Leucovorin and anorexia Patient Reports February 11, 2012

Leucovorin Side Effects Report #4602940-7
Leucovorin side effect was reported by a Consumer or non-health professional from on Feb 18, 2005. Female patient, 57 years of age, was diagnosed with rectosigmoid cancer and was treated with Leucovorin. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, anorexia, aspartate aminotransferase increased, blood lactate dehydrogenase increased, liver disorder, malaise. Leucovorin dosage: 75 MG QD. During the same period patient was treated with TEGAFUR URACIL. Patient recovered.

Leucovorin Side Effects Report #4630161-0
Leucovorin side effect was reported by a Health Professional from on Feb 18, 2005. Female patient, 57 years of age, was diagnosed with rectosigmoid cancer and was treated with Leucovorin. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, anorexia, aspartate aminotransferase increased, blood lactate dehydrogenase increased, diarrhoea, epigastric discomfort, liver disorder, malaise. Leucovorin dosage: 75 MG QD PO. During the same period patient was treated with TEGAFUR URACIL. Patient recovered.

Leucovorin Side Effects Report #4640754-2
Leucovorin side effect was reported by a Consumer or non-health professional from on Feb 18, 2005. Female patient, 57 years of age, was diagnosed with rectosigmoid cancer and was treated with Leucovorin. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, anorexia, aspartate aminotransferase increased, blood lactate dehydrogenase increased, diarrhoea, eosinophil percentage increased, epigastric discomfort, liver disorder, malaise. Leucovorin dosage: 75 MG QD PO. During the same period patient was treated with TEGAFUR URACIL. Patient recovered.

Leucovorin Side Effects Report #4589261-6
Leucovorin side effect was reported by a Health Professional from on Feb 04, 2005. Female patient, 51 years of age, weighting 115.7 lb, was diagnosed with rectal cancer metastatic and was treated with Leucovorin. After drug was administered, patient experienced the following side effects: anorexia, diarrhoea, white blood cell count decreased. Leucovorin dosage: 75 MG/DAY, PO. During the same period patient was treated with IRINOTECAN. Patient was hospitalized. Patient recovered.


Leucovorin Side Effects Report #4698845-6
Leucovorin side effect was reported by a Consumer or non-health professional from on June 06, 2005. Male patient, 80 years of age, was diagnosed with rectal cancer and was treated with Leucovorin. After drug was administered, patient experienced the following side effects: anorexia, diarrhoea, malaise, metastases to liver, refusal of treatment by patient, weight decreased. Leucovorin dosage: 75 MG/DAY, PO. During the same period patient was treated with IRINOTECAN, MAGNESIUM OXIDE. Patient was hospitalized. Patient recovered.

Leucovorin Side Effects Report #4600588-1
Leucovorin side effect was reported by a Health Professional from on Feb 28, 2005. Male patient, 74 years of age, was diagnosed with rectal cancer and was treated with Leucovorin. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, anorexia, blood alkaline phosphatase increased, diarrhoea, dysgeusia, gamma-glutamyltransferase increased, jaundice , malignant neoplasm progression, metastases to liver. Leucovorin dosage: 75 MG/DAY/CYCLE, PO. During the same period patient was treated with FAMOTIDINE. Patient was hospitalized. Patient died on 12/28/2004.

Leucovorin Side Effects Report #4631677-3
Leucovorin side effect was reported by a Health Professional from on Apr 04, 2005. Male patient, 70 years of age, was diagnosed with rectal cancer and was treated with Leucovorin. After drug was administered, patient experienced the following side effects: anorexia, haemoglobin decreased, oral mucosal discolouration, stomatitis. Leucovorin dosage: unknown. During the same period patient was treated with MAGNESIUM OXIDE. Patient recovered.

Leucovorin Side Effects Report #4629318-4
Leucovorin side effect was reported by a Health Professional from on Apr 01, 2005. Male patient, 63 years of age, was diagnosed with rectal cancer and was treated with Leucovorin. After drug was administered, patient experienced the following side effects: acute myocardial infarction, alanine aminotransferase increased, anorexia, aspartate aminotransferase increased, blood creatine phosphokinase increased, blood lactate dehydrogenase increased, dehydration, diarrhoea, haemoglobin abnormal. Leucovorin dosage: 75 MG/DAY/CYCLE (NR), PO. Patient recovered.

Leucovorin Side Effects Report #4627296-5
Leucovorin side effect was reported by a Physician from on Feb 23, 2005. Male patient was diagnosed with rectal cancer and was treated with Leucovorin. After drug was administered, patient experienced the following side effects: acute myocardial infarction, anorexia, diarrhoea, lymphocyte count decreased, neoplasm recurrence, rectal cancer. Leucovorin dosage: 75 MG/DAY/CYCLE. Patient recovered.


Leucovorin Side Effects Report #4629027-1
Leucovorin side effect was reported by a Physician from on Apr 04, 2005. Male patient was diagnosed with rectal cancer and was treated with Leucovorin. After drug was administered, patient experienced the following side effects: anorexia, haemoglobin decreased, stomatitis. Leucovorin dosage: 75 MG/DAY. During the same period patient was treated with LEUCOVORIN CALCIUM, MAGNESIUM OXIDE. Patient recovered.

Leucovorin Side Effects Report #5080434-5
Leucovorin side effect was reported by a Physician from JAPAN on July 11, 2006. Male patient, weighting 158.7 lb, was diagnosed with large intestine carcinoma and was treated with Leucovorin. After drug was administered, patient experienced the following side effects: anorexia, haemoglobin decreased, leukopenia, neutropenia, pneumonia , pulmonary oedema, thrombocytopenia. Leucovorin dosage: 175MG/BODY=99.4MG/M2. During the same period patient was treated with FLUOROURACIL, OXALIPLATIN, KYTRIL, DECADRON. Patient died on 06/22/2006.

Leucovorin Side Effects Report #4750114-1
Leucovorin side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 18, 2005. Male patient, weighting 215.8 lb, was diagnosed with gastric cancer and was treated with Leucovorin. After drug was administered, patient experienced the following side effects: abdominal distension, abdominal pain , anorexia, diarrhoea, diverticulitis, gallbladder disorder, gastrointestinal disorder, mucosal inflammation, pancytopenia. Leucovorin dosage: unknown. During the same period patient was treated with FLUOROURACIL. Patient was hospitalized. Patient recovered.

Leucovorin Side Effects Report #5545254-3
Leucovorin side effect was reported by a Health Professional from UNITED STATES on Aug 21, 2007. Female patient, 77 years of age, was diagnosed with colorectal cancer metastatic and was treated with Leucovorin. After drug was administered, patient experienced the following side effects: anorexia, asthenia, dehydration. Leucovorin dosage: 712 MG INTRAVENOUSLY EVERY 2 W. Patient was hospitalized. Patient recovered.

Leucovorin Side Effects Report #5083640-9
Leucovorin side effect was reported by a Physician from UNITED STATES on Aug 07, 2006. Male patient, 78 years of age, was diagnosed with colon cancer and was treated with Leucovorin. After drug was administered, patient experienced the following side effects: anorexia, cholecystitis, cholelithiasis, diarrhoea, dysphagia, gastrointestinal pain, hypoxia, lethargy, lung infiltration. Leucovorin dosage: 400 MG/M2/Q2W/IV. Patient was hospitalized. Patient recovered.


Leucovorin Side Effects Report #4765421-6
Leucovorin side effect was reported by a Consumer or non-health professional from JAPAN on Aug 24, 2005. Male patient, 78 years of age, was diagnosed with colon cancer and was treated with Leucovorin. After drug was administered, patient experienced the following side effects: abdominal pain upper, anorexia, diarrhoea, metastases to liver, nausea , red blood cell count decreased, stomatitis. Leucovorin dosage: 75 MG, PO. Patient was hospitalized. Patient recovered.

Leucovorin Side Effects Report #4628170-0
Leucovorin side effect was reported by a Consumer or non-health professional from on Mar 15, 2004. Female patient, 63 years of age, was diagnosed with colon cancer and was treated with Leucovorin. After drug was administered, patient experienced the following side effects: anorexia, diarrhoea, nausea , oedema peripheral, stomatitis. Leucovorin dosage: 75 MG PO. During the same period patient was treated with TEGAFUR URACIL. Patient recovered.

Leucovorin Side Effects Report #4621547-9
Leucovorin side effect was reported by a Physician from on June 15, 2004. Male patient, 70 years of age, was treated with Leucovorin. After drug was administered, patient experienced the following side effects: anorexia, disease progression, leukopenia, metastases to lymph nodes, neoplasm recurrence, pyrexia. Leucovorin dosage: 20 MG/M2; IV. During the same period patient was treated with NEDAPLATIN, FLUOROURACIL. Patient recovered.

Leucovorin Side Effects Report #5423931-2
Leucovorin side effect was reported by a Health Professional from JAPAN on Aug 17, 2007. Male patient, 67 years of age, weighting 143.3 lb, was diagnosed with colon cancer and was treated with Leucovorin. After drug was administered, patient experienced the following side effects: anorexia, gastric ulcer. Leucovorin dosage: unknown. During the same period patient was treated with FLUOROURACIL, OXALIPLATIN. Patient was hospitalized. Patient recovered.

Leucovorin Side Effects Report #5545248-8
Leucovorin side effect was reported by a Health Professional from UNITED STATES on Apr 13, 2007. Male patient, 55 years of age, was treated with Leucovorin. After drug was administered, patient experienced the following side effects: anorexia, dehydration, laboratory test abnormal. Leucovorin dosage: 30 MG IV 5/4 WEEK. Patient was hospitalized. Patient recovered.


Leucovorin Side Effects Report #5182902-4
Leucovorin side effect was reported by a Health Professional from JAPAN on Feb 21, 2006. Male patient, weighting 116.8 lb, was diagnosed with colon cancer and was treated with Leucovorin. After drug was administered, patient experienced the following side effects: anorexia, cardio-respiratory arrest, decreased appetite, dehydration, diarrhoea, disease progression, haemoglobin decreased, post procedural haemorrhage. Leucovorin dosage: unknown. During the same period patient was treated with FLUOROURACIL, OXALIPLATIN. Patient was hospitalized. Patient died on 10/27/2005.

Leucovorin Side Effects Report #4597550-4
Leucovorin side effect was reported by a Consumer or non-health professional from on Feb 28, 2005. Female patient, weighting 106.0 lb, was treated with Leucovorin. After drug was administered, patient experienced the following side effects: abdominal pain , anorexia, biliary dilatation, dehydration, diarrhoea, hepatitis , lymphopenia, muscular weakness, nausea . Leucovorin dosage: 500 MG /M2 IV OVER 2 HOURS ON DAY 1 WEEKLY X 6 , EVERY 8 WEEKS FOR 3 CYCLES. During the same period patient was treated with FLUOROURACIL. Patient recovered.