Leucovorin and disease progression Patient Reports February 11, 2012

Leucovorin Side Effects Report #5876153-5
Leucovorin side effect was reported by a Health Professional from UNITED STATES on Aug 27, 2008. Male patient, 56 years of age, was diagnosed with neoplasm and was treated with Leucovorin. After drug was administered, patient experienced the following side effects: blood creatinine increased, blood urea increased, disease progression, malignant ascites. Leucovorin dosage: unknown. Patient was hospitalized. Patient recovered.

Leucovorin Side Effects Report #6002026-3
Leucovorin side effect was reported by a Health Professional from UNITED STATES on Dec 01, 2008. Male patient, 56 years of age, was diagnosed with neoplasm and was treated with Leucovorin. After drug was administered, patient experienced the following side effects: ascites, blood creatinine increased, blood urea increased, cytology abnormal, disease progression. Leucovorin dosage: unknown. Patient was hospitalized. Patient recovered.

Leucovorin Side Effects Report #6002027-5
Leucovorin side effect was reported by a Health Professional from UNITED STATES on Dec 01, 2008. Male patient, 56 years of age, was diagnosed with neoplasm and was treated with Leucovorin. After drug was administered, patient experienced the following side effects: ascites, blood creatinine increased, blood urea nitrogen/creatinine ratio increased, disease progression, neoplasm malignant. Leucovorin dosage: unknown. Patient was hospitalized. Patient recovered.

Leucovorin Side Effects Report #5420370-5
Leucovorin side effect was reported by a Physician from UNITED STATES on Aug 03, 2007. Male patient, 16 years of age, was diagnosed with nasopharyngeal cancer stage iii and was treated with Leucovorin. After drug was administered, patient experienced the following side effects: blood luteinising hormone decreased, disease progression, dry mouth, hypothyroidism, myopia, otorrhoea, psychotic disorder . Leucovorin dosage: 25 MG/M2 PER_CYCLE. During the same period patient was treated with METHOTREXATE, CISPLATIN, FLUOROURACIL. Patient recovered.


Leucovorin Side Effects Report #6112183-6
Leucovorin side effect was reported by a Health Professional from UNITED STATES on Feb 13, 2009. Male patient, 70 years of age, was diagnosed with colorectal cancer stage i and was treated with Leucovorin. After drug was administered, patient experienced the following side effects: culture urine positive, cystitis, dehydration, disease progression, neutropenia, pseudomonas infection, urinary tract infection , urine ketone body present. Leucovorin dosage: unknown. During the same period patient was treated with FLUOROURACIL, OXALIPLATINECTION, CHLORPROMAZINE, FENTANYL. Patient was hospitalized. Patient recovered.

Leucovorin Side Effects Report #6130946-8
Leucovorin side effect was reported by a Physician from UNITED STATES on Mar 13, 2009. Female patient, 78 years of age, was diagnosed with colorectal cancer metastatic and was treated with Leucovorin. After drug was administered, patient experienced the following side effects: blood urine present, diarrhoea, disease progression. Leucovorin dosage: unknown. During the same period patient was treated with AVASTIN, FLUOROURACIL, ELOXATIN. Patient died on 03/12/2009.

Leucovorin Side Effects Report #5358006-4
Leucovorin side effect was reported by a Health Professional from UNITED STATES on May 31, 2007. Male patient, 46 years of age, was diagnosed with colorectal cancer metastatic and was treated with Leucovorin. After drug was administered, patient experienced the following side effects: disease progression. Leucovorin dosage: 808 MG IV. Patient was hospitalized. Patient died on 08/10/2006.

Leucovorin Side Effects Report #4864064-3
Leucovorin side effect was reported by a Health Professional from CANADA on Dec 06, 2005. Female patient, 46 years of age, weighting 114.0 lb, was diagnosed with colorectal cancer metastatic and was treated with Leucovorin. After drug was administered, patient experienced the following side effects: diarrhoea, disease progression, rectal haemorrhage. Leucovorin dosage: 33MG IV. Patient was hospitalized. Patient died on 06/22/2004.

Leucovorin Side Effects Report #4562057-7
Leucovorin side effect was reported by a Physician from on Jan 13, 2005. Female patient was diagnosed with colorectal cancer  and was treated with Leucovorin. After drug was administered, patient experienced the following side effects: disease progression, respiratory failure, sepsis . Leucovorin dosage: 200 MG/M2, DAY + DAY 2; REPEATED EVERY 2 WEEKS, INTRAVENOUS INFUSION. During the same period patient was treated with FLUOROURACIL. Patient died.


Leucovorin Side Effects Report #4562058-9
Leucovorin side effect was reported by a Physician from on Jan 13, 2005. Female patient was diagnosed with colorectal cancer  and was treated with Leucovorin. After drug was administered, patient experienced the following side effects: colorectal cancer , disease progression. Leucovorin dosage: 200 MG/M2, DAY + DAY 2; REPEATED EVERY 2 WEEKS, INTRAVENOUS INFUSION. During the same period patient was treated with FLUOROURACIL. Patient died.

Leucovorin Side Effects Report #5088653-9
Leucovorin side effect was reported by a Consumer or non-health professional from UNITED STATES on July 28, 2006. Male patient, 80 years of age, weighting 125.7 lb, was diagnosed with biliary neoplasm and was treated with Leucovorin. After drug was administered, patient experienced the following side effects: anaemia, asthenia, dehydration, disease progression, hypokalaemia, hyponatraemia, mucosal inflammation, oral intake reduced. Leucovorin dosage: 25 MG/M2, QDX5, INTRAVENOUS. During the same period patient was treated with FLUOROURACIL, DOXAZOSIN, OXYCODONE, REGLAN. Patient was hospitalized. Patient died on 03/22/2006.

Leucovorin Side Effects Report #5090078-7
Leucovorin side effect was reported by a Health Professional from UNITED STATES on Aug 10, 2006. Male patient, 80 years of age, weighting 125.7 lb, was diagnosed with biliary neoplasm and was treated with Leucovorin. After drug was administered, patient experienced the following side effects: asthenia, dehydration, disease progression, mucosal inflammation, oral intake reduced, oral pain, pharyngolaryngeal pain. Leucovorin dosage: 25MG/M2/QDX5/IV. Patient was hospitalized. Patient died on 03/22/2006.

Leucovorin Side Effects Report #5245951-3
Leucovorin side effect was reported by a Physician from SPAIN on Feb 02, 2007. Male patient, 76 years of age, weighting 163.1 lb, was diagnosed with biliary neoplasm and was treated with Leucovorin. After drug was administered, patient experienced the following side effects: blood bicarbonate decreased, blood creatinine increased, disease progression, hyperglycaemia, mucosal inflammation. Leucovorin dosage: 25 MG/M2 OTH IV. During the same period patient was treated with FLUOROURACIL, PANTOPRAZOLE, METAMIZOLE, INDAPAMIDE, ACETYLSALICYLIC ACID SRT, MEGESTROL ACETATE, FUROSEMIDE, ACETYLCYSTEIN. Patient was hospitalized. Patient died on 10/23/2006.

Leucovorin Side Effects Report #4621547-9
Leucovorin side effect was reported by a Physician from on June 15, 2004. Male patient, 70 years of age, was treated with Leucovorin. After drug was administered, patient experienced the following side effects: anorexia, disease progression, leukopenia, metastases to lymph nodes, neoplasm recurrence, pyrexia. Leucovorin dosage: 20 MG/M2; IV. During the same period patient was treated with NEDAPLATIN, FLUOROURACIL. Patient recovered.


Leucovorin Side Effects Report #5241786-6
Leucovorin side effect was reported by a Health Professional from JAPAN on Feb 15, 2007. Male patient was diagnosed with rectal cancer and was treated with Leucovorin. After drug was administered, patient experienced the following side effects: cystitis, disease progression. Leucovorin dosage: 100MG/BODY. During the same period patient was treated with FLUOROURACIL, OXALIPLATIN. Patient recovered.

Leucovorin Side Effects Report #5325515-3
Leucovorin side effect was reported by a Health Professional from UNITED KINGDOM on May 11, 2007. Male patient, weighting 182.3 lb, was diagnosed with neurological symptom and was treated with Leucovorin. After drug was administered, patient experienced the following side effects: diarrhoea, disease progression, fibrin d dimer increased, pulmonary embolism . Leucovorin dosage: unknown. During the same period patient was treated with FLUOROURACIL, OXALIPLATIN. Patient was hospitalized. Patient recovered.

Leucovorin Side Effects Report #5182902-4
Leucovorin side effect was reported by a Health Professional from JAPAN on Feb 21, 2006. Male patient, weighting 116.8 lb, was diagnosed with colon cancer and was treated with Leucovorin. After drug was administered, patient experienced the following side effects: anorexia, cardio-respiratory arrest, decreased appetite, dehydration, diarrhoea, disease progression, haemoglobin decreased, post procedural haemorrhage. Leucovorin dosage: unknown. During the same period patient was treated with FLUOROURACIL, OXALIPLATIN. Patient was hospitalized. Patient died on 10/27/2005.

Leucovorin Side Effects Report #5811769-3
Leucovorin side effect was reported by a Consumer or non-health professional from UNITED STATES on July 15, 2008. Female patient, weighting 175.3 lb, was treated with Leucovorin. After drug was administered, patient experienced the following side effects: confusional state, disease progression. Leucovorin dosage: 5597 MG. During the same period patient was treated with METHOTREXATE, TEMOZOLOMIDE. Patient was hospitalized. Patient recovered.