Isoniazid and hepatic failure Patient Reports February 12, 2012

Isoniazid Side Effects Report #5166013-X
Isoniazid side effect was reported by a Physician from UNITED STATES on Nov 13, 2006. Female patient, 39 years of age, was diagnosed with tuberculosis skin test positive and was treated with Isoniazid. After drug was administered, patient experienced the following side effects: asthenia, brain herniation, coagulopathy, hepatic encephalopathy, hepatic failure, liver transplant , procedural complication, renal failure. Isoniazid dosage: unknown. Patient was hospitalized. Patient died.

Isoniazid Side Effects Report #5090811-4
Isoniazid side effect was reported by a Consumer or non-health professional from SPAIN on Aug 15, 2006. Male patient, 39 years of age, was diagnosed with tuberculosis  and was treated with Isoniazid. After drug was administered, patient experienced the following side effects: ascites, coagulopathy, cytolytic hepatitis, hepatic atrophy, hepatic encephalopathy, hepatic failure, liver transplant , pyrexia, rash . Isoniazid dosage: 300 MG DAILY,. During the same period patient was treated with PYRAZINAMIDE, RIFAMPICIN, VANCOMYCIN, CEFTAZIDIME, ETHAMBUTOL, LEVOFLOXACIN, STREPTOMYCIN, CIPROFLOXACIN. Patient was hospitalized. Patient recovered.

Isoniazid Side Effects Report #4593971-4
Isoniazid side effect was reported by a Physician from on Feb 15, 2005. Female patient, 16 years of age, was diagnosed with tuberculosis , epilepsy  and was treated with Isoniazid. After drug was administered, patient experienced the following side effects: hepatic failure, tremor. Isoniazid dosage: 250 MG/DAY. During the same period patient was treated with CARBAMAZEPINE, RIFAMPICIN, PYRAZINAMIDE, CLOBAZAM. Patient was hospitalized. Patient recovered.

Isoniazid Side Effects Report #4597028-8
Isoniazid side effect was reported by a Consumer or non-health professional from on Feb 15, 2005. Female patient, 16 years of age, was diagnosed with tuberculosis , epilepsy  and was treated with Isoniazid. After drug was administered, patient experienced the following side effects: asterixis, depressed level of consciousness, encephalopathy, hepatic failure, jaundice , prothrombin time prolonged, somnolence. Isoniazid dosage: 250 MG/DAY. During the same period patient was treated with CARBAMAZEPINE, RIFAMPICIN, PYRAZINAMIDE, CLOBAZAM. Patient was hospitalized. Patient recovered.


Isoniazid Side Effects Report #5006297-1
Isoniazid side effect was reported by a Consumer or non-health professional from UNITED STATES on May 17, 2006. Male patient, 29 years of age, weighting 160.0 lb, was diagnosed with tuberculin test positive and was treated with Isoniazid. After drug was administered, patient experienced the following side effects: dehydration, dementia , hepatic failure. Isoniazid dosage: unknown. During the same period patient was treated with VITAMIN B6. Patient died on 03/03/2006.

Isoniazid Side Effects Report #4701354-9
Isoniazid side effect was reported by a Consumer or non-health professional from on June 14, 2005. Male patient, child 10 years of age, weighting 59.52 lb, was diagnosed with tuberculin test positive and was treated with Isoniazid. After drug was administered, patient experienced the following side effects: duodenal ulcer, duodenal ulcer haemorrhage, encephalopathy, graft dysfunction, graft thrombosis, hepatic failure, lethargy, liver transplant . Isoniazid dosage: 300 MG, ORAL. Patient was hospitalized. Patient recovered.

Isoniazid Side Effects Report #4701740-7
Isoniazid side effect was reported by a Physician from on June 14, 2005. Female patient, 46 years of age, was diagnosed with pleurisy and was treated with Isoniazid. After drug was administered, patient experienced the following side effects: ascites, condition aggravated, convulsion, hepatic atrophy, hepatic encephalopathy, hepatic failure, hypoglycaemia, loss of consciousness. Isoniazid dosage: unknown. During the same period patient was treated with PYRAZINAMIDE, RIFAMPICIN. Patient was hospitalized. Patient died.

Isoniazid Side Effects Report #6122022-5
Isoniazid side effect was reported by a Consumer or non-health professional from UNITED STATES on Mar 09, 2009. Female patient, 67 years of age, was diagnosed with antibiotic prophylaxis and was treated with Isoniazid. After drug was administered, patient experienced the following side effects: hepatic failure, neck pain, nervous system disorder, pyrexia. Isoniazid dosage: unknown. Patient was hospitalized. Patient recovered.