Irinotecan and malaise Patient Reports February 12, 2012

Irinotecan Side Effects Report #4656690-1
Irinotecan side effect was reported by a Consumer or non-health professional from on Apr 27, 2005. Male patient, 73 years of age, was diagnosed with rectal cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: anorexia, blood pressure decreased, condition aggravated, disseminated intravascular coagulation, escherichia infection, malaise, metastasis, neoplasm progression, pancytopenia. Irinotecan dosage: 100 MG, INTRAVENOUS. During the same period patient was treated with ZANTAC, FLUOROURACIL, CALCIUM LEVOFOLINATE. Patient was hospitalized and became disabled. Patient died on 02/26/2005.

Irinotecan Side Effects Report #4704326-3
Irinotecan side effect was reported by a Consumer or non-health professional from on Apr 27, 2005. Male patient, 73 years of age, was diagnosed with rectal cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: alpha haemolytic streptococcal infection, anorexia, blood pressure decreased, condition aggravated, disseminated intravascular coagulation, escherichia infection, malaise, pancytopenia, sepsis . Irinotecan dosage: 100 MG INTRAVENOUS. During the same period patient was treated with FLUOROURACIL, CALCIUM FOLINATE. Patient was hospitalized and became disabled. Patient died on 02/26/2005.

Irinotecan Side Effects Report #4652214-3
Irinotecan side effect was reported by a Physician from on Apr 19, 2005. Male patient, 56 years of age, weighting 108.0 lb, was diagnosed with rectal cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: abdominal pain , anorexia, duodenal perforation, duodenal ulcer, malaise, nausea , neuroblastoma , stress . Irinotecan dosage: 60 MG INTRAVENOUS. During the same period patient was treated with METHYLPREDNISOLOONE SUCCINATE, CALCIUM LEVOFOLINATE, FENTANYL, MORPHINE, FLUOROURACIL, BETAMETHASONE, FAMOTIDINE. Patient recovered.

Irinotecan Side Effects Report #4950290-1
Irinotecan side effect was reported by a Physician from JAPAN on Mar 02, 2006. Female patient, 52 years of age, weighting 97.00 lb, was diagnosed with rectal cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: anorexia, discomfort, electrocardiogram t wave inversion, fall , loss of consciousness, malaise, nausea , urinary incontinence . Irinotecan dosage: 130 MG/BODY (INTERMITTENT), INTRAVENOUS. During the same period patient was treated with FLUOROURACIL, CALCIUM LEVOFOLINATE. Patient was hospitalized. Patient recovered.


Irinotecan Side Effects Report #4996188-4
Irinotecan side effect was reported by a Physician from JAPAN on Apr 21, 2006. Female patient, 52 years of age, weighting 97.00 lb, was diagnosed with rectal cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: anorexia, dehydration, discomfort, electrocardiogram abnormal, fall , infusion related reaction, malaise, specific gravity urine increased, syncope. Irinotecan dosage: 130 MG/BODY INTERMITTENT, INTRAVENOUS. During the same period patient was treated with FLUOROURACIL, CALCIUM LEVOFOLINATE. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5158756-9
Irinotecan side effect was reported by a Physician from JAPAN on Oct 31, 2006. Female patient, 74 years of age, weighting 88.18 lb, was diagnosed with pancreatic carcinoma, pain  and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: malaise, nausea . Irinotecan dosage: 50 MG (50 MG, 1 IN 2 WK), INTRAVENOUS. During the same period patient was treated with MORPHINE SULPHATE, OXALIPLATIN, LASIX, ALDACTONE, RABEPRAZOLE, KRESTIN, URSO. Patient recovered.

Irinotecan Side Effects Report #5072971-4
Irinotecan side effect was reported by a Physician from JAPAN on July 20, 2006. Female patient, 82 years of age, weighting 72.75 lb, was diagnosed with ovarian cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: anorexia, interstitial lung disease, leukopenia, lung infection, lymphangiosis carcinomatosa, malaise, malignant ascites, malignant neoplasm progression, pyrexia. Irinotecan dosage: 25 MG (1 IN 1 WK), INTRAVENOUS. During the same period patient was treated with LANSOPRAZOLE, JUZENTAIHOTO, ALLOID, FLUCALIN. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5117954-0
Irinotecan side effect was reported by a Physician from JAPAN on Sept 13, 2006. Female patient, 67 years of age, weighting 81.57 lb, was diagnosed with ovarian cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: anorexia, bone marrow failure, condition aggravated, infection , interstitial lung disease, malaise, malnutrition, metastases to spleen. Irinotecan dosage: unknown. During the same period patient was treated with NEUPOGEN, ETOPOSIDE, TAXOTERE. Patient was hospitalized. Patient died on 03/03/2005.

Irinotecan Side Effects Report #5150732-5
Irinotecan side effect was reported by a Consumer or non-health professional from FRANCE on Feb 04, 1998. Male patient, 44 years of age, was diagnosed with metastasis, colorectal cancer  and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: abdominal pain , asthenia, malaise, pain in jaw, pulmonary embolism . Irinotecan dosage: unknown. During the same period patient was treated with FLUOROURACIL, FOLINIC ACID. Patient died on 01/19/1998.


Irinotecan Side Effects Report #5236295-4
Irinotecan side effect was reported by a Health Professional from JAPAN on Jan 31, 2007. Male patient, weighting 88.18 lb, was diagnosed with large intestine carcinoma and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: anorexia, diarrhoea, hepatic function abnormal, large intestine perforation, malaise, pancytopenia. Irinotecan dosage: unknown. During the same period patient was treated with OMEPRAL, HYPEN, OXYCONTIN, FURTULON, MYSLEE, LASIX, NAUZELIN, LOXONIN. Patient died on 01/22/2007.

Irinotecan Side Effects Report #4692264-4
Irinotecan side effect was reported by a Physician from on June 02, 2005. Female patient, 69 years of age, was diagnosed with gastric cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: anorexia, dizziness , fatigue, malaise, oedema, oedema peripheral. Irinotecan dosage: 106 MG (INTERMITTENT), INTRAVENOUS. During the same period patient was treated with TEGAFUR. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #4699648-9
Irinotecan side effect was reported by a Physician from on June 10, 2005. Female patient, 69 years of age, was diagnosed with gastric cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: anorexia, dizziness , fatigue, malaise, oedema peripheral. Irinotecan dosage: 106 MG INTERMITTENT, INTRAVENOUS. During the same period patient was treated with TEGAFUR, MUCOSTA, GASMOTIN, ENZYMES, AMINOFLUID, GLYCERIN, HALCION. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #4709503-3
Irinotecan side effect was reported by a Physician from JAPAN on June 23, 2005. Female patient, 69 years of age, was diagnosed with gastric cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: anorexia, dizziness , fatigue, malaise, oedema peripheral. Irinotecan dosage: unknown. During the same period patient was treated with IRINOTECAN HYDROCHLORIDE SOLUTION, TEGAFUR, INTRALIPID, MUCOSTA, GASMOTIN, ENZYMES, AMINOFLUID. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #4830951-5
Irinotecan side effect was reported by a Physician from JAPAN on Oct 21, 2005. Male patient, 65 years of age, was diagnosed with gastric cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: dermatitis, dermatomyositis, effusion, malaise, rash . Irinotecan dosage: unknown. During the same period patient was treated with TEGAFUR. Patient was hospitalized. Patient recovered.


Irinotecan Side Effects Report #6102198-6
Irinotecan side effect was reported by a Physician from FRANCE on May 21, 2008. Female patient was diagnosed with gastric cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: dyspnoea, fall , injury, malaise. Irinotecan dosage: 335 MG, CYCLIC. During the same period patient was treated with FLUOROURACIL, FOLINIC ACID, SOTALOL, KARDEGIC. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #6133796-1
Irinotecan side effect was reported by a Physician from FRANCE on May 21, 2008. Female patient was diagnosed with gastric cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: dyspnoea, fall , injury, malaise, pulmonary embolism . Irinotecan dosage: 335 MG, CYCLIC. During the same period patient was treated with FLUOROURACIL, FOLINIC ACID, SOTALOL HYDROCHLORIDE, KARDEGIC. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #4928056-8
Irinotecan side effect was reported by a Physician from JAPAN on Feb 10, 2006. Female patient, 50 years of age, weighting 103.6 lb, was diagnosed with gallbladder cancer  and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: bile duct stenosis, biliary cyst, biliary dilatation, cholangitis, headache , hepatic lesion, malaise, performance status decreased. Irinotecan dosage: unknown. During the same period patient was treated with MUCOSTA, MAGNESIUM OXIDE, JUZENTAIHOTO. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #4852365-4
Irinotecan side effect was reported by a Physician from JAPAN on Nov 29, 2005. Male patient, 61 years of age, was diagnosed with colorectal cancer  and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: decreased appetite, interstitial lung disease, malaise, neutropenia. Irinotecan dosage: 100 MG (CYCLIC); INTRAVENOUS. During the same period patient was treated with ANTINEOPLASTIC AGENTS, ZANTAC, KYTRIL. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #6006395-X
Irinotecan side effect was reported by a Physician from JAPAN on Dec 01, 2008. Female patient, 47 years of age, was diagnosed with cervix carcinoma stage iii and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: blood follicle stimulating hormone increased, blood luteinising hormone increased, diarrhoea, malaise, menopausal disorder, oestradiol decreased, ovarian disorder. Irinotecan dosage: 107.5 MG. During the same period patient was treated with NEDAPLATIN. Patient recovered.


Irinotecan Side Effects Report #6006638-2
Irinotecan side effect was reported by a Physician from JAPAN on Dec 01, 2008. Female patient, 31 years of age, was diagnosed with cervix carcinoma stage i and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: blood follicle stimulating hormone increased, malaise, menopausal symptoms, oestradiol decreased, ovarian disorder. Irinotecan dosage: 360 MG;. During the same period patient was treated with NEDAPLATIN. Patient recovered.

Irinotecan Side Effects Report #5769070-2
Irinotecan side effect was reported by a Physician from JAPAN on May 29, 2008. Female patient, 47 years of age, was diagnosed with cervix carcinoma and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: blood follicle stimulating hormone increased, blood luteinising hormone increased, diarrhoea, hot flush, malaise, menopausal disorder, ovarian disorder. Irinotecan dosage: 4 DOSES, TOTAL DOSE 430 MG, INJECTION NOS. During the same period patient was treated with NEDAPLATIN. Patient recovered.

Irinotecan Side Effects Report #6006493-0
Irinotecan side effect was reported by a Physician from JAPAN on Dec 01, 2008. Female patient, 44 years of age, was diagnosed with cervix carcinoma and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: blood follicle stimulating hormone increased, blood luteinising hormone increased, malaise, menopausal symptoms, oestradiol decreased, ovarian disorder, therapeutic response decreased. Irinotecan dosage: 576 MG; IV. During the same period patient was treated with MITOMYCIN. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #4658845-9
Irinotecan side effect was reported by a Physician from on Apr 25, 2005. Male patient, 71 years of age, was diagnosed with ill-defined disorder, nausea , abdominal pain , diarrhoea and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: abdominal pain , constipation , diarrhoea, duodenal perforation, leukopenia, malaise, peritonitis, stress . Irinotecan dosage: unknown. During the same period patient was treated with DICLOFENAC SODUM, MORPHINE, BETAMETHASONE, LOPERAMIDE, CISPLATIN, PREPARATION. Patient died.

Irinotecan Side Effects Report #5900652-0
Irinotecan side effect was reported by a Pharmacist from UNITED KINGDOM on Sept 17, 2008. Male patient, 46 years of age, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: hypertension, malaise, syncope. Irinotecan dosage: unknown. During the same period patient was treated with CETUXIMAB. Patient recovered.


Irinotecan Side Effects Report #5774506-7
Irinotecan side effect was reported by a Health Professional from UNITED KINGDOM on June 06, 2008. Male patient, weighting 136.7 lb, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: dysarthria, malaise, vomiting. Irinotecan dosage: unknown. During the same period patient was treated with ATROPINE, DEXAMETHASONE, ONDANSETRON. Patient recovered.

Irinotecan Side Effects Report #4692067-0
Irinotecan side effect was reported by a Consumer or non-health professional from on June 16, 2005. Male patient, weighting 168.4 lb, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: anorexia, bone pain, constipation , dehydration, diarrhoea, flat affect, international normalised ratio increased, malaise, nausea . Irinotecan dosage: 60 MG/M2 IV OVER 90 MIN ON DAYS 1, 8 + 15 Q 4 WKS.. During the same period patient was treated with CISPLATIN. Patient recovered.