Irinotecan and hyponatraemia Patient Reports February 12, 2012

Irinotecan Side Effects Report #4633960-4
Irinotecan side effect was reported by a Health Professional from on Apr 12, 2005. Male patient, weighting 138.0 lb, was diagnosed with oesophageal carcinoma and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: dehydration, diarrhoea, hyponatraemia, renal failure acute. Irinotecan dosage: 240 MG IV. During the same period patient was treated with IMODIUM, COMPAZINE, PARAGORIC, ROXICET, OXYCODONE, CLARITIN. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #4860125-3
Irinotecan side effect was reported by a Physician from JAPAN on Dec 01, 2005. Female patient, 59 years of age, weighting 108.0 lb, was diagnosed with lung adenocarcinoma and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: convulsion, decreased activity, depressed level of consciousness, hyponatraemia, inappropriate antidiuretic hormone secretion, vomiting. Irinotecan dosage: 60 MG/M2, INTRAVENOUS. During the same period patient was treated with CISPLATIN, BICARBONATE IN PLASTIC CONTAINER, URSODIOL, MAGNESIUM OXIDE, PRIMPERAN. Patient recovered.

Irinotecan Side Effects Report #5230834-5
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Feb 05, 2007. Female patient, weighting 125.2 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: dyspnoea, headache , hyponatraemia, infection , pneumonia , pyrexia. Irinotecan dosage: 100MG/M2 DAY 1, 8, 22, 29 IV. During the same period patient was treated with TEMODAR, HYDROCHLOROTHIAZIDE, KEPPRA, CALCIUIM CETRALINE, STOOL SOFTENER. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5321374-3
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on May 07, 2007. Female patient, weighting 105.8 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: confusional state, hyperglycaemia, hyponatraemia, leukopenia, neutrophil count decreased, platelet count decreased, thrombocytopenia. Irinotecan dosage: 125MG/M2 DAY 1, 8, 22, 29 IV. During the same period patient was treated with TEMODAR, NEXIUM, PREMARIN, ALLEGRA, LOTREL. Patient was hospitalized. Patient recovered.


Irinotecan Side Effects Report #5323958-5
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on May 09, 2007. Female patient, weighting 105.8 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: confusional state, hyperglycaemia, hyponatraemia, leukopenia, thrombocytopenia, white blood cell count decreased. Irinotecan dosage: 125MG/M2 DAY 1, 8, 22, 29 IV. During the same period patient was treated with TEMODAR, NEXIUM, PREMARIN, ALLEGRA, LOTREL. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5117253-7
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Sept 27, 2006. Male patient, weighting 200.0 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: aspartate aminotransferase increased, blood alkaline phosphatase increased, diarrhoea, haemoglobin decreased, hyponatraemia, neutropenia. Irinotecan dosage: 325 MG /M2 DAY 1, 8, 22, 29 IV. During the same period patient was treated with TEMODAR, DILANTIN, LEXAPRO, PHREMILIN, OXYCODONE, DEXAMETHASONE, KEPPRA, ZANTAC. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5403922-8
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on July 31, 2007. Male patient, weighting 235.9 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: hyponatraemia, neutropenia. Irinotecan dosage: 125 MG/M2 DAY 1,8,22,29 IV. During the same period patient was treated with TEMODAR, DEXAMETHASONE, BENASEPRIL, ZANTAC, FINASTERIDE, HYDROCHLOROTHIAZIDE. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5408844-4
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on July 30, 2007. Male patient, weighting 235.9 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: hyponatraemia, neutropenia. Irinotecan dosage: unknown. During the same period patient was treated with TEMODAR, DEXAMETHASONE, BENAZEPRIL HYDROCHLORIDE, ZANTAC, FINASTERIDE, HYDROCHLOROTHIAZIDE. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5427485-6
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 24, 2007. Male patient, weighting 235.9 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: hyponatraemia, neutropenia. Irinotecan dosage: 125MG/M2 DAY 1, 8, 22, 29 IV. During the same period patient was treated with TEMODAR, DEXAMETHASONE, BENAZEPRIL HYDROCHLORIDE, FINASTERIDE, ZANTAC, POTASSIUM CHLORIDE, COREG. Patient was hospitalized. Patient recovered.


Irinotecan Side Effects Report #5427489-3
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 24, 2007. Female patient, weighting 105.8 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: confusional state, hyperglycaemia, hyponatraemia, leukopenia, neutropenia, thrombocytopenia. Irinotecan dosage: 125MG/M2 DAY 1, 8, 22, 29. During the same period patient was treated with TEMODAR, NEXIUM, PREMARIN, ALLEGRA, LOTREL. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5429276-9
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 27, 2007. Female patient, weighting 125.2 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: dyspnoea, headache , hyponatraemia, pneumonia , pyrexia. Irinotecan dosage: 100MG/M2 DAY 1, 8, 22, 29 IV. During the same period patient was treated with TEMODAR, HYDROCHLOROTHIAZIDE, DEXAMETHASONE, ZANTAC, KEPPRA. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5441112-3
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 23, 2007. Male patient, weighting 235.9 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: hyponatraemia, neutropenia. Irinotecan dosage: unknown. During the same period patient was treated with TEMODAR, DEXAMETHASONE, BENAZEPRIL HYDROCHLORIDE, ZANTAC, FINASTERIDE, HYDROCHLOROTHIAZIDE, POTASSIUM CHLORIDE. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5913407-8
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Oct 08, 2008. Male patient, weighting 235.9 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: hyponatraemia, neutropenia. Irinotecan dosage: 125MG/M2 DAY 1, 8, 22, 29 IV. During the same period patient was treated with IRINOTECAN HYDROCHLORIDE, TEMODAR, DEXAMETHASONE, BENASEPRIL, FINASTERIDE, ZANTAC, POTASSIUM CHLORIDE, COREG. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5919765-2
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Oct 07, 2008. Male patient, weighting 235.9 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: hyponatraemia, neutropenia. Irinotecan dosage: unknown. During the same period patient was treated with TEMODAR, DEXAMETHASONE, BENAZEPRIL HYDROCHLORIDE, ZANTAC, FINASTERIDE, HYDROCHLOROTHIAZIDE, POTASSIUM CHLORIDE. Patient was hospitalized. Patient recovered.


Irinotecan Side Effects Report #4615976-7
Irinotecan side effect was reported by a Physician from on Mar 08, 2005. Male patient, 67 years of age, was diagnosed with gastric cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: hyponatraemia, leukopenia, neutropenia, thrombocytopenia. Irinotecan dosage: 110 + 90 MG, INTRAVENOUS. During the same period patient was treated with CISPLATIN. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #4642357-2
Irinotecan side effect was reported by a Physician from on Apr 07, 2005. Male patient, 67 years of age, was diagnosed with gastric cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: hyponatraemia, leukopenia, neutropenia, thrombocytopenia. Irinotecan dosage: unknown. During the same period patient was treated with CISPLATIN. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5152586-X
Irinotecan side effect was reported by a Consumer or non-health professional from FRANCE on Feb 24, 1995. Male patient, 59 years of age, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: bronchospasm, bundle branch block left, cardiovascular disorder, haemoglobin decreased, hyponatraemia, platelet count increased, pneumothorax, tachycardia. Irinotecan dosage: 520 MG (EVERY 3 WEEKS), INTRAVENOUS. During the same period patient was treated with AMIODARONE, DESLANOSIDE, DIGOXIN. Patient was hospitalized. Patient died on 02/25/1995.

Irinotecan Side Effects Report #5919827-X
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Oct 06, 2008. Male patient, weighting 172.0 lb, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: cardiac failure congestive, hyponatraemia, leukopenia, neutropenic sepsis, thrombocytopenia. Irinotecan dosage: unknown. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient died on 10/06/2008.

Irinotecan Side Effects Report #5950909-2
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Nov 03, 2008. Male patient, weighting 172.0 lb, was diagnosed with nausea , anxiety , pain  and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: cardiac failure congestive, hyponatraemia, leukopenia, neutropenic sepsis, thrombocytopenia. Irinotecan dosage: unknown. During the same period patient was treated with CARBOPLATIN, COMPAZINE, PAXIL, MUCINEX, KLONOPIN, DARVOCET, PROMETHAZINE. Patient was hospitalized. Patient died on 10/06/2008.


Irinotecan Side Effects Report #6133798-5
Irinotecan side effect was reported by a Health Professional from UNITED STATES on Mar 13, 2009. Male patient, weighting 172.0 lb, was diagnosed with nausea , anxiety , pain  and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: cardiac failure congestive, hyponatraemia, leukopenia, neutropenic sepsis, thrombocytopenia. Irinotecan dosage: 60 MG/M2 (115 MG), DAYS 1, 8, 15. During the same period patient was treated with CARBOPLATIN, COMPAZINE, PAXIL, MUCINEX, KLONOPIN, DARVOCET, PROMETHAZINE. Patient was hospitalized. Patient died on 10/06/2008.