Methotrexate and aspartate aminotransferase increased Patient Reports February 11, 2012

Methotrexate Side Effects Report #5747264-X
Methotrexate side effect was reported by a Physician from FRANCE on May 05, 2008. Female patient, 62 years of age, was diagnosed with systemic lupus erythematosus and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, ascites, aspartate aminotransferase increased, bilirubin conjugated increased, blood albumin increased, hepatic necrosis, hepatic steatosis, hepatitis infectious mononucleosis. Methotrexate dosage: 10 MG/WEEK INTRAMUSCULAR. During the same period patient was treated with PREDNISOLONE, FOLATES. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5080332-7
Methotrexate side effect was reported by a Health Professional from INDIA on Aug 07, 2006. Female patient, 17 years of age, was diagnosed with stem cell transplant and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: acute graft versus host disease in intestine, acute graft versus host disease in skin, alanine aminotransferase increased, aspartate aminotransferase increased, bladder disorder, blood bilirubin increased, blood creatinine increased, blood culture positive, blood lactate dehydrogenase increased. Methotrexate dosage: unknown. During the same period patient was treated with METHYLPREDNISOLONE, CYCLOSPORINE. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #5081214-7
Methotrexate side effect was reported by a Health Professional from INDIA on Aug 07, 2006. Female patient, 17 years of age, was diagnosed with stem cell transplant and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood bilirubin increased, blood creatinine increased, blood lactate dehydrogenase increased, blood urea increased, chills, escherichia infection. Methotrexate dosage: unknown. During the same period patient was treated with METHYLPREDNISOLONE, CYCLOSPORINE. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #4628337-1
Methotrexate side effect was reported by a Consumer or non-health professional from on Mar 29, 2005. Female patient, 83 years of age, weighting 119.0 lb, was diagnosed with rheumatoid arthritis

and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: acute myocardial infarction, alanine aminotransferase increased, anaemia, aspartate aminotransferase increased, blood alkaline phosphatase increased, cardiac failure congestive, hepatic congestion, mouth haemorrhage, multi-organ failure. Methotrexate dosage: 10 MG ORAL. During the same period patient was treated with LEXAPRO, COUMADIN, FUROSEMIDE, TIMENTIN, METOPROLOL TARTRATE, METOCLOPRAMIDE, LISINOPRIL, LEVOFLOXACIN. Patient was hospitalized. Patient died on 11/19/2004.

Methotrexate Side Effects Report #4596653-8
Methotrexate side effect was reported by a Consumer or non-health professional from on May 26, 2004. Male patient, 67 years of age, was diagnosed with rheumatoid arthritis

and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: adrenal insufficiency, aspartate aminotransferase increased, blood albumin decreased, blood alkaline phosphatase increased, blood lactate dehydrogenase increased, blood pressure decreased, cardiac arrest

, chlamydial infection. Methotrexate dosage: 5 MG WEEKLY/4 MG WEEKLY/2 MG WEEKLY/4 MG WEEKLY/6 MG WEEKLY PO. During the same period patient was treated with ETODOLAC, METHYLPREDNISOLONE, INFLIXIMAB, CALCITRIOL. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #5735544-3
Methotrexate side effect was reported by a Consumer or non-health professional from on May 06, 2008. Female patient, 66 years of age, was diagnosed with rheumatoid arthritis

, systemic antiviral treatment and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood bilirubin increased, encephalopathy, hepatic failure, hepatitis

, hepatitis b surface antigen positive, hypoalbuminaemia, prothrombin time prolonged. Methotrexate dosage: unknown. During the same period patient was treated with PREDNISOLONE, LAMIVUDINE. Patient was hospitalized. Patient died on 11/14/2006.

Methotrexate Side Effects Report #6022437-X
Methotrexate side effect was reported by a Consumer or non-health professional from TURKEY on Dec 15, 2008. Male patient, 64 years of age, was diagnosed with rheumatoid arthritis

and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, asthenia, blood albumin decreased, blood urea increased, c-reactive protein increased, decreased appetite, hypotension, jaundice

. Methotrexate dosage: 2.5 MG TWICE DAILY. During the same period patient was treated with MOXIFLOXACIN, METHYLPREDNISOLONE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #6056013-X
Methotrexate side effect was reported by a Consumer or non-health professional from TURKEY on Jan 15, 2009. Male patient, 64 years of age, was diagnosed with rheumatoid arthritis

and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, asthenia, blood lactate dehydrogenase increased, decreased appetite, epistaxis, hypotension, incorrect dose administered, jaundice

. Methotrexate dosage: 2.5 MG TWICE DAILY ORAL. During the same period patient was treated with MOXIFLOXACIN, METHYLPREDNISOLONE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4983210-4
Methotrexate side effect was reported by a Physician from TAIWAN, PROVINCE OF CHINA on Apr 06, 2006. Female patient, 55 years of age, was diagnosed with rheumatoid arthritis

and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood pressure systolic increased, carbuncle, dermatitis exfoliative, fatigue, febrile neutropenia. Methotrexate dosage: 7.5 MG PER WEEK. During the same period patient was treated with CELECOXIB, PREDNISOLONE, SULFASALAZINE, FOLIC ACID. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5700992-4
Methotrexate side effect was reported by a Consumer or non-health professional from JAPAN on Mar 25, 2008. Female patient, 54 years of age, was diagnosed with rheumatoid arthritis

and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, angiocentric lymphoma, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood lactate dehydrogenase increased, chest pain

, condition aggravated, diffuse large b-cell lymphoma, gamma-glutamyltransferase increased. Methotrexate dosage: 7.5 MG/WEEK ORAL. During the same period patient was treated with BUCILLAMINE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4596526-0
Methotrexate side effect was reported by a Health Professional from on Jan 28, 2005. Male patient, 53 years of age, was diagnosed with rheumatoid arthritis

, acute sinusitis and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: acute sinusitis, alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, gamma-glutamyltransferase increased. Methotrexate dosage: 15 MG WEEKLY, PO. During the same period patient was treated with ETANERCEPT, ANTIBIOTICS, DICLOFENAC, ALLOPURINOL, PANTOPRAZOLE, TAMSULOSIN HYDROCHLORIDE, ALENDRONATE. Patient recovered.

Methotrexate Side Effects Report #4982458-2
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Apr 04, 2006. Female patient, 48 years of age, was diagnosed with rheumatoid arthritis

and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal discomfort, alanine aminotransferase increased, aleukaemic leukaemia, anaemia, anorexia, aplastic anaemia, aspartate aminotransferase increased, asthenia, band neutrophil percentage increased. Methotrexate dosage: 10 MG PER WEEK (1 IN 1 WK), PO. During the same period patient was treated with PREDNISONE, PRIOXICAM, FOLIC ACID, CALCIUM, VITAMIN. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5205655-X
Methotrexate side effect was reported by a Pharmacist from UNITED STATES on Jan 05, 2007. Female patient, weighting 128.1 lb, was diagnosed with rheumatoid arthritis

and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, asthenia, decreased appetite, dyspnoea, pancytopenia, platelet count increased, white blood cell count decreased. Methotrexate dosage: 7.5 MG PO Q WEEK. During the same period patient was treated with NIFEDIPINE, CALCIUM, DIGOXIN, ALENDRONATE, ISOSORBIDE, FUROSEMIDE, OMEPRAZOLE, PREDNISONE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5054213-9
Methotrexate side effect was reported by a Consumer or non-health professional from on July 03, 2006. Male patient, 70 years of age, was diagnosed with psoriatic arthropathy and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal discomfort, activated partial thromboplastin time prolonged, ascites, aspartate aminotransferase increased, blood albumin decreased, blood creatinine increased, blood urea increased, bone marrow failure, c-reactive protein increased. Methotrexate dosage: 7.5 TO 15 MG PER WEEK. During the same period patient was treated with FOLATE, MELOXICAM, CARVEDILOL, MODURETICS, AMILORIDE HYDROCHLORIDE, HYDROCHLOROTHIAZIDE, RAMIPRIL, CLOPIDOGREL. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #5157973-1
Methotrexate side effect was reported by a Consumer or non-health professional from on Nov 15, 2006. Female patient, 40 years of age, was diagnosed with psoriatic arthropathy and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood lactate dehydrogenase increased, condition aggravated, gamma-glutamyltransferase increased, hepatitis toxic, intentional overdose, psoriatic arthropathy, stomatitis. Methotrexate dosage: 10 MG ONCE/WEEK. Patient recovered.

Methotrexate Side Effects Report #5408961-9
Methotrexate side effect was reported by a Physician from UNITED STATES on July 20, 2007. Female patient, 28 years of age, was diagnosed with psoriasis and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: aspartate aminotransferase increased, blood alkaline phosphatase increased, blood amylase increased, body temperature increased, cardio-respiratory arrest, cholelithiasis, fungal infection

, granuloma, haemoglobin decreased. Methotrexate dosage: 10 MG, WEEKLY. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5528332-4
Methotrexate side effect was reported by a Consumer or non-health professional from JAPAN on Nov 05, 2007. Male patient, 56 years of age, was diagnosed with prophylaxis against graft versus host disease, acute graft versus host disease and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, atrioventricular block complete, blood creatine phosphokinase increased, blood lactate dehydrogenase increased, cardiogenic shock, continuous haemodiafiltration, disease recurrence, graft versus host disease. Methotrexate dosage: 10 MG/M2, 7 MG/M2. During the same period patient was treated with CYCLOPHOSPHAMIDE, FLUDARABINE PHOSPHATE, TACROLIMUS, PREDNISOLONE. Patient died.

Methotrexate Side Effects Report #5246235-X
Methotrexate side effect was reported by a Physician from JAPAN on Feb 09, 2007. Male patient, 56 years of age, was diagnosed with prophylaxis, graft versus host disease and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: adenovirus infection, alanine aminotransferase increased, aspartate aminotransferase increased, atrioventricular block complete, blood creatine phosphokinase increased, blood lactate dehydrogenase increased, cardiogenic shock, continuous haemodiafiltration, disease recurrence. Methotrexate dosage: unknown. During the same period patient was treated with PREDNISOLONE, CYCLOPHOSPHAMIDE, FLUDARABINE PHOSPHATE, TACROLIMUS. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #4770982-7
Methotrexate side effect was reported by a Physician from JAPAN on Aug 11, 2005. Female patient, 17 years of age, weighting 108.0 lb, was diagnosed with osteosarcoma recurrent and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased. Methotrexate dosage: unknown. During the same period patient was treated with ONCOVIN, NASEA. Patient recovered.

Methotrexate Side Effects Report #5082196-4
Methotrexate side effect was reported by a Pharmacist from UNITED STATES on Aug 15, 2006. Male patient, 57 years of age, weighting 149.0 lb, was diagnosed with leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased. Methotrexate dosage: 360 MG/7.2 ML ONCE OVER 2H IV. During the same period patient was treated with BICARBONATE, CHLORHEXIDINE, ALUMINUM AND MAGNESIUM HYDROXIDE, ALUMINUM HYDROXIDE, NYSTATIN, ACETAMINOPHEN, DIPHENHYDRAMINE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5003547-2
Methotrexate side effect was reported by a Physician from SPAIN on Apr 28, 2006. Male patient, 16 years of age, was diagnosed with leukaemia, acute lymphocytic leukaemia, acute leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood lactate dehydrogenase increased, constipation

, gamma-glutamyltransferase increased, haematocrit decreased, haemoglobin decreased, hemiparesis. Methotrexate dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, MERCAPTOPURINE, PREDNISONE, DEXAMETHASONE, DAUNORUBICIN, VINCRISTINE, CYTARABINE. Patient was hospitalized and became disabled. Patient died on 01/01/2000.

Methotrexate Side Effects Report #4596760-X
Methotrexate side effect was reported by a Consumer or non-health professional from on May 04, 2004. Female patient, child 6 years of age, was diagnosed with juvenile arthritis, migraine

, overdose. Methotrexate dosage: unknown. During the same period patient was treated with PREDNISOLONE, HYDROXYCHLOROQUINE SULPHATE. Patient recovered.

Methotrexate Side Effects Report #5799059-9
Methotrexate side effect was reported by a Consumer or non-health professional from on June 27, 2008. Female patient, 67 years of age, was diagnosed with dermatomyositis, thrombocytopenia, leukopenia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, anaemia, anorexia, aspartate aminotransferase increased, leukopenia, mouth ulceration, nausea

, skin toxicity, thrombocytopenia. Methotrexate dosage: unknown. During the same period patient was treated with PREDNISOLONE, HYDROXYCHLOROQUINE SULPHATE, NEUPOGEN. Patient recovered.

Methotrexate Side Effects Report #4598984-4
Methotrexate side effect was reported by a Consumer or non-health professional from on Feb 06, 2004. Female patient, child 9 years of age, was diagnosed with bone sarcoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood albumin decreased, blood alkaline phosphatase increased, blood bilirubin increased, blood lactate dehydrogenase increased, bone marrow depression. Methotrexate dosage: unknown. During the same period patient was treated with BICARBONATE, GRANISETRON, CHLORPROMAZINE HYDROCHLORIDE, LEUCOVORIN, GLYCYRRHIZINATE POTASSIUM. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4877924-4
Methotrexate side effect was reported by a Health Professional from GERMANY on Dec 27, 2005. Female patient, child 4 years of age, weighting 41.89 lb, was diagnosed with bone sarcoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain

, aspartate aminotransferase increased, chills, disturbance in attention, electroencephalogram abnormal, encephalopathy, headache

, nausea

. Methotrexate dosage: unknown. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4816641-3
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Oct 20, 2005. Female patient, 36 years of age, was diagnosed with bone sarcoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, anxiety

, aspartate aminotransferase increased, blood bilirubin increased, cardiotoxicity, chest pain

, infusion related reaction, nodal rhythm. Methotrexate dosage: unknown. During the same period patient was treated with CISPLATIN, DOXORUBICIN, LEUCOVORIN CALCIUM, ONDANSETRON, LORAZEPAM, DEXAMETHASONE, ENOXAPRIN, PANTOPRAZOLE. Patient died.

Methotrexate Side Effects Report #5055288-3
Methotrexate side effect was reported by a Physician from JAPAN on July 04, 2006. Female patient, 33 years of age, weighting 108.0 lb, was diagnosed with bone sarcoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, back pain

. Methotrexate dosage: unknown. During the same period patient was treated with MEYLON, DIAMOX, NEOPHAGEN. Patient recovered.

Methotrexate Side Effects Report #5060087-2
Methotrexate side effect was reported by a Physician from JAPAN on July 11, 2006. Female patient, 33 years of age, was diagnosed with bone sarcoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, back pain

, erythema. Methotrexate dosage: unknown. During the same period patient was treated with NEOPHAGEN. Patient recovered.

Methotrexate Side Effects Report #4977606-4
Methotrexate side effect was reported by a Pharmacist from JAPAN on Mar 31, 2006. Female patient, 33 years of age, weighting 108.0 lb, was diagnosed with bone sarcoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, back pain

. Methotrexate dosage: unknown. Patient recovered.

Methotrexate Side Effects Report #4753706-9
Methotrexate side effect was reported by a Physician from JAPAN on Aug 11, 2005. Female patient, 18 years of age, was diagnosed with bone sarcoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, hepatic function abnormal. Methotrexate dosage: unknown. During the same period patient was treated with VINCRISTINE. Patient recovered.

Methotrexate Side Effects Report #4699651-9
Methotrexate side effect was reported by a Consumer or non-health professional from on Jan 27, 2005. Female patient, 17 years of age, was diagnosed with bone sarcoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood bilirubin increased, bulbar palsy, depressed level of consciousness, gamma-glutamyltransferase increased, haematocrit decreased, haemoglobin decreased, leukoencephalopathy. Methotrexate dosage: unknown. During the same period patient was treated with DOXORUBICIN HYDROCHLORIDE, CISPLATIN, CALCIUM FOLINATE. Patient recovered.

Methotrexate Side Effects Report #5936743-8
Methotrexate side effect was reported by a Physician from UNITED STATES on Oct 16, 2008. Male patient, child 10 years of age, weighting 82.67 lb, was diagnosed with bone sarcoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain

, alanine aminotransferase increased, aspartate aminotransferase increased, blister, blood bilirubin increased, blood creatinine increased, liver disorder, mucosal inflammation, renal disorder. Methotrexate dosage: unknown. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #6072969-3
Methotrexate side effect was reported by a Health Professional from UNITED STATES on Jan 26, 2009. Male patient, child 10 years of age, was diagnosed with bone sarcoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood potassium decreased, bone sarcoma, fluid retention, haemodialysis, haemoperfusion, neoplasm recurrence. Methotrexate dosage: 12000 MG/M**2. During the same period patient was treated with CISPLATIN, DOXORUBICIN, IFOSFAMIDE, ETOPOSIDE. Patient recovered.

Methotrexate Side Effects Report #6074743-0
Methotrexate side effect was reported by a Health Professional from UNITED STATES on Jan 26, 2009. Male patient, child 10 years of age, was diagnosed with bone sarcoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood potassium decreased, disease recurrence, fluid retention, haemoperfusion, hyperkalaemia, pleural effusion. Methotrexate dosage: 12000 MG/M**2. During the same period patient was treated with CISPLATIN, DOXORUBICIN, IFOSFAMIDE, ETOPOSIDE. Patient recovered.

Methotrexate Side Effects Report #4705204-6
Methotrexate side effect was reported by a Consumer or non-health professional from on June 13, 2005. Male patient, child 10 years of age, was diagnosed with bone sarcoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: aspartate aminotransferase increased, enzyme abnormality, hyporeflexia, nystagmus, somnolence, urinary incontinence

. Methotrexate dosage: unknown. Patient recovered.

Methotrexate Side Effects Report #4777926-2
Methotrexate side effect was reported by a Physician from JAPAN on Sept 05, 2005. Female patient was diagnosed with bone sarcoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood creatinine increased, haemodialysis. Methotrexate dosage: unknown. Patient recovered.

Methotrexate Side Effects Report #5005070-8
Methotrexate side effect was reported by a Health Professional from UNITED STATES on May 16, 2006. Female patient, weighting 114.0 lb, was diagnosed with bone sarcoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood bilirubin increased, blood creatinine increased, blood urea increased, hepatotoxicity, hypotension, infusion related reaction. Methotrexate dosage: unknown. During the same period patient was treated with BICARBONATE, DEXTROSE, ONDANSETRON. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4591479-3
Methotrexate side effect was reported by a Health Professional from on Feb 18, 2005. Male patient, 44 years of age, was diagnosed with bone marrow transplant

. Methotrexate dosage: 15 MG/M2. During the same period patient was treated with CYCLOPHOSPHAMIDE, BUSULFAN, IRRADIATION, CYCLOSPORINE. Patient died.

Methotrexate Side Effects Report #4592881-6
Methotrexate side effect was reported by a Health Professional from on Feb 16, 2005. Male patient, 40 years of age, was diagnosed with bone marrow transplant

, hepatitis b surface antigen positive, hepatitis chronic active. Methotrexate dosage: unknown. During the same period patient was treated with STEROIDS NOS, AZATHIOPRINE, BUSULPHAN, CYCLOPHOSPHAMIDE, CYCLOSPORINE. Patient recovered.

Methotrexate Side Effects Report #4594793-0
Methotrexate side effect was reported by a Consumer or non-health professional from on Feb 07, 2005. Male patient, 70 years of age, was diagnosed with bladder cancer stage iii and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood potassium increased, blood pressure decreased, bone marrow depression, cardiac arrest

, dialysis

, ileus paralytic, mouth breathing. Methotrexate dosage: 20 MG. During the same period patient was treated with CISPLATIN, VINBLASTINE SULPHATE, DOXORUBICIN, LEUCOVORIN CALCIUM, ALLOPURINOL, VALSARTAN, DOXAZOSIN MESYLATE, DILTIAZEM HYDROCHLORIDE. Patient died.

Methotrexate Side Effects Report #4600041-5
Methotrexate side effect was reported by a Consumer or non-health professional from on Feb 07, 2005. Male patient, 70 years of age, was diagnosed with bladder cancer stage iii and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood creatinine increased, blood potassium increased, blood pressure decreased, bone marrow depression, cardiac arrest

, haemodialysis, ileus paralytic. Methotrexate dosage: 20 MG. During the same period patient was treated with CISPLATIN, VINBLASTINE SULPHATE, DOXORUBICIN HYDROCHLORIDE, LEUCOVORIN CALCIUM, ALLOPURINOL, VALSARTAN, DOXAZOSIN MESYLATE, DILTIAZEM HYDROCHLORIDE. Patient died.

Methotrexate Side Effects Report #4613289-0
Methotrexate side effect was reported by a Health Professional from on Oct 01, 2004. Female patient, child 12 years of age, was diagnosed with arthritis

, dermatomyositis and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: aspartate aminotransferase increased, jaundice

, liver transplant

. Methotrexate dosage: 10 MG WEEKLY PO. During the same period patient was treated with PREDNISOLONE, METHYLPREDNISOLONE, CALCIUM CARNOBATE, PENICILLIN V POTASSIUM, FLUCONAZOLE, IBUPROFEN. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4869708-8
Methotrexate side effect was reported by a Health Professional from JAPAN on Dec 07, 2005. Male patient, 63 years of age, weighting 119.0 lb, was diagnosed with acute myeloid leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: acidosis, activated partial thromboplastin time prolonged, acute myeloid leukaemia, alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood bilirubin increased, blood lactate dehydrogenase increased, condition aggravated. Methotrexate dosage: unknown. During the same period patient was treated with MYLOTARG. Patient died on 11/09/2005.

Methotrexate Side Effects Report #4911113-X
Methotrexate side effect was reported by a Consumer or non-health professional from on Jan 31, 2006. Male patient, child 9 years of age, was diagnosed with acute lymphocytic leukaemia, convulsion and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, coma, convulsion, hepatotoxicity, neurotoxicity. Methotrexate dosage: unknown. During the same period patient was treated with DIAZEPAM. Patient recovered.

Methotrexate Side Effects Report #5500074-0
Methotrexate side effect was reported by a Consumer or non-health professional from GERMANY on Oct 09, 2007. Female patient, 14 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood brain barrier defect, blood immunoglobulin a decreased, bone marrow failure, guillain-barre syndrome

, leukaemia recurrent, neurogenic bladder, neurotoxicity. Methotrexate dosage: unknown. During the same period patient was treated with CYTARABINE, PREDNISOLONE. Patient was hospitalized and became disabled. Patient died.

Methotrexate Side Effects Report #5792339-2
Methotrexate side effect was reported by a Physician from CANADA on June 12, 2008. Male patient, child 11 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abscess fungal, abscess intestinal, alanine aminotransferase increased, aspartate aminotransferase increased, atelectasis, biopsy liver abnormal, blood culture positive, catheter site infection, diffuse alveolar damage. Methotrexate dosage: unknown. During the same period patient was treated with VINCRISTINE, DOXORUBICIN, ASPARAGINASE, PREDNISONE, TICARCILLIN, TOBRAMYCIN, VANCOMYCIN. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #5920444-6
Methotrexate side effect was reported by a Physician from CANADA on Sept 30, 2008. Male patient, child 11 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abscess fungal, alanine aminotransferase increased, aspartate aminotransferase increased, atelectasis, condition aggravated, diffuse alveolar damage, fungal infection

, gastrointestinal disorder. Methotrexate dosage: unknown. During the same period patient was treated with ADRIAMYCIN PFS. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #5388631-6
Methotrexate side effect was reported by a Consumer or non-health professional from on July 11, 2007. Male patient, 83 years of age, weighting 224.9 lb, was diagnosed with fluid retention and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood creatine phosphokinase increased, myoglobin blood increased, paraparesis, rhabdomyolysis, weight decreased. Methotrexate dosage: 20-40 MG AS NEEDED. During the same period patient was treated with FUROSEMIDE, ERYTHROMYCIN, METOPROLOL SUCCINATE, AMLODIPINE, VALSARTAN AND HYDROCHLOROTHIAZIDE, ASPIRIN, SIMVASTATIN. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4592781-1
Methotrexate side effect was reported by a Physician from on Feb 07, 2005. Female patient, child 6 years of age, was diagnosed with juvenile arthritis and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: aspartate aminotransferase increased. Methotrexate dosage: 15 MG WEEKLY SC. During the same period patient was treated with NAPROXEN, ONDANSETRON, ETANERCEPT. Patient recovered.

Methotrexate Side Effects Report #4596773-8
Methotrexate side effect was reported by a Consumer or non-health professional from on July 19, 2004. Female patient, 47 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, alveolitis allergic, aspartate aminotransferase increased, blood ph increased, blood pressure decreased, enteritis, heart rate increased, hypersensitivity, hypoxia. Methotrexate dosage: 25 MG BID. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4746668-1
Methotrexate side effect was reported by a Health Professional from UNITED STATES on July 29, 2005. Female patient, 47 years of age, was diagnosed with rheumatoid arthritis

and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: acquired diaphragmatic eventration, alanine aminotransferase increased, aspartate aminotransferase increased, atelectasis, blood albumin decreased, blood calcium decreased, blood glucose increased, flatulence, high density lipoprotein decreased. Methotrexate dosage: 10 MG WEEKLY PO. During the same period patient was treated with ENBREL, ZOCOR. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4579150-5
Methotrexate side effect was reported by a Consumer or non-health professional from on Sept 03, 2004. Female patient, 39 years of age, was diagnosed with rheumatoid arthritis

and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased. Methotrexate dosage: 20 MG 1X PER 1WK, ORAL. During the same period patient was treated with ENBREL, PREDNISONE, BENAZEPRIL, ESTRADIOL. Patient recovered.

Methotrexate Side Effects Report #4952891-3
Methotrexate side effect was reported by a Consumer or non-health professional from FRANCE on Feb 23, 2006. Male patient, 28 years of age, weighting 123.5 lb, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: agitation, alanine aminotransferase increased, antithrombin iii decreased, anuria, ascites, aspartate aminotransferase increased, asterixis, blood alkaline phosphatase increased, blood bilirubin increased. Methotrexate dosage: unknown. During the same period patient was treated with PURINETHOL, GLEEVEC, ROCEPHIN, OFLOCET, MOPRAL, VFEND, SPECIAFOLDINE. Patient was hospitalized. Patient died on 02/18/2006.

Methotrexate Side Effects Report #5228751-X
Methotrexate side effect was reported by a Consumer or non-health professional from GERMANY on Jan 19, 2007. Female patient, 14 years of age, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, arthralgia, aspartate aminotransferase increased, asthenia, atonic urinary bladder, blood immunoglobulin a decreased, blood immunoglobulin m decreased, bone marrow failure, gait disturbance. Methotrexate dosage: 12 MG PER_CYCLE IT. During the same period patient was treated with CYTARABINE, PREDNISOLONE, IBUPROFEN. Patient recovered.

Methotrexate Side Effects Report #5243048-X
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Feb 20, 2007. Female patient, weighting 105.4 lb, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased. Methotrexate dosage: 11345 MG. During the same period patient was treated with CYCLOPHOSPHAMIDE, CYTARABINE, DOXORUBICIN HYDROCHLORIDE, HYDROCORTISONE, LEUCOVORIN CALCIUM, PREDNISONE, RITUXIMAB. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5170791-3
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Dec 06, 2006. Female patient, weighting 155.4 lb, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, leukopenia, neutropenia. Methotrexate dosage: unknown. During the same period patient was treated with RITUXIMAB, LEUCOVORIN CALCIUM. Patient recovered.

Methotrexate and aspartate aminotransferase increased

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Methotrexate and aspartate aminotransferase increased Patient Reports February 11, 2012

side effects of Methotrexate