Irinotecan and thrombocytopenia Patient Reports February 12, 2012

Irinotecan Side Effects Report #5265319-3
Irinotecan side effect was reported by a Consumer or non-health professional from SPAIN on Mar 05, 2007. Male patient, weighting 90.39 lb, was diagnosed with rhabdomyosarcoma and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: ascites, chronic hepatitis, enterocolitis, neutropenia, oedema, thrombocytopenia. Irinotecan dosage: unknown. During the same period patient was treated with CARBOPLATIN, ONDANSETRON, LOPERAMIDE, MORPHINE, COTRIM, OMEPRAZOLE, METOCLOPRAMIDE. Patient was hospitalized and became disabled. Patient recovered.

Irinotecan Side Effects Report #5154626-0
Irinotecan side effect was reported by a Physician from GERMANY on Mar 28, 1998. Male patient, 67 years of age, was diagnosed with rectal cancer metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: atrial fibrillation , leukopenia, malignant neoplasm progression, rectal cancer metastatic, sepsis , thrombocytopenia. Irinotecan dosage: 530 MG, INTRAVENOUS. During the same period patient was treated with ALLOPURINOL, DEXABENE, ZANTIC, ZOFRAN. Patient died on 03/25/1998.

Irinotecan Side Effects Report #4549585-5
Irinotecan side effect was reported by a Physician from on Dec 28, 2004. Male patient, 62 years of age, was diagnosed with rectal cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: haematuria, infusion related reaction, thrombocytopenia. Irinotecan dosage: unknown. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5375368-2
Irinotecan side effect was reported by a Health Professional from JAPAN on June 18, 2007. Male patient, weighting 132.3 lb, was diagnosed with rectal cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, interstitial lung disease, thrombocytopenia. Irinotecan dosage: DAILY DOSE:120MG. During the same period patient was treated with TEGAFUR, LOXOPROFEN, GABEXATE MESILATE. Patient was hospitalized. Patient died.


Irinotecan Side Effects Report #5117075-7
Irinotecan side effect was reported by a Health Professional from JAPAN on Sept 11, 2006. Female patient, 71 years of age, was diagnosed with ovarian cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: cellulitis , marrow hyperplasia, myelodysplastic syndrome, rectal neoplasm, refractory anaemia with an excess of blasts, thrombocytopenia, vaginal haemorrhage. Irinotecan dosage: unknown. Patient recovered.

Irinotecan Side Effects Report #5241869-0
Irinotecan side effect was reported by a Physician from JAPAN on Feb 08, 2007. Male patient, 72 years of age, was diagnosed with neoplasm of thymus and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: anaemia, disseminated intravascular coagulation, multi-organ failure, thrombocytopenia. Irinotecan dosage: unknown. During the same period patient was treated with KYTRIL, DECADRON, FESIN, PRIMPERAN. Patient was hospitalized. Patient died on 02/05/2007.

Irinotecan Side Effects Report #5256770-6
Irinotecan side effect was reported by a Physician from JAPAN on Feb 22, 2007. Male patient, 72 years of age, was diagnosed with neoplasm of thymus and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: anaemia, disseminated intravascular coagulation, multi-organ failure, thrombocytopenia. Irinotecan dosage: unknown. During the same period patient was treated with KYTRIL, DECADRON, FESIN, PRIMPERAN, LACTEC. Patient was hospitalized. Patient died on 02/05/2007.

Irinotecan Side Effects Report #5321374-3
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on May 07, 2007. Female patient, weighting 105.8 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: confusional state, hyperglycaemia, hyponatraemia, leukopenia, neutrophil count decreased, platelet count decreased, thrombocytopenia. Irinotecan dosage: 125MG/M2 DAY 1, 8, 22, 29 IV. During the same period patient was treated with TEMODAR, NEXIUM, PREMARIN, ALLEGRA, LOTREL. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5323958-5
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on May 09, 2007. Female patient, weighting 105.8 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: confusional state, hyperglycaemia, hyponatraemia, leukopenia, thrombocytopenia, white blood cell count decreased. Irinotecan dosage: 125MG/M2 DAY 1, 8, 22, 29 IV. During the same period patient was treated with TEMODAR, NEXIUM, PREMARIN, ALLEGRA, LOTREL. Patient was hospitalized. Patient recovered.


Irinotecan Side Effects Report #5418667-8
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 08, 2007. Male patient, weighting 218.3 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: arrhythmia supraventricular, diarrhoea, hyperglycaemia, neutropenia, renal failure, thrombocytopenia. Irinotecan dosage: DAILY DOSE:125MG/M2-FREQ:FREQUENCY: ON DAY 1, 8, 22, 29. During the same period patient was treated with TEMODAR, WARFARIN, LOTREL, LASIX, TOPROL, DECADRON, LIPITOR. Patient was hospitalized. Patient died on 08/02/2007.

Irinotecan Side Effects Report #5427489-3
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 24, 2007. Female patient, weighting 105.8 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: confusional state, hyperglycaemia, hyponatraemia, leukopenia, neutropenia, thrombocytopenia. Irinotecan dosage: 125MG/M2 DAY 1, 8, 22, 29. During the same period patient was treated with TEMODAR, NEXIUM, PREMARIN, ALLEGRA, LOTREL. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5657376-7
Irinotecan side effect was reported by a Health Professional from JAPAN on Feb 27, 2008. Female patient, 73 years of age, weighting 116.8 lb, was diagnosed with gastric cancer, nutritional support  and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: altered state of consciousness, diarrhoea, leukopenia, neutropenia, thrombocytopenia. Irinotecan dosage: unknown. During the same period patient was treated with CISPLATIN, DECADRON, NASEA, PRIMPERAN, FULCALIQ. Patient was hospitalized. Patient died on 06/18/2007.

Irinotecan Side Effects Report #4615976-7
Irinotecan side effect was reported by a Physician from on Mar 08, 2005. Male patient, 67 years of age, was diagnosed with gastric cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: hyponatraemia, leukopenia, neutropenia, thrombocytopenia. Irinotecan dosage: 110 + 90 MG, INTRAVENOUS. During the same period patient was treated with CISPLATIN. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #4642357-2
Irinotecan side effect was reported by a Physician from on Apr 07, 2005. Male patient, 67 years of age, was diagnosed with gastric cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: hyponatraemia, leukopenia, neutropenia, thrombocytopenia. Irinotecan dosage: unknown. During the same period patient was treated with CISPLATIN. Patient was hospitalized. Patient recovered.


Irinotecan Side Effects Report #5588617-2
Irinotecan side effect was reported by a Consumer or non-health professional from JAPAN on Jan 02, 2008. Male patient, weighting 121.3 lb, was diagnosed with gastric cancer, polyuria, prophylaxis of nausea and vomiting and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, leukopenia, neutropenia, septic shock, thrombocytopenia. Irinotecan dosage: unknown. During the same period patient was treated with RANDA, LASIX, DECADRON, KYTRIL. Patient recovered.

Irinotecan Side Effects Report #5592380-9
Irinotecan side effect was reported by a Consumer or non-health professional from JAPAN on Jan 09, 2008. Male patient, weighting 121.3 lb, was diagnosed with gastric cancer, polyuria, prophylaxis of nausea and vomiting and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, leukopenia, neutropenia, septic shock, thrombocytopenia. Irinotecan dosage: unknown. During the same period patient was treated with RANDA, LASIX, DECADRON, KYTRIL. Patient recovered.

Irinotecan Side Effects Report #5664870-1
Irinotecan side effect was reported by a Health Professional from JAPAN on Mar 04, 2008. Female patient, weighting 116.8 lb, was diagnosed with gastric cancer, brain oedema, nutritional support  and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: altered state of consciousness, anorexia, diarrhoea, dysphagia, leukopenia, nausea , neutropenia, thrombocytopenia. Irinotecan dosage: DAILY DOSE:100MG. During the same period patient was treated with CISPLATIN, DECADRON, NASEA, PRIMPERAN, FULCALIQ. Patient was hospitalized. Patient died on 06/18/2007.

Irinotecan Side Effects Report #4893364-6
Irinotecan side effect was reported by a Health Professional from UNITED STATES on Jan 25, 2006. Female patient, weighting 116.0 lb, was diagnosed with gastric cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: deep vein thrombosis , neutropenia, thrombocytopenia. Irinotecan dosage: 75 MG IV , D1 + D8 Q 3 WKS. During the same period patient was treated with CISPLATIN, AMBIEN, PREVACID, PROCRIT, MYCELEX. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #4918148-1
Irinotecan side effect was reported by a Physician from JAPAN on Jan 31, 2006. Male patient, 75 years of age, weighting 103.6 lb, was diagnosed with colorectal cancer  and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: candidiasis, diarrhoea, haemoglobin decreased, interstitial lung disease, leukopenia, neutropenia, thrombocytopenia. Irinotecan dosage: 180 MG, INTRAVENOUS. During the same period patient was treated with FLUOROURACIL, CALCIUM LEVOFOLINATE, RED BLOOD CELLS. Patient was hospitalized. Patient recovered.


Irinotecan Side Effects Report #4675299-7
Irinotecan side effect was reported by a Health Professional from on May 12, 2005. Male patient, 71 years of age, was diagnosed with colorectal cancer  and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: haemoglobin decreased, interstitial lung disease, malignant pleural effusion, thrombocytopenia. Irinotecan dosage: unknown. During the same period patient was treated with FURTULON, COLONEL, HERBAL PREPARATION, ZOLPIDEM TARTRATE, MAGNESIUM OXIDE. Patient died on 02/18/2005.

Irinotecan Side Effects Report #5831411-5
Irinotecan side effect was reported by a Consumer or non-health professional from SOUTH AFRICA on July 24, 2008. Female patient, weighting 72.75 lb, was diagnosed with colorectal cancer , hypertension, gastritis, diarrhoea and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: dehydration, gastroenteritis , haematemesis, haemoptysis, neutropenia, oesophageal candidiasis, oral candidiasis, thrombocytopenia. Irinotecan dosage: unknown. During the same period patient was treated with FLUOROURACIL, LEUCOVORIN CALCIUM, HYDROCHLOROTHIAZIDE, PERINDOPRIL ERBUMINE, OMEPRAZOLE, LOPERAMIDE. Patient was hospitalized. Patient died on 07/03/2008.

Irinotecan Side Effects Report #5465540-5
Irinotecan side effect was reported by a Consumer or non-health professional from GERMANY on Aug 20, 1997. Male patient was diagnosed with colon cancer metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: abdominal pain , blood bilirubin increased, c-reactive protein increased, diarrhoea, neutropenia, thrombocytopenia. Irinotecan dosage: DAILY DOSE:350MG/M2-FREQ:EVERY 3 WEEKS. During the same period patient was treated with ECHINACIN. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5642610-X
Irinotecan side effect was reported by a Pharmacist from UNITED STATES on Feb 27, 2008. Male patient, weighting 170.0 lb, was diagnosed with colon cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: abdominal pain , asthenia, dehydration, diarrhoea, neutropenia, thrombocytopenia, white blood cell count decreased. Irinotecan dosage: unknown. During the same period patient was treated with DIOVAN, CARDIZEM CD, AMBIEN. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #4548191-6
Irinotecan side effect was reported by a Pharmacist from on Jan 05, 2005. Male patient, 80 years of age, weighting 130.1 lb, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: anaemia, diarrhoea, electrolyte imbalance, hypovolaemia, neutropenia, rectal haemorrhage, thrombocytopenia. Irinotecan dosage: unknown. During the same period patient was treated with CISPLATIN. Patient was hospitalized. Patient died on 11/03/2004.


Irinotecan Side Effects Report #5375662-5
Irinotecan side effect was reported by a Health Professional from JAPAN on June 21, 2007. Male patient, 75 years of age, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: leukopenia, pulmonary haemorrhage, thrombocytopenia. Irinotecan dosage: unknown. During the same period patient was treated with PARAPLATIN, ALDACTONE, PURSENNID, FIRSTCIN. Patient died on 06/18/2007.

Irinotecan Side Effects Report #4880334-7
Irinotecan side effect was reported by a Physician from UNITED STATES on Dec 30, 2005. Male patient, 71 years of age, weighting 176.4 lb, was diagnosed with ill-defined disorder and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: anaemia, dyspnoea, fatigue, febrile neutropenia, hypomagnesaemia, pneumonia , thrombocytopenia. Irinotecan dosage: 100 MG/M2 (CYCLICAL), INTRAVENOUS. During the same period patient was treated with NEUPOGEN, VITAMIN, VITAMIN C, VITAMIN B12, PRIMATENE MIST, ALEVE, EXCEDRIN, DECADRON. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #4954749-2
Irinotecan side effect was reported by a Physician from FRANCE on Jan 09, 2006. Male patient, 56 years of age, weighting 165.3 lb, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: acute respiratory failure, bone marrow failure, neutropenia, oxygen saturation decreased, sepsis , thrombocytopenia. Irinotecan dosage: 123 MG (123 MG, 1 IN 1 D), INTRAVENOUS. During the same period patient was treated with CISPLATIN, PRIMPERAN, LEXOMIL, DURAGESIC, LASIX, VOGALENE, ATROPINE. Patient was hospitalized. Patient died on 12/20/2005.

Irinotecan Side Effects Report #4984300-2
Irinotecan side effect was reported by a Physician from FRANCE on Apr 03, 2006. Male patient, 56 years of age, weighting 165.3 lb, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: acute respiratory failure, bone marrow failure, neutropenia, thrombocytopenia. Irinotecan dosage: 123 MG (123 MG, 1 IN 1 D), INTRAVENOUS. During the same period patient was treated with CISPLATIN, PRIMPERAN, LEXOMIL, DURAGESIC, LASIX, VOGALENE, ATROPINE. Patient was hospitalized. Patient died on 12/20/2005.

Irinotecan Side Effects Report #4561311-2
Irinotecan side effect was reported by a Physician from on Dec 14, 2004. Male patient, 53 years of age, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: anaemia, dysphagia, febrile neutropenia, headache , pyrexia, radiation oesophagitis, thrombocytopenia. Irinotecan dosage: 100 MG/M2 (WEEKLY), INTRAVENOUS. During the same period patient was treated with TOPOSAR, CISPLATIN, FENTANYL, MORPHINE SULPHATE, STOMATOLOGICALS, CIPROFLOXACIN, OMEPRAZOLE. Patient was hospitalized. Patient recovered.


Irinotecan Side Effects Report #5692096-4
Irinotecan side effect was reported by a Consumer or non-health professional from FRANCE on Mar 25, 2008. Male patient, weighting 165.3 lb, was diagnosed with nausea , anxiety , pain , polyuria, diarrhoea and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: acute respiratory failure, neutropenia, thrombocytopenia. Irinotecan dosage: unknown. During the same period patient was treated with CISPLATIN, PRIMPERAN, LEXOMIL, DURAGESIC, LASILIX, VOGALENE, ATROPINE. Patient was hospitalized. Patient died on 12/20/2005.

Irinotecan Side Effects Report #5919827-X
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Oct 06, 2008. Male patient, weighting 172.0 lb, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: cardiac failure congestive, hyponatraemia, leukopenia, neutropenic sepsis, thrombocytopenia. Irinotecan dosage: unknown. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient died on 10/06/2008.

Irinotecan Side Effects Report #5950909-2
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Nov 03, 2008. Male patient, weighting 172.0 lb, was diagnosed with nausea , anxiety , pain  and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: cardiac failure congestive, hyponatraemia, leukopenia, neutropenic sepsis, thrombocytopenia. Irinotecan dosage: unknown. During the same period patient was treated with CARBOPLATIN, COMPAZINE, PAXIL, MUCINEX, KLONOPIN, DARVOCET, PROMETHAZINE. Patient was hospitalized. Patient died on 10/06/2008.

Irinotecan Side Effects Report #6133798-5
Irinotecan side effect was reported by a Health Professional from UNITED STATES on Mar 13, 2009. Male patient, weighting 172.0 lb, was diagnosed with nausea , anxiety , pain  and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: cardiac failure congestive, hyponatraemia, leukopenia, neutropenic sepsis, thrombocytopenia. Irinotecan dosage: 60 MG/M2 (115 MG), DAYS 1, 8, 15. During the same period patient was treated with CARBOPLATIN, COMPAZINE, PAXIL, MUCINEX, KLONOPIN, DARVOCET, PROMETHAZINE. Patient was hospitalized. Patient died on 10/06/2008.