Irinotecan and dysarthria Patient Reports February 12, 2012

Irinotecan Side Effects Report #4950412-2
Irinotecan side effect was reported by a Health Professional from UNITED KINGDOM on Mar 02, 2006. Female patient, 48 years of age, weighting 114.6 lb, was diagnosed with metastatic neoplasm and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: dysarthria, hyperhidrosis, salivary hypersecretion. Irinotecan dosage: 280 MG, INTRAVENOUS. During the same period patient was treated with AVASTIN, CALCIUM FOLINATE, FLUOROURACIL, OCTREOTIDE, LOPERAMIDE, MST CONTINUS, MORPHINE SULPHATE. Patient recovered.

Irinotecan Side Effects Report #5381779-1
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on July 03, 2007. Male patient, weighting 159.6 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: dysarthria, flushing, urinary incontinence . Irinotecan dosage: 325 MG/M2 DAY 1, 8, 22, 29 IV. During the same period patient was treated with TEMODAR, DILANTIN, DEXAMETHASONE, ATIVAN. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5913412-1
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Oct 08, 2008. Male patient, weighting 159.6 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, dysarthria, flushing, urinary incontinence . Irinotecan dosage: 325MG/M2 DAY 1 IV. During the same period patient was treated with TEMODAR, DILANTIN, ATIVAN, DEXAMETHASONE. Patient died on 07/03/2007.

Irinotecan Side Effects Report #5947853-3
Irinotecan side effect was reported by a Health Professional from UNITED STATES on Nov 10, 2008. Male patient, weighting 159.6 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, dysarthria, flushing, urinary incontinence . Irinotecan dosage: 325MG/M2 DAY 1 IV. During the same period patient was treated with TEMODAR, DILANTIN, ATIVAN, DEXAMETHASONE. Patient died on 07/03/2007.


Irinotecan Side Effects Report #5848856-X
Irinotecan side effect was reported by a Consumer or non-health professional from FRANCE on Aug 08, 2008. Female patient, 39 years of age, was diagnosed with endometrial cancer, colon cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: dysarthria. Irinotecan dosage: unknown. During the same period patient was treated with OXALIPLATIN, ONDANSETRON, METOCLOPRAMIDE, ATROPINE, NICARDIPINE HYDROCHLORIDE. Patient recovered.

Irinotecan Side Effects Report #5823826-6
Irinotecan side effect was reported by a Consumer or non-health professional from SPAIN on July 17, 2008. Female patient, 49 years of age, was diagnosed with colorectal cancer  and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: dysarthria. Irinotecan dosage: unknown. During the same period patient was treated with GRANISETRON, PREDNISONE, DICLOFENAC, METAMIZOLE, FAMOTIDINE, TRAMADOL. Patient recovered.

Irinotecan Side Effects Report #5570212-2
Irinotecan side effect was reported by a Pharmacist from IRELAND on Dec 11, 2007. Female patient, 45 years of age, was diagnosed with colorectal cancer  and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: dysarthria. Irinotecan dosage: unknown. Patient recovered.

Irinotecan Side Effects Report #4569509-4
Irinotecan side effect was reported by a Physician from on Jan 19, 2005. Male patient, 66 years of age, weighting 130.1 lb, was diagnosed with colon cancer metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: anorexia, aspiration, bronchopneumonia, dehydration, diarrhoea, disease progression, dysarthria, haemoglobin decreased. Irinotecan dosage: 240 MG (CYCLIC), INTRAVENOUS. During the same period patient was treated with EPINEPHRINE HYDROCHLORIDE, ACETYLSALICYLIC ACID SRT, ENALAPRIL MALEATE, NORVASC, ISOSORBIDE DINITRATE, TICLOPIDINE, MORPHINE SULPHATE, PROCHLORPERAZINE. Patient died on 07/19/2004.

Irinotecan Side Effects Report #5823827-8
Irinotecan side effect was reported by a Consumer or non-health professional from ITALY on July 17, 2008. Male patient, 64 years of age, was diagnosed with colon cancer metastatic, pain  and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: aphasia , dysarthria. Irinotecan dosage: unknown. During the same period patient was treated with ONDANSETRON, DEXAMETHASONE, ATROPINE, TRAMADOL. Patient recovered.


Irinotecan Side Effects Report #5823637-1
Irinotecan side effect was reported by a Consumer or non-health professional from NETHERLANDS on July 17, 2008. Male patient, 46 years of age, was diagnosed with colon cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: ataxia , dysarthria. Irinotecan dosage: unknown. During the same period patient was treated with GRANISETRON, DEXAMETHASONE, ATROPINE, IBUPROFEN, ACETAMINOPHEN. Patient recovered.

Irinotecan Side Effects Report #4920380-8
Irinotecan side effect was reported by a Physician from NETHERLANDS on Feb 03, 2006. Male patient, 46 years of age, was diagnosed with colon cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: coordination abnormal, dysarthria, tachyphylaxis. Irinotecan dosage: unknown. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5823497-9
Irinotecan side effect was reported by a Consumer or non-health professional from SPAIN on July 17, 2008. Female patient, 38 years of age, was diagnosed with colon cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: aphasia , dysarthria. Irinotecan dosage: unknown. During the same period patient was treated with FLUOROURACIL, ONDANSETRON, DEXAMETHASONE, ATROPINE, FENTANYL, DIAZEPAM, AMITRIPTYLINE. Patient recovered.

Irinotecan Side Effects Report #5957348-9
Irinotecan side effect was reported by a Consumer or non-health professional from NETHERLANDS on Nov 04, 2008. Male patient, 34 years of age, was diagnosed with colon cancer, metastases to liver and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: dysarthria. Irinotecan dosage: 350 MG/M2 (550 MG) (DURATION: 90 MIN EVERY 3 WEEKS). During the same period patient was treated with CEPACITABINE, OXALIPLATIN, OXYCODONE, GRANISETRON, DEXAMETHASONE. Patient recovered.

Irinotecan Side Effects Report #6049461-5
Irinotecan side effect was reported by a Consumer or non-health professional from NETHERLANDS on Jan 12, 2009. Male patient, 34 years of age, was diagnosed with colon cancer, metastases to liver and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: dysarthria. Irinotecan dosage: 350 MG/M2 (550 MG) INTRAVENOUS. During the same period patient was treated with CEPACITABINE, OXALIPLATIN, OXYCODONE, GRANISETRON, DEXAMETHASONE. Patient recovered.


Irinotecan Side Effects Report #6091219-5
Irinotecan side effect was reported by a Health Professional from NETHERLANDS on Feb 16, 2009. Male patient, 34 years of age, was diagnosed with colon cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: cholinergic syndrome, disease progression, dysarthria, nervous system disorder, neurotoxicity. Irinotecan dosage: 350 MG/M**2; IV. During the same period patient was treated with CAPECITABINE, OXALIPLATIN, DEXAMETHASONE, GRANISSTRON, OXYCODONE. Patient recovered.

Irinotecan Side Effects Report #5954776-2
Irinotecan side effect was reported by a Consumer or non-health professional from NETHERLANDS on Nov 04, 2008. Female patient, 63 years of age, was diagnosed with adenocarcinoma and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: cholinergic syndrome, dysarthria, neurotoxicity. Irinotecan dosage: 520 MG, INTRAVENOUS (NOT OTHERWISE SPECIFIED). During the same period patient was treated with ACEBUTOLOL, GRANISETRON, DEXAMETHASONE. Patient recovered.

Irinotecan Side Effects Report #6049454-8
Irinotecan side effect was reported by a Consumer or non-health professional from NETHERLANDS on Jan 12, 2009. Female patient, 63 years of age, was diagnosed with adenocarcinoma and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: cholinergic syndrome, dysarthria. Irinotecan dosage: 520 MG INTRAVENOUS. During the same period patient was treated with ACEBUTOLOL, GRANISETRON, DEXAMETHASONE. Patient recovered.

Irinotecan Side Effects Report #6091229-8
Irinotecan side effect was reported by a Health Professional from NETHERLANDS on Feb 16, 2009. Female patient, 63 years of age, was diagnosed with adenocarcinoma and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: cholinergic syndrome, dysarthria, nervous system disorder, neurotoxicity. Irinotecan dosage: 520 MG; IV. During the same period patient was treated with ACEBUTOLOL, GRANISETRON, DEXAMETHASONE. Patient recovered.

Irinotecan Side Effects Report #5823492-X
Irinotecan side effect was reported by a Consumer or non-health professional from NETHERLANDS on July 17, 2008. Female patient, 63 years of age, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: cholinergic syndrome, dysarthria, nervous system disorder. Irinotecan dosage: DAILY DOSE:520MG. During the same period patient was treated with GRANISETRON, DEXAMETHASONE. Patient recovered.


Irinotecan Side Effects Report #5520697-2
Irinotecan side effect was reported by a Pharmacist from IRELAND on Nov 07, 2007. Female patient, 45 years of age, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: dysarthria. Irinotecan dosage: unknown. Patient recovered.

Irinotecan Side Effects Report #5823494-3
Irinotecan side effect was reported by a Consumer or non-health professional from NETHERLANDS on July 17, 2008. Male patient, 34 years of age, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: dysarthria. Irinotecan dosage: unknown. During the same period patient was treated with CAPECITABINE, OXALIPLATIN, GRANISETRON, DEXAMETHASONE, OXYCODONE. Patient recovered.

Irinotecan Side Effects Report #5774506-7
Irinotecan side effect was reported by a Health Professional from UNITED KINGDOM on June 06, 2008. Male patient, weighting 136.7 lb, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: dysarthria, malaise, vomiting. Irinotecan dosage: unknown. During the same period patient was treated with ATROPINE, DEXAMETHASONE, ONDANSETRON. Patient recovered.