Imatinib and pancytopenia Patient Reports February 11, 2012

Imatinib Side Effects Report #4582904-2
Imatinib side effect was reported by a Physician from on Feb 04, 2005. Female patient, 76 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: bone marrow depression, chromosome analysis abnormal, neutropenia, pancytopenia, thrombocytopenia, trisomy 8. Imatinib dosage: 600 MG TO 200 MG/DAY. Patient recovered.

Imatinib Side Effects Report #4617202-1
Imatinib side effect was reported by a Health Professional from on Mar 16, 2005. Female patient, 76 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: dry skin, hirsutism, malignant neoplasm progression, nausea , pancytopenia, porphyria non-acute, serum ferritin increased, skin discolouration. Imatinib dosage: 600 MG/D. During the same period patient was treated with DEFEROXAMINE. Patient died.

Imatinib Side Effects Report #5911913-3
Imatinib side effect was reported by a Health Professional from SPAIN on Sept 25, 2008. Male patient, 72 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: anal abscess, aplastic anaemia, enterococcal infection, fungal infection , pancytopenia, purulence, pyrexia, respiratory tract infection, stenotrophomonas infection. Imatinib dosage: 400 MG/DAY. During the same period patient was treated with ACETAMINOPHEN, IBUPROFEN, AMOXICILLIN, CLARITHROMYCIN. Patient was hospitalized. Patient recovered.

Imatinib Side Effects Report #4582920-0
Imatinib side effect was reported by a Physician from on Feb 04, 2005. Male patient, 71 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: bone marrow depression, chromosome analysis abnormal, neutropenia, pancytopenia, thrombocytopenia. Imatinib dosage: 600 MG/DAY. Patient recovered.


Imatinib Side Effects Report #4582905-4
Imatinib side effect was reported by a Physician from on Feb 04, 2005. Female patient, 66 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: bone marrow depression, chromosome analysis abnormal, neutropenia, pancytopenia, thrombocytopenia, trisomy 8. Imatinib dosage: 400 MG/DAY. Patient recovered.

Imatinib Side Effects Report #5119770-2
Imatinib side effect was reported by a Health Professional from CANADA on Sept 21, 2006. Male patient, 61 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: bone marrow failure, chromosome abnormality, chronic myeloid leukaemia, fatigue, haemoglobin decreased, marrow hyperplasia, neutropenia, pancytopenia. Imatinib dosage: unknown. Patient recovered.

Imatinib Side Effects Report #5358402-5
Imatinib side effect was reported by a Consumer or non-health professional from FRANCE on June 04, 2007. Female patient, 59 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: cytomegalovirus antibody positive, disseminated intravascular coagulation, epstein-barr virus antibody positive, hepatomegaly, lymphoproliferative disorder, night sweats, pancytopenia, pyrexia, splenomegaly. Imatinib dosage: unknown. Patient recovered.

Imatinib Side Effects Report #5382563-5
Imatinib side effect was reported by a Consumer or non-health professional from FRANCE on June 28, 2007. Female patient, 59 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: cytomegalovirus antibody positive, disseminated intravascular coagulation, epstein-barr virus antibody positive, hepatomegaly, lymphoproliferative disorder, night sweats, pancytopenia, pyrexia, splenomegaly. Imatinib dosage: unknown. Patient recovered.

Imatinib Side Effects Report #4582912-1
Imatinib side effect was reported by a Physician from on Feb 04, 2005. Female patient, 53 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: bone marrow depression, chromosome analysis abnormal, neutropenia, pancytopenia, thrombocytopenia, trisomy 8. Imatinib dosage: 400 MG/DAY. Patient recovered.


Imatinib Side Effects Report #4868107-2
Imatinib side effect was reported by a Consumer or non-health professional from UNITED STATES on Dec 19, 2005. Female patient, 52 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: anaemia haemolytic autoimmune, chronic lymphocytic leukaemia recurrent, coombs positive haemolytic anaemia, pancytopenia. Imatinib dosage: 400 MG/DAY. Patient recovered.

Imatinib Side Effects Report #4997011-4
Imatinib side effect was reported by a Consumer or non-health professional from UNITED STATES on Dec 19, 2005. Female patient, 52 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: chronic lymphocytic leukaemia recurrent, coombs positive haemolytic anaemia, pancytopenia. Imatinib dosage: 400 MG/DAY. Patient recovered.

Imatinib Side Effects Report #5129360-3
Imatinib side effect was reported by a Consumer or non-health professional from UNITED STATES on Jan 06, 2006. Female patient, 51 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: acute myeloid leukaemia, blast cell proliferation, chromosome analysis abnormal, myelodysplastic syndrome, pancytopenia. Imatinib dosage: 400 MG/DAY. Patient died.

Imatinib Side Effects Report #4883570-9
Imatinib side effect was reported by a Physician from UNITED STATES on Jan 06, 2006. Female patient, 51 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: blast cell proliferation, chromosome analysis abnormal, myelodysplastic syndrome, pancytopenia. Imatinib dosage: 400 MG/DAY. Patient recovered.

Imatinib Side Effects Report #4582919-4
Imatinib side effect was reported by a Physician from on Feb 04, 2005. Female patient, 43 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: bone marrow depression, chromosome analysis abnormal, neutropenia, pancytopenia, thrombocytopenia, trisomy 8. Imatinib dosage: 400 MG/DAY. Patient recovered.


Imatinib Side Effects Report #4563970-7
Imatinib side effect was reported by a Consumer or non-health professional from on Jan 20, 2005. Female patient, 42 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: graft versus host disease, pancytopenia, rash . Imatinib dosage: unknown. Patient died.

Imatinib Side Effects Report #5953217-9
Imatinib side effect was reported by a Health Professional from CZECH REPUBLIC on Nov 05, 2008. Female patient, 41 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: acute myeloid leukaemia, chromosome analysis abnormal, clonal evolution, pancytopenia, stem cell transplant. Imatinib dosage: unknown. Patient recovered.

Imatinib Side Effects Report #5608989-X
Imatinib side effect was reported by a Health Professional from MALTA on Jan 25, 2008. Male patient was diagnosed with chronic myeloid leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: blast crisis in myelogenous leukaemia, bone marrow failure, gastrointestinal haemorrhage, lung infection, malignant neoplasm progression, myelodysplastic syndrome, pancytopenia, pulmonary haemorrhage, thrombocytopenia. Imatinib dosage: 600 MG/D. Patient died.

Imatinib Side Effects Report #5756052-X
Imatinib side effect was reported by a Health Professional from HONG KONG on May 27, 2008. Female patient, 76 years of age, was diagnosed with chronic lymphocytic leukaemia transformation, chronic myeloid leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: biopsy lymph gland abnormal, computerised tomogram abnormal, disease progression, dry skin, haemoglobin decreased, hirsutism, nausea , pancytopenia, porphyria non-acute. Imatinib dosage: 600 MG. During the same period patient was treated with IMATINIB MESYLATE, HYDROXYUREA, INTERFERON. Patient died.

Imatinib Side Effects Report #4865944-5
Imatinib side effect was reported by a Consumer or non-health professional from JAPAN on Dec 21, 2005. Female patient, 72 years of age, was diagnosed with blast crisis in myelogenous leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: blood calcium increased, blood lactate dehydrogenase increased, bone pain, chromosome analysis abnormal, fatigue, malignant neoplasm progression, pancytopenia, parathyroid hormone-related protein increased, platelet count decreased. Imatinib dosage: 400 MG/D. Patient died on 05/31/2002.


Imatinib Side Effects Report #5693247-8
Imatinib side effect was reported by a Health Professional from UNITED STATES on Mar 25, 2008. Female patient, 62 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: chromosome analysis abnormal, cytogenetic abnormality, fluid retention, malignant neoplasm progression, monocytosis, myelodysplastic syndrome, pancytopenia. Imatinib dosage: 600 MG/D. During the same period patient was treated with CYCLOPHOSPHAMIDE, VINCRISTINE, DOXORUBICIN, DEXAMETHASONE, PREDNISONE. Patient recovered.

Imatinib Side Effects Report #5823157-4
Imatinib side effect was reported by a Health Professional from UNITED STATES on July 17, 2008. Female patient, 62 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: chromosome analysis abnormal, cytogenetic abnormality, fluid retention, malignant neoplasm progression, monocytosis, myelodysplastic syndrome, pancytopenia. Imatinib dosage: 600 MG/D. During the same period patient was treated with IMATINIB MESYLATE, IMATINIB MESYLATE, CYCLOPHOSPHAMIDE, VINCRISTINE, DOXORUBICIN, DEXAMETHASONE, PREDNISONE. Patient recovered.

Imatinib Side Effects Report #5202372-7
Imatinib side effect was reported by a Health Professional from SPAIN on Jan 03, 2007. Male patient, 43 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: hepatic failure, jaundice , lividity, multi-organ failure, pancytopenia, pneumonia , rash erythematous, renal failure, respiratory failure. Imatinib dosage: 600 MG/DAY. During the same period patient was treated with VINCRISTINE, DAUNORUBICIN, ELSPAR, CYCLOPHOSPHAMIDE, PREDNISONE, METHOTREXATE, CYTARABINE, HYDROCORTISONE. Patient died.

Imatinib Side Effects Report #5213543-8
Imatinib side effect was reported by a Health Professional from SPAIN on Jan 15, 2007. Male patient, 43 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: hepatic failure, jaundice , lividity, multi-organ failure, pancytopenia, pneumonia , rash erythematous, renal failure, respiratory failure. Imatinib dosage: 600 MG/DAY. During the same period patient was treated with VINCRISTINE, DAUNORUBICIN, CYCLOPHOSPHAMIDE, PREDNISONE, METHOTREXATE, CYTARABINE, HYDROCORTISONE. Patient died.

Imatinib Side Effects Report #5213531-1
Imatinib side effect was reported by a Physician from FRANCE on Jan 10, 2007. Female patient, 40 years of age, weighting 105.8 lb, was diagnosed with acute lymphocytic leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: febrile neutropenia, haematocrit decreased, haemoglobin decreased, mucosal inflammation, oesophagitis, pancytopenia, pharyngitis, platelet count decreased, red blood cell count decreased. Imatinib dosage: 400 MG, QD. During the same period patient was treated with PURINETHOL, METHOTREXATE. Patient was hospitalized. Patient recovered.


Imatinib Side Effects Report #5387446-2
Imatinib side effect was reported by a Physician from GERMANY on July 10, 2007. Female patient, 26 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: multi-organ failure, pancytopenia, pneumonia , sepsis . Imatinib dosage: 600 MG, QD. Patient was hospitalized. Patient died on 02/15/2007.

Imatinib Side Effects Report #5578795-3
Imatinib side effect was reported by a Pharmacist from UNITED STATES on Dec 28, 2007. Male patient, 61 years of age, was treated with Imatinib. After drug was administered, patient experienced the following side effects: anaemia, haemorrhage, pancytopenia. Imatinib dosage: 200MG HS PO. Patient recovered.

Imatinib Side Effects Report #5703664-5
Imatinib side effect was reported by a Health Professional from ISRAEL on Mar 31, 2008. Male patient, 57 years of age, was treated with Imatinib. After drug was administered, patient experienced the following side effects: bone marrow disorder, bone marrow harvest failure, pancytopenia. Imatinib dosage: 400 MG, QD. Patient recovered.

Imatinib Side Effects Report #6122161-9
Imatinib side effect was reported by a Health Professional from CHINA on Mar 09, 2009. Male patient, 23 years of age, was treated with Imatinib. After drug was administered, patient experienced the following side effects: graft versus host disease, pancytopenia. Imatinib dosage: 400 MG/ DAY. During the same period patient was treated with CYCLOSPORINE, MYCOPHENOLATE MOFETIL, METHOTREXATE. Patient recovered.

Imatinib Side Effects Report #6115397-4
Imatinib side effect was reported by a Health Professional from CHINA on Mar 09, 2009. Male patient, 20 years of age, was treated with Imatinib. After drug was administered, patient experienced the following side effects: graft versus host disease, obliterative bronchiolitis, pancytopenia. Imatinib dosage: unknown. During the same period patient was treated with CYCLOSPORINE, MYCOPHENOLATE MOFETIL, METHOTREXATE. Patient died.