Irinotecan and febrile neutropenia Patient Reports February 12, 2012

Irinotecan Side Effects Report #5168893-0
Irinotecan side effect was reported by a Pharmacist from UNITED STATES on Dec 06, 2006. Male patient, 65 years of age, weighting 172.0 lb, was diagnosed with oesophageal carcinoma and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: blood pressure orthostatic abnormal, dehydration, diarrhoea, febrile neutropenia. Irinotecan dosage: 140 MG IV ON DAY 1, 8, 15, 22 OF 28 DAY CYCLE. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5256775-5
Irinotecan side effect was reported by a Consumer or non-health professional from CANADA on Feb 23, 2007. Male patient, weighting 148.8 lb, was diagnosed with oesophageal carcinoma and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: atrial fibrillation , chronic obstructive pulmonary disease, febrile neutropenia, ileus, ventricular tachycardia. Irinotecan dosage: unknown. During the same period patient was treated with CISPLATIN, BUSCOPAN, KYTRIL, DECADRON. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5265514-3
Irinotecan side effect was reported by a Consumer or non-health professional from CANADA on Mar 05, 2007. Male patient, weighting 148.8 lb, was diagnosed with oesophageal carcinoma and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: atrial fibrillation , chronic obstructive pulmonary disease, febrile neutropenia, ileus, ventricular tachycardia. Irinotecan dosage: unknown. During the same period patient was treated with CISPLATIN, BUSCOPAN, LOPERAMIDE HYDROCHLORIDE, TYLENOL W, KYTRIL, DECADRON, ALTACE. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5465560-0
Irinotecan side effect was reported by a Consumer or non-health professional from FRANCE on Oct 26, 1993. Female patient was diagnosed with non-hodgkin's lymphoma and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: deafness, febrile neutropenia, sepsis . Irinotecan dosage: DAILY DOSE:580MG. During the same period patient was treated with PREDNIMUSTINE, AMIKACIN, DIPHENOXYLATE, ETOPOSIDE, LOPERAMIDE, MITOGUAZONE. Patient recovered.


Irinotecan Side Effects Report #4611190-X
Irinotecan side effect was reported by a Health Professional from on Mar 15, 2005. Male patient, weighting 190.0 lb, was diagnosed with lung disorder and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: diarrhoea, enteritis, febrile neutropenia, pneumonia , renal failure, respiratory failure. Irinotecan dosage: 104 MG IV D 1 + 8. During the same period patient was treated with CISPLATIN, ETOPOSIDE, IMODIUM, PERCOCET, DECADRON, CRESTOR, EFFEXOR. Patient died on 03/06/2005.

Irinotecan Side Effects Report #5449769-8
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Sept 10, 2007. Male patient, weighting 153.4 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: band neutrophil count increased, colitis, constipation , febrile neutropenia, gastrointestinal disorder, haemoglobin decreased, hypotension, pulmonary embolism , sepsis . Irinotecan dosage: 125MG/M2 DAY 1, 8, 22, 29 IV. During the same period patient was treated with TEMODAR, VERAPAMIL, ASPIRIN, DEXAMETHASONE, DEPAKOTE, KLONOPIN. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5053467-2
Irinotecan side effect was reported by a Physician from KOREA, REPUBLIC OF on June 29, 2006. Male patient, 52 years of age, was diagnosed with gastric cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: abdominal pain upper, anaemia, diarrhoea, febrile neutropenia, lymphadenopathy, malignant neoplasm progression, neuropathy peripheral, pneumonia streptococcal. Irinotecan dosage: unknown. During the same period patient was treated with CISPLATIN, MESNA, ETOPOSIDE, PACLITAXEL. Patient was hospitalized. Patient died on 08/01/2004.

Irinotecan Side Effects Report #5085927-2
Irinotecan side effect was reported by a Physician from KOREA, REPUBLIC OF on Aug 04, 2006. Male patient, 52 years of age, was diagnosed with gastric cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: anaemia, ascites, diarrhoea, febrile neutropenia, gastric cancer, lymphadenopathy, malignant neoplasm progression, metastases to liver, neuropathy peripheral. Irinotecan dosage: unknown. During the same period patient was treated with CISPLATIN, MESNA, ETOPOSIDE, PACLITAXEL. Patient was hospitalized. Patient died on 08/01/2004.

Irinotecan Side Effects Report #4696192-X
Irinotecan side effect was reported by a Physician from on June 06, 2005. Male patient, 50 years of age, was diagnosed with gastric cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: abscess , febrile neutropenia, gastro-intestinal fistula, infection , mass, tumour necrosis. Irinotecan dosage: 72 MG (CYCLICAL) INTRAVENOUS. During the same period patient was treated with CISPLATIN, FLUOROURACIL. Patient was hospitalized. Patient recovered.


Irinotecan Side Effects Report #5156708-6
Irinotecan side effect was reported by a Physician from UNITED STATES on Nov 03, 2006. Male patient, 74 years of age, was diagnosed with colorectal cancer metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: anorexia, apnoea, diarrhoea, febrile neutropenia, gastrointestinal toxicity, haematocrit decreased, haemoglobin decreased, lymphocyte percentage decreased, monocyte count increased. Irinotecan dosage: 742 MG (CYCLICAL), INTRAVENOUS. During the same period patient was treated with CETUXIMAB, ASPIRIN, IBUPROFEN, METFORMIN, OLMESARTAN MEDOXOMIL, TEMAZEPAM, SULFISOXAZOLE. Patient was hospitalized. Patient died on 11/28/2004.

Irinotecan Side Effects Report #4701080-6
Irinotecan side effect was reported by a Physician from on June 17, 2005. Male patient, 74 years of age, was diagnosed with colorectal cancer metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: anorexia, apnoea, blood albumin decreased, blood potassium decreased, febrile neutropenia, frequent bowel movements, gastrointestinal toxicity, haematocrit decreased, incontinence. Irinotecan dosage: 742 MG (CYCLIC) INTRAVENOUS. During the same period patient was treated with CETUXIMAB, ACETYLSALICYLIC ACID SRT, IBUPROFEN, METFORMIN, OLMESARTAN MEDOXOMIL, TEMAZEPAM, SULFISOXAL. Patient was hospitalized. Patient died on 11/28/2004.

Irinotecan Side Effects Report #5290947-9
Irinotecan side effect was reported by a Consumer or non-health professional from FRANCE on Mar 30, 2007. Male patient, weighting 154.3 lb, was diagnosed with colorectal cancer metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: aphasia , colorectal cancer metastatic, condition aggravated, depressed level of consciousness, febrile bone marrow aplasia, febrile neutropenia, infection , platelet count decreased. Irinotecan dosage: unknown. During the same period patient was treated with FLUOROURACIL, CALCIUM FOLINATE, BEVACIZUMAB. Patient died on 01/01/2007.

Irinotecan Side Effects Report #5724353-7
Irinotecan side effect was reported by a Consumer or non-health professional from INDIA on Apr 21, 2008. Male patient, weighting 88.18 lb, was diagnosed with colorectal cancer metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: febrile neutropenia, hypokalaemia. Irinotecan dosage: unknown. During the same period patient was treated with FLUOROURACIL, LEUCOVORIN CALCIUM, LOPERAMIDE, GRANISETRON, PANTOPRAZOLE, LORAZEPAM, SPARFLOXACIN. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5738246-2
Irinotecan side effect was reported by a Consumer or non-health professional from INDIA on Apr 21, 2008. Male patient, weighting 88.18 lb, was diagnosed with colorectal cancer metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: febrile neutropenia, hypokalaemia. Irinotecan dosage: unknown. During the same period patient was treated with FLUOROURACIL, LEUCOVORIN CALCIUM, LOPERAMIDE, GRANISETRON, PANTOPRAZOLE, LORAZEPAM, SPARFLOXACIN. Patient was hospitalized. Patient recovered.


Irinotecan Side Effects Report #5967491-6
Irinotecan side effect was reported by a Consumer or non-health professional from INDIA on Nov 18, 2008. Male patient, weighting 88.18 lb, was diagnosed with colorectal cancer metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: febrile neutropenia, hypokalaemia. Irinotecan dosage: unknown. During the same period patient was treated with FLUOROURACIL, LEUCOVORIN CALCIUM, LOPERAMIDE, GRANISETRON, PANTOPRAZOLE, LORAZEPAM. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #4640643-3
Irinotecan side effect was reported by a Physician from on Apr 06, 2005. Female patient, 61 years of age, was diagnosed with colorectal cancer  and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: abdominal pain , abscess , disease recurrence, febrile neutropenia, hydronephrosis, hypertension, urosepsis. Irinotecan dosage: 580 MG, CYCLIC, EVERY 3 WEEKS), INTRAVENOUS. During the same period patient was treated with CAPECITABINE, MORPHINE SULPHATE, METFORMIN. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #4661107-7
Irinotecan side effect was reported by a Physician from on Apr 28, 2005. Female patient, 61 years of age, was diagnosed with colorectal cancer  and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: abdominal abscess, abdominal pain , febrile neutropenia, hydronephrosis, hypertension, urosepsis. Irinotecan dosage: 580 MG, CYCLIC, EVERY 3 WEEKS), INTRAVENOUS. During the same period patient was treated with CAPECITABINE, MORPHINE SULPHATE, METFORMIN. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #4687454-0
Irinotecan side effect was reported by a Health Professional from on June 09, 2005. Male patient, 62 years of age, weighting 189.2 lb, was diagnosed with colon cancer metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: diarrhoea, febrile neutropenia, nausea . Irinotecan dosage: 336MG ONCE Q 21 DAYS INTRAVENOU. During the same period patient was treated with CAPECITABINE, AVASTIN. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #4673296-9
Irinotecan side effect was reported by a Pharmacist from on May 24, 2005. Male patient, 76 years of age, weighting 244.0 lb, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: diarrhoea, febrile neutropenia, hypovolaemia, lethargy, mental status changes, oral intake reduced, septic shock, vomiting. Irinotecan dosage: 125 MG IV ONCE A WEEK. During the same period patient was treated with ACETAMINOPHEN, ASPIRIN, ATENOLOL, ISOSORBIDE MONONITRATE, LACTULOSE, LISINOPRIL, LORATADINE, ALBUTEROL. Patient was hospitalized. Patient recovered.


Irinotecan Side Effects Report #4880334-7
Irinotecan side effect was reported by a Physician from UNITED STATES on Dec 30, 2005. Male patient, 71 years of age, weighting 176.4 lb, was diagnosed with ill-defined disorder and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: anaemia, dyspnoea, fatigue, febrile neutropenia, hypomagnesaemia, pneumonia , thrombocytopenia. Irinotecan dosage: 100 MG/M2 (CYCLICAL), INTRAVENOUS. During the same period patient was treated with NEUPOGEN, VITAMIN, VITAMIN C, VITAMIN B12, PRIMATENE MIST, ALEVE, EXCEDRIN, DECADRON. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5115028-6
Irinotecan side effect was reported by a Physician from UNITED STATES on Sept 25, 2006. Female patient, 65 years of age, weighting 189.0 lb, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: clostridial infection, febrile neutropenia, neutrophil count increased, rebound effect, white blood cell count increased. Irinotecan dosage: 150 MG/M2 Q3W IV. During the same period patient was treated with OXALIPLATIN, NEULASTA, AVANDIA, GLIPIZIDE ER, ACIPHEX, ENALAPRIL MALEATE, BUSPIRONE, FLUOXETINE. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #4624402-3
Irinotecan side effect was reported by a Health Professional from on Mar 30, 2005. Female patient, 61 years of age, weighting 205.0 lb, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: ageusia, bronchitis , diarrhoea, fatigue, febrile neutropenia, nausea , pancytopenia, pneumonia , productive cough. Irinotecan dosage: 120 MG QD INTRAVENOU. During the same period patient was treated with CISPLATIN, ZOLPIDEM TARTRATE, HYDROCODONE, GUAFENESIN, ALBUTEROL, CLINDAMYCIN, CEFEPIME, GEMFIBROZIL. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5049588-0
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on June 30, 2006. Male patient, 59 years of age, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: diarrhoea, febrile neutropenia. Irinotecan dosage: unknown. During the same period patient was treated with ERBITUX, TEGAFUR. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5051201-3
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on June 30, 2006. Male patient, 59 years of age, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: diarrhoea, febrile neutropenia. Irinotecan dosage: unknown. During the same period patient was treated with ERBITUX, TEGAFUR. Patient was hospitalized. Patient recovered.


Irinotecan Side Effects Report #4561311-2
Irinotecan side effect was reported by a Physician from on Dec 14, 2004. Male patient, 53 years of age, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: anaemia, dysphagia, febrile neutropenia, headache , pyrexia, radiation oesophagitis, thrombocytopenia. Irinotecan dosage: 100 MG/M2 (WEEKLY), INTRAVENOUS. During the same period patient was treated with TOPOSAR, CISPLATIN, FENTANYL, MORPHINE SULPHATE, STOMATOLOGICALS, CIPROFLOXACIN, OMEPRAZOLE. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #4874749-0
Irinotecan side effect was reported by a Health Professional from UNITED STATES on Jan 05, 2006. Male patient, 47 years of age, weighting 209.0 lb, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: dyspnoea exertional, febrile neutropenia, oxygen saturation decreased, pharyngolaryngeal pain, sinus headache, sinus operation. Irinotecan dosage: 50 MGM/M2 IV Q WX4. During the same period patient was treated with CISPLATIN, PROZAC, PRILOSEC, ZESTRIL, LIPITOR, ASPIRIN, XANAX, SCOPALAMINE PATCH. Patient was hospitalized. Patient recovered.