Metformin and lactic acidosis Patient Reports February 10, 2012



Metformin Side Effects Report #5779586-0
Metformin side effect was reported by a Health Professional from TAIWAN, PROVINCE OF CHINA on June 02, 2008. Female patient, 28 years of age, was diagnosed with weight control What is  weight control and was treated with Metformin. After drug was administered, patient experienced the following side effects: anion gap increased, intentional overdose, lactic acidosis, metabolic acidosis, suicide attempt. Metformin dosage: 500 MG, ORAL; 39.50 G, OVERDOSE (APPROX., 80 TABLETS). Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5794566-7
Metformin side effect was reported by a Health Professional from TAIWAN, PROVINCE OF CHINA on June 20, 2008. Female patient, 28 years of age, was diagnosed with weight control What is  weight control and was treated with Metformin. After drug was administered, patient experienced the following side effects: intentional overdose, lactic acidosis, suicide attempt. Metformin dosage: 500 MG, ORAL : 39.50 G, OVERDOSE (APPROX., 80 TABLETS). Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5935352-4
Metformin side effect was reported by a Health Professional from TAIWAN, PROVINCE OF CHINA on Oct 27, 2008. Female patient, 28 years of age, was diagnosed with weight control What is  weight control and was treated with Metformin. After drug was administered, patient experienced the following side effects: hypoglycaemia, intentional overdose, lactic acidosis, normal newborn, pregnancy What is  pregnancy, suicide attempt. Metformin dosage: 1 DF = APPROXIMATELY 80 TABLETS 500 MG (TOTAL DOSE OF 39.5G). During the same period patient was treated with BICARBONATE, CHARCOAL ACTIVATED. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5939894-7
Metformin side effect was reported by a Health Professional from TAIWAN, PROVINCE OF CHINA on Oct 31, 2008. Female patient, 28 years of age, was diagnosed with weight control What is  weight control and was treated with Metformin. After drug was administered, patient experienced the following side effects: hypoglycaemia, intentional overdose, lactic acidosis, metabolic acidosis, normal newborn, pregnancy What is  pregnancy, suicide attempt. Metformin dosage: 1 DF = APPROXIMATELY 80 TABLETS 500 MG (TOTAL DOSE OF 39.5G). During the same period patient was treated with BICARBONATE, CHARCOAL ACTIVATED. Patient was hospitalized. Patient recovered.


Metformin Side Effects Report #5957630-5
Metformin side effect was reported by a Health Professional from TAIWAN, PROVINCE OF CHINA on Nov 13, 2008. Female patient, 28 years of age, was diagnosed with weight control What is  weight control, acidosis, fluid replacement, hypoglycaemia and was treated with Metformin. After drug was administered, patient experienced the following side effects: agitation, disorientation, hypoglycaemia, intentional overdose, lactic acidosis, metabolic acidosis, normal newborn, pregnancy What is  pregnancy. Metformin dosage: APPROXIMATELY 80 TABLETS 500 MG (TOTAL DOSE OF 39.5G). During the same period patient was treated with BICARBONATE, CHARCOAL ACTIVATED, CHLORIDE, GLUCOSE. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #6046230-7
Metformin side effect was reported by a Health Professional from GERMANY on Jan 16, 2009. Female patient, 85 years of age, was diagnosed with type 2 diabetes mellitus, hypertension and was treated with Metformin. After drug was administered, patient experienced the following side effects: lactic acidosis, renal failure acute. Metformin dosage: unknown. During the same period patient was treated with ACTRAPHANE, AMLODIPINE BESYLATE, ENALAPRIL MALEATE, METOPROLOL. Patient recovered.

Metformin Side Effects Report #6047555-1
Metformin side effect was reported by a Health Professional from GERMANY on Jan 16, 2009. Female patient, 85 years of age, was diagnosed with type 2 diabetes mellitus, hypertension and was treated with Metformin. After drug was administered, patient experienced the following side effects: lactic acidosis, renal failure acute. Metformin dosage: 100 MG, UNK. During the same period patient was treated with ACTRAPHANE, AMLODIPINE, ENALAPRIL, METOPROLOL TARTRATE. Patient recovered.

Metformin Side Effects Report #6055022-4
Metformin side effect was reported by a Physician from GERMANY on Jan 19, 2009. Female patient, 85 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: lactic acidosis, renal failure acute. Metformin dosage: 100 MG, QD, ORAL. During the same period patient was treated with ISOPHANE INSULIN, AMLODIPINE, ENALAPRIL MALEATE, METOPROLOL TARTRATE. Patient recovered.

Metformin Side Effects Report #6060158-8
Metformin side effect was reported by a Consumer or non-health professional from GERMANY on Jan 16, 2009. Female patient, 85 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: lactic acidosis, renal failure acute. Metformin dosage: 100 MG ORAL. During the same period patient was treated with ACTRAPHANE, AMLODIPINE, ENALAPRIL MALEATE, METOPROLOL TARTRATE. Patient recovered.


Metformin Side Effects Report #5883406-3
Metformin side effect was reported by a Physician from GERMANY on Sept 02, 2008. Female patient, 84 years of age, weighting 176.4 lb, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: lactic acidosis, multi-organ failure. Metformin dosage: 850 MG; DAILY; ORAL. Patient died on 07/23/2008.

Metformin Side Effects Report #5884036-X
Metformin side effect was reported by a Consumer or non-health professional from GERMANY on Sept 02, 2008. Female patient, 84 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: lactic acidosis, multi-organ failure. Metformin dosage: 850 MG 1 DAY ORAL. Patient died.

Metformin Side Effects Report #5886918-1
Metformin side effect was reported by a Health Professional from GERMANY on Sept 02, 2008. Female patient, 84 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: lactic acidosis, multi-organ failure. Metformin dosage: 850 MG;DAILY. Patient died.

Metformin Side Effects Report #5888807-5
Metformin side effect was reported by a Consumer or non-health professional from GERMANY on Sept 02, 2008. Female patient, 84 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: lactic acidosis, multi-organ failure. Metformin dosage: 850 MG, ORAL, DAILY. Patient died.

Metformin Side Effects Report #5422288-0
Metformin side effect was reported by a Pharmacist from UNITED STATES on Aug 20, 2007. Male patient, 83 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: hypoglycaemia, lactic acidosis, renal failure. Metformin dosage: 500 MG PO. During the same period patient was treated with CASODEX, THEOPHYLLINE, LISINOPRIL, GLUCOPHAGE, GLYBURIDE, HYDROCHLOROTHIAZIDE, ASPIRIN. Patient was hospitalized. Patient recovered.


Metformin Side Effects Report #5482504-6
Metformin side effect was reported by a Health Professional from GERMANY on Oct 03, 2007. Male patient, 83 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: abdominal pain What is  abdominal pain, hypotension, lactic acidosis, renal failure acute, vomiting. Metformin dosage: unknown. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5931619-4
Metformin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Oct 30, 2006. Male patient, 83 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: abdominal pain What is  abdominal pain, haemodialysis, hypotension, lactic acidosis, renal failure acute, vomiting. Metformin dosage: 2000 MG; PO. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5932190-3
Metformin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on May 29, 2006. Male patient, 83 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: lactic acidosis, renal failure acute. Metformin dosage: unknown. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #6016281-7
Metformin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Dec 08, 2008. Male patient, 83 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: abdominal pain What is  abdominal pain, haemodialysis, hypotension, lactic acidosis, renal failure acute, vomiting. Metformin dosage: (850 MG BID OR 1 G BID). Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #6101052-3
Metformin side effect was reported by a Health Professional from GERMANY on Feb 24, 2009. Male patient, 83 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: abdominal pain What is  abdominal pain, hypotension, lactic acidosis, renal failure acute, vomiting. Metformin dosage: 850MG OR 1G. Patient was hospitalized. Patient recovered.


Metformin Side Effects Report #5484814-5
Metformin side effect was reported by a Physician from SPAIN on Sept 28, 2007. Male patient, 82 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: abdominal pain What is  abdominal pain, acute pulmonary oedema, anuria, dyspnoea, haemodialysis, lactic acidosis, myocardial infarction, renal failure acute. Metformin dosage: unknown. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5487449-3
Metformin side effect was reported by a Physician from SPAIN on Oct 10, 2007. Male patient, 82 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: acute pulmonary oedema, anuria, haemodialysis, lactic acidosis, myocardial infarction, post procedural complication, renal failure acute. Metformin dosage: unknown. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5527864-2
Metformin side effect was reported by a Health Professional from SPAIN on Nov 26, 2007. Male patient, 82 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: anuria, lactic acidosis, myocardial infarction, pulmonary oedema, renal failure acute. Metformin dosage: unknown. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5712683-4
Metformin side effect was reported by a Consumer or non-health professional from SPAIN on Apr 09, 2008. Male patient, 82 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: abdominal pain What is  abdominal pain, acute myocardial infarction, blood glucose abnormal, haemodialysis, lactic acidosis, pulmonary oedema, renal failure acute. Metformin dosage: unknown. Patient recovered.

Metformin Side Effects Report #5481103-X
Metformin side effect was reported by a Consumer or non-health professional from NORWAY on Dec 07, 2006. Female patient, 81 years of age, was diagnosed with type 2 diabetes mellitus, hypertension and was treated with Metformin. After drug was administered, patient experienced the following side effects: abdominal pain What is  abdominal pain, body temperature decreased, dialysis What is  dialysis, diarrhoea, haematemesis, hypotension, hypothermia What is  hypothermia, lactic acidosis, rectal haemorrhage. Metformin dosage: unknown. During the same period patient was treated with GLIMEPIRIDE, LISINOPRIL, HYDROCHLOROTHIAZIDE, CALCIUM CHANNEL BLOCKERS. Patient was hospitalized. Patient recovered.


Metformin Side Effects Report #6046232-0
Metformin side effect was reported by a Physician from GERMANY on Jan 16, 2009. Female patient, 78 years of age, weighting 187.4 lb, was diagnosed with type 2 diabetes mellitus, gastric ulcer helicobacter and was treated with Metformin. After drug was administered, patient experienced the following side effects: lactic acidosis, renal failure acute, rhabdomyolysis. Metformin dosage: unknown. During the same period patient was treated with AMOXICILLIN, METRONIDAZOLE. Patient died.

Metformin Side Effects Report #6047565-4
Metformin side effect was reported by a Health Professional from GERMANY on Jan 16, 2009. Female patient, 78 years of age, weighting 187.4 lb, was diagnosed with type 2 diabetes mellitus, gastric ulcer helicobacter and was treated with Metformin. After drug was administered, patient experienced the following side effects: lactic acidosis, renal failure acute, rhabdomyolysis. Metformin dosage: unknown. During the same period patient was treated with AMOXICILLIN, METRONIDAZOLE. Patient died.

Metformin Side Effects Report #6053199-8
Metformin side effect was reported by a Physician from GERMANY on Jan 19, 2009. Female patient, 78 years of age, weighting 187.4 lb, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: lactic acidosis, renal failure acute, rhabdomyolysis. Metformin dosage: unknown. During the same period patient was treated with METRONIDAZOLE, AMOXICILLIN. Patient died.

Metformin Side Effects Report #6060159-X
Metformin side effect was reported by a Consumer or non-health professional from GERMANY on Jan 16, 2009. Female patient, 78 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: lactic acidosis, renal failure acute, rhabdomyolysis. Metformin dosage: unknown. During the same period patient was treated with AMOXICILLIN TRIHYDRATE, METRONIDAZOLE. Patient died.

Metformin Side Effects Report #6060250-8
Metformin side effect was reported by a Health Professional from GERMANY on Jan 16, 2009. Female patient, 78 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: lactic acidosis, renal failure acute, rhabdomyolysis. Metformin dosage: unknown. During the same period patient was treated with AMOXICILLIN, METRONIDAZOLE. Patient died.


Metformin Side Effects Report #6062530-9
Metformin side effect was reported by a Health Professional from GERMANY on Jan 16, 2009. Female patient, 78 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: lactic acidosis, renal failure acute, rhabdomyolysis. Metformin dosage: unknown. During the same period patient was treated with AMOXICILLIN, METRONIDAZOLE. Patient died.

Metformin Side Effects Report #6065268-7
Metformin side effect was reported by a Consumer or non-health professional from GERMANY on Jan 16, 2009. Female patient, 78 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: lactic acidosis, renal failure acute, rhabdomyolysis. Metformin dosage: unknown. During the same period patient was treated with AMOXICILLIN, METRONIDAZOLE. Patient died.

Metformin Side Effects Report #5527514-5
Metformin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Nov 03, 2007. Female patient, 77 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: diarrhoea, haemodialysis, hypotension, lactic acidosis, malaise, renal failure acute, vomiting. Metformin dosage: unknown. Patient recovered.

Metformin Side Effects Report #5701913-0
Metformin side effect was reported by a Health Professional from UNITED STATES on Apr 09, 2008. Female patient, 77 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: cardiac arrest What is  cardiac arrest, lactic acidosis, renal failure acute. Metformin dosage: unknown. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5702346-3
Metformin side effect was reported by a Health Professional from UNITED STATES on Apr 07, 2008. Female patient, 77 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: cardiac arrest What is  cardiac arrest, lactic acidosis, renal failure acute. Metformin dosage: unknown. Patient was hospitalized. Patient recovered.


Metformin Side Effects Report #5704085-1
Metformin side effect was reported by a Health Professional from GERMANY on Apr 11, 2008. Female patient, 77 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: cardiac arrest What is  cardiac arrest, lactic acidosis, renal failure acute. Metformin dosage: unknown. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5750579-2
Metformin side effect was reported by a Health Professional from GERMANY on May 21, 2008. Female patient, 77 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: diarrhoea, hypotension, lactic acidosis, malaise, renal failure acute, vomiting. Metformin dosage: unknown. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5894641-2
Metformin side effect was reported by a Health Professional from on Sept 08, 2008. Female patient, 77 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: lactic acidosis, renal failure. Metformin dosage: unknown. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5894663-1
Metformin side effect was reported by a Health Professional from on Sept 08, 2008. Female patient, 77 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: lactic acidosis, renal failure. Metformin dosage: unknown. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5931221-4
Metformin side effect was reported by a Consumer or non-health professional from DENMARK on May 29, 2006. Female patient, 77 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: diarrhoea, haemodialysis, lactic acidosis, malaise, renal failure acute, vomiting. Metformin dosage: unknown. Patient was hospitalized. Patient recovered.


Metformin Side Effects Report #5931581-4
Metformin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Oct 27, 2006. Female patient, 77 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: acidosis, haemodialysis, hypotension, lactic acidosis, renal failure acute. Metformin dosage: 2000 MG; QD; PO. During the same period patient was treated with IV CONTRAST MEDIA. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5932510-X
Metformin side effect was reported by a Consumer or non-health professional from DENMARK on May 18, 2006. Female patient, 77 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: haemodialysis, hypotension, lactic acidosis, renal failure acute. Metformin dosage: unknown. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5933095-4
Metformin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on July 20, 2006. Female patient, 77 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: diarrhoea, haemodialysis, hypotension, lactic acidosis, renal failure acute. Metformin dosage: unknown. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #6016119-8
Metformin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Dec 08, 2008. Female patient, 77 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: diarrhoea, hypotension, lactic acidosis, malaise, renal failure acute, vomiting. Metformin dosage: (850 MG BID OR 1 G BID). Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #6101040-7
Metformin side effect was reported by a Health Professional from GERMANY on Feb 26, 2009. Female patient, 77 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: diarrhoea, hypotension, lactic acidosis, malaise, renal failure acute, vomiting. Metformin dosage: unknown. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5423498-9
Metformin side effect was reported by a Health Professional from FRANCE on Aug 09, 2007. Female patient, 76 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: hypotension, lactic acidosis, malaise, renal failure acute. Metformin dosage: unknown. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5441637-0
Metformin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Aug 14, 2007. Female patient, 76 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: apache ii score increased, haemodialysis, hypotension, lactic acidosis, malaise, renal failure acute. Metformin dosage: unknown. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5527520-0
Metformin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Nov 03, 2007. Female patient, 76 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: haemodialysis, hypotension, lactic acidosis, renal failure acute. Metformin dosage: unknown. Patient recovered.

Metformin Side Effects Report #5931229-9
Metformin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on May 18, 2006. Female patient, 76 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: haemodialysis, hypotension, lactic acidosis, renal failure acute. Metformin dosage: unknown. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5931620-0
Metformin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on May 29, 2006. Female patient, 76 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: haemodialysis, hypovolaemia, lactic acidosis, renal failure acute. Metformin dosage: unknown. During the same period patient was treated with ANGIOTENSION II, RECEPTOR BLOCKER. Patient was hospitalized. Patient recovered.


Metformin Side Effects Report #5932977-7
Metformin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on May 29, 2006. Female patient, 76 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: hypotension, lactic acidosis, renal failure acute. Metformin dosage: 2000 MG; PO. During the same period patient was treated with ANGIOTENSIN II RECEPTOR BLOCKER. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #6016301-X
Metformin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Dec 08, 2008. Female patient, 76 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: haemodialysis, hypotension, lactic acidosis, malaise, renal failure acute. Metformin dosage: (850 MG BID OR 1 G BID). During the same period patient was treated with ANGIOTENSION II RECEPTOR BLOCKER. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #6075947-3
Metformin side effect was reported by a Health Professional from UNITED KINGDOM on Feb 06, 2009. Female patient, 76 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: hypotension, lactic acidosis, malaise, renal failure acute. Metformin dosage: unknown. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #6076365-4
Metformin side effect was reported by a Health Professional from UNITED KINGDOM on Feb 06, 2009. Female patient, 76 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: hypotension, lactic acidosis, malaise, renal failure acute. Metformin dosage: unknown. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #6119711-5
Metformin side effect was reported by a Health Professional from UNITED KINGDOM on Mar 13, 2009. Female patient, 76 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: hypotension, lactic acidosis, malaise, renal failure acute. Metformin dosage: 1 DF = 850 MG OR 1G.. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #6125238-7
Metformin side effect was reported by a Health Professional from UNITED KINGDOM on Mar 13, 2009. Female patient, 76 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: hypotension, lactic acidosis, malaise, renal failure acute. Metformin dosage: unknown. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #6131117-1
Metformin side effect was reported by a Consumer or non-health professional from on Mar 16, 2009. Female patient, 76 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: haemodialysis, hypotension, lactic acidosis, renal failure acute. Metformin dosage: unknown. During the same period patient was treated with ANGIOSTENSIN II RECEPTOR BLOCKER. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5767418-6
Metformin side effect was reported by a Health Professional from GERMANY on June 03, 2008. Female patient, 75 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: lactic acidosis, renal failure acute. Metformin dosage: unknown. During the same period patient was treated with LOSARTAN POTASSIUM, PROPANOL, PANTOPRAZOLE, PAROXETINE, PREDNISONE, FRAXIPARINE, EXEMESTANE. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5823363-9
Metformin side effect was reported by a Health Professional from GERMANY on July 24, 2008. Female patient, 75 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: lactic acidosis, renal failure acute. Metformin dosage: unknown. During the same period patient was treated with LOSARTAN POTASSIUM, PROPRANOLOL, PANTOPRAZOLE, PAROXETINE, PREDNISONE, FRAXIPARINE, EXEMESTANE. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5894648-5
Metformin side effect was reported by a Health Professional from on Sept 08, 2008. Female patient, 75 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: lactic acidosis, renal failure. Metformin dosage: unknown. Patient was hospitalized. Patient recovered.


Metformin Side Effects Report #5581039-X
Metformin side effect was reported by a Physician from SPAIN on Dec 14, 2007. Female patient, 74 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: anuria, confusional state, dehydration, disorientation, heart rate increased, kussmaul respiration, lactic acidosis, overdose, pancreatitis acute. Metformin dosage: 850 MG, TID. During the same period patient was treated with GLYBURIDE. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5589514-9
Metformin side effect was reported by a Physician from SPAIN on Jan 03, 2008. Female patient, 74 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: anuria, confusional state, dehydration, disorientation, gastrointestinal hypomotility, kussmaul respiration, lactic acidosis, pancreatitis acute, rectal adenoma. Metformin dosage: 850 MG, TID. During the same period patient was treated with GLYBURIDE. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5623889-7
Metformin side effect was reported by a Physician from SPAIN on Jan 28, 2008. Female patient, 74 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: anuria, confusional state, dehydration, gastrointestinal hypomotility, kussmaul respiration, lactic acidosis, pancreatitis acute, rectal adenoma, tachycardia. Metformin dosage: 850 MG, TID,. During the same period patient was treated with GLYBURIDE. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5894643-6
Metformin side effect was reported by a Health Professional from on Sept 08, 2008. Female patient, 74 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: lactic acidosis. Metformin dosage: unknown. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5380984-8
Metformin side effect was reported by a Health Professional from GERMANY on June 27, 2007. Female patient, 73 years of age, was diagnosed with type 2 diabetes mellitus, blood pressure increased, hypertension, prophylaxis, hypercholesterolaemia and was treated with Metformin. After drug was administered, patient experienced the following side effects: lactic acidosis, renal failure acute. Metformin dosage: unknown. During the same period patient was treated with GLIPIZIDE, PERINDOPRIL ERBUMINE, AMLODIPINE, ASPIRIN, OMEPRAZOLE, PRAVASTATIN. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5383619-3
Metformin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on June 27, 2007. Female patient, 73 years of age, was diagnosed with type 2 diabetes mellitus, blood pressure increased and was treated with Metformin. After drug was administered, patient experienced the following side effects: lactic acidosis, renal failure acute. Metformin dosage: 1500 MG (500 MG, 3 IN 1 D) ORAL. During the same period patient was treated with INDAPAMIDE W, GLIPIZIDE. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5385140-5
Metformin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on June 27, 2007. Female patient, 73 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: lactic acidosis, renal failure acute. Metformin dosage: 500 MG; TID; PO. During the same period patient was treated with PERINDOPRIL, GLIPIZIDE, AMLODIPINE, PRAVASTATIN, OMEPRAZOLE, ASPIRIN. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5385940-1
Metformin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on June 27, 2007. Female patient, 73 years of age, weighting 119.0 lb, was diagnosed with type 2 diabetes mellitus, blood pressure increased and was treated with Metformin. After drug was administered, patient experienced the following side effects: lactic acidosis, renal failure acute. Metformin dosage: 500 MG , TID, ORAL. During the same period patient was treated with COVERSYL, GLIPIZIDE, AMLODIPINE, ASPIRIN, OMEPRAZOLE, PRAVASTATIN. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5391787-2
Metformin side effect was reported by a Health Professional from UNITED STATES on July 02, 2007. Female patient, 73 years of age, weighting 119.0 lb, was diagnosed with type 2 diabetes mellitus, blood pressure increased and was treated with Metformin. After drug was administered, patient experienced the following side effects: lactic acidosis, renal failure acute. Metformin dosage: 500 MG, TID, ORAL. During the same period patient was treated with PERINDOPRIL ERBUMINE, GLIPIZIDE, AMLODIPINE MALEATE, ASPIRIN, OMEPRAZOLE, PRAVASTATIN. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5518036-6
Metformin side effect was reported by a Health Professional from UNITED KINGDOM on Nov 08, 2007. Male patient, 73 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: confusional state, haemodialysis, hypotension, lactic acidosis, renal failure acute, vomiting. Metformin dosage: unknown. Patient was hospitalized. Patient recovered.


Metformin Side Effects Report #5527518-2
Metformin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Nov 03, 2007. Male patient, 73 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: confusional state, haemodialysis, hypotension, lactic acidosis, renal failure acute. Metformin dosage: unknown. Patient recovered.

Metformin Side Effects Report #5527614-X
Metformin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Nov 03, 2007. Female patient, 73 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: diarrhoea, haemodialysis, hypotension, lactic acidosis, lethargy, renal failure acute. Metformin dosage: unknown. Patient recovered.

Metformin Side Effects Report #5603331-2
Metformin side effect was reported by a Consumer or non-health professional from DENMARK on Jan 09, 2008. Female patient, 73 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: anuria, discomfort, dyspnoea, influenza like illness, lactic acidosis, pneumonia What is  pneumonia, shock. Metformin dosage: 500 MG;BID;PO. Patient was hospitalized. Patient died on 01/03/2008.

Metformin Side Effects Report #5742180-1
Metformin side effect was reported by a Health Professional from GERMANY on May 12, 2008. Female patient, 73 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: lactic acidosis, renal failure acute. Metformin dosage: unknown. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5931036-7
Metformin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on May 18, 2006. Male patient, 73 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: confusional state, haemodialysis, hypotension, lactic acidosis, renal failure acute, vomiting. Metformin dosage: unknown. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5931219-6
Metformin side effect was reported by a Consumer or non-health professional from DENMARK on May 29, 2006. Female patient, 73 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: diarrhoea, haemodialysis, lactic acidosis, lethargy, renal failure acute. Metformin dosage: unknown. During the same period patient was treated with RECEPTOR BLOCKER. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5931225-1
Metformin side effect was reported by a Consumer or non-health professional from DENMARK on May 29, 2006. Male patient, 73 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: confusional state, haemodialysis, lactic acidosis, renal failure acute, vomiting. Metformin dosage: unknown. During the same period patient was treated with NSAIDS. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5931587-5
Metformin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on May 29, 2006. Female patient, 73 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: haemodialysis, hypotension, lactic acidosis, renal failure acute. Metformin dosage: 2000 MG; PO. During the same period patient was treated with ANGIOTENSION II, RECEPTOR BLOCKER. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5931634-0
Metformin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on May 29, 2006. Female patient, 73 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: haemodialysis, hypotension, lactic acidosis, renal failure acute. Metformin dosage: unknown. During the same period patient was treated with ANGIOTENSION II, RECEPTOR BLOCKER. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5932461-0
Metformin side effect was reported by a Health Professional from UNITED KINGDOM on Oct 27, 2006. Male patient, 73 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: confusional state, haemodialysis, hypotension, lactic acidosis, renal failure acute, vomiting. Metformin dosage: 2000 MG; PO. Patient was hospitalized. Patient recovered.


Metformin Side Effects Report #6016046-6
Metformin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Dec 08, 2008. Male patient, 73 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: confusional state, haemodialysis, hypotension, hypovolaemia, hypoxia, lactic acidosis, malaise, renal failure acute, vomiting. Metformin dosage: (850 MG BID OR 1 G BID). During the same period patient was treated with NSAID. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #6016271-4
Metformin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Dec 08, 2008. Female patient, 73 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: diarrhoea, haemodialysis, hypotension, lactic acidosis, lethargy, malaise, renal failure acute. Metformin dosage: (850 MG BID OR 1 G BID). During the same period patient was treated with ANGIOTENSION II RECEPTOR BLOCKER. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #6076553-7
Metformin side effect was reported by a Health Professional from GERMANY on Feb 06, 2009. Female patient, 73 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: diarrhoea, lactic acidosis, lethargy, renal failure acute. Metformin dosage: 1 FORM=850MG OR 1G DAILY. FORMULATION: TABS. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #6131690-3
Metformin side effect was reported by a Health Professional from GERMANY on Mar 23, 2009. Male patient, 73 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: confusional state, hypotension, lactic acidosis, renal failure acute, vomiting. Metformin dosage: 1 FORM= 850 MG OR 1 G. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5894645-X
Metformin side effect was reported by a Health Professional from on Sept 08, 2008. Male patient, 72 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: lactic acidosis, renal failure. Metformin dosage: unknown. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #6009089-X
Metformin side effect was reported by a Health Professional from NETHERLANDS on Dec 03, 2008. Male patient, 72 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: abdominal discomfort, catheter sepsis, coma, continuous haemodiafiltration, extremity necrosis, haemodynamic instability, ileus, lactic acidosis, pneumonia What is  pneumonia. Metformin dosage: (1000 MG TID). During the same period patient was treated with TOLBUTAMIDE, SIMVASTATIN, HYDROCHLOROTHIAZIDE, ENALAPRIL MALEATE. Patient was hospitalized. Patient died on 01/01/2007.

Metformin Side Effects Report #5389017-0
Metformin side effect was reported by a Health Professional from GERMANY on July 09, 2007. Male patient, 71 years of age, was diagnosed with type 2 diabetes mellitus, diabetic neuropathy, urinary tract infection What is  urinary tract infection and was treated with Metformin. After drug was administered, patient experienced the following side effects: cardio-respiratory arrest, lactic acidosis, multi-organ failure. Metformin dosage: unknown. During the same period patient was treated with SOLOSA, LYRICA, CIPROXIN, MAALOX FAST BLOCKER, CETIRIZINE. Patient was hospitalized. Patient died on 06/22/2007.

Metformin Side Effects Report #5407729-7
Metformin side effect was reported by a Consumer or non-health professional from ITALY on July 09, 2007. Male patient, 71 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: cardio-respiratory arrest, coagulopathy, diarrhoea, dysarthria, lactic acidosis, metabolic acidosis, multi-organ failure. Metformin dosage: 1000 MG, ORAL. During the same period patient was treated with SOLOSA, LYRICA, CIPROXIN, MAALOX, CETIRIZINE. Patient was hospitalized. Patient died.

Metformin Side Effects Report #5531400-4
Metformin side effect was reported by a Health Professional from ITALY on Nov 23, 2007. Male patient, 71 years of age, was diagnosed with type 2 diabetes mellitus, diabetic neuropathy, urinary tract infection What is  urinary tract infection and was treated with Metformin. After drug was administered, patient experienced the following side effects: cardio-respiratory arrest, lactic acidosis, multi-organ failure. Metformin dosage: unknown. During the same period patient was treated with SOLOSA, LYRICA, CIPROXIN, MAALOX, CETIRIZINE. Patient was hospitalized. Patient died on 06/22/2007.

Metformin Side Effects Report #5788980-3
Metformin side effect was reported by a Pharmacist from UNITED STATES on June 25, 2008. Male patient, 71 years of age, was diagnosed with type 2 diabetes mellitus, oedema and was treated with Metformin. After drug was administered, patient experienced the following side effects: acute prerenal failure, blood glucose decreased, lactic acidosis, loss of consciousness, mental status changes, metabolic acidosis, renal failure acute. Metformin dosage: ORAL;1000.0 MILLIGRAM. During the same period patient was treated with FUROSEMIDE, GEMFIBROZIL, OMEPRAZOLE, FELODIPINE, SIMVASTATIN, LISINOPRIL. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5390208-3
Metformin side effect was reported by a Consumer or non-health professional from GERMANY on June 09, 2004. Male patient, 70 years of age, was diagnosed with type 2 diabetes mellitus, pain What is  pain and was treated with Metformin. After drug was administered, patient experienced the following side effects: duodenal ulcer haemorrhage, gastric ulcer haemorrhage, lactic acidosis, renal failure acute. Metformin dosage: unknown. During the same period patient was treated with IBUPROFEN, DICLOFENAC, GLIBENCLAMIDE. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5427616-8
Metformin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on June 09, 2004. Male patient, 70 years of age, was diagnosed with type 2 diabetes mellitus, pain What is  pain and was treated with Metformin. After drug was administered, patient experienced the following side effects: duodenal ulcer haemorrhage, gastric ulcer haemorrhage, lactic acidosis, reflux oesophagitis, renal failure acute. Metformin dosage: unknown. During the same period patient was treated with IBUPROFEN, DICLOFENAC, GLYBURIDE. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5527607-2
Metformin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Nov 03, 2007. Female patient, 70 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: haemodialysis, hypotension, lactic acidosis, lethargy, renal failure acute, somnolence. Metformin dosage: unknown. Patient recovered.

Metformin Side Effects Report #5752052-4
Metformin side effect was reported by a Health Professional from GERMANY on May 20, 2008. Female patient, 70 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: lactic acidosis, renal failure acute. Metformin dosage: unknown. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5822602-8
Metformin side effect was reported by a Health Professional from SPAIN on July 21, 2008. Male patient, 70 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: hypotension, lactic acidosis, multi-organ failure. Metformin dosage: unknown. Patient was hospitalized. Patient died.

Metformin Side Effects Report #5894630-8
Metformin side effect was reported by a Health Professional from on Sept 08, 2008. Male patient, 70 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: lactic acidosis, renal failure. Metformin dosage: unknown. Patient was hospitalized. Patient died.

Metformin Side Effects Report #5894651-5
Metformin side effect was reported by a Health Professional from on Sept 08, 2008. Female patient, 70 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: lactic acidosis. Metformin dosage: unknown. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5931045-8
Metformin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on May 29, 2006. Female patient, 70 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: haemodialysis, hypotension, lactic acidosis, renal failure acute. Metformin dosage: 2000 MG; PO. During the same period patient was treated with ANGIOTENSIN CONVERTING ENZYME INHIBITOR. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5931571-1
Metformin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on May 19, 2006. Female patient, 70 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: lactic acidosis, lethargy, renal failure acute, somnolence. Metformin dosage: unknown. During the same period patient was treated with ACE INHIBITOR. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #5931709-6
Metformin side effect was reported by a Consumer or non-health professional from DENMARK on May 18, 2006. Female patient, 70 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: diarrhoea, haemodialysis, hypertension, hypotension, lactic acidosis, myocardial ischaemia, renal failure acute. Metformin dosage: unknown. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #6016283-0
Metformin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Dec 08, 2008. Female patient, 70 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: haemodialysis, hypotension, lactic acidosis, lethargy, malaise, renal failure acute, somnolence. Metformin dosage: (850 MG BID OR 1 G BID). During the same period patient was treated with ACE INHIBITOR NOS, NSAID. Patient was hospitalized. Patient recovered.

Metformin Side Effects Report #6138457-0
Metformin side effect was reported by a Health Professional from GERMANY on Mar 26, 2009. Female patient, 70 years of age, was diagnosed with type 2 diabetes mellitus and was treated with Metformin. After drug was administered, patient experienced the following side effects: lactic acidosis, renal failure acute. Metformin dosage: unknown. During the same period patient was treated with ANGIOTENSIN CONVERTING ENZYME. Patient was hospitalized. Patient recovered.
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side effects of Metformin