Isovorin and diarrhoea Patient Reports February 12, 2012

Isovorin Side Effects Report #5558100-9
Isovorin side effect was reported by a Physician from JAPAN on Dec 06, 2007. Female patient, 82 years of age, was diagnosed with large intestine carcinoma and was treated with Isovorin. After drug was administered, patient experienced the following side effects: diarrhoea, leukopenia, vomiting. Isovorin dosage: unknown. During the same period patient was treated with ELPLAT, FLUOROURACIL. Patient died on 11/29/2007.

Isovorin Side Effects Report #5573192-9
Isovorin side effect was reported by a Physician from JAPAN on Dec 13, 2007. Female patient, 82 years of age, weighting 94.80 lb, was diagnosed with rectal cancer and was treated with Isovorin. After drug was administered, patient experienced the following side effects: diarrhoea, leukopenia, stevens-johnson syndrome, vomiting. Isovorin dosage: 125 MG/BODY=92.6 MG/M2. During the same period patient was treated with ELPLAT, FLUOROURACIL. Patient died on 11/29/2007.

Isovorin Side Effects Report #5080440-0
Isovorin side effect was reported by a Health Professional from JAPAN on July 26, 2006. Male patient, 60 years of age, weighting 112.4 lb, was diagnosed with rectal cancer and was treated with Isovorin. After drug was administered, patient experienced the following side effects: bradycardia, cardiac arrest , depressed level of consciousness, diarrhoea, disseminated intravascular coagulation, leukopenia, metabolic acidosis, neutropenia. Isovorin dosage: unknown. During the same period patient was treated with OXALIPLATIN, FLUOROURACIL. Patient died on 07/26/2006.

Isovorin Side Effects Report #5810595-9
Isovorin side effect was reported by a Physician from JAPAN on July 07, 2008. Male patient was diagnosed with colon cancer metastatic and was treated with Isovorin. After drug was administered, patient experienced the following side effects: diarrhoea, palmar-plantar erythrodysaesthesia syndrome, stomatitis, white blood cell count decreased. Isovorin dosage: unknown. During the same period patient was treated with FLUOROURACIL, ELPLAT, AVASTIN. Patient recovered.


Isovorin Side Effects Report #5922426-7
Isovorin side effect was reported by a Physician from JAPAN on Oct 09, 2008. Male patient was diagnosed with colon cancer metastatic and was treated with Isovorin. After drug was administered, patient experienced the following side effects: diarrhoea, palmar-plantar erythrodysaesthesia syndrome, stomatitis, white blood cell count decreased. Isovorin dosage: unknown. During the same period patient was treated with FLUOROURACIL, ELPLAT, AVASTIN. Patient recovered.