Irinotecan and disease progression Patient Reports February 12, 2012

Irinotecan Side Effects Report #4722529-9
Irinotecan side effect was reported by a Physician from UNITED STATES on July 07, 2005. Male patient, 57 years of age, weighting 132.3 lb, was diagnosed with squamous cell carcinoma and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: dehydration, disease progression, haemoptysis, intestinal fistula, weight decreased. Irinotecan dosage: 50 MG/M*2 (CYCLIC) INTRAVENOUS. During the same period patient was treated with CISPLATIN. Patient was hospitalized. Patient died on 11/06/2004.

Irinotecan Side Effects Report #5086168-5
Irinotecan side effect was reported by a Physician from FRANCE on Aug 09, 2006. Male patient, 64 years of age, was diagnosed with rectal cancer metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: disease progression, infection , paronychia, skin chapped. Irinotecan dosage: unknown. During the same period patient was treated with CAPECITABINE. Patient recovered.

Irinotecan Side Effects Report #4601052-6
Irinotecan side effect was reported by a Health Professional from on Mar 07, 2005. Male patient, 54 years of age, weighting 217.0 lb, was diagnosed with pancreatic carcinoma metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: bile duct obstruction, disease progression, hepatic neoplasm, hepatotoxicity, liver disorder, pyrexia. Irinotecan dosage: 160MG/M2 Q21 DAYS INTRAVENOU. During the same period patient was treated with DOCETAXEL, OXYCODONE, ALLEGRA, PLENDIL, PEPCID, OXYCONTIN, KYTRIL, DECADRON. Patient was hospitalized. Patient died on 03/03/2005.

Irinotecan Side Effects Report #6085264-3
Irinotecan side effect was reported by a Physician from FRANCE on Jan 06, 2009. Female patient, weighting 198.4 lb, was diagnosed with pancreatic carcinoma and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: disease progression, pancreatic carcinoma. Irinotecan dosage: 2X100 MG/M2, BI-MONTHLY. During the same period patient was treated with FLUOROURACIL, FOLINIC ACID, PANTOPRAZOLE, ACETYLSALICYLIC ACID, CLOPIDOGREL SULPHATE, ACETYLSALICYLATE LYSINE, TINZAPARIN, FENTANYL. Patient was hospitalized. Patient died on 05/27/2008.


Irinotecan Side Effects Report #4693777-1
Irinotecan side effect was reported by a Physician from on June 03, 2005. Female patient, 68 years of age, weighting 81.57 lb, was diagnosed with ovarian cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: anorexia, bone marrow depression, condition aggravated, cyanosis, disease progression, disease recurrence, infection , interstitial lung disease, malaise. Irinotecan dosage: unknown. During the same period patient was treated with GRAN, ETOPOSIDE, TAXOTERE. Patient was hospitalized. Patient died on 03/03/2005.

Irinotecan Side Effects Report #4628196-7
Irinotecan side effect was reported by a Health Professional from on Mar 21, 2005. Male patient, 73 years of age, was diagnosed with non-small cell lung cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: bronchial obstruction, chest x-ray abnormal, disease progression, hypoxia. Irinotecan dosage: 141 MG, INTRAVENOUS. During the same period patient was treated with BAKUMONDOUTO, CARBOCISTEINE, REBAMIPIDE, THEOPHYLLINE, SENNA, DICLOFENAC, LEVOFLOXACIN, LOPERAMIDE HYDROCHLORIDE. Patient recovered.

Irinotecan Side Effects Report #5495247-X
Irinotecan side effect was reported by a Consumer or non-health professional from JAPAN on Oct 15, 2007. Male patient, 67 years of age, was diagnosed with neoplasm and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: disease progression, leukaemia. Irinotecan dosage: unknown. During the same period patient was treated with CISPLATIN, ETOPOSIDE, DOCETAXEL. Patient died.

Irinotecan Side Effects Report #5451164-2
Irinotecan side effect was reported by a Physician from UNITED STATES on Oct 04, 2006. Female patient, 37 years of age, was diagnosed with metastatic renal cell carcinoma and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: disease progression, metastatic renal cell carcinoma, vomiting. Irinotecan dosage: unknown. During the same period patient was treated with FLUOROURACIL, LEUCOVORIN CALCIUM, AVASTIN. Patient recovered.

Irinotecan Side Effects Report #5079646-6
Irinotecan side effect was reported by a Physician from JAPAN on July 26, 2006. Male patient, 73 years of age, was diagnosed with hepatic neoplasm malignant and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: acquired diaphragmatic eventration, anaemia, atelectasis, disease progression, hepatic failure, interstitial lung disease. Irinotecan dosage: unknown. During the same period patient was treated with FURTULON, URSO, GLYCYRON, DILTIAZEM HYDROCHLORIDE, NEUQUINON, ALDACTONE, LASIX. Patient recovered.


Irinotecan Side Effects Report #5056045-4
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on July 17, 2006. Male patient, weighting 233.7 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: asthenia, blood test abnormal, convulsion, disease progression, fatigue, investigation abnormal, somnolence. Irinotecan dosage: 125MG/M2 DAY 1, 8, 22, 29 IV. During the same period patient was treated with TEMODAR, WELLBUTRIN, DECADRON, PROVIGIL, XANAX, PROTONIX. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5409417-X
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 08, 2007. Male patient, weighting 218.3 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: aphasia , confusional state, coordination abnormal, disease progression, nervous system disorder, nuclear magnetic resonance imaging brain abnormal. Irinotecan dosage: 325MG/M2 DAY 1, 8 IV. During the same period patient was treated with TEMODAR, NEXIUM, DILANTIN KAPSEAL, DEXAMETHASONE, ATIVAN, AMBIEN CR. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5427034-2
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 24, 2007. Male patient, weighting 269.0 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: blood alkaline phosphatase increased, condition aggravated, confusional state, convulsion, disease progression, haemoglobin decreased, mental status changes. Irinotecan dosage: 325MG/M2 DAY 1, 8, 22, 29 IV. During the same period patient was treated with TEMODAR, DILANTIN, PEPCID, CLORAZEPATE, DECADRON. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5427508-4
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 24, 2007. Female patient, weighting 233.7 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: asthenia, convulsion, disease progression, dysphagia, ill-defined disorder, somnolence. Irinotecan dosage: 125MG/M2 DAY 1,6,22,29 IV. During the same period patient was treated with TEMODAR, WELLBUTRIN, DECADRON, PROVIGIL, XANAX, PROTONIX. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5463069-1
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Sept 18, 2007. Male patient, weighting 240.3 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: atelectasis, central nervous system infection, cerebral ventricle dilatation, chest pain , disease progression, dyspnoea, headache , lobar pneumonia, orthopnoea. Irinotecan dosage: 125MG/M2 DAY 1, 8, 22, 29 IV. During the same period patient was treated with TEMODAR, DECADRON, ZOFRAN, LORTAB, PEPCID, CELEXA, IMODIUM. Patient was hospitalized. Patient recovered.


Irinotecan Side Effects Report #5913409-1
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Oct 08, 2008. Male patient, weighting 240.3 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: brain scan abnormal, cerebral ventricle dilatation, device malfunction, disease progression, headache , infection , malignant neoplasm progression, medical device complication, meningeal disorder. Irinotecan dosage: 125MG/M2 DAY 1, 8, 22, 29 IV. During the same period patient was treated with TEMODAR, DECADRON, LORTAB, CELEXA, ZOFRAN, PEPCID, IMODIUM. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5963709-4
Irinotecan side effect was reported by a Health Professional from UNITED STATES on Nov 21, 2008. Male patient, weighting 233.7 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: asthenia, convulsion, disease progression, nuclear magnetic resonance imaging abnormal, somnolence. Irinotecan dosage: 125MG/M2 DAY 1, 8, 22, 29 IV. During the same period patient was treated with IRINOTECAN HYDROCHLORIDE, IRINOTECAN HYDROCHLORIDE, TEMODAR, WELLBUTRIN, DECADRON, PROVIGIL. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #5963711-2
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Nov 21, 2008. Male patient, weighting 269.0 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: confusional state, disease progression. Irinotecan dosage: 325MG/M2 DAY 1, 8, 22, 29 IV. During the same period patient was treated with TEMODAR, DILANTIN, PEPCID, CLORAZEPATE DIPOTASSIUM, DECADRON. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #4965038-4
Irinotecan side effect was reported by a Physician from JAPAN on Mar 09, 2006. Female patient, 70 years of age, weighting 100.5 lb, was diagnosed with gastric cancer, ill-defined disorder and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: blood pressure decreased, chills, diarrhoea, disease progression, glycosylated haemoglobin increased, hyperglycaemia, intestinal perforation, vomiting. Irinotecan dosage: 10 MG; INTRAVENOUS. During the same period patient was treated with CISPLATIN, DEXAMETHASONE, LASIX, GLYCEOL. Patient died on 10/17/2005.

Irinotecan Side Effects Report #5465516-8
Irinotecan side effect was reported by a Consumer or non-health professional from SPAIN on Feb 07, 2002. Male patient was diagnosed with gastric cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: asthenia, disease progression, gastric cancer, odynophagia, vomiting. Irinotecan dosage: DAILY DOSE:80MG/M2-FREQ:ONCE. During the same period patient was treated with FLUOROURACIL, FOLINIC ACID, METOCLOPRAMIDE, TRAMADOL. Patient was hospitalized. Patient died on 02/26/2002.


Irinotecan Side Effects Report #4859979-6
Irinotecan side effect was reported by a Physician from JAPAN on Nov 07, 2005. Male patient, 75 years of age, weighting 132.3 lb, was diagnosed with gallbladder cancer  and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, disease progression, interstitial lung disease. Irinotecan dosage: 100 MG (1 IN 1 WEEK), INTRAVENOUS. During the same period patient was treated with GEMZAR. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #4855568-8
Irinotecan side effect was reported by a Physician from ITALY on Nov 15, 2005. Male patient, 70 years of age, was diagnosed with colorectal cancer metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: abdominal pain , asthenia, cachexia, disease progression. Irinotecan dosage: 510 MG ( 510 MG), INTRAVENOUS. During the same period patient was treated with GARDENALE, LAMICTAL, SINTROM. Patient was hospitalized. Patient died on 08/10/2005.

Irinotecan Side Effects Report #6056845-8
Irinotecan side effect was reported by a Health Professional from JAPAN on Jan 19, 2009. Female patient was diagnosed with colorectal cancer  and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: anorexia, disease progression, gastric dilatation, nausea . Irinotecan dosage: 270 MG, 1X/DAY, EVERY 2 WEEKS. During the same period patient was treated with FLUOROURACIL, SUNITINIB MALATE, BROTIZOLAM, FAMOTIDINE, MAGNESIUM OXIDE, SENNOSIDE A. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #6022337-5
Irinotecan side effect was reported by a Physician from SPAIN on Dec 15, 2008. Male patient, 68 years of age, was diagnosed with colon cancer metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: disease progression, interstitial lung disease, metastases to lung, peripheral sensory neuropathy, respiratory distress, respiratory failure. Irinotecan dosage: unknown. During the same period patient was treated with OXALIPLATIN, FOLINIC ACID, FLUOROURACIL. Patient died.

Irinotecan Side Effects Report #6055996-1
Irinotecan side effect was reported by a Consumer or non-health professional from SPAIN on Jan 13, 2009. Male patient, 68 years of age, was diagnosed with colon cancer metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: colon cancer metastatic, diffuse alveolar damage, disease progression, interstitial lung disease, left ventricular hypertrophy, malignant neoplasm progression, metastases to lung, myocardial ischaemia, neurotoxicity. Irinotecan dosage: unknown. During the same period patient was treated with OXALIPLATIN, FOLINIC ACID, FLUOROURACIL. Patient died.


Irinotecan Side Effects Report #4569509-4
Irinotecan side effect was reported by a Physician from on Jan 19, 2005. Male patient, 66 years of age, weighting 130.1 lb, was diagnosed with colon cancer metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: anorexia, aspiration, bronchopneumonia, dehydration, diarrhoea, disease progression, dysarthria, haemoglobin decreased. Irinotecan dosage: 240 MG (CYCLIC), INTRAVENOUS. During the same period patient was treated with EPINEPHRINE HYDROCHLORIDE, ACETYLSALICYLIC ACID SRT, ENALAPRIL MALEATE, NORVASC, ISOSORBIDE DINITRATE, TICLOPIDINE, MORPHINE SULPHATE, PROCHLORPERAZINE. Patient died on 07/19/2004.

Irinotecan Side Effects Report #6091219-5
Irinotecan side effect was reported by a Health Professional from NETHERLANDS on Feb 16, 2009. Male patient, 34 years of age, was diagnosed with colon cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: cholinergic syndrome, disease progression, dysarthria, nervous system disorder, neurotoxicity. Irinotecan dosage: 350 MG/M**2; IV. During the same period patient was treated with CAPECITABINE, OXALIPLATIN, DEXAMETHASONE, GRANISSTRON, OXYCODONE. Patient recovered.

Irinotecan Side Effects Report #5446639-6
Irinotecan side effect was reported by a Consumer or non-health professional from JAPAN on Aug 31, 2007. Male patient, 67 years of age, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: disease progression, leukaemia. Irinotecan dosage: unknown. During the same period patient was treated with CISPLATIN, ETOPOSIDE, DOCETAXEL. Patient died.

Irinotecan Side Effects Report #4718968-2
Irinotecan side effect was reported by a Physician from GERMANY on July 12, 2005. Male patient, 63 years of age, weighting 132.3 lb, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: convulsion, disease progression, loss of consciousness. Irinotecan dosage: 136 MG (136 MG, CYCLIC, 3 WEEKLY), INTRAVENEOUS. During the same period patient was treated with CISPLATIN, VIOXX, TRAMADOL, BISOPROLOL FUMARATE, MORPHINE SULPHATE, ALLOPURINOL, THIOCTACID. Patient was hospitalized. Patient died on 08/26/2004.

Irinotecan Side Effects Report #5055230-5
Irinotecan side effect was reported by a Physician from SWITZERLAND on July 04, 2006. Male patient, 55 years of age, weighting 198.4 lb, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: disease progression, myalgia, peripheral sensory neuropathy. Irinotecan dosage: 160 MG (FREQUENCY: CYCLIC), INTRAVENOUS. During the same period patient was treated with PLATIBLASTIN S, PLATIBLASTIN S, VIOXX. Patient recovered.


Irinotecan Side Effects Report #5154509-6
Irinotecan side effect was reported by a Physician from FRANCE on Feb 02, 1998. Male patient, 13 years of age, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: cardiac failure, disease progression, dyspnoea at rest, electrocardiogram abnormal, hepatomegaly, mitral valve incompetence, oedema peripheral, pericardial effusion, tricuspid valve incompetence. Irinotecan dosage: 600 MG, INTRAVENOUS. Patient was hospitalized. Patient recovered.

Irinotecan Side Effects Report #4598623-2
Irinotecan side effect was reported by a Health Professional from on Mar 03, 2005. Female patient, weighting 156.0 lb, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: dehydration, disease progression, pneumonia . Irinotecan dosage: 50 MG/M2 IV. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient died on 02/23/2005.