Idursulfase and respiratory failure Patient Reports February 12, 2012

Idursulfase Side Effects Report #5918998-9
Idursulfase side effect was reported by a Physician from FRANCE on Sept 24, 2008. Male patient, child 6 years of age, weighting 46.30 lb, was diagnosed with mucopolysaccharidosis ii and was treated with Idursulfase. After drug was administered, patient experienced the following side effects: acute lymphocytic leukaemia, adenovirus infection, bone marrow transplant , graft versus host disease, mediastinal disorder, mutism, neurological symptom, respiratory failure. Idursulfase dosage: 0.5 MG/KG, 1X/WK, IV DRIP. Patient was hospitalized. Patient died on 02/01/2008.

Idursulfase Side Effects Report #5678103-3
Idursulfase side effect was reported by a Physician from JAPAN on Mar 05, 2008. Male patient, 21 years of age, weighting 48.50 lb, was diagnosed with mucopolysaccharidosis ii and was treated with Idursulfase. After drug was administered, patient experienced the following side effects: blood urea increased, cardiac failure, hepatic enzyme increased, pulmonary congestion, respiratory failure, urine output decreased, white blood cell count increased. Idursulfase dosage: 12 MG, 1X/WEEK, IV DRIP. During the same period patient was treated with CARBOCISTEINE, CLARITHROMYCIN. Patient died on 02/15/2008.

Idursulfase Side Effects Report #5678101-X
Idursulfase side effect was reported by a Physician from JAPAN on Mar 05, 2008. Male patient, 17 years of age, was diagnosed with mucopolysaccharidosis ii and was treated with Idursulfase. After drug was administered, patient experienced the following side effects: respiratory failure. Idursulfase dosage: 18 MG, 1XWEEK, IV DRIP. Patient died on 03/04/2008.

Idursulfase Side Effects Report #5657946-6
Idursulfase side effect was reported by a Physician from JAPAN on Feb 22, 2008. Male patient, 21 years of age, weighting 48.50 lb, was diagnosed with mucopolysaccharidosis i and was treated with Idursulfase. After drug was administered, patient experienced the following side effects: blood urea increased, cardiopulmonary failure, hepatic enzyme increased, oedema, pulmonary congestion, respiratory failure, urine output decreased, white blood cell count increased. Idursulfase dosage: 12 MG, 1X/WEEK, IV DRIP. During the same period patient was treated with CARBOCISTEINE, CLARITHROMYCIN. Patient died on 02/15/2008.


Idursulfase Side Effects Report #5702998-8
Idursulfase side effect was reported by a Consumer or non-health professional from JAPAN on Mar 27, 2008. Male patient, 22 years of age, was treated with Idursulfase. After drug was administered, patient experienced the following side effects: respiratory failure. Idursulfase dosage: 18 MG, 1X/WEEK, IV DRIP. Patient died on 03/24/2008.

Idursulfase Side Effects Report #5705270-5
Idursulfase side effect was reported by a Consumer or non-health professional from JAPAN on Apr 03, 2008. Male patient, 22 years of age, weighting 79.37 lb, was treated with Idursulfase. After drug was administered, patient experienced the following side effects: respiratory failure. Idursulfase dosage: 18 MG, 1X/WEEK, IV DRIP. Patient died on 03/24/2008.