Leponex and agranulocytosis Patient Reports February 12, 2012

Leponex Side Effects Report #5191113-8
Leponex side effect was reported by a Consumer or non-health professional from FRANCE on Dec 19, 2006. Female patient, 35 years of age, weighting 165.3 lb, was diagnosed with schizotypal personality disorder and was treated with Leponex. After drug was administered, patient experienced the following side effects: agranulocytosis, c-reactive protein increased, neutropenia, parotitis, pyrexia, spinal myelogram abnormal, white blood cell count decreased. Leponex dosage: 300 MG, BID. During the same period patient was treated with DEPAKENE, VICTAN. Patient was hospitalized. Patient recovered.

Leponex Side Effects Report #4720814-8
Leponex side effect was reported by a Consumer or non-health professional from ITALY on July 13, 2005. Male patient, 34 years of age, was diagnosed with schizophrenia, paranoid type and was treated with Leponex. After drug was administered, patient experienced the following side effects: agranulocytosis, electroencephalogram abnormal, grand mal convulsion. Leponex dosage: unknown. During the same period patient was treated with CARBAMAZEPINE. Patient was hospitalized. Patient recovered.

Leponex Side Effects Report #4738253-2
Leponex side effect was reported by a Health Professional from FINLAND on July 28, 2005. Female patient, 59 years of age, was diagnosed with schizophrenia and was treated with Leponex. After drug was administered, patient experienced the following side effects: agranulocytosis, c-reactive protein increased, ear infection , neutrophil count decreased, oral pain, palatal oedema, sepsis , staphylococcal infection , white blood cell count decreased. Leponex dosage: unknown. During the same period patient was treated with TENOX, DIVINA, MOVICOL, DIAPAM, RISPERDAL, ORUDIS, NICORETTE. Patient was hospitalized. Patient recovered.

Leponex Side Effects Report #4885266-6
Leponex side effect was reported by a Consumer or non-health professional from FRANCE on Jan 09, 2006. Male patient, 56 years of age, was diagnosed with schizophrenia and was treated with Leponex. After drug was administered, patient experienced the following side effects: agranulocytosis, lung disorder, pyrexia. Leponex dosage: unknown. Patient was hospitalized. Patient recovered.


Leponex Side Effects Report #4903527-9
Leponex side effect was reported by a Consumer or non-health professional from FRANCE on Jan 09, 2006. Male patient, 56 years of age, was diagnosed with schizophrenia and was treated with Leponex. After drug was administered, patient experienced the following side effects: agranulocytosis, lung disorder, pyrexia. Leponex dosage: unknown. Patient was hospitalized. Patient recovered.

Leponex Side Effects Report #4698180-6
Leponex side effect was reported by a Physician from on June 17, 2005. Male patient, 39 years of age, was diagnosed with schizophrenia, bipolar disorder  and was treated with Leponex. After drug was administered, patient experienced the following side effects: agranulocytosis, leukopenia. Leponex dosage: unknown. During the same period patient was treated with TRILEPTAL. Patient was hospitalized. Patient recovered.

Leponex Side Effects Report #4625983-6
Leponex side effect was reported by a Physician from on Feb 09, 2005. Male patient, 33 years of age, was diagnosed with schizophrenia and was treated with Leponex. After drug was administered, patient experienced the following side effects: abscess , agranulocytosis, dyspnoea, leukopenia, pyrexia, sepsis . Leponex dosage: 350 MG/DAY. During the same period patient was treated with LAMICTAL, FLUANXOL. Patient was hospitalized. Patient recovered.

Leponex Side Effects Report #5957103-X
Leponex side effect was reported by a Physician from PHILIPPINES on Nov 14, 2008. Male patient, 27 years of age, was diagnosed with schizophrenia and was treated with Leponex. After drug was administered, patient experienced the following side effects: agranulocytosis, cough, eosinophil count decreased, lymphocyte count decreased, nasopharyngitis, neutrophil count decreased, pyrexia, white blood cell count decreased. Leponex dosage: 25 MG / DAY. During the same period patient was treated with SERENACE, ADALAT, OLANZAPINE. Patient was hospitalized. Patient recovered.

Leponex Side Effects Report #4841252-3
Leponex side effect was reported by a Physician from YUGOSLAVIA on Nov 25, 2005. Male patient, 21 years of age, weighting 176.4 lb, was diagnosed with schizophrenia and was treated with Leponex. After drug was administered, patient experienced the following side effects: agranulocytosis, aphthous stomatitis, oral mucosal disorder, pyrexia. Leponex dosage: 100 MG/DAY. Patient was hospitalized. Patient recovered.


Leponex Side Effects Report #6097041-8
Leponex side effect was reported by a Health Professional from CZECH REPUBLIC on Feb 24, 2009. Male patient was diagnosed with schizophrenia and was treated with Leponex. After drug was administered, patient experienced the following side effects: agranulocytosis, bone marrow failure, febrile neutropenia, multi-organ failure, sepsis . Leponex dosage: 25 MG, 1 TABLET, 1/2 TABLET FOLLOWED BY 1 TABLET. During the same period patient was treated with AKINETON, PARALEN, DOXYBENE, AXETIN, MAXIPIME, MYCOMAX, CIPRINOL, IBALGIN. Patient was hospitalized. Patient died.

Leponex Side Effects Report #5970995-3
Leponex side effect was reported by a Physician from GERMANY on Nov 24, 2008. Female patient, 50 years of age, was diagnosed with schizoaffective disorder and was treated with Leponex. After drug was administered, patient experienced the following side effects: agranulocytosis, femur fracture, joint dislocation, leukopenia, lower limb fracture, moyamoya disease, neutrophil count decreased, white blood cell count decreased. Leponex dosage: 200 MG DAILY. During the same period patient was treated with ASPIRIN. Patient was hospitalized. Patient recovered.

Leponex Side Effects Report #5168669-4
Leponex side effect was reported by a Physician from GERMANY on Dec 08, 2006. Female patient, 65 years of age, weighting 207.2 lb, was diagnosed with psychotic disorder  and was treated with Leponex. After drug was administered, patient experienced the following side effects: agranulocytosis, intubation, leukopenia, life support, pyrexia, sepsis . Leponex dosage: UP TO 300 MG/DAY. Patient was hospitalized. Patient recovered.

Leponex Side Effects Report #4752367-2
Leponex side effect was reported by a Physician from FINLAND on Aug 23, 2005. Female patient, 58 years of age, was diagnosed with psychotic disorder  and was treated with Leponex. After drug was administered, patient experienced the following side effects: abscess , acquired cardiac septal defect, agranulocytosis, blood creatinine increased, c-reactive protein increased, diarrhoea, hypokalaemia, nephropathy toxic, neutrophil count decreased. Leponex dosage: 400 MG/D. During the same period patient was treated with LAMICTAL, SCOPODERM, CIPRAMIL. Patient was hospitalized. Patient recovered.

Leponex Side Effects Report #4896661-3
Leponex side effect was reported by a Consumer or non-health professional from HUNGARY on Jan 27, 2006. Female patient, 53 years of age, weighting 132.3 lb, was diagnosed with psychotic disorder  and was treated with Leponex. After drug was administered, patient experienced the following side effects: agranulocytosis, pyrexia, respiratory failure, sepsis . Leponex dosage: unknown. Patient died on 01/12/2006.


Leponex Side Effects Report #4563621-1
Leponex side effect was reported by a Physician from on Jan 24, 2005. Female patient, 49 years of age, was diagnosed with psychotic disorder , anxiety , depression  and was treated with Leponex. After drug was administered, patient experienced the following side effects: agranulocytosis, leukopenia, peritonitis, surgery , ulcer , wound infection. Leponex dosage: unknown. During the same period patient was treated with LORAZEPAM, CIPRAMIL. Patient was hospitalized. Patient recovered.

Leponex Side Effects Report #4860898-X
Leponex side effect was reported by a Consumer or non-health professional from FRANCE on Dec 13, 2005. Male patient, 82 years of age, was diagnosed with paraphilia and was treated with Leponex. After drug was administered, patient experienced the following side effects: agranulocytosis, confusional state, leukopenia, myeloid maturation arrest, neutrophil count decreased, psychomotor retardation, pyrexia. Leponex dosage: 12.5 MG, QD. During the same period patient was treated with LEVODOPA, VALSARTAN, ATENOLOL, PAROXETINE, ACARBOSE, CLOPIDOGREL, OMEPRAZOLE, LORMETAZEPAM. Patient was hospitalized. Patient recovered.

Leponex Side Effects Report #5520675-3
Leponex side effect was reported by a Physician from BELGIUM on Nov 12, 2007. Female patient, 75 years of age, was treated with Leponex. After drug was administered, patient experienced the following side effects: acute febrile neutrophilic dermatosis, agranulocytosis, body temperature increased, circulatory collapse, eosinophilia, leukocytosis, leukopenia, neutropenia, rash erythematous. Leponex dosage: 150 MG/DAY. During the same period patient was treated with SEROQUEL, TENORMIN. Patient was hospitalized. Patient died.

Leponex Side Effects Report #5524776-5
Leponex side effect was reported by a Physician from BELGIUM on Nov 22, 2007. Female patient, 75 years of age, was treated with Leponex. After drug was administered, patient experienced the following side effects: acute febrile neutrophilic dermatosis, agranulocytosis, body temperature increased, circulatory collapse, eosinophilia, leukocytosis, leukopenia, neutropenia, rash erythematous. Leponex dosage: 150 MG/DAY. During the same period patient was treated with SEROQUEL, TENORMIN. Patient was hospitalized. Patient died on 10/09/2005.

Leponex Side Effects Report #5958005-5
Leponex side effect was reported by a Physician from GERMANY on Nov 10, 2008. Female patient, 50 years of age, was treated with Leponex. After drug was administered, patient experienced the following side effects: agranulocytosis, femur fracture, neutrophil count decreased, white blood cell count decreased. Leponex dosage: 100 MG, BID. During the same period patient was treated with ASPIRIN. Patient was hospitalized. Patient recovered.


Leponex Side Effects Report #4544543-9
Leponex side effect was reported by a Health Professional from on Nov 30, 2004. Female patient, 44 years of age, was treated with Leponex. After drug was administered, patient experienced the following side effects: agranulocytosis, c-reactive protein increased, fungal skin infection, localised oedema, lymphadenopathy, neutropenia, platelet count increased, pyrexia, urosepsis. Leponex dosage: unknown. During the same period patient was treated with NOVOMIX, LAXOBERON, LEVOLAC. Patient was hospitalized. Patient recovered.

Leponex Side Effects Report #5156112-0
Leponex side effect was reported by a Physician from GREECE on Nov 21, 2006. Male patient, 40 years of age, was diagnosed with hepatitis c  and was treated with Leponex. After drug was administered, patient experienced the following side effects: agranulocytosis, hepatitis c . Leponex dosage: unknown. During the same period patient was treated with INTERFERON. Patient recovered.

Leponex Side Effects Report #5382875-5
Leponex side effect was reported by a Physician from GERMANY on June 29, 2007. Male patient, 29 years of age, weighting 165.3 lb, was treated with Leponex. After drug was administered, patient experienced the following side effects: agranulocytosis, neutrophil count decreased, staphylococcal sepsis, white blood cell count decreased. Leponex dosage: 500 MG/DAY. Patient was hospitalized. Patient recovered.

Leponex Side Effects Report #5892730-X
Leponex side effect was reported by a Health Professional from SWITZERLAND on Sept 19, 2008. Male patient was treated with Leponex. After drug was administered, patient experienced the following side effects: agranulocytosis, hepatitis c , leukopenia, suicide attempt. Leponex dosage: 500 MG/DAY. During the same period patient was treated with COPEGUS, PEGASYS, REMERON, HALDOL, TEMESTA, AKINETON, ZYPREXA, NEXIUM. Patient was hospitalized. Patient recovered.