Methotrexate and asthenia Patient Reports February 11, 2012

Methotrexate Side Effects Report #5995345-8
Methotrexate side effect was reported by a Consumer or non-health professional from GERMANY on Dec 02, 2008. Female patient, 82 years of age, was diagnosed with rheumatoid arthritis

and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: asthenia, cd4 lymphocytes decreased, cerebellar syndrome, dysarthria, gait disturbance, hyporeflexia, lymphopenia, neurotoxicity, normochromic normocytic anaemia. Methotrexate dosage: 15 MG WEEKLY. During the same period patient was treated with PREDNISONE, FOLIC ACID. Patient recovered.

Methotrexate Side Effects Report #4923829-X
Methotrexate side effect was reported by a Pharmacist from UNITED STATES on Feb 24, 2006. Female patient, 79 years of age, weighting 156.5 lb, was diagnosed with rheumatoid arthritis

and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: anuria, asthenia, brain natriuretic peptide increased, chills, dyspnoea, fatigue, immunosuppression, lung infiltration, lung injury. Methotrexate dosage: 10 MG WEEKLY IM. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #6027447-4
Methotrexate side effect was reported by a Health Professional from LITHUANIA on Dec 23, 2008. Female patient, 76 years of age, was diagnosed with rheumatoid arthritis

, connective tissue disorder

and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: asthenia, depressed level of consciousness, dyspnoea, haemangioma, hypotension, keratitis, pulmonary fibrosis

, pyrexia, septic shock. Methotrexate dosage: unknown. During the same period patient was treated with AZATHIOPRINE, PREDNISOLONE, PLAQUENIL. Patient was hospitalized. Patient died on 08/20/2008.

Methotrexate Side Effects Report #6056304-2
Methotrexate side effect was reported by a Health Professional from LITHUANIA on Jan 16, 2009. Female patient, 76 years of age, was diagnosed with rheumatoid arthritis

, connective tissue disorder

and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, asthenia, depressed level of consciousness, diffuse large b-cell lymphoma, dyspnoea, haemangioma of liver, keratitis, leukocytoclastic vasculitis, localised infection. Methotrexate dosage: unknown. During the same period patient was treated with AZATHIOPRINE, PREDNISOLONE, PLAQUENIL. Patient was hospitalized. Patient died on 08/20/2008.

Methotrexate Side Effects Report #5120436-3
Methotrexate side effect was reported by a Consumer or non-health professional from SWITZERLAND on Sept 22, 2006. Female patient, 74 years of age, was diagnosed with rheumatoid arthritis

and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: aspergillosis, asthenia, candidiasis, cardiovascular insufficiency, dyspnoea, enterococcal infection, hepatic enzyme increased, pneumocystis jiroveci pneumonia. Methotrexate dosage: unknown. During the same period patient was treated with PREDNISONE, NSAID, IMUREK. Patient died.

Methotrexate Side Effects Report #5405005-X
Methotrexate side effect was reported by a Physician from UNITED STATES on July 20, 2007. Male patient, 72 years of age, was diagnosed with rheumatoid arthritis

and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: anorexia, asthenia, atelectasis, ecchymosis, fatigue, histoplasmosis disseminated, pancytopenia, pyrexia, speech disorder. Methotrexate dosage: 15 MG, WEEKLY, ORAL. During the same period patient was treated with PREDNISONE. Patient recovered.

Methotrexate Side Effects Report #4616631-X
Methotrexate side effect was reported by a Consumer or non-health professional from on Mar 02, 2005. Male patient, 72 years of age, was diagnosed with rheumatoid arthritis

and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: anorexia, asthenia, biopsy bone marrow abnormal, ecchymosis, fatigue, histoplasmosis disseminated, opportunistic infection, pancytopenia, speech disorder. Methotrexate dosage: 15 MG WEEKLY PO. During the same period patient was treated with PREDNISOLONE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4806432-1
Methotrexate side effect was reported by a Pharmacist from UNITED STATES on Oct 19, 2005. Male patient, 69 years of age, weighting 187.0 lb, was diagnosed with rheumatoid arthritis

and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain upper, asthenia, interstitial lung disease, metastatic neoplasm, oxygen saturation decreased, pulmonary function test abnormal. Methotrexate dosage: 8 TABLETS-20MG- EVERY WEEK PO (DURATION: ALMOST 3 YEARS). During the same period patient was treated with CITALOPRAM, DIGOXIN, DOCUSATE, ENOXAPARIN, FLUVASTATIN, FUROSEMIDE, NITROGLYCERIN, OMEPRAZOLE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4737744-8
Methotrexate side effect was reported by a Physician from on July 22, 2005. Female patient, 68 years of age, was diagnosed with rheumatoid arthritis

and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: anorexia, asthenia, diastolic dysfunction, hypoalbuminaemia, hypoxia, leukopenia, lymphopenia, normochromic normocytic anaemia, oedema peripheral. Methotrexate dosage: unknown. During the same period patient was treated with PREDNISONE. Patient recovered.

Methotrexate Side Effects Report #6022437-X
Methotrexate side effect was reported by a Consumer or non-health professional from TURKEY on Dec 15, 2008. Male patient, 64 years of age, was diagnosed with rheumatoid arthritis

and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, asthenia, blood albumin decreased, blood urea increased, c-reactive protein increased, decreased appetite, hypotension, jaundice

. Methotrexate dosage: 2.5 MG TWICE DAILY. During the same period patient was treated with MOXIFLOXACIN, METHYLPREDNISOLONE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #6056013-X
Methotrexate side effect was reported by a Consumer or non-health professional from TURKEY on Jan 15, 2009. Male patient, 64 years of age, was diagnosed with rheumatoid arthritis

and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, asthenia, blood lactate dehydrogenase increased, decreased appetite, epistaxis, hypotension, incorrect dose administered, jaundice

. Methotrexate dosage: 2.5 MG TWICE DAILY ORAL. During the same period patient was treated with MOXIFLOXACIN, METHYLPREDNISOLONE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4579117-7
Methotrexate side effect was reported by a Consumer or non-health professional from on Dec 16, 2003. Male patient, 60 years of age, was diagnosed with rheumatoid arthritis

and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: asthenia, chest pain

, chills, cough, dyspnoea, fatigue, leukocytosis, pneumonia

, pneumonitis. Methotrexate dosage: 12.5 MG 1X PER 1 WK, ORAL. During the same period patient was treated with ENBREL, PREDNISONE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5494656-2
Methotrexate side effect was reported by a Pharmacist from UNITED STATES on Oct 23, 2007. Female patient, 54 years of age, weighting 273.4 lb, was diagnosed with rheumatoid arthritis

and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: asthenia, chest pain

, cough, dyspnoea, dyspnoea exertional, sensation of pressure. Methotrexate dosage: 25MG WEEKLY PO. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4982458-2
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Apr 04, 2006. Female patient, 48 years of age, was diagnosed with rheumatoid arthritis

and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal discomfort, alanine aminotransferase increased, aleukaemic leukaemia, anaemia, anorexia, aplastic anaemia, aspartate aminotransferase increased, asthenia, band neutrophil percentage increased. Methotrexate dosage: 10 MG PER WEEK (1 IN 1 WK), PO. During the same period patient was treated with PREDNISONE, PRIOXICAM, FOLIC ACID, CALCIUM, VITAMIN. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4998636-2
Methotrexate side effect was reported by a Health Professional from TURKEY on Apr 27, 2006. Female patient, 22 years of age, was diagnosed with rheumatoid arthritis

and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: asthenia, blood albumin decreased, blood calcium decreased, blood phosphorus decreased, blood urea decreased, body temperature increased, breast atrophy, breast mass, calciphylaxis. Methotrexate dosage: 7.5 MG, QW, ORAL. During the same period patient was treated with PREDNISOLONE. Patient died.

Methotrexate Side Effects Report #5205655-X
Methotrexate side effect was reported by a Pharmacist from UNITED STATES on Jan 05, 2007. Female patient, weighting 128.1 lb, was diagnosed with rheumatoid arthritis

and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, asthenia, decreased appetite, dyspnoea, pancytopenia, platelet count increased, white blood cell count decreased. Methotrexate dosage: 7.5 MG PO Q WEEK. During the same period patient was treated with NIFEDIPINE, CALCIUM, DIGOXIN, ALENDRONATE, ISOSORBIDE, FUROSEMIDE, OMEPRAZOLE, PREDNISONE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4733735-1
Methotrexate side effect was reported by a Consumer or non-health professional from on July 12, 2005. Female patient was diagnosed with rheumatoid arthritis

, bronchopneumonia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: anaemia macrocytic, anorexia, asthenia, bronchopneumonia, diarrhoea, folate deficiency, gastritis atrophic, intestinal villi atrophy, stomatitis. Methotrexate dosage: unknown. During the same period patient was treated with CEFTRIAXONE. Patient recovered.

Methotrexate Side Effects Report #5249304-3
Methotrexate side effect was reported by a Consumer or non-health professional from GERMANY on Feb 14, 2007. Female patient, 56 years of age, was diagnosed with prophylaxis and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: asthenia, blood glucose increased, coma, extensor plantar response, eyelid ptosis, hypertension, leukoencephalopathy, mucosal inflammation, phagocytosis. Methotrexate dosage: 3 DOSES OF 15 MG. During the same period patient was treated with FLUDARABINE, CARMUSTINE, MELPHALAN, MYCOPHENOLATE MOFETIL. Patient died.

Methotrexate Side Effects Report #5481797-9
Methotrexate side effect was reported by a Consumer or non-health professional from on Oct 02, 2007. Male patient, child 10 years of age, was diagnosed with osteosarcoma metastatic and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: altered state of consciousness, aplasia, asthenia, convulsion, encephalitis

, hypotension, neutropenia, pyrexia, rash vesicular. Methotrexate dosage: unknown. During the same period patient was treated with DOXORUBICIN. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4710999-1
Methotrexate side effect was reported by a Consumer or non-health professional from TURKEY on June 24, 2005. Male patient, 13 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abasia, arachnoiditis, asthenia, encopresis, hyporeflexia, malignant neoplasm progression, myelopathy, non-hodgkin's lymphoma, urinary incontinence

. Methotrexate dosage: 75 MG TOTAL IT. During the same period patient was treated with CYTOSINE ARABINOSIDE, PREDNISOLONE. Patient recovered.

Methotrexate Side Effects Report #6137467-7
Methotrexate side effect was reported by a Physician from UNITED KINGDOM on Mar 14, 2009. Female patient, 18 years of age, was diagnosed with malignant fibrous histiocytoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: asthenia, dysphasia, headache

, hemiparesis. Methotrexate dosage: unknown. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4742549-8
Methotrexate side effect was reported by a Health Professional from UNITED STATES on July 28, 2005. Male patient, 67 years of age, weighting 105.8 lb, was diagnosed with laryngeal cancer and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: asthenia, blood potassium increased, blood urea increased. Methotrexate dosage: 63 MG/ WEEK IV. Patient died on 07/06/2005.

Methotrexate Side Effects Report #4714480-5
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on June 29, 2005. Male patient, child 11 years of age, was diagnosed with juvenile arthritis and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: asthenia, malaise, rheumatoid arthritis

, swelling, vomiting, weight increased. Methotrexate dosage: unknown. During the same period patient was treated with CORTICOSTEROID. Patient recovered.

Methotrexate Side Effects Report #5069654-3
Methotrexate side effect was reported by a Health Professional from UNITED STATES on Aug 02, 2006. Female patient, 19 years of age, weighting 135.0 lb, was diagnosed with ectopic pregnancy and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abortion spontaneous, asthenia, asthma

, chemical injury, condition aggravated, cough, haematocrit decreased, haemoglobin decreased. Methotrexate dosage: 3.70 ML X1 IM. Patient recovered.

Methotrexate Side Effects Report #6023402-9
Methotrexate side effect was reported by a Consumer or non-health professional from FRANCE on Dec 26, 2008. Female patient, 53 years of age, was diagnosed with dermatomyositis, metastasis and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain

, asthenia, pneumatosis intestinalis, pneumoperitoneum. Methotrexate dosage: unknown. During the same period patient was treated with FLUOROURACIL, VINORELBINE, PREDNISONE, METHYLPREDNISOLONE SUCCINATE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5110814-0
Methotrexate side effect was reported by a Physician from KENYA on Sept 05, 2006. Male patient, child 8 years of age, was diagnosed with burkitt's lymphoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: anorexia, arthralgia, asthenia, blood creatinine decreased, blood potassium decreased, convulsion, dehydration, diarrhoea, haemoglobin decreased. Methotrexate dosage: 20 MG/M2 PU. During the same period patient was treated with VINCRISTINE, CYCLOPHOSPHAMIDE, PREDNISOLONE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4953308-5
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Mar 09, 2006. Female patient, 65 years of age, was diagnosed with burkitt's lymphoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: asthenia, blood osmolarity decreased, blood uric acid decreased, confusional state, hyponatraemia, lethargy, polyuria. Methotrexate dosage: unknown. During the same period patient was treated with MEGACE, CLONAZEPAM, OMEPRAZOLE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5028166-3
Methotrexate side effect was reported by a Physician from UNITED STATES on May 30, 2006. Female patient, 65 years of age, was diagnosed with burkitt's lymphoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: asthenia, blood osmolarity decreased, blood uric acid decreased, confusional state, hyponatraemia, lethargy, urine output increased. Methotrexate dosage: unknown. During the same period patient was treated with MEGACE, CLONAZEPAM, OMEPRAZOLE, PHENYTOIN. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5730267-9
Methotrexate side effect was reported by a Consumer or non-health professional from ITALY on Apr 24, 2008. Female patient, 84 years of age, was diagnosed with breast cancer

and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: anaemia, asthenia, blood bilirubin increased, bone marrow toxicity, diarrhoea, haemoglobin decreased, hyperkalaemia, intestinal obstruction, leukopenia. Methotrexate dosage: 2.5 MG TWICE A DAY, 2 DAYS WEEKLY ORAL. During the same period patient was treated with CYCLOPHOSPHAMIDE. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #4560243-3
Methotrexate side effect was reported by a Physician from on Jan 20, 2005. Female patient, 76 years of age, weighting 136.7 lb, was diagnosed with breast cancer

and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: anaemia, asthenia, creatinine renal clearance decreased, dizziness

, dyspnoea, hypotension, hypovolaemia, leukopenia, lung disorder. Methotrexate dosage: 40 MG/M2 IV DAY 1+8. During the same period patient was treated with FLUOROURACIL, CYCLOPHOSPHAMIDE, LEVOXYL, ZYPREXA, DEPAKOTE, PROTONIX, DITROPAN, ALBUTEROL. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4630855-7
Methotrexate side effect was reported by a Physician from on Apr 04, 2005. Female patient, 76 years of age, was diagnosed with breast cancer

and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: anaemia, asthenia, blood creatinine increased, dizziness

, dyspnoea, hypotension, hypovolaemia, leukopenia, lung disorder. Methotrexate dosage: 40 MG/M2 IV DAY 1%0. During the same period patient was treated with FLUOROURACIL, CYCLOPHOSPHAMIDE, LEVOXYL, ZYPREXA, DEPAKOTE, PROTONIX, DITROPAN, ALBUTEROL. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5164552-9
Methotrexate side effect was reported by a Health Professional from FRANCE on July 15, 2002. Female patient, 63 years of age, was diagnosed with breast cancer

, ovarian cancer and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: acute myeloid leukaemia, anaemia, asthenia, dyspnoea, pancytopenia, petechiae. Methotrexate dosage: unknown. During the same period patient was treated with ENDOXAN, PARAPLATIN, TENIPOSIDE, ONCOVIN, FLUOROURACIL. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4724400-5
Methotrexate side effect was reported by a Consumer or non-health professional from GERMANY on July 08, 2005. Female patient, 16 years of age, was diagnosed with bone sarcoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: aphasia

, asthenia, dysarthria, dysphagia, neurotoxicity, somnolence. Methotrexate dosage: unknown. During the same period patient was treated with HYDROMORPHONE HYDROCHLORIDE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4844572-1
Methotrexate side effect was reported by a Health Professional from GERMANY on Nov 16, 2005. Female patient, 16 years of age, was diagnosed with bone sarcoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: aphasia

, asthenia, dysarthria, dysphagia, neurotoxicity, somnolence, therapeutic agent toxicity. Methotrexate dosage: 1200 MG/M2 PER_CYCLE IV. During the same period patient was treated with DILAUDID. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4902366-2
Methotrexate side effect was reported by a Health Professional from GERMANY on Jan 23, 2006. Female patient, 16 years of age, was diagnosed with bone sarcoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: aphasia

, asthenia, dysarthria, dysphagia, neurotoxicity, somnolence, therapeutic agent toxicity. Methotrexate dosage: 1200 MG/M2 PER_CYCLE IV. During the same period patient was treated with DILAUDID. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4958411-1
Methotrexate side effect was reported by a Health Professional from UNITED STATES on Mar 29, 2006. Female patient, weighting 90.39 lb, was diagnosed with bone sarcoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: aphasia

, areflexia, asthenia, hemiparesis, hypoaesthesia, paraesthesia. Methotrexate dosage: unknown. During the same period patient was treated with ONDANSETRON, DEXRAZOXANE, DEXAMETHASONE, LORAZEPAM, LEUCOVORIN. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5974970-4
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Nov 17, 2008. Female patient, 53 years of age, was diagnosed with b precursor type acute leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: asthenia, paraesthesia. Methotrexate dosage: unknown. During the same period patient was treated with CYTARABINE, CYCLOPHOSPHAMIDE, VINCRISTINE, DEXAMETHASONE. Patient recovered.

Methotrexate Side Effects Report #5656142-6
Methotrexate side effect was reported by a Health Professional from UNITED STATES on Feb 20, 2008. Male patient, child 12 years of age, was diagnosed with b precursor type acute leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: affect lability, asthenia, choreoathetosis, dysphasia, hemiparesis, movement disorder

, nuclear magnetic resonance imaging brain abnormal, toxic encephalopathy. Methotrexate dosage: unknown. Patient recovered.

Methotrexate Side Effects Report #5239604-5
Methotrexate side effect was reported by a Physician from TAIWAN, PROVINCE OF CHINA on Jan 27, 2007. Female patient, 33 years of age, was diagnosed with arthritis

and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: asthenia, bone marrow failure, chest discomfort, leukaemoid reaction, mucosal inflammation, no therapeutic response, oedema peripheral, respiratory distress, tachycardia. Methotrexate dosage: 5 MG WEEKLY. During the same period patient was treated with FOLIC ACID, PREDNISOLONE. Patient recovered.

Methotrexate Side Effects Report #5848056-3
Methotrexate side effect was reported by a Consumer or non-health professional from FRANCE on Aug 01, 2008. Female patient, 52 years of age, was diagnosed with ankylosing spondylitis

and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain

, arthralgia, asthenia, bedridden, chest pain

, chills, cough, cytomegalovirus infection

, interstitial lung disease. Methotrexate dosage: 15 MG WEEKLY, ORAL; DECREASED TO 10 MG WEEKLY. During the same period patient was treated with PREDNISONE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5933866-4
Methotrexate side effect was reported by a Health Professional from UNITED STATES on Oct 14, 2008. Female patient, 53 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: asthenia, demyelination, myelopathy, paraesthesia, wheelchair user. Methotrexate dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, VINCRISTINE, DEXAMETHASONE, CYTARABINE. Patient was hospitalized and became disabled. Patient recovered.

Methotrexate Side Effects Report #5956093-3
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Nov 03, 2008. Female patient, 53 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: asthenia, paraesthesia. Methotrexate dosage: unknown. During the same period patient was treated with CYTARABINE, CYCLOPHOSPHAMIDE, VINCRISTINE, DEXAMETHASONE. Patient recovered.

Methotrexate Side Effects Report #4711013-4
Methotrexate side effect was reported by a Consumer or non-health professional from TURKEY on June 24, 2005. Male patient, child 5 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abasia, arachnoiditis, asthenia, encopresis, hyporeflexia, myelopathy, urinary incontinence

, urinary retention, urinary tract infection

. Methotrexate dosage: 140 MG TOTAL IT. During the same period patient was treated with CYTOSINE ARABINOSIDE, PREDNISOLONE. Patient recovered.

Methotrexate Side Effects Report #4824752-1
Methotrexate side effect was reported by a Physician from GERMANY on Oct 28, 2005. Female patient, 48 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: asthenia, blood albumin decreased, diabetic neuropathy, faecal incontinence, inflammation, leukocytosis, myelopathy, oedema, paraparesis. Methotrexate dosage: 15 MG PER_CYCLE IT. During the same period patient was treated with CYTARABINE, CYCLOPHOSPHAMIDE, DEXAMETHASONE, ELSPAR, VINCRISTINE, DAUNORUBICIN, PREDNISOLONE, MERCAPTOPURINE. Patient recovered.

Methotrexate Side Effects Report #4870602-7
Methotrexate side effect was reported by a Consumer or non-health professional from on Dec 13, 2005. Male patient, child 4 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: adhesion

, arachnoiditis, asthenia, csf protein increased, myelopathy, neurological symptom, somatosensory evoked potentials abnormal, urinary incontinence

, urinary retention. Methotrexate dosage: unknown. During the same period patient was treated with CYTARABINE, PREDNISOLONE. Patient died.

Methotrexate Side Effects Report #5258086-0
Methotrexate side effect was reported by a Consumer or non-health professional from JAPAN on Feb 28, 2007. Male patient, 23 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: asthenia, headache

, meningioma, nausea

, oedema, papilloedema. Methotrexate dosage: unknown. During the same period patient was treated with VINCRISTINE, PREDNISOLONE, MERCAPTOPURINE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4544937-1
Methotrexate side effect was reported by a Physician from on Dec 20, 2004. Female patient, 15 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: aphasia

, asthenia, neurotoxicity. Methotrexate dosage: unknown. Patient recovered.

Methotrexate Side Effects Report #4551983-0
Methotrexate side effect was reported by a Consumer or non-health professional from on Dec 29, 2004. Female patient, 15 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: arthropathy, asthenia, cerebral infarction, coordination abnormal, facial nerve disorder, facial paresis, neurotoxicity. Methotrexate dosage: 10500 MG, IV. During the same period patient was treated with MERCAPTOPURINE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5886987-9
Methotrexate side effect was reported by a Consumer or non-health professional from on Sept 11, 2008. Male patient, 13 years of age, was diagnosed with acute lymphocytic leukaemia, gastroenteritis

, febrile neutropenia, erythema, dysphagia, pyrexia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: asthenia, chest pain

, diarrhoea haemorrhagic, dysphagia, erythema, febrile neutropenia, gastroenteritis

, nausea

, pyrexia. Methotrexate dosage: unknown. During the same period patient was treated with CEFTRIAXONE, TEICOPLANIN, MOISTURIZERS, AMPHOTERICIN B, VENOGLOBULIN, CIPROFLOXACIN. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5909494-3
Methotrexate side effect was reported by a Consumer or non-health professional from TURKEY on Sept 24, 2008. Male patient, 13 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: anal ulcer, asthenia, diarrhoea haemorrhagic, erythema, gastroenteritis

, haemoglobin decreased, lip ulceration, mouth ulceration, platelet count decreased. Methotrexate dosage: unknown. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4630310-4
Methotrexate side effect was reported by a Physician from on Apr 05, 2005. Female patient, child 12 years of age, weighting 103.6 lb, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: asthenia, cranial nerve paralysis. Methotrexate dosage: 15 MG INTRATHECALLY 5 GRAM/M2 WK 24HRS. During the same period patient was treated with MERCAPTOPURINE, VINCRISTINE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5663422-7
Methotrexate side effect was reported by a Consumer or non-health professional from KOREA, REPUBLIC OF on Feb 28, 2008. Female patient, child 10 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: areflexia, asthenia, dysarthria, guillain-barre syndrome

, leukoencephalopathy, neuropathy peripheral, paralysis

, respiratory disorder. Methotrexate dosage: unknown. During the same period patient was treated with VINCRISTINE, ASPARAGINASE. Patient recovered.

Methotrexate Side Effects Report #5451280-5
Methotrexate side effect was reported by a Pharmacist from UNITED STATES on Sept 11, 2007. Male patient, weighting 211.0 lb, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: asthenia, dysphagia, dyspnoea. Methotrexate dosage: unknown. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4714821-9
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on July 14, 2005. Female patient, weighting 50.04 lb, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abnormal behaviour, asthenia, convulsion, depressed level of consciousness, electroencephalogram abnormal, encephalopathy, full blood count abnormal, hypotonia, loss of consciousness. Methotrexate dosage: 12 MG GIVEN ON 6/23/2005 (DAY 8). During the same period patient was treated with VINCRISTINE, DEXAMETHASONE, PEG ASPARAGINASE, CYTARABINE. Patient recovered.

Methotrexate Side Effects Report #5610663-0
Methotrexate side effect was reported by a Pharmacist from UNITED STATES on Jan 31, 2008. Male patient, 85 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: asthenia, confusional state, memory impairment. Methotrexate dosage: unknown. Patient recovered.

Methotrexate Side Effects Report #4695173-X
Methotrexate side effect was reported by a Consumer or non-health professional from on June 06, 2005. Female patient, 66 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: asthenia, cerebellar syndrome, gait disturbance, nausea

. Methotrexate dosage: 15 MILLIGRAM INTRATHECAL. During the same period patient was treated with CYTARABINE, MABTHERA, IMMUNOGLOBULIN NORMAL, CYCLOPHOSPHAMIDE, DOXORUBICIN, VINDESINE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4621520-0
Methotrexate side effect was reported by a Health Professional from on June 14, 2004. Female patient, 55 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: asthenia. Methotrexate dosage: unknown. During the same period patient was treated with ETANERCEPT. Patient recovered.

Methotrexate Side Effects Report #4550116-4
Methotrexate side effect was reported by a Consumer or non-health professional from on Nov 11, 2004. Female patient, 53 years of age, was diagnosed with rheumatoid arthritis

and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, asthenia, hypotension, lobar pneumonia, pharyngolaryngeal pain, respiratory failure, sepsis

, vomiting. Methotrexate dosage: 15 MG WEEKLY SC. During the same period patient was treated with PREDNISONE, ENBREL, FOLIC ACID, PEPCID, ACTONEL, PILCARPINE HDYROCHLORIDE, INSULIN GLARGINE, INSULIN ASPART. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4920111-1
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Feb 06, 2006. Male patient, 21 years of age, weighting 158.7 lb, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: asthenia, dysphagia, dysphasia, facial paresis, hypoaesthesia, paraesthesia. Methotrexate dosage: 12.5 MG DAILY IT. During the same period patient was treated with TAZOCIN, GENTAMICIN, RASBURICASE, CORSODYL, OMEPRAZOLE, GRANISETRON, VANCOMYCIN, CIPROFLOXACIN. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4903364-5
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Feb 06, 2006. Male patient, 18 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: asthenia, confusional state, disease progression, eyelid ptosis, facial paresis, hypersomnia, incorrect dose administered, leukoencephalopathy, speech disorder. Methotrexate dosage: unknown. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5228751-X
Methotrexate side effect was reported by a Consumer or non-health professional from GERMANY on Jan 19, 2007. Female patient, 14 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, arthralgia, aspartate aminotransferase increased, asthenia, atonic urinary bladder, blood immunoglobulin a decreased, blood immunoglobulin m decreased, bone marrow failure, gait disturbance. Methotrexate dosage: 12 MG PER_CYCLE IT. During the same period patient was treated with CYTARABINE, PREDNISOLONE, IBUPROFEN. Patient recovered.

Methotrexate Side Effects Report #5046109-3
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on July 07, 2006. Male patient, weighting 109.1 lb, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: asthenia, cerebral ischaemia, cerebrovascular accident, hypoaesthesia, infarction, muscular weakness. Methotrexate dosage: unknown. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5052426-3
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on July 14, 2006. Male patient, weighting 109.1 lb, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: asthenia, cerebral infarction, cerebral ischaemia, cerebrovascular accident, muscular weakness. Methotrexate dosage: 45 MG. During the same period patient was treated with VINCRISTINE SULPHATE, CYTARABINE, DOXORUBICIN HYDROCHLORIDE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5429283-6
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 27, 2007. Male patient, weighting 184.7 lb, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: agitation, altered state of consciousness, aphasia

, apnoea, asthenia, confusional state, delirium, dysarthria, dysphagia. Methotrexate dosage: 20515 MG. During the same period patient was treated with LEUCOVORIN CALCIUM, MERCAPTOPURINE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4636435-1
Methotrexate side effect was reported by a Consumer or non-health professional from on Apr 13, 2005. Male patient, weighting 198.4 lb, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: aphasia

, asthenia, headache

, incontinence, pancytopenia, pyrexia. Methotrexate dosage: unknown. During the same period patient was treated with PREDNISONE, CYTOXAN, THIOGUANINE. Patient recovered.

Methotrexate and asthenia

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Methotrexate and asthenia Patient Reports February 11, 2012

side effects of Methotrexate