UNITED STATES on Jan 05, 2007. Female patient, weighting 128.1 lb, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, asthenia, decreased appetite, dyspnoea, pancytopenia, platelet count increased, white blood cell count decreased. Methotrexate dosage: 7.5 MG PO Q WEEK. During the same period patient was treated with NIFEDIPINE, CALCIUM, DIGOXIN, ALENDRONATE, ISOSORBIDE, FUROSEMIDE, OMEPRAZOLE, PREDNISONE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5647427-8
Methotrexate side effect was reported by a Physician from NORWAY on Feb 20, 2008. Male patient was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: atrial flutter, cardiac failure congestive, dyspnoea, hepatocellular injury, renal function test abnormal. Methotrexate dosage: unknown. During the same period patient was treated with HUMIRA, PREDNISOLONE, PLAQUENIL, CELEBRA. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4579147-5
Methotrexate side effect was reported by a Pharmacist from on June 25, 2004. Female patient was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: accidental overdose, dyspnoea, platelet count decreased, thrombocytopenia. Methotrexate dosage: 10MG DAILY, ORAL. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #6063501-9
Methotrexate side effect was reported by a Consumer or non-health professional from on Feb 02, 2009. Female patient, 48 years of age, was diagnosed with psoriatic arthropathy, lung infiltration and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: cough, disease progression, dyspnoea, dyspnoea exertional, fatigue, pleural effusion, pulmonary function test decreased, rheumatoid nodule, serology abnormal. Methotrexate dosage: unknown. During the same period patient was treated with BROAD SPECTRUM ANTIBIOTICS, PREDNISONE, AZATHIOPRINE, ASPIRIN. Patient recovered.

Methotrexate Side Effects Report #5829994-4
Methotrexate side effect was reported by a Consumer or non-health professional from SWITZERLAND on July 31, 2008. Male patient, 58 years of age, weighting 200.6 lb, was diagnosed with lymphoma , metastases to central nervous system and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abscess , blister, blood test abnormal, cardiac disorder, coma, diarrhoea haemorrhagic, dyspnoea, haemorrhage, hypophagia. Methotrexate dosage: unknown. Patient died on 07/13/2008.


Methotrexate Side Effects Report #4669233-3
Methotrexate side effect was reported by a Consumer or non-health professional from on Dec 08, 2004. Male patient, 36 years of age, was diagnosed with desmoid tumour and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: dyspnoea, nausea , pneumonitis, polyneuropathy. Methotrexate dosage: 50 MG WEEKLY IV. During the same period patient was treated with VINBLASTINE. Patient recovered.

Methotrexate Side Effects Report #4692323-6
Methotrexate side effect was reported by a Consumer or non-health professional from on June 01, 2005. Male patient, 71 years of age, was diagnosed with chronic lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: chest pain , dyspnoea, pneumonia , pulmonary embolism , pyrexia, respiratory failure. Methotrexate dosage: unknown. During the same period patient was treated with CYTARABINE, CORTICOSTERIODS. Patient died.

Methotrexate Side Effects Report #5210904-8
Methotrexate side effect was reported by a Health Professional from UNITED STATES on June 26, 2006. Female patient, 37 years of age, was diagnosed with choriocarcinoma, metastasis and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: dyspnoea, mucosal inflammation, nephropathy toxic, stomatitis. Methotrexate dosage: unknown. Patient recovered.

Methotrexate Side Effects Report #4831434-9
Methotrexate side effect was reported by a Health Professional from UNITED STATES on Nov 16, 2005. Male patient, weighting 182.3 lb, was diagnosed with central nervous system lymphoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: chills, confusional state, dyspnoea, fatigue, hypoxia, irritability, pancytopenia, pharyngolaryngeal pain, pneumonia . Methotrexate dosage: 8 MG/M2 DAY 1 AND 15 Q CYCLE IV DRIP. During the same period patient was treated with THIOTEPA. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5099434-4
Methotrexate side effect was reported by a Pharmacist from UNITED STATES on Sept 05, 2006. Female patient, 90 years of age, weighting 117.0 lb, was diagnosed with cardiac failure congestive and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: cough, diarrhoea, dyspnoea, malaise, pharyngolaryngeal pain, rash , stomatitis. Methotrexate dosage: 10 MG (4X 2.5 MG TAB) ONCE DAILY PO. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4846216-1
Methotrexate side effect was reported by a Consumer or non-health professional from BRAZIL on Nov 16, 2005. Female patient, 51 years of age, was diagnosed with breast cancer metastatic and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: chest pain , convulsion, dyspnoea, malaise. Methotrexate dosage: 65 MILLIGRAM INTRAVENOUS NOS. During the same period patient was treated with CYCLOPHOSPHAMIDE, FLUOROURACIL, CAPTOPRIL, PROPRANOLOL. Patient died.

Methotrexate Side Effects Report #4560243-3
Methotrexate side effect was reported by a Physician from on Jan 20, 2005. Female patient, 76 years of age, weighting 136.7 lb, was diagnosed with breast cancer  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: anaemia, asthenia, creatinine renal clearance decreased, dizziness , dyspnoea, hypotension, hypovolaemia, leukopenia, lung disorder. Methotrexate dosage: 40 MG/M2 IV DAY 1+8. During the same period patient was treated with FLUOROURACIL, CYCLOPHOSPHAMIDE, LEVOXYL, ZYPREXA, DEPAKOTE, PROTONIX, DITROPAN, ALBUTEROL. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4630855-7
Methotrexate side effect was reported by a Physician from on Apr 04, 2005. Female patient, 76 years of age, was diagnosed with breast cancer  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: anaemia, asthenia, blood creatinine increased, dizziness , dyspnoea, hypotension, hypovolaemia, leukopenia, lung disorder. Methotrexate dosage: 40 MG/M2 IV DAY 1%0. During the same period patient was treated with FLUOROURACIL, CYCLOPHOSPHAMIDE, LEVOXYL, ZYPREXA, DEPAKOTE, PROTONIX, DITROPAN, ALBUTEROL. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5164552-9
Methotrexate side effect was reported by a Health Professional from FRANCE on July 15, 2002. Female patient, 63 years of age, was diagnosed with breast cancer , ovarian cancer and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: acute myeloid leukaemia, anaemia, asthenia, dyspnoea, pancytopenia, petechiae. Methotrexate dosage: unknown. During the same period patient was treated with ENDOXAN, PARAPLATIN, TENIPOSIDE, ONCOVIN, FLUOROURACIL. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5475504-3
Methotrexate side effect was reported by a Pharmacist from UNITED STATES on Sept 21, 2007. Female patient, child 12 years of age, was diagnosed with bone sarcoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: dyspnoea, infusion related reaction, lung disorder, urticaria. Methotrexate dosage: unknown. Patient recovered.


Methotrexate Side Effects Report #5664310-2
Methotrexate side effect was reported by a Consumer or non-health professional from JAPAN on Mar 07, 2008. Male patient, 54 years of age, was diagnosed with bone marrow transplant , engraftment syndrome and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: chest x-ray abnormal, dyspnoea, endotracheal intubation, engraftment syndrome, extubation, gait disturbance, haemoptysis, hypoxia, mechanical ventilation. Methotrexate dosage: unknown. During the same period patient was treated with CYCLOSPORINE, CYCLOPHOSPHAMIDE, METHYLPREDNISOLONE. Patient died.

Methotrexate Side Effects Report #4623465-9
Methotrexate side effect was reported by a Health Professional from on Mar 21, 2005. Female patient, 77 years of age, was diagnosed with b-cell lymphoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: c-reactive protein increased, cardiac murmur, dermatitis bullous, dyspnoea, oxygen saturation decreased, pancytopenia, pleural effusion, purulence, pyrexia. Methotrexate dosage: 15 MG, OD, IT. During the same period patient was treated with ONCOVIN, PREDNISONE, ACETAMINOPHEN. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5242864-8
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Feb 02, 2007. Female patient, 78 years of age, was diagnosed with arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: dyspnoea. Methotrexate dosage: 10 MG;WEEKLY;ORAL. During the same period patient was treated with ATENOLOL, AMLODIPINE, SIMVASTATIN, PREDNISONE ACETATE, DEXTROPROPOXYPHENE, DIAZEPAM. Patient recovered.

Methotrexate Side Effects Report #4883657-0
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Jan 17, 2006. Female patient, 74 years of age, weighting 113.0 lb, was diagnosed with arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: dyspnoea, hyperhidrosis, lung disorder, therapeutic agent toxicity, x-ray abnormal. Methotrexate dosage: unknown. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4902410-2
Methotrexate side effect was reported by a Consumer or non-health professional from JAPAN on Jan 23, 2006. Female patient, 69 years of age, was diagnosed with arthralgia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: antinuclear antibody positive, arthralgia, blood lactate dehydrogenase increased, cough, dyspnoea, haematocrit decreased, haematuria, haemoglobin decreased, hypoxia. Methotrexate dosage: unknown. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5676696-3
Methotrexate side effect was reported by a Pharmacist from UNITED STATES on Mar 21, 2008. Male patient, 17 years of age, weighting 135.1 lb, was diagnosed with acute lymphocytic leukaemia recurrent and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: angioedema, blood creatinine increased, dyspnoea, paraesthesia. Methotrexate dosage: 5 MG/M2 X 1 IV. During the same period patient was treated with LEUCOVORIN. Patient was hospitalized and became disabled. Patient recovered.

Methotrexate Side Effects Report #6072068-0
Methotrexate side effect was reported by a Pharmacist from UNITED STATES on Feb 05, 2009. Male patient, 49 years of age, weighting 222.7 lb, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: confusional state, delirium, dyspnoea, hypoxia, pancytopenia, pneumonitis, pulmonary toxicity, pyrexia. Methotrexate dosage: 40MG WEEKLY PO. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5451280-5
Methotrexate side effect was reported by a Pharmacist from UNITED STATES on Sept 11, 2007. Male patient, weighting 211.0 lb, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: asthenia, dysphagia, dyspnoea. Methotrexate dosage: unknown. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5027795-0
Methotrexate side effect was reported by a Physician from UNITED STATES on June 14, 2006. Female patient, 82 years of age, weighting 186.0 lb, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: dyspnoea, fatigue, lung infiltration, pneumonitis, pyrexia. Methotrexate dosage: 25 MG SC WEEKLY. During the same period patient was treated with REMICADE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4877434-4
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Dec 27, 2005. Female patient, 81 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: dyspnoea, mucosal inflammation, pancytopenia, sepsis . Methotrexate dosage: 25 MG PER WEEK , PO. During the same period patient was treated with CARBIMAZOLE, CELECOXIB, FOLIC ACID, OMEPRAZOLE, ALENDRONATE. Patient was hospitalized. Patient died.


Methotrexate Side Effects Report #5012299-1
Methotrexate side effect was reported by a Physician from UNITED KINGDOM on May 17, 2006. Female patient, 81 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: dyspnoea, mucosal inflammation, pancytopenia, sepsis . Methotrexate dosage: 25 MG PER WEEK, PO. During the same period patient was treated with CARBIMAZOLE, CELECOXIB, FOLIC ACID, OMEPRAZOLE, ALENDRONATE. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #5107662-4
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Sept 11, 2006. Male patient, 75 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: acute myocardial infarction, alveolitis, cardiogenic shock, dyspnoea, infection , pneumonitis. Methotrexate dosage: 10 MG - 1XW - PO. During the same period patient was treated with OMEPRAZOLE, DICLOFENAC, FOLIC ACID, PREDNISOLONE, ATORVASTATIN, PERINDOPRIL ERBUMINE, LEFLUNOMIDE. Patient was hospitalized. Patient died on 01/20/2005.

Methotrexate Side Effects Report #4823420-X
Methotrexate side effect was reported by a Health Professional from UNITED KINGDOM on Oct 24, 2005. Male patient, 75 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: acute myocardial infarction, alveolitis, cardiac disorder, cardiogenic shock, dyspnoea, infection , respiratory disorder. Methotrexate dosage: 10 MG WEEKLY PO. During the same period patient was treated with OMEPRAZOLE, DICLOFENAC, FOLIC ACID, PREDNISOLONE, ATORVASTATIN CALCIUM, PERINDOPRIL, LEFLUNOMIDE. Patient was hospitalized. Patient died on 01/20/2005.

Methotrexate Side Effects Report #4948421-2
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Feb 27, 2006. Male patient, 75 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alveolitis, dyspnoea, pulmonary function test decreased. Methotrexate dosage: 10 MG WEEKLY; PO. During the same period patient was treated with OMEPRAZOLE, DICLOFENAC, FOLIC ACID, PREDNISOLONE, ATORVASTATIN CALCIUM, PERINDOPRIL, LEFLUNOMIDE. Patient was hospitalized. Patient died on 01/20/2005.

Methotrexate Side Effects Report #4770792-0
Methotrexate side effect was reported by a Health Professional from UNITED KINGDOM on Aug 30, 2005. Male patient, 69 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: acute myeloid leukaemia, dyspnoea, lethargy, pancytopenia. Methotrexate dosage: 12.5 MG WEEKLY PO. During the same period patient was treated with CALCICHEW, ASPIRIN, PREDNISOLONE, FUROSEMIDE, ALENDRONIC, MESALAMINE, LEUCOVORIN CALCIUM. Patient died.

Methotrexate Side Effects Report #4877304-1
Methotrexate side effect was reported by a Consumer or non-health professional from on Dec 27, 2005. Male patient, 69 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: acute myeloid leukaemia, dyspnoea, lethargy, pancytopenia. Methotrexate dosage: 12.5 MG PER WEEK (NR), PO. During the same period patient was treated with CALCICHEW, ASPIRIN, PREDNISOLONE, FUROSEMIDE, ALENDRONATE, MESALAMINE, LEUCOVORIN CALCIUM. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #5012023-2
Methotrexate side effect was reported by a Physician from UNITED KINGDOM on May 17, 2006. Male patient, 69 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: dyspnoea, lethargy, pancytopenia. Methotrexate dosage: 12.5 MG PER WEEK, PO. During the same period patient was treated with CALCICHEW, ASPIRIN, PREDNISOLONE, FRUSEMIDE, ALENDRONATE, MESALAMINE, LEUCOVORIN CALCIUM. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #5663641-X
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Feb 29, 2008. Female patient, 67 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: dyspnoea, wheezing. Methotrexate dosage: unknown. During the same period patient was treated with ENBREL, BENDROFLUAZIDE, FOLIC ACID, LACIDIPINE. Patient recovered.

Methotrexate Side Effects Report #5855352-2
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 19, 2008. Male patient, 28 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: dyspnoea, headache , nausea , pyrexia, vertigo. Methotrexate dosage: unknown. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5297650-X
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Mar 27, 2007. Male patient was treated with Methotrexate. After drug was administered, patient experienced the following side effects: dyspnoea. Methotrexate dosage: 20 MG WEEKLY PO. Patient recovered.


Methotrexate Side Effects Report #5739314-1
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on May 12, 2008. Female patient, weighting 175.3 lb, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: blood pressure increased, dyspnoea, jugular vein thrombosis, tachycardia. Methotrexate dosage: 1600 MG. During the same period patient was treated with RITUXIMAB, LEUCOVORIN CALCIUM. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5848279-3
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 14, 2008. Male patient, weighting 180.3 lb, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: csf glucose decreased, csf protein increased, csf white blood cell count positive, dyspnoea, headache , hydrocephalus , nausea , pulmonary congestion, pyrexia. Methotrexate dosage: 12500 MG. During the same period patient was treated with RITUXIMAB, DEXAMETHOSOME. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5920552-X
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Oct 15, 2008. Male patient, weighting 162.3 lb, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: csf glucose decreased, csf protein increased, csf white blood cell count increased, dyspnoea, headache , hydrocephalus , lung infiltration, meningeal disorder, nausea . Methotrexate dosage: unknown. During the same period patient was treated with RITUXIMAB, TEMOZOLOMIDE, DILAUDID, VANCOMYCIN HYDROCHLORIDE, PHENERGAN, XANAX, INSULIN. Patient was hospitalized. Patient recovered.