Irinotecan and convulsion 
Irinotecan and convulsion Patient Reports February 12, 2012
Irinotecan Side Effects Report #5370954-8
Irinotecan side effect was reported by a Health Professional from JAPAN on June 15, 2007. Male patient, weighting 105.8 lb, was diagnosed with rectal cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: convulsion, loss of consciousness, metabolic acidosis, nausea
. Irinotecan dosage: DAILY DOSE:220MG. During the same period patient was treated with FLUOROURACIL, LEUCOVORIN CALCIUM, NASEA, DECADRON, GLIMICRON. Patient was hospitalized. Patient recovered.Irinotecan Side Effects Report #4854891-0
Irinotecan side effect was reported by a Physician from JAPAN on Nov 16, 2005. Female patient, 59 years of age, was diagnosed with lung adenocarcinoma and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: convulsion, depressed level of consciousness, inappropriate antidiuretic hormone secretion, vomiting. Irinotecan dosage: 60 MG/M2, INTRAVENOUS. During the same period patient was treated with CISPLATIN. Patient recovered.
Irinotecan Side Effects Report #4860125-3
Irinotecan side effect was reported by a Physician from JAPAN on Dec 01, 2005. Female patient, 59 years of age, weighting 108.0 lb, was diagnosed with lung adenocarcinoma and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: convulsion, decreased activity, depressed level of consciousness, hyponatraemia, inappropriate antidiuretic hormone secretion, vomiting. Irinotecan dosage: 60 MG/M2, INTRAVENOUS. During the same period patient was treated with CISPLATIN, BICARBONATE IN PLASTIC CONTAINER, URSODIOL, MAGNESIUM OXIDE, PRIMPERAN. Patient recovered.
Irinotecan Side Effects Report #4556595-0
Irinotecan side effect was reported by a Physician from on Jan 04, 2005. Male patient, 48 years of age, weighting 123.0 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: convulsion, treatment noncompliance. Irinotecan dosage: 313.75 MG (CYCLIC), INTRAVENOUS. During the same period patient was treated with THALIDOMIDE, LEVETIRACETAM, VALPROATE, DEXAMETHASONE, ESOMEPRAZOLE, LORAZEPAM, THIAMINE. Patient was hospitalized. Patient recovered.
Irinotecan Side Effects Report #5056045-4
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on July 17, 2006. Male patient, weighting 233.7 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: asthenia, blood test abnormal, convulsion, disease progression, fatigue, investigation abnormal, somnolence. Irinotecan dosage: 125MG/M2 DAY 1, 8, 22, 29 IV. During the same period patient was treated with TEMODAR, WELLBUTRIN, DECADRON, PROVIGIL, XANAX, PROTONIX. Patient was hospitalized. Patient recovered.
Irinotecan Side Effects Report #5132948-7
Irinotecan side effect was reported by a Health Professional from UNITED STATES on Oct 19, 2006. Male patient, weighting 162.0 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: convulsion, hemiparesis. Irinotecan dosage: 644 MG IV (DAY 1, 8, 22 AND 29). During the same period patient was treated with BEVACIZUMAB, DILANTIN, PROTONIX, GLUCOPHAGE. Patient was hospitalized. Patient recovered.
Irinotecan Side Effects Report #5173437-3
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Dec 08, 2006. Male patient, weighting 269.0 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: confusional state, convulsion, glioblastoma multiforme, malignant neoplasm progression, mental status changes. Irinotecan dosage: 325MG/M2 DAY 1, 8, 22, 29 IV. During the same period patient was treated with TEMODAR, DILANTIN, DEPAKOTE, DECADRON, PEPCID, CLORAZEPATE. Patient was hospitalized. Patient recovered.
Irinotecan Side Effects Report #5409404-1
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 08, 2007. Male patient, weighting 159.6 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: brain herniation, convulsion, haemorrhage, headache
, mental status changes, nervous system disorder, posturing. Irinotecan dosage: 325MG/M2 DAY 1 IV. During the same period patient was treated with TEMODAR, DILANTIN KAPSEAL, DEXAMETHASONE, ATIVAN, DECADRON, PHENERGAN, MOTRIN, OXYCODONE. Patient died on 07/03/2007.Irinotecan Side Effects Report #5427034-2
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 24, 2007. Male patient, weighting 269.0 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: blood alkaline phosphatase increased, condition aggravated, confusional state, convulsion, disease progression, haemoglobin decreased, mental status changes. Irinotecan dosage: 325MG/M2 DAY 1, 8, 22, 29 IV. During the same period patient was treated with TEMODAR, DILANTIN, PEPCID, CLORAZEPATE, DECADRON. Patient was hospitalized. Patient recovered.
Irinotecan Side Effects Report #5427508-4
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 24, 2007. Female patient, weighting 233.7 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: asthenia, convulsion, disease progression, dysphagia, ill-defined disorder, somnolence. Irinotecan dosage: 125MG/M2 DAY 1,6,22,29 IV. During the same period patient was treated with TEMODAR, WELLBUTRIN, DECADRON, PROVIGIL, XANAX, PROTONIX. Patient was hospitalized. Patient recovered.
Irinotecan Side Effects Report #5427509-6
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 24, 2007. Male patient, weighting 159.6 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: brain herniation, cerebral haemorrhage, convulsion, headache
, incontinence, mental status changes, neoplasm progression. Irinotecan dosage: 325MG/M2 DAY 1 IV. During the same period patient was treated with TEMODAR, DILANTIN, DEXAMETHASONE, ATIVAN. Patient died on 07/03/2007.Irinotecan Side Effects Report #5870155-0
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 25, 2008. Male patient was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: convulsion, dehydration. Irinotecan dosage: DAILY DOSE:245MG-FREQ:FREQUENCY: EVERY 2 WEEKS. During the same period patient was treated with CALCIUM WITH VITAMIN D, METFORMIN, NEUTRA, BACTRIM DS, DEPAKOTE, DECADRON SRC, VICODIN. Patient was hospitalized. Patient recovered.
Irinotecan Side Effects Report #5880024-8
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Sept 04, 2008. Male patient was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: convulsion, dehydration. Irinotecan dosage: DAILY DOSE:245MG-FREQ:FREQUENCY: EVERY 2 WEEKS. During the same period patient was treated with CALCIUM WITH VITAMIN D, METFORMIN, NEUTRA, BACTRIM DS, DEPAKOTE, DECADRON SRC, VICODIN. Patient was hospitalized. Patient recovered.
Irinotecan Side Effects Report #5905255-X
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Sept 24, 2008. Male patient was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: convulsion. Irinotecan dosage: DAILY DOSE:245MG-FREQ:FREQUENCY: EVERY 2 WEEKS. During the same period patient was treated with CALCIUM WITH VITAMIN D, METFORMIN, NEUTRA, BACTRIM DS, DEPAKOTE, DECADRON, VICODIN. Patient was hospitalized. Patient recovered.
Irinotecan Side Effects Report #5963709-4
Irinotecan side effect was reported by a Health Professional from UNITED STATES on Nov 21, 2008. Male patient, weighting 233.7 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: asthenia, convulsion, disease progression, nuclear magnetic resonance imaging abnormal, somnolence. Irinotecan dosage: 125MG/M2 DAY 1, 8, 22, 29 IV. During the same period patient was treated with IRINOTECAN HYDROCHLORIDE, IRINOTECAN HYDROCHLORIDE, TEMODAR, WELLBUTRIN, DECADRON, PROVIGIL. Patient was hospitalized. Patient recovered.
Irinotecan Side Effects Report #4801624-X
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Oct 14, 2005. Male patient, weighting 183.6 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: convulsion. Irinotecan dosage: 240 MG. During the same period patient was treated with BEVACIZUMAB. Patient was hospitalized. Patient recovered.
Irinotecan Side Effects Report #4915176-7
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Feb 15, 2006. Male patient, weighting 215.4 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: convulsion, fall
, incoherent, respiration abnormal. Irinotecan dosage: 221 MG. During the same period patient was treated with TEMOZOLOMIDE, COUMADIN, DECADRON SRC, DYAZIDE, POTASSIUM CHLORIDE, PREVACID. Patient was hospitalized. Patient recovered.Irinotecan Side Effects Report #4925254-4
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Feb 23, 2006. Female patient, weighting 185.0 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: central nervous system infection, convulsion, glioblastoma multiforme, pyrexia, recurrent cancer, sepsis
, staphylococcal infection . Irinotecan dosage: 736 MG. During the same period patient was treated with TEMOZOLOMIDE. Patient was hospitalized. Patient recovered.Irinotecan Side Effects Report #4960668-8
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Mar 31, 2006. Female patient, weighting 185.0 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: convulsion, glioblastoma multiforme, headache
, neoplasm recurrence, pyrexia, staphylococcal sepsis. Irinotecan dosage: 736 MG. During the same period patient was treated with TEMOZOLOMIDE. Patient was hospitalized. Patient recovered.Irinotecan Side Effects Report #5011283-1
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on May 23, 2006. Male patient, weighting 233.7 lb, was diagnosed with glioblastoma multiforme and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: convulsion, fatigue, laboratory test abnormal, somnolence. Irinotecan dosage: 125 MG/M2 DAY 1, 8, 22, 29 IV. During the same period patient was treated with TEMODAR, WELLBUTRIN, DECADRON SRC, PROVIGIL, XANAX, PROTONIX. Patient was hospitalized. Patient recovered.
Irinotecan Side Effects Report #4877640-9
Irinotecan side effect was reported by a Physician from JAPAN on Dec 21, 2005. Male patient, 56 years of age, was diagnosed with gastric cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: abdominal pain lower, convulsion, ileus. Irinotecan dosage: (150 MG, 1 IN 1 D), INTRAVENOUS. During the same period patient was treated with TEGAFUR, FLUOROURACIL, TAXOL. Patient was hospitalized. Patient recovered.
Irinotecan Side Effects Report #4972054-5
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Mar 27, 2006. Female patient, 21 years of age, was diagnosed with ependymoma and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: abasia, anorexia, convulsion, device related infection, diarrhoea haemorrhagic, fall
, infusion related reaction, intracranial pressure increased, muscle spasms. Irinotecan dosage: 50 MG/M2 CYCLIC INTERVAL : 5 DAYS/WEEK, INTRAVENOUS. During the same period patient was treated with KEPPRA, BACTRIM, DIFLUCAN, ERLOTINIB, DECADRON. Patient was hospitalized and became disabled. Patient recovered.Irinotecan Side Effects Report #4546684-9
Irinotecan side effect was reported by a Physician from on Dec 21, 2004. Male patient, 62 years of age, was diagnosed with colorectal cancer metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: convulsion, gastrointestinal haemorrhage, multi-organ failure. Irinotecan dosage: unknown. During the same period patient was treated with FLUOROURACIL, FOLINIC ACID, SERTRALINE, IRBESARTAN, MORPHINE. Patient was hospitalized. Patient died.
Irinotecan Side Effects Report #5669932-0
Irinotecan side effect was reported by a Consumer or non-health professional from GERMANY on Mar 07, 2008. Male patient, weighting 185.2 lb, was diagnosed with colorectal cancer metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: convulsion. Irinotecan dosage: unknown. During the same period patient was treated with BEVACIZUMAB, FLUOROURACIL, FOLINIC ACID, ACETYLSALICYLIC ACID. Patient was hospitalized. Patient recovered.
Irinotecan Side Effects Report #5999132-6
Irinotecan side effect was reported by a Physician from GERMANY on Mar 07, 2008. Female patient was diagnosed with colorectal cancer metastatic and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: convulsion. Irinotecan dosage: unknown. During the same period patient was treated with BEVACIZUMAB, FLUOROURACIL, FOLINIC ACID, ACETYLSALICYLIC ACID. Patient was hospitalized. Patient recovered.
Irinotecan Side Effects Report #4989063-2
Irinotecan side effect was reported by a Health Professional from JAPAN on Apr 05, 2006. Male patient, 67 years of age, weighting 136.7 lb, was diagnosed with colon cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: acidosis, blood calcium increased, blood chloride decreased, blood potassium increased, convulsion, depressed level of consciousness, haemodialysis, heart rate decreased. Irinotecan dosage: 80 MG/M*2 (80 MG/M*2, ONE DAY), INTRAVENOUS. During the same period patient was treated with FLUOROURACIL, LEUCOVORIN CALCIUM. Patient died on 03/29/2006.
Irinotecan Side Effects Report #5018268-X
Irinotecan side effect was reported by a Health Professional from JAPAN on May 15, 2006. Male patient, 67 years of age, weighting 136.7 lb, was diagnosed with colon cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: acidosis, blood calcium increased, convulsion, depressed level of consciousness, heart rate decreased, metabolic acidosis, multi-organ failure. Irinotecan dosage: 80 MG/M*2 (80 MG/M*2, ONE DAY), INTRAVENOUS. During the same period patient was treated with FLUOROURACIL, LEUCOVORIN CALCIUM, TANKARU. Patient died on 03/29/2006.
Irinotecan Side Effects Report #5152588-3
Irinotecan side effect was reported by a Consumer or non-health professional from FRANCE on Nov 09, 1993. Female patient, 62 years of age, was diagnosed with colon cancer and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: abdominal pain
, anaemia, cardiogenic shock, cerebral haemorrhage, colon cancer, convulsion, depressed level of consciousness, gastrointestinal haemorrhage. Irinotecan dosage: 560 MG (1 IN 3 WK), INTRAVENOUS. During the same period patient was treated with ENALAPRIL MALEATE, MORPHINE, OXAZEPAM, PREDNISOLONE, RANITIDINE. Patient was hospitalized. Patient died on 10/18/1993.Irinotecan Side Effects Report #4893404-4
Irinotecan side effect was reported by a Physician from UNITED STATES on Jan 25, 2006. Female patient, weighting 15.21 lb, was diagnosed with central nervous system neoplasm and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: abnormal behaviour, central nervous system neoplasm, computerised tomogram abnormal, convulsion, disease recurrence, fatigue, headache
, malignant neoplasm progression, nodule. Irinotecan dosage: unknown. During the same period patient was treated with TEMOZOLOMIDE, VINCRISTINE, CEFIXIME CHEWABLE. Patient died on 01/16/2006.Irinotecan Side Effects Report #5558677-3
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Dec 06, 2007. Male patient, 46 years of age, was diagnosed with anaplastic astrocytoma and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: convulsion, hydrocephalus
. Irinotecan dosage: unknown. During the same period patient was treated with THALIDOMIDE. Patient was hospitalized. Patient recovered.Irinotecan Side Effects Report #5577329-7
Irinotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Dec 20, 2007. Male patient, 46 years of age, was diagnosed with anaplastic astrocytoma and was treated with Irinotecan. After drug was administered, patient experienced the following side effects: convulsion, hydrocephalus
. Irinotecan dosage: unknown. During the same period patient was treated with THALIDOMIDE. Patient was hospitalized. Patient recovered.Irinotecan Side Effects Report #4718968-2
Irinotecan side effect was reported by a Physician from GERMANY on July 12, 2005. Male patient, 63 years of age, weighting 132.3 lb, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: convulsion, disease progression, loss of consciousness. Irinotecan dosage: 136 MG (136 MG, CYCLIC, 3 WEEKLY), INTRAVENEOUS. During the same period patient was treated with CISPLATIN, VIOXX, TRAMADOL, BISOPROLOL FUMARATE, MORPHINE SULPHATE, ALLOPURINOL, THIOCTACID. Patient was hospitalized. Patient died on 08/26/2004.
Irinotecan Side Effects Report #4738644-X
Irinotecan side effect was reported by a Physician from GERMANY on July 27, 2005. Male patient, 63 years of age, weighting 132.3 lb, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: convulsion, loss of consciousness, malignant neoplasm progression, metastases to central nervous system. Irinotecan dosage: 136 MG (136 MG, CYCLIC, 3 WEEKLY), INTRAVENOUS. During the same period patient was treated with CISPLATIN, VIOXX, TRAMADOL, BISOPROLOL FUMARATE, MORPHINE SULPHATE, ALLOPURINOL, THIOCTACID. Patient was hospitalized. Patient died on 08/26/2004.
Irinotecan Side Effects Report #5806387-7
Irinotecan side effect was reported by a Consumer or non-health professional from GERMANY on July 01, 2008. Male patient, weighting 132.3 lb, was treated with Irinotecan. After drug was administered, patient experienced the following side effects: convulsion, loss of consciousness. Irinotecan dosage: unknown. During the same period patient was treated with CISPLATIN, VIOXX, TRAMAL, BISOPROLOL FUMARATE, MORPHINE SULPHATE, ALLOPURINOL, THIOCTACID. Patient was hospitalized. Patient died on 08/26/2004.
Irinotecan Side Effects Report #5927254-4
Irinotecan side effect was reported by a Health Professional from FRANCE on Oct 14, 2008. Male patient was treated with Irinotecan. After drug was administered, patient experienced the following side effects: convulsion. Irinotecan dosage: DAILY DOSE:350MG. During the same period patient was treated with FLUOROURACIL, CETUXIMAB, LEUCOVORIN CALCIUM, VERAPAMIL, PRAVASTATIN, DEXTROPROPOXYPHENE, ALLOPURINOL. Patient was hospitalized. Patient recovered.