Methotrexate and abdominal pain Patient Reports February 11, 2012

Methotrexate Side Effects Report #5481798-0
Methotrexate side effect was reported by a Consumer or non-health professional from on Oct 02, 2007. Male patient, child 9 years of age, was diagnosed with t-cell type acute leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , confusional state, constipation , convulsion, dizziness , headache , hypertension, mental status changes. Methotrexate dosage: unknown. During the same period patient was treated with PREDNISONE, CYTARABINE, VINCRISTINE, DEZROXOZANE, DOXORUBICIN. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4642128-7
Methotrexate side effect was reported by a Consumer or non-health professional from on Apr 15, 2005. Male patient, child 6 years of age, was diagnosed with stem cell transplant and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , cachexia, cystitis haemorrhagic, diffuse large b-cell lymphoma, epstein-barr virus infection, graft versus host disease, hepatomegaly, intestinal perforation, leukodystrophy. Methotrexate dosage: unknown. During the same period patient was treated with ANTITHYMOCYTE IMMUNOGLOBULIN, CYCLOSPORINE. Patient died.

Methotrexate Side Effects Report #4745284-5
Methotrexate side effect was reported by a Health Professional from TURKEY on Aug 08, 2005. Female patient, 41 years of age, was diagnosed with stem cell transplant and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , blood bilirubin increased, graft versus host disease, venoocclusive liver disease. Methotrexate dosage: unknown. During the same period patient was treated with CYCLOSPORINE. Patient died.

Methotrexate Side Effects Report #4745274-2
Methotrexate side effect was reported by a Health Professional from TURKEY on Aug 08, 2005. Male patient, 39 years of age, was diagnosed with stem cell transplant and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , blood bilirubin increased, graft versus host disease, infection , multi-organ failure, venoocclusive liver disease. Methotrexate dosage: unknown. During the same period patient was treated with CYCLOSPORINE. Patient died.


Methotrexate Side Effects Report #4745255-9
Methotrexate side effect was reported by a Health Professional from TURKEY on Aug 08, 2005. Male patient, 38 years of age, was diagnosed with stem cell transplant and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , blood bilirubin increased, fungal infection , venoocclusive liver disease. Methotrexate dosage: unknown. During the same period patient was treated with CYCLOSPORINE. Patient died.

Methotrexate Side Effects Report #4745268-7
Methotrexate side effect was reported by a Health Professional from TURKEY on Aug 08, 2005. Female patient, 29 years of age, was diagnosed with stem cell transplant and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , blood bilirubin increased, multi-organ failure, pneumonia , venoocclusive liver disease. Methotrexate dosage: unknown. During the same period patient was treated with CYCLOSPORINE. Patient died.

Methotrexate Side Effects Report #4745276-6
Methotrexate side effect was reported by a Health Professional from TURKEY on Aug 08, 2005. Female patient, 29 years of age, was diagnosed with stem cell transplant and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , blood bilirubin increased, graft versus host disease, multi-organ failure, venoocclusive liver disease. Methotrexate dosage: unknown. During the same period patient was treated with CYCLOSPORINE. Patient died.

Methotrexate Side Effects Report #4745273-0
Methotrexate side effect was reported by a Health Professional from TURKEY on Aug 08, 2005. Female patient, 25 years of age, was diagnosed with stem cell transplant and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , blood bilirubin increased, haemorrhage, pneumonia , venoocclusive liver disease. Methotrexate dosage: unknown. During the same period patient was treated with CYCLOSPORINE. Patient died.

Methotrexate Side Effects Report #4745283-3
Methotrexate side effect was reported by a Health Professional from TURKEY on Aug 08, 2005. Male patient, 16 years of age, was diagnosed with stem cell transplant and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , blood bilirubin increased, infection , multi-organ failure, venoocclusive liver disease. Methotrexate dosage: unknown. During the same period patient was treated with CYCLOSPORINE. Patient died.


Methotrexate Side Effects Report #5203590-4
Methotrexate side effect was reported by a Health Professional from UNITED KINGDOM on Dec 20, 2006. Female patient, 73 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , aortic arteriosclerosis, aortic calcification, arteriosclerosis coronary artery, blood pressure diastolic decreased, bone marrow disorder, coronary artery occlusion, coronary artery thrombosis, dehydration. Methotrexate dosage: 7.5 MG, PO, QD;. During the same period patient was treated with PREDNISOLONE, FOLIC ACID, MORPHINE SULPHATE, ROFECOXIB, NITRAZEPAM. Patient was hospitalized. Patient died on 07/04/2004.

Methotrexate Side Effects Report #5490548-3
Methotrexate side effect was reported by a Health Professional from CANADA on Oct 15, 2007. Male patient, 62 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , meningitis aseptic, no therapeutic response, tenosynovitis. Methotrexate dosage: INITAILY PT RECEIVED ORAL METHOTREXATE,LATER CHANGED TO IM 17.5 TO 20MG/WEEK DUE LACK OFRESPONSE.. During the same period patient was treated with ETANERCEPT, PREDNISONE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5380277-9
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on June 25, 2007. Male patient, child 6 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , abscess , anaemia, arthralgia, c-reactive protein increased, condition aggravated, dizziness , dyspepsia, erythema. Methotrexate dosage: 7.5 MG WEEKLY SC. During the same period patient was treated with PREDNISOLONE, IMMUNOGLOBULINS, FOLIC ACID. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4736433-3
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on July 19, 2005. Male patient, child 6 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , anaemia, condition aggravated, dizziness , dyspepsia, juvenile arthritis, nausea , pyrexia, stomach discomfort. Methotrexate dosage: 7.5 MG WEEKLY / 12.5 MG WEEKLY. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4738112-5
Methotrexate side effect was reported by a Physician from UNITED KINGDOM on July 19, 2005. Male patient, child 6 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , abscess , anaemia, arthralgia, condition aggravated, disease recurrence, dizziness , dyspepsia, feeling hot. Methotrexate dosage: 22 MG WEEKLY SC. During the same period patient was treated with PREDNISOLONE, IMMUNOGLOBULINS, FOLIC ACID. Patient was hospitalized. Patient recovered.


Methotrexate Side Effects Report #4761063-7
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on July 19, 2005. Male patient, child 6 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , anaemia, arthralgia, c-reactive protein increased, condition aggravated, dizziness , dyspepsia, injection site erythema, injection site haemorrhage. Methotrexate dosage: 7.5 MG WEEKLY SC. During the same period patient was treated with PREDNISOLONE, IMMUNOGLOBULINS, FOLIC ACID. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5683234-8
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Mar 20, 2008. Female patient, 55 years of age, weighting 155.0 lb, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , cholelithiasis, ear pain, headache , hepatitis cholestatic, lymphadenopathy, pyrexia, swelling face. Methotrexate dosage: unknown. During the same period patient was treated with HYDROXYCHLOROQUINE, MELOXICAN. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5929472-8
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 09, 2007. Female patient, 24 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain . Methotrexate dosage: 4 TABLETS (10 MG) WEEKLY (2.5 MG,1 IN 1 WK), PO. During the same period patient was treated with FOLIC ACID, SOMA, PERCOCET, PREDNISONE. Patient recovered.

Methotrexate Side Effects Report #4622911-4
Methotrexate side effect was reported by a Consumer or non-health professional from on Mar 11, 2005. Male patient, 38 years of age, was diagnosed with psoriasis and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , colitis, diarrhoea, rectal haemorrhage. Methotrexate dosage: 10 MG WEEKLY PO. During the same period patient was treated with ROFECOXIB, BETAMETHASONE, CALCIPOTRIOL. Patient recovered.

Methotrexate Side Effects Report #4558537-0
Methotrexate side effect was reported by a Consumer or non-health professional from on Jan 04, 2005. Female patient was diagnosed with pregnancy  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , off label use, ruptured ectopic pregnancy. Methotrexate dosage: unknown. Patient recovered.


Methotrexate Side Effects Report #5156656-1
Methotrexate side effect was reported by a Health Professional from UNITED STATES on Oct 31, 2006. Female patient, 15 years of age, was diagnosed with juvenile arthritis and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , alcohol use, dizziness , gastritis, haematocrit decreased, haemoglobin decreased, occult blood positive, tachycardia. Methotrexate dosage: 25 MG; QW; PO. During the same period patient was treated with PREDNISONE, NAPROSYN, FOLIC ACID, LANSOPRAZOLE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4998623-4
Methotrexate side effect was reported by a Consumer or non-health professional from SWITZERLAND on Apr 28, 2006. Female patient, child 12 years of age, was diagnosed with juvenile arthritis and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , balance disorder, colour vision tests abnormal, diarrhoea, diplopia, vision blurred, visual disturbance, vomiting. Methotrexate dosage: 10 MG WEEKLY SC. Patient recovered.

Methotrexate Side Effects Report #5853429-9
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Dec 28, 2007. Male patient, weighting 142.2 lb, was diagnosed with juvenile arthritis and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , anorexia, fatigue, malaise, weight decreased. Methotrexate dosage: 15 MG WEEKLY SC. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4990911-0
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Apr 13, 2006. Male patient, 14 years of age, was diagnosed with hodgkin's disease , histoplasmosis and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , back pain , bone marrow toxicity, c-reactive protein increased, chills, cough, eating disorder , febrile neutropenia. Methotrexate dosage: unknown. During the same period patient was treated with PREDNISONE, VINBLASTINE SULPHATE, DOXORUBICIN, ITRACONAZOLE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #6023402-9
Methotrexate side effect was reported by a Consumer or non-health professional from FRANCE on Dec 26, 2008. Female patient, 53 years of age, was diagnosed with dermatomyositis, metastasis and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , asthenia, pneumatosis intestinalis, pneumoperitoneum. Methotrexate dosage: unknown. During the same period patient was treated with FLUOROURACIL, VINORELBINE, PREDNISONE, METHYLPREDNISOLONE SUCCINATE. Patient was hospitalized. Patient recovered.


Methotrexate Side Effects Report #6031892-0
Methotrexate side effect was reported by a Consumer or non-health professional from FRANCE on Jan 07, 2009. Female patient, 53 years of age, was diagnosed with dermatomyositis, metastasis and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , asthenia, pneumatosis intestinalis, pneumoperitoneum. Methotrexate dosage: unknown. During the same period patient was treated with FLUOROURACIL, VINORELBINE, PREDNISONE, METHYLPREDNISOLONE SUCCINATE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4726250-2
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on July 25, 2005. Female patient, weighting 223.0 lb, was diagnosed with central nervous system lymphoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , chills, pyrexia, urosepsis. Methotrexate dosage: unknown. During the same period patient was treated with THIOTEPA. Patient recovered.

Methotrexate Side Effects Report #4731631-7
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 02, 2005. Female patient, weighting 223.0 lb, was diagnosed with central nervous system lymphoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , chills, febrile neutropenia, thrombocytopenia. Methotrexate dosage: unknown. During the same period patient was treated with THIOTEPA. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4877924-4
Methotrexate side effect was reported by a Health Professional from GERMANY on Dec 27, 2005. Female patient, child 4 years of age, weighting 41.89 lb, was diagnosed with bone sarcoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , aspartate aminotransferase increased, chills, disturbance in attention, electroencephalogram abnormal, encephalopathy, headache , nausea . Methotrexate dosage: unknown. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5936743-8
Methotrexate side effect was reported by a Physician from UNITED STATES on Oct 16, 2008. Male patient, child 10 years of age, weighting 82.67 lb, was diagnosed with bone sarcoma and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , alanine aminotransferase increased, aspartate aminotransferase increased, blister, blood bilirubin increased, blood creatinine increased, liver disorder, mucosal inflammation, renal disorder. Methotrexate dosage: unknown. Patient was hospitalized. Patient recovered.


Methotrexate Side Effects Report #4567381-X
Methotrexate side effect was reported by a Consumer or non-health professional from on Jan 12, 2005. Female patient, 14 years of age, was diagnosed with arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , nausea . Methotrexate dosage: 25 MG WEEKLY SC. During the same period patient was treated with ETANERCEPT, IBUPROFEN, PREDNISOLONE, FOLIC ACID. Patient recovered.

Methotrexate Side Effects Report #4650095-5
Methotrexate side effect was reported by a Consumer or non-health professional from on Jan 12, 2005. Female patient, 14 years of age, was diagnosed with arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , nausea . Methotrexate dosage: 25 MG WEEKLY SC. During the same period patient was treated with ETANERCEPT, IBUPROFEN, PREDNISOLONE, FOLIC ACID. Patient recovered.

Methotrexate Side Effects Report #5848056-3
Methotrexate side effect was reported by a Consumer or non-health professional from FRANCE on Aug 01, 2008. Female patient, 52 years of age, was diagnosed with ankylosing spondylitis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , arthralgia, asthenia, bedridden, chest pain , chills, cough, cytomegalovirus infection , interstitial lung disease. Methotrexate dosage: 15 MG WEEKLY, ORAL; DECREASED TO 10 MG WEEKLY. During the same period patient was treated with PREDNISONE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5243088-0
Methotrexate side effect was reported by a Consumer or non-health professional from on Feb 14, 2007. Female patient, child 8 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , abdominal rigidity, abdominal tenderness, bowel sounds abnormal, intussusception, vomiting. Methotrexate dosage: unknown. Patient recovered.

Methotrexate Side Effects Report #6127429-8
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Mar 11, 2009. Male patient, child 3 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , back pain , breath odour, cardiac failure, hepatic enzyme increased, hepatic failure, herpes zoster, liver tenderness, lymphopenia. Methotrexate dosage: unknown. During the same period patient was treated with VINCRISTINE, DEXAMETHASONE, MERCAPTOPURINE. Patient was hospitalized. Patient recovered.


Methotrexate Side Effects Report #5582974-9
Methotrexate side effect was reported by a Physician from GERMANY on Dec 20, 2007. Male patient, 17 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , acute respiratory distress syndrome, anaemia, aspergillosis, blood culture positive, bone marrow failure, bronchial ulceration, disease progression, febrile neutropenia. Methotrexate dosage: unknown. During the same period patient was treated with VINCRISTINE, DAUNORUBICIN, ASPARAGINASE, DEXAMETHASONE, PREDNISONE. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #4828889-2
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Nov 14, 2005. Female patient, weighting 125.7 lb, was diagnosed with acute lymphocytic leukaemia and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , acute respiratory distress syndrome, anaemia, ascites, cardiac disorder, central line infection, coagulopathy, depressed level of consciousness. Methotrexate dosage: unknown. During the same period patient was treated with DEXAMETHASONE, CYCLOPHOSPHAMIDE, CYTARABINE, MERCAPTOPURINE, VINCRISTINE, PEG ASPARAGINASE, PEG ASPARAGINASE. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #5923151-9
Methotrexate side effect was reported by a Physician from UNITED STATES on Oct 08, 2008. Female patient, 62 years of age, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , chills, cough, pneumonia , pyrexia. Methotrexate dosage: 12.5 MG, 1/WEEK, ORAL. During the same period patient was treated with ENBREL, PREDNISONE, LEUCOVORIN CALCIUM. Patient recovered.

Methotrexate Side Effects Report #5985280-3
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Nov 19, 2008. Female patient, 47 years of age, weighting 121.3 lb, was diagnosed with rheumatoid arthritis  and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , anaphylactic shock, ovarian cancer metastatic, pelvic pain , pleural effusion, rash . Methotrexate dosage: unknown. During the same period patient was treated with KINERET, REMICADE, RITUXIMAB, AZATHIOPRINE, CYCLOPHOSPHAMIDE, CYCLOSPORINE, HYDROXYCHLORQUINE. Patient died on 04/02/2006.

Methotrexate Side Effects Report #4843516-6
Methotrexate side effect was reported by a Physician from UNITED KINGDOM on Nov 23, 2005. Female patient, 30 years of age, was diagnosed with stem cell transplant and was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , acute myeloid leukaemia recurrent, cerebellar syndrome, coordination abnormal, diarrhoea, eye movement disorder, nervousness, opsoclonus myoclonus, speech disorder. Methotrexate dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, CAMPATH, IRRADIATION, CYCLOSPORINE. Patient was hospitalized. Patient died.


Methotrexate Side Effects Report #5320284-5
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on May 03, 2007. Male patient, weighting 146.2 lb, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , blood creatinine increased, blood potassium increased, blood urea increased, pyrexia, renal tubular necrosis, vomiting. Methotrexate dosage: 458 MG. During the same period patient was treated with VINCRISTINE SULPHATE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5060699-6
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on July 20, 2006. Female patient, weighting 26.46 lb, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , activated partial thromboplastin time prolonged, agitation, atelectasis, brain herniation, brain oedema, cerebellar infarction, cerebral disorder, cerebral haemorrhage. Methotrexate dosage: unknown. Patient was hospitalized. Patient died.

Methotrexate Side Effects Report #5713973-1
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Apr 22, 2008. Female patient, weighting 181.4 lb, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , faecaloma, pulmonary embolism . Methotrexate dosage: unknown. During the same period patient was treated with RITUXIMAB, TEMOZOLOMIDE, LEUCOVORIN CALCIUM. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5951247-4
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Nov 12, 2008. Male patient, weighting 167.8 lb, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , colitis, dehydration, febrile neutropenia, haemoglobin decreased, headache , hydrocephalus , hypertension, meningitis staphylococcal. Methotrexate dosage: unknown. During the same period patient was treated with RITUXIMAB, TEMOZOLOMIDE, DILAUDID. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #4731664-0
Methotrexate side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 02, 2005. Female patient, weighting 223.0 lb, was treated with Methotrexate. After drug was administered, patient experienced the following side effects: abdominal pain , chills, febrile neutropenia, infection , thrombocytopenia. Methotrexate dosage: unknown. During the same period patient was treated with THIOTEPA. Patient recovered.