Lepirudin and activated partial thromboplastin time prolonged Patient Reports February 12, 2012

Lepirudin Side Effects Report #5015387-9
Lepirudin side effect was reported by a Pharmacist from UNITED STATES on May 30, 2006. Female patient, 88 years of age, was diagnosed with thrombosis and was treated with Lepirudin. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, catheter site haemorrhage, confusional state, epistaxis, international normalised ratio increased, mouth haemorrhage. Lepirudin dosage: 0.15MG/KG/HR. Patient recovered.

Lepirudin Side Effects Report #5206911-1
Lepirudin side effect was reported by a Consumer or non-health professional from UNITED STATES on Jan 05, 2007. Female patient, 84 years of age, was diagnosed with deep vein thrombosis , pulmonary embolism  and was treated with Lepirudin. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, blood creatinine increased, creatinine renal clearance decreased, haemoglobin decreased. Lepirudin dosage: unknown. During the same period patient was treated with AMIODARONE, FUROSEMIDE, FENTANYL TRANSDERMAL SYSTEM, AZTREONAM, HYDRALAZINE, METOPROLOL SUCCINATE, RANITIDINE. Patient was hospitalized. Patient recovered.

Lepirudin Side Effects Report #4748530-7
Lepirudin side effect was reported by a Pharmacist from UNITED STATES on Aug 18, 2005. Male patient, 64 years of age, weighting 165.3 lb, was diagnosed with deep vein thrombosis , heparin-induced thrombocytopenia and was treated with Lepirudin. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, oesophageal haemorrhage. Lepirudin dosage: unknown. Patient was hospitalized. Patient recovered.

Lepirudin Side Effects Report #5144260-0
Lepirudin side effect was reported by a Pharmacist from UNITED STATES on Nov 02, 2006. Female patient, 57 years of age, weighting 194.0 lb, was treated with Lepirudin. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, cardio-respiratory arrest, catheter site haemorrhage, infusion related reaction, ventricular fibrillation. Lepirudin dosage: 0.2 MG/KG -17.6 MG TOTAL NOW IV BOLUS. Patient recovered.


Lepirudin Side Effects Report #5426099-1
Lepirudin side effect was reported by a Pharmacist from UNITED STATES on Aug 23, 2007. Female patient, 26 years of age, was treated with Lepirudin. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, catheter site haemorrhage, condition aggravated, haemoptysis. Lepirudin dosage: unknown. Patient recovered.