Imatinib and blast crisis in myelogenous leukaemia Patient Reports February 11, 2012

Imatinib Side Effects Report #4836455-8
Imatinib side effect was reported by a Physician from SPAIN on Nov 16, 2005. Female patient, 79 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: abdominal pain , blast crisis in myelogenous leukaemia, pneumonia , pyrexia. Imatinib dosage: 400 MG/DAY. Patient was hospitalized. Patient died.

Imatinib Side Effects Report #4838410-0
Imatinib side effect was reported by a Physician from SPAIN on Nov 16, 2005. Female patient, 79 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: abdominal pain , blast crisis in myelogenous leukaemia, pneumonia , pyrexia. Imatinib dosage: 400 MG/DAY. Patient was hospitalized. Patient died.

Imatinib Side Effects Report #4838460-4
Imatinib side effect was reported by a Physician from SPAIN on Nov 16, 2005. Female patient, 79 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: abdominal pain , blast crisis in myelogenous leukaemia, pneumonia , pyrexia. Imatinib dosage: 400 MG/DAY. Patient was hospitalized. Patient died.

Imatinib Side Effects Report #5875914-6
Imatinib side effect was reported by a Consumer or non-health professional from GREECE on Sept 03, 2008. Male patient, 76 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: anaemia, blast crisis in myelogenous leukaemia, blood product transfusion dependent, cytogenetic abnormality, gastrointestinal haemorrhage, multiple myeloma , plasmacytosis. Imatinib dosage: 400 MG, QD. During the same period patient was treated with INTERFERON ALFA. Patient died.


Imatinib Side Effects Report #6070047-0
Imatinib side effect was reported by a Health Professional from GREECE on Feb 03, 2009. Male patient, 76 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: anaemia, blast crisis in myelogenous leukaemia, blood product transfusion dependent, cytogenetic abnormality, gastrointestinal haemorrhage, multiple myeloma , plasmacytosis. Imatinib dosage: 400 MG, QD. During the same period patient was treated with INTERFERON ALFA. Patient died.

Imatinib Side Effects Report #5202373-9
Imatinib side effect was reported by a Health Professional from SPAIN on Jan 03, 2007. Male patient, 66 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: blast crisis in myelogenous leukaemia, disease progression, epidermal necrosis, excessive granulation tissue, hyperplasia, lividity, lung infiltration, oedema peripheral, parakeratosis. Imatinib dosage: 100 TO 400 MG/DAY. During the same period patient was treated with IMATINIB MESYLATE, IMATINIB MESYLATE, IMATINIB MESYLATE, HYDROXYUREA. Patient died on 05/01/2003.

Imatinib Side Effects Report #5213542-6
Imatinib side effect was reported by a Health Professional from SPAIN on Jan 15, 2007. Male patient, 66 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: blast crisis in myelogenous leukaemia, disease progression, epidermal necrosis, excessive granulation tissue, hyperplasia, lividity, lung infiltration, oedema peripheral, parakeratosis. Imatinib dosage: 100 TO 400 MG/DAY. During the same period patient was treated with IMATINIB MESYLATE, IMATINIB MESYLATE, IMATINIB MESYLATE, HYDROXYUREA. Patient died on 05/01/2003.

Imatinib Side Effects Report #4864563-4
Imatinib side effect was reported by a Physician from UNITED STATES on Dec 15, 2005. Male patient, 64 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: acute myelomonocytic leukaemia, blast cells present, blast crisis in myelogenous leukaemia, blood creatinine increased, blood lactate dehydrogenase increased, blood urea increased, collapse of lung, dyspnoea, eosinophil count increased. Imatinib dosage: unknown. Patient was hospitalized. Patient died.

Imatinib Side Effects Report #5949376-4
Imatinib side effect was reported by a Consumer or non-health professional from UNITED STATES on Oct 07, 2008. Female patient, 58 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: anaemia, asthenia, blast crisis in myelogenous leukaemia, blood creatinine increased, blood urea increased, ejection fraction abnormal, enterococcal bacteraemia, haemorrhage, hypoxia. Imatinib dosage: 400 MG/DAY. During the same period patient was treated with DASATINIB. Patient was hospitalized. Patient died.


Imatinib Side Effects Report #6060818-9
Imatinib side effect was reported by a Health Professional from UNITED STATES on Jan 27, 2009. Female patient, 58 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: anaemia, asthenia, blast crisis in myelogenous leukaemia, blood creatinine increased, blood urea increased, ejection fraction abnormal, enterococcal bacteraemia, haemorrhage, hypoxia. Imatinib dosage: 400 MG/DAY. During the same period patient was treated with DASATINIB. Patient was hospitalized. Patient died.

Imatinib Side Effects Report #4593844-7
Imatinib side effect was reported by a Consumer or non-health professional from on Feb 22, 2005. Female patient, 58 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: blast crisis in myelogenous leukaemia, chromosome analysis abnormal, chronic myeloid leukaemia, leukopenia. Imatinib dosage: 400 MG/DAY. Patient died.

Imatinib Side Effects Report #5104903-4
Imatinib side effect was reported by a Health Professional from KOREA, REPUBLIC OF on Sept 08, 2006. Male patient, 42 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: back pain , blast crisis in myelogenous leukaemia, brain compression, brain mass, brain oedema, cerebral decompression, craniectomy, csf pressure increased, headache . Imatinib dosage: 300 MG/D TO 400 MG/DAY. Patient was hospitalized. Patient died.

Imatinib Side Effects Report #4586957-7
Imatinib side effect was reported by a Health Professional from on Feb 07, 2005. Male patient, 42 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: blast crisis in myelogenous leukaemia. Imatinib dosage: 400 MG/D. Patient was hospitalized. Patient recovered.

Imatinib Side Effects Report #5096361-3
Imatinib side effect was reported by a Consumer or non-health professional from ITALY on Feb 07, 2005. Male patient, 40 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: blast crisis in myelogenous leukaemia. Imatinib dosage: 400 MG/D. Patient was hospitalized. Patient recovered.


Imatinib Side Effects Report #5814976-9
Imatinib side effect was reported by a Health Professional from KUWAIT on July 15, 2008. Male patient, 37 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: blast cells present, blast crisis in myelogenous leukaemia, bone marrow transplant , chronic graft versus host disease, dyspnoea, lower respiratory tract infection, malaise, no therapeutic response. Imatinib dosage: 600 MG, DAY. During the same period patient was treated with IMATINIB MESYLATE, FLUDARABINE PHOSPHATE, CYTARABINE. Patient was hospitalized. Patient died.

Imatinib Side Effects Report #5604034-0
Imatinib side effect was reported by a Health Professional from JAPAN on Jan 14, 2008. Male patient, 35 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: blast crisis in myelogenous leukaemia, chromosome analysis abnormal, disseminated intravascular coagulation, fibrin d dimer increased, fibrin degradation products, haemorrhagic diathesis, hypovolaemic shock, malignant neoplasm progression, petechiae. Imatinib dosage: 600 MG/D. During the same period patient was treated with DANAPAROID. Patient was hospitalized. Patient recovered.

Imatinib Side Effects Report #6047996-2
Imatinib side effect was reported by a Health Professional from FRANCE on Jan 20, 2009. Female patient, 21 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: blast crisis in myelogenous leukaemia, chromosome analysis abnormal. Imatinib dosage: 400 MG/DAY. During the same period patient was treated with IMATINIB MESYLATE, NILOTINIB, DASATINIB. Patient died on 11/01/2006.

Imatinib Side Effects Report #5608989-X
Imatinib side effect was reported by a Health Professional from MALTA on Jan 25, 2008. Male patient was diagnosed with chronic myeloid leukaemia and was treated with Imatinib. After drug was administered, patient experienced the following side effects: blast crisis in myelogenous leukaemia, bone marrow failure, gastrointestinal haemorrhage, lung infection, malignant neoplasm progression, myelodysplastic syndrome, pancytopenia, pulmonary haemorrhage, thrombocytopenia. Imatinib dosage: 600 MG/D. Patient died.