Irinotecan and dyspnoea Patient Reports February 12, 2012

Irinotecan Side Effects Report #4624389-3
Irinotecan side effect was reported by a Pharmacist from on Mar 30, 2005. Female patient, 72 years of age, weighting 116.8 lb, was diagnosed with small intestine carcinoma stage iii and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: blood pressure systolic increased, dyspnoea, feeling abnormal, heart rate increased, hyperhidrosis, nausea , oxygen saturation decreased. Irinotecan dosage: 180 MG/M2 EVERY 2 WEEKS INTRAVENOUS. During the same period patient was treated with LEUCOVORIN CALCIUM. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5290842-5
Irinotecan side effect was reported by a Health Professional from JAPAN on Mar 29, 2007. Female patient, weighting 172.0 lb, was diagnosed with sarcoma uterus, pancytopenia and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: blood pressure decreased, coagulation test abnormal, disseminated intravascular coagulation, dyspnoea, enterococcal infection, haemoglobin decreased, leukopenia, loss of consciousness, neutropenia. Irinotecan dosage: unknown. During the same period patient was treated with FRESH FROZEN PLASMA, SEROTONE, LASIX, OXYCONTIN. Patient died on 11/29/2006.

Irinotecan Side Effects Report #5243288-X
Irinotecan side effect was reported by a Health Professional from JAPAN on Feb 09, 2007. Male patient, 73 years of age, weighting 145.5 lb, was diagnosed with rectal cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: dyspnoea, pyrexia, wheezing. Irinotecan dosage: unknown. During the same period patient was treated with FLUOROURACIL, CALCIUM FOLINATE. Patient recovered.

Irinotecan Side Effects Report #4697875-8
Irinotecan side effect was reported by a Consumer or non-health professional from on June 21, 2005. Male patient, weighting 236.6 lb, was diagnosed with rectal cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: chest pain , dyspnoea, nausea . Irinotecan dosage: 180 MG/M2 IV (DAY 1 EVERY 14 DAYS. During the same period patient was treated with LEUCOVORIN, FLUOROURACIL. Patient recovered.


Irinotecan Side Effects Report #4862633-8
Irinotecan side effect was reported by a Health Professional from UNITED STATES on Dec 19, 2005. Female patient, weighting 158.4 lb, was diagnosed with pancreatic carcinoma metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: dyspnoea, hypotension, orthopnoea, oxygen saturation abnormal, pleural effusion, renal failure acute, sepsis , therapeutic agent toxicity. Irinotecan dosage: 65MG/M2 Q 21 DAYS IV DRIP. During the same period patient was treated with DOCETAXEL. Patient was hospitalized. Patient died on 12/08/2005.

Irinotecan Side Effects Report #6003973-9
Irinotecan side effect was reported by a Physician from FRANCE on May 27, 2008. Female patient, 58 years of age, weighting 198.4 lb, was diagnosed with pancreatic carcinoma and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: ascites, confusional state, dyspnoea, hallucination, visual, hepatic function abnormal, oedema peripheral, renal failure acute. Irinotecan dosage: 2X100 MG/M2 BI-MONTHLY. During the same period patient was treated with FLUOROURACIL, FOLINIC ACID, PANTOPRAZOLE, ACETYLSALICYLIC ACID, CLOPIDOGREL SULPHATE, ACETYLSALICYLATE LYSINE, TINZAPARIN, FENTANYL. Patient was hospitalized. Patient died on 05/27/2008.

Irinotecan Side Effects Report #6024362-7
Irinotecan side effect was reported by a Physician from FRANCE on May 27, 2008. Female patient was diagnosed with pancreatic carcinoma and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: ascites, confusional state, dyspnoea, hallucination, visual, hepatic function abnormal, oedema peripheral, renal failure acute. Irinotecan dosage: 2X100 MG/M2, BI-MONTHLY. During the same period patient was treated with FLUOROURACIL, FOLINIC ACID, PANTOPRAZOLE, ACETYLSALICYLIC ACID, CLOPIDOGREL SULPHATE, ACETYLSALICYLATE LYSINE, TINZAPARIN, FENTANYL. Patient was hospitalized. Patient died on 05/27/2008.

Irinotecan Side Effects Report #4871100-7
Irinotecan side effect was reported by a Physician from JAPAN on Nov 26, 2005. Female patient, 56 years of age, weighting 113.8 lb, was diagnosed with ovarian cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: chills, dyspnoea, eosinophil count increased, hypersensitivity, interstitial lung disease, neoplasm recurrence, ovarian cancer, pyrexia. Irinotecan dosage: 80 MG (INTERMITTENT), INTRAVENOUS. During the same period patient was treated with DOCETAXEL, WARFARIN, CEFOTIAM HYDROCHLORIDE. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #4911031-7
Irinotecan side effect was reported by a Physician from JAPAN on Jan 26, 2006. Female patient, 56 years of age, weighting 113.8 lb, was diagnosed with ovarian cancer, agranulocytosis and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: alpha haemolytic streptococcal infection, bronchoalveolar lavage abnormal, chills, computerised tomogram abnormal, dyspnoea, eosinophil count increased, hypersensitivity, interstitial lung disease, mycoplasma serology positive. Irinotecan dosage: 80 MG (INTERMITTENT), INTRAVENOUS. During the same period patient was treated with DOCETAXEL, WARFARIN, PANSPORIN. Patient was hospitalized. Patient recovered.


Irinotecan Side Effects Report #4822569-5
Irinotecan side effect was reported by a Physician from JAPAN on Oct 19, 2005. Female patient was diagnosed with ovarian cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: cell marker increased, computerised tomogram abnormal, dyspnoea, eosinophil count increased, hypersensitivity, interstitial lung disease, laboratory test abnormal, lymphocyte count increased, pyrexia. Irinotecan dosage: unknown. During the same period patient was treated with DOCETAXEL. Patient recovered.

Irinotecan Side Effects Report #5121966-0
Irinotecan side effect was reported by a Physician from ITALY on Sept 20, 2006. Female patient, 66 years of age, weighting 134.5 lb, was diagnosed with non-small cell lung cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: asthenia, confusional state, dyspnoea, metastases to bone, metastases to liver, neuropathy, neurotoxicity, neutrophil percentage increased, pericardial effusion. Irinotecan dosage: 90 MG (D1, D8, D15, D22 EVERY SIX WEEKS), INTRAVENOUS. During the same period patient was treated with DOCETAXEL, ALLOPURINOL, CALCIUM, OMEPRAZEN, DELTACORTENE, TRANEX, AMINOMAL ELISIR. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #4546176-7
Irinotecan side effect was reported by a Physician from on Dec 21, 2004. Female patient, 66 years of age, weighting 134.5 lb, was diagnosed with non-small cell lung cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: asthenia, dyspnoea, lung squamous cell carcinoma stage iv, metastases to bone, metastases to liver, neurotoxicity, neutrophil percentage increased, pericardial effusion, peripheral motor neuropathy. Irinotecan dosage: 90 MG (D1, D8, D15, D22 EVERY SIX WEEKS), INTRAVENOUS. During the same period patient was treated with DOCETAXEL, ALLOPURINOL, LEKOVIT CA, OMEPRAZOLE, PREDNISONE, TRANEXAMIC ACID, THEOPHYLLINE. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #4934731-1
Irinotecan side effect was reported by a Physician from JAPAN on Dec 06, 2005. Male patient, 63 years of age, was diagnosed with non-small cell lung cancer, ill-defined disorder and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: dyspnoea, eosinophil count increased, hypoxia, interstitial lung disease, leukopenia, lymphocyte count increased, pyrexia. Irinotecan dosage: 135 MG, CYCLICAL), INTRAVENOUS. During the same period patient was treated with TEGAFUR, NARTOGRASTIM, LEVOFLOXACIN. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #4817706-2
Irinotecan side effect was reported by a Health Professional from UNITED STATES on Nov 01, 2005. Female patient, 52 years of age, was diagnosed with lung neoplasm malignant and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: dyspnoea, humerus fracture, oxygen saturation decreased, pain in extremity, pathological fracture. Irinotecan dosage: 74 MG DAY 1 + 8 IV. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient recovered.


Irinotecan Side Effects Report #5230834-5
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Feb 05, 2007. Female patient, weighting 125.2 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: dyspnoea, headache , hyponatraemia, infection , pneumonia , pyrexia. Irinotecan dosage: 100MG/M2 DAY 1, 8, 22, 29 IV. During the same period patient was treated with TEMODAR, HYDROCHLOROTHIAZIDE, KEPPRA, CALCIUIM CETRALINE, STOOL SOFTENER. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5429276-9
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 27, 2007. Female patient, weighting 125.2 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: dyspnoea, headache , hyponatraemia, pneumonia , pyrexia. Irinotecan dosage: 100MG/M2 DAY 1, 8, 22, 29 IV. During the same period patient was treated with TEMODAR, HYDROCHLOROTHIAZIDE, DEXAMETHASONE, ZANTAC, KEPPRA. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5463069-1
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Sept 18, 2007. Male patient, weighting 240.3 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: atelectasis, central nervous system infection, cerebral ventricle dilatation, chest pain , disease progression, dyspnoea, headache , lobar pneumonia, orthopnoea. Irinotecan dosage: 125MG/M2 DAY 1, 8, 22, 29 IV. During the same period patient was treated with TEMODAR, DECADRON, ZOFRAN, LORTAB, PEPCID, CELEXA, IMODIUM. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #4910735-X
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Feb 09, 2006. Female patient, weighting 185.9 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: bacteraemia, body temperature increased, confusional state, cushingoid, dyspnoea, hypotension, hypoxia, lung infiltration, pulmonary embolism . Irinotecan dosage: 2406 MG. During the same period patient was treated with CAMPTOSAR, DEXAMETHASONE PHOSPHATE, DIFLUCAN, HEPARIN, KEPPRA, LEXAPRO, SYNTHROID, TYLENOL. Patient was hospitalized. Patient died on 02/06/2006.

Irinotecan Side Effects Report #5471426-2
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Sept 17, 2007. Female patient, weighting 95.24 lb, was diagnosed with gastric cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: abdominal pain , cardiac enzymes increased, dyspnoea, gastric perforation, haemoptysis, hypokalaemia, hypotension, intestinal infarction. Irinotecan dosage: unknown. During the same period patient was treated with FLUOROURACIL, LEUCOVORIN, LORTAB, KYTRIL, OCEAN NASAL SPRAY. Patient was hospitalized. Patient died on 06/18/2007.


Irinotecan Side Effects Report #6102198-6
Irinotecan side effect was reported by a Physician from FRANCE on May 21, 2008. Female patient was diagnosed with gastric cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: dyspnoea, fall , injury, malaise. Irinotecan dosage: 335 MG, CYCLIC. During the same period patient was treated with FLUOROURACIL, FOLINIC ACID, SOTALOL, KARDEGIC. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #6133796-1
Irinotecan side effect was reported by a Physician from FRANCE on May 21, 2008. Female patient was diagnosed with gastric cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: dyspnoea, fall , injury, malaise, pulmonary embolism . Irinotecan dosage: 335 MG, CYCLIC. During the same period patient was treated with FLUOROURACIL, FOLINIC ACID, SOTALOL HYDROCHLORIDE, KARDEGIC. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #6023816-7
Irinotecan side effect was reported by a Health Professional from CANADA on Dec 17, 2008. Female patient was diagnosed with colorectal cancer metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: asthenia, dehydration, diarrhoea, dyspnoea, fatigue, feeling cold, gait disturbance. Irinotecan dosage: 350 MG ON DAY 1 EVERY 3 WEEKS. During the same period patient was treated with CAPECITABINE, OXALIPLATIN, AVASTIN, NORVASC, TRIAMTERENE AND HYDROCHLOROTHIAZIDE, ASPIRIN, NABILONE, ZOFRAN. Patient died on 12/14/2008.

Irinotecan Side Effects Report #5302733-1
Irinotecan side effect was reported by a Health Professional from UNITED KINGDOM on Apr 10, 2007. Male patient, 77 years of age, was diagnosed with colorectal cancer  and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: diarrhoea, dyspnoea, peripheral circulatory failure, pneumocystis jiroveci infection, rash , tumour perforation, ulcer , vomiting. Irinotecan dosage: unknown. During the same period patient was treated with AVASTIN. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5154528-X
Irinotecan side effect was reported by a Consumer or non-health professional from GERMANY on Jan 19, 1998. Male patient, 69 years of age, was diagnosed with colorectal cancer  and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: cardiac arrest , cheilitis, diarrhoea, dyspnoea, fall , gastroenteritis bacterial, gastroenteritis staphylococcal, haematemesis, nausea . Irinotecan dosage: 750 MG (EVERY 3 WEEKS), INTRAVENOUS. During the same period patient was treated with TROPISETRON. Patient was hospitalized. Patient died on 01/16/1998.


Irinotecan Side Effects Report #6097719-6
Irinotecan side effect was reported by a Physician from FRANCE on May 26, 2008. Female patient was diagnosed with colorectal cancer  and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: dehydration, dyspnoea. Irinotecan dosage: 315 MG, CYCLIC. During the same period patient was treated with FOLINIC ACID, FLUOROURACIL. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5127462-9
Irinotecan side effect was reported by a Physician from JAPAN on Sept 27, 2006. Female patient, 67 years of age, was diagnosed with colon cancer metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: blood bilirubin increased, blood creatinine increased, condition aggravated, diarrhoea, dyspnoea, haemoglobin decreased, hepatorenal failure, hyperthermia. Irinotecan dosage: 160 MG, INTRAVENOUS (SEE IMAGE). Patient was hospitalized. Patient died on 05/18/2004.

Irinotecan Side Effects Report #5697944-X
Irinotecan side effect was reported by a Health Professional from UNITED STATES on Apr 04, 2008. Male patient, weighting 261.5 lb, was diagnosed with colon cancer metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: atrial fibrillation , condition aggravated, dyspnoea, tachycardia. Irinotecan dosage: 432 MG IV. During the same period patient was treated with CETUXIMAB, ASPIRIN, COLACE, LASIX, GLIPIZIDE, HYDRALAZINE, LIPITOR. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5730158-3
Irinotecan side effect was reported by a Health Professional from UNITED STATES on May 05, 2008. Male patient, weighting 261.5 lb, was diagnosed with colon cancer metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: dyspnoea, tachycardia. Irinotecan dosage: 432 MG INTRAVENOUS (NOT OTHERWISE SPECIFIED). During the same period patient was treated with CETUXIMAB BRISTOL, ASPIRIN, COLACE, LASIX, GLIPIZIDE, HYDRALAZINE, LIPITOR, METFORMIN. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5154507-2
Irinotecan side effect was reported by a Consumer or non-health professional from FRANCE on May 10, 1993. Male patient, 66 years of age, was diagnosed with colon cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: anti-platelet antibody positive, bacterial infection , cardiogenic shock, central line infection, dehydration, diarrhoea, dyspnoea, escherichia infection. Irinotecan dosage: 600 MG/M*2 (EVERY 3 WEEKS), INTRAVENOUS. During the same period patient was treated with DEXAMETHASONE, GINKO BILOBA. Patient was hospitalized. Patient died on 05/16/1993.


Irinotecan Side Effects Report #4880334-7
Irinotecan side effect was reported by a Physician from UNITED STATES on Dec 30, 2005. Male patient, 71 years of age, weighting 176.4 lb, was diagnosed with ill-defined disorder and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: anaemia, dyspnoea, fatigue, febrile neutropenia, hypomagnesaemia, pneumonia , thrombocytopenia. Irinotecan dosage: 100 MG/M2 (CYCLICAL), INTRAVENOUS. During the same period patient was treated with NEUPOGEN, VITAMIN, VITAMIN C, VITAMIN B12, PRIMATENE MIST, ALEVE, EXCEDRIN, DECADRON. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5196948-3
Irinotecan side effect was reported by a Pharmacist from JAPAN on Dec 13, 2006. Male patient, 70 years of age, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: dyspnoea, interstitial lung disease, palpitations, productive cough. Irinotecan dosage: 150 MG, INTRAVENOUS. During the same period patient was treated with FLUOROURACIL, CALCIUM LEVOFOLINATE, FAMOTIDINE, GASMOTIN, MAGNESIUM OXIDE. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #4818534-4
Irinotecan side effect was reported by a Physician from UNITED STATES on Dec 21, 2004. Male patient, 65 years of age, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: bronchitis , bronchopleural fistula, dyspnoea, pleural infection, pulmonary necrosis, sinus tachycardia, supraventricular extrasystoles. Irinotecan dosage: (109 MG), INTRAVENOUS. During the same period patient was treated with CARBOPLATIN, ATIVAN, COMPAZINE, ZOFRAN, DECADRON. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #4877433-2
Irinotecan side effect was reported by a Physician from FRANCE on Dec 28, 2005. Male patient, 56 years of age, weighting 165.3 lb, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: acute respiratory failure, bone marrow failure, dyspnoea, oxygen saturation decreased, sepsis . Irinotecan dosage: 123 MG (123 MG, 1 IN 1 D), INTRAVENOUS. During the same period patient was treated with CISPLATIN, PRIMPERAN, LEXOMIL, DURAGESIC, FUROSEMIDE, VOGALENE, ATROPINE. Patient was hospitalized. Patient died on 12/20/2005.

Irinotecan Side Effects Report #4796288-8
Irinotecan side effect was reported by a Health Professional from UNITED STATES on Oct 05, 2005. Female patient, 52 years of age, weighting 204.0 lb, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: abdominal pain , back pain , constipation , dyspnoea, nausea , productive cough, sputum abnormal. Irinotecan dosage: 74 MG OVER 30-90 MIN IV. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient recovered.


Irinotecan Side Effects Report #5062328-4
Irinotecan side effect was reported by a Pharmacist from UNITED KINGDOM on July 11, 2006. Female patient, 40 years of age, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: abdominal pain , dizziness , dyspnoea, throat tightness. Irinotecan dosage: unknown. During the same period patient was treated with ATROPINE. Patient was hospitalized. Patient recovered.