Irinotecan and pulmonary embolism Patient Reports February 12, 2012

Irinotecan Side Effects Report #5506288-8
Irinotecan side effect was reported by a Health Professional from UNITED STATES on Nov 01, 2007. Male patient, weighting 150.8 lb, was diagnosed with metastatic carcinoma of the bladder and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: catheter site related reaction, haemoptysis, ileus paralytic, metastases to meninges, neoplasm, pulmonary embolism . Irinotecan dosage: unknown. During the same period patient was treated with DILAUDID, DURAGESIC, COMPAZINE, REGLAN, TINAZAPARIN, LOVENOX, VICODIN. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5150732-5
Irinotecan side effect was reported by a Consumer or non-health professional from FRANCE on Feb 04, 1998. Male patient, 44 years of age, was diagnosed with metastasis, colorectal cancer  and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: abdominal pain , asthenia, malaise, pain in jaw, pulmonary embolism . Irinotecan dosage: unknown. During the same period patient was treated with FLUOROURACIL, FOLINIC ACID. Patient died on 01/19/1998.

Irinotecan Side Effects Report #4492385-5
Irinotecan side effect was reported by a Health Professional from on Nov 02, 2004. Female patient was diagnosed with metastases to central nervous system, non-small cell lung cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: oedema peripheral, pain in extremity, pulmonary embolism . Irinotecan dosage: 350 MG /M2 EVERY 3 WK. During the same period patient was treated with AMBIEN, LOVENOX, ZOLOFT, COMPAZINE, BACTRIM DS, COMBIVENT, GLUCOTROL. Patient recovered.

Irinotecan Side Effects Report #5409600-3
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 07, 2007. Male patient, weighting 153.4 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: confusional state, deep vein thrombosis , neutropenia, pulmonary embolism , pyrexia, sepsis , vomiting. Irinotecan dosage: 125MG/M2 DAY 1, 8, 22, 29 IV. During the same period patient was treated with TEMODAR, VERAPAMIL, ASPIRIN, DEXAMETHASONE, DEPAKOTE, KLONOPIN. Patient was hospitalized. Patient recovered.


Irinotecan Side Effects Report #5413433-1
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 10, 2007. Male patient, weighting 153.4 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: confusional state, deep vein thrombosis , neutropenic sepsis, pulmonary embolism , vomiting. Irinotecan dosage: 125MG/M2 DAY 1,8,22,29 IV. During the same period patient was treated with TEMODAR, VERAPAMIL, ASPIRIN, DEXAMETHASONE, DEPAKOTE, KLONOPIN. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5449769-8
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Sept 10, 2007. Male patient, weighting 153.4 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: band neutrophil count increased, colitis, constipation , febrile neutropenia, gastrointestinal disorder, haemoglobin decreased, hypotension, pulmonary embolism , sepsis . Irinotecan dosage: 125MG/M2 DAY 1, 8, 22, 29 IV. During the same period patient was treated with TEMODAR, VERAPAMIL, ASPIRIN, DEXAMETHASONE, DEPAKOTE, KLONOPIN. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #4649477-7
Irinotecan side effect was reported by a Consumer or non-health professional from on Apr 28, 2005. Male patient, weighting 189.6 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: pulmonary embolism . Irinotecan dosage: 254 MG. During the same period patient was treated with BECACIZUMAB. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #4801640-8
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Oct 14, 2005. Female patient, weighting 242.5 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: pulmonary embolism . Irinotecan dosage: 275 MG. During the same period patient was treated with BEVACIZUMAB. Patient died on 07/26/2005.

Irinotecan Side Effects Report #4835464-2
Irinotecan side effect was reported by a Health Professional from UNITED STATES on Nov 22, 2005. Female patient, weighting 166.2 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: pulmonary embolism . Irinotecan dosage: 650MG IV (DAY 1, 8,22 AND 29). During the same period patient was treated with BEVACIZUMAB, DILANTIN, DECADRON, ZANTAC, POTASSIUM. Patient was hospitalized. Patient recovered.


Irinotecan Side Effects Report #4906126-8
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Feb 07, 2006. Female patient, weighting 185.9 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: body temperature increased, pneumonia , pulmonary embolism . Irinotecan dosage: 362 MG. During the same period patient was treated with TEMOZOLOMIDE, DEXAMETHASONE, DIFLUCAN, KEPPRA, SYNTHROID, TOPROL, ZOFRAN. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #4910736-1
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Feb 09, 2006. Female patient, weighting 185.9 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: body temperature increased, pulmonary embolism . Irinotecan dosage: 362 MG. During the same period patient was treated with CAMPTOSAR, DEXAMETHASONE PHOSPHATE, DIFLUCAN, KEPPRA, SYNTHROID, TOPROL, ZOFRAN, COUMADIN. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5750256-8
Irinotecan side effect was reported by a Consumer or non-health professional from FRANCE on May 20, 2008. Male patient, weighting 167.6 lb, was diagnosed with gastric cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: atrial fibrillation , cerebrovascular accident, pulmonary embolism . Irinotecan dosage: DAILY DOSE:180MG/M2. During the same period patient was treated with FLUOROURACIL, CALCIUM FOLINATE, ATROPINE SULPHATE, ZOPHREN. Patient was hospitalized and became disabled. Patient recovered.

Irinotecan Side Effects Report #5754209-5
Irinotecan side effect was reported by a Consumer or non-health professional from FRANCE on May 20, 2008. Male patient, weighting 167.6 lb, was diagnosed with gastric cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: atrial fibrillation , cerebrovascular accident, pulmonary embolism . Irinotecan dosage: DAILY DOSE:180MG/M2. During the same period patient was treated with FLUOROURACIL, CALCIUM FOLINATE, ATROPINE SULPHATE, ZOPHREN. Patient was hospitalized and became disabled. Patient recovered.

Irinotecan Side Effects Report #6133796-1
Irinotecan side effect was reported by a Physician from FRANCE on May 21, 2008. Female patient was diagnosed with gastric cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: dyspnoea, fall , injury, malaise, pulmonary embolism . Irinotecan dosage: 335 MG, CYCLIC. During the same period patient was treated with FLUOROURACIL, FOLINIC ACID, SOTALOL HYDROCHLORIDE, KARDEGIC. Patient was hospitalized. Patient recovered.


Irinotecan Side Effects Report #6107624-4
Irinotecan side effect was reported by a Consumer or non-health professional from GERMANY on Jan 12, 2009. Female patient was diagnosed with colorectal cancer metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: pulmonary embolism . Irinotecan dosage: unknown. During the same period patient was treated with FLUOROURACIL, CALCIUM FOLINATE, GRANISETRON, ATROPIN. Patient was hospitalized. Patient died on 10/03/2008.

Irinotecan Side Effects Report #5152578-0
Irinotecan side effect was reported by a Consumer or non-health professional from ITALY on May 15, 2002. Female patient, 65 years of age, was diagnosed with colon cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: cachexia, coma, cyanosis, diarrhoea, loss of consciousness, mucosal inflammation, neutropenia, pulmonary embolism , pulse absent. Irinotecan dosage: 280 MG (ONCE), INTRAVENOUS; SEE IMAGE. During the same period patient was treated with FLUOROURACIL, FOLINIC ACID, FOLINIC ACID, BACITRACINE, FLUCONAZOLE. Patient died on 05/14/2002.

Irinotecan Side Effects Report #4685875-3
Irinotecan side effect was reported by a Consumer or non-health professional from on June 06, 2005. Male patient, weighting 218.3 lb, was diagnosed with colon cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: pleural effusion, pulmonary embolism . Irinotecan dosage: 180 MG/M2 IV OVER 120 MINUTES ON DAY 1, EVERY 2 WEEKS X 12 CYCLES. During the same period patient was treated with LEUCOVORIN, FLUOROURACIL, COUMADIN. Patient recovered.

Irinotecan Side Effects Report #4983733-8
Irinotecan side effect was reported by a Health Professional from UNITED STATES on Apr 25, 2006. Male patient, weighting 180.3 lb, was diagnosed with anaplastic astrocytoma and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: pulmonary embolism . Irinotecan dosage: 220 MG IV (DAY 1, 8, 22 AND 29). During the same period patient was treated with AVASTIN, DEPAKOTE, DECADRON, TYLENOL EXTRA STR. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5074762-7
Irinotecan side effect was reported by a Consumer or non-health professional from SPAIN on Feb 09, 2005. Female patient, 73 years of age, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: acute pulmonary oedema, granulocytopenia, pulmonary embolism . Irinotecan dosage: 338 MG DAILY IV. During the same period patient was treated with FOLINIC ACID, FLUOROURACIL. Patient was hospitalized. Patient recovered.


Irinotecan Side Effects Report #4675917-3
Irinotecan side effect was reported by a Consumer or non-health professional from on May 26, 2005. Male patient, weighting 200.2 lb, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: blood culture positive, dyspnoea exertional, fatigue, haemoglobin decreased, neutrophil count decreased, oxygen saturation decreased, pulmonary embolism , pyrexia, red blood cell count decreased. Irinotecan dosage: 50 MG/M2 IV DAYS 1 + 8, OVER 90 MINS. During the same period patient was treated with CISPLATIN, ETOPOSIDE. Patient was hospitalized. Patient recovered.