Letrozole and osteonecrosis Patient Reports February 11, 2012

Letrozole Side Effects Report #5229770-X
Letrozole side effect was reported by a Physician from AUSTRALIA on Jan 25, 2007. Female patient, 55 years of age, was diagnosed with breast cancer recurrent and was treated with Letrozole. After drug was administered, patient experienced the following side effects: arthralgia, osteonecrosis . Letrozole dosage: 2.5 MG, QD. Patient recovered.

Letrozole Side Effects Report #5034310-4
Letrozole side effect was reported by a Physician from UNITED KINGDOM on May 19, 2006. Female patient, 69 years of age, was diagnosed with breast cancer metastatic, metastases to bone and was treated with Letrozole. After drug was administered, patient experienced the following side effects: osteonecrosis , tooth extraction. Letrozole dosage: 2.5 MG. During the same period patient was treated with ZOMETA. Patient was hospitalized and became disabled. Patient recovered.

Letrozole Side Effects Report #4865952-4
Letrozole side effect was reported by a Physician from UNITED STATES on Dec 16, 2005. Female patient, 58 years of age, weighting 199.5 lb, was diagnosed with breast cancer metastatic and was treated with Letrozole. After drug was administered, patient experienced the following side effects: bone disorder, osteonecrosis , pain in jaw, tooth extraction. Letrozole dosage: 2.5 MG, QD. During the same period patient was treated with ZOLEDRONIC ACID, BEVACIZUMAB, HYDROCHLOROTHIAZIDE, TOPROL, CALCIUM GLUCONATE, PERCOCET. Patient recovered.

Letrozole Side Effects Report #5448248-1
Letrozole side effect was reported by a Physician from BELGIUM on Aug 31, 2007. Female patient, 76 years of age, weighting 165.3 lb, was diagnosed with breast cancer , prophylaxis, diabetes mellitus and was treated with Letrozole. After drug was administered, patient experienced the following side effects: osteonecrosis . Letrozole dosage: 2.5 MG, QD. During the same period patient was treated with ZOLEDRONIC ACID, CACIT VITAMINE D3, GLUCINAN. Patient recovered.


Letrozole Side Effects Report #5485027-3
Letrozole side effect was reported by a Physician from BELGIUM on Oct 03, 2007. Female patient, 76 years of age, weighting 165.3 lb, was diagnosed with breast cancer , prophylaxis, diabetes mellitus and was treated with Letrozole. After drug was administered, patient experienced the following side effects: abdominal discomfort, dental fistula, oedema mouth, osteonecrosis , primary sequestrum, stomatitis, tooth abscess, tooth extraction. Letrozole dosage: 2.5 MG, QD. During the same period patient was treated with ZOLEDRONIC ACID, CACIT VITAMINE D3, GLUCINAN. Patient recovered.

Letrozole Side Effects Report #5553643-6
Letrozole side effect was reported by a Physician from BELGIUM on Dec 03, 2007. Female patient, 76 years of age, weighting 165.3 lb, was diagnosed with breast cancer , prophylaxis, diabetes mellitus and was treated with Letrozole. After drug was administered, patient experienced the following side effects: abdominal discomfort, dental fistula, oedema mouth, osteonecrosis , primary sequestrum, stomatitis, tooth abscess, tooth extraction. Letrozole dosage: 2.5 MG, QD. During the same period patient was treated with ZOLEDRONIC ACID, CACIT VITAMINE D3, GLUCINAN. Patient recovered.

Letrozole Side Effects Report #5227446-6
Letrozole side effect was reported by a Physician from BELGIUM on Jan 22, 2007. Female patient, 65 years of age, weighting 162.7 lb, was diagnosed with breast cancer , prophylaxis and was treated with Letrozole. After drug was administered, patient experienced the following side effects: bone disorder, gingival disorder, osteonecrosis . Letrozole dosage: 2.5 MG, QD. During the same period patient was treated with ZOLEDRONIC ACID, ASPIRIN, CACIT VITAMINE D3. Patient recovered.

Letrozole Side Effects Report #5347254-5
Letrozole side effect was reported by a Physician from BELGIUM on May 31, 2007. Female patient, 65 years of age, weighting 162.7 lb, was diagnosed with breast cancer , prophylaxis and was treated with Letrozole. After drug was administered, patient experienced the following side effects: bone disorder, gingival recession, osteonecrosis . Letrozole dosage: 2.5 MG, QD. During the same period patient was treated with ZOLEDRONIC ACID, ASPIRIN, CACIT VITAMINE D3. Patient recovered.

Letrozole Side Effects Report #5155032-5
Letrozole side effect was reported by a Physician from BELGIUM on Apr 28, 2006. Female patient, 65 years of age, weighting 162.7 lb, was diagnosed with breast cancer , prophylaxis and was treated with Letrozole. After drug was administered, patient experienced the following side effects: bone disorder, bone neoplasm, gingival disorder, osteonecrosis . Letrozole dosage: 2.5 MG, QD. During the same period patient was treated with ZOLEDRONIC ACID, ASPIRIN, CACIT VITAMINE D3. Patient recovered.


Letrozole Side Effects Report #5505463-6
Letrozole side effect was reported by a Physician from BELGIUM on Oct 25, 2007. Female patient, 65 years of age, weighting 162.7 lb, was diagnosed with breast cancer , prophylaxis and was treated with Letrozole. After drug was administered, patient experienced the following side effects: bone disorder, gingival recession, osteonecrosis . Letrozole dosage: 2.5 MG, QD. During the same period patient was treated with ZOLEDRONIC ACID, ASPIRIN, CACIT VITAMINE D3. Patient recovered.

Letrozole Side Effects Report #4996862-X
Letrozole side effect was reported by a Physician from BELGIUM on Apr 28, 2006. Female patient, 65 years of age, weighting 162.7 lb, was diagnosed with breast cancer  and was treated with Letrozole. After drug was administered, patient experienced the following side effects: bone disorder, gingival disorder, osteonecrosis . Letrozole dosage: 2.5 MG, QD. During the same period patient was treated with ZOLEDRONIC ACID. Patient recovered.

Letrozole Side Effects Report #5888848-8
Letrozole side effect was reported by a Health Professional from UNITED STATES on Sept 09, 2008. Female patient, 51 years of age, was diagnosed with breast cancer , neoplasm recurrence and was treated with Letrozole. After drug was administered, patient experienced the following side effects: actinomycosis, bone disorder, bone trimming, chest wall operation, inflammation, jaw disorder, neoplasm recurrence, osteonecrosis . Letrozole dosage: unknown. During the same period patient was treated with BEVACIZUMAB, HORMONES NOS, PACLITAXEL, CAPECITABINE. Patient recovered.

Letrozole Side Effects Report #4666112-2
Letrozole side effect was reported by a Physician from on Jan 03, 2005. Female patient, 60 years of age, was diagnosed with metastases to bone and was treated with Letrozole. After drug was administered, patient experienced the following side effects: osteonecrosis , tooth extraction. Letrozole dosage: 2.5 MG, QD. During the same period patient was treated with EXEMESTANE, CAPECITABINE, AREDIA. Patient recovered.