Idursulfase and infusion related reaction Patient Reports February 12, 2012

Idursulfase Side Effects Report #5765803-X
Idursulfase side effect was reported by a Physician from JAPAN on May 01, 2008. Male patient, child 7 years of age, weighting 61.73 lb, was diagnosed with mucopolysaccharidosis ii and was treated with Idursulfase. After drug was administered, patient experienced the following side effects: erythema, infusion related reaction, morose, salivary hypersecretion, urticaria. Idursulfase dosage: 12 MG, 1X/WEEK, IV DRIP. Patient recovered.

Idursulfase Side Effects Report #6016892-9
Idursulfase side effect was reported by a Physician from JAPAN on Dec 05, 2008. Male patient, child 7 years of age, weighting 61.73 lb, was diagnosed with mucopolysaccharidosis ii and was treated with Idursulfase. After drug was administered, patient experienced the following side effects: anaphylactic reaction, erythema, infusion related reaction, morose, pruritus, salivary hypersecretion, urticaria. Idursulfase dosage: 12 MG, 1X WEEK, IV DRIP. Patient recovered.

Idursulfase Side Effects Report #5389799-8
Idursulfase side effect was reported by a Physician from TAIWAN, PROVINCE OF CHINA on June 28, 2007. Male patient, child 5 years of age, weighting 39.68 lb, was diagnosed with mucopolysaccharidosis ii and was treated with Idursulfase. After drug was administered, patient experienced the following side effects: infusion related reaction, pruritus, urticaria. Idursulfase dosage: (0.5 MG/KG, 1 IN 1 WK), INTRAVENOUS DRIP. During the same period patient was treated with CAPOTEN. Patient recovered.

Idursulfase Side Effects Report #5427731-9
Idursulfase side effect was reported by a Physician from UNITED STATES on Aug 07, 2007. Male patient, child 5 years of age, weighting 59.08 lb, was diagnosed with mucopolysaccharidosis ii and was treated with Idursulfase. After drug was administered, patient experienced the following side effects: apnoea, chills, cough, crying, erythema, hypertension, infusion related reaction, oxygen saturation decreased, pallor. Idursulfase dosage: (12 MG, 1 IN 1 WK), INTRAVENOUS DRIP. During the same period patient was treated with CLARITIN, ATENOLOL. Patient recovered.


Idursulfase Side Effects Report #5430347-1
Idursulfase side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 24, 2007. Male patient, child 5 years of age, weighting 59.08 lb, was diagnosed with mucopolysaccharidosis ii and was treated with Idursulfase. After drug was administered, patient experienced the following side effects: apnoea, chills, cough, crying, erythema, hypertension, infusion related reaction, peripheral coldness, rash . Idursulfase dosage: 12 MG, 1 IN 1 WK, INTRAVENOUS DRIP; 12 MG, 1 IN 1 WK, INTRAVENOUS DRIP. During the same period patient was treated with CLARITIN, ATENOILOL. Patient recovered.

Idursulfase Side Effects Report #5388697-3
Idursulfase side effect was reported by a Consumer or non-health professional from JAPAN on June 27, 2007. Male patient, 42 years of age, weighting 103.6 lb, was diagnosed with mucopolysaccharidosis ii and was treated with Idursulfase. After drug was administered, patient experienced the following side effects: blood immunoglobulin e increased, depressed level of consciousness, headache , hypotension, infusion related reaction, nausea , pulse pressure decreased, shock. Idursulfase dosage: (0.5 MG/KG, 1 IN 1WK), INTRAVENOUS DRIP. During the same period patient was treated with VERAPAMIL, OMEPRAZOLE, ASPIRIN, DIGOXIN, TORSEMIDE, PIMOBENDAN, LEVOTHYROXINE, HYDROCORTISONE. Patient was hospitalized. Patient recovered.

Idursulfase Side Effects Report #5599306-2
Idursulfase side effect was reported by a Physician from JAPAN on Jan 04, 2008. Male patient, child 4 years of age, weighting 48.50 lb, was diagnosed with mucopolysaccharidosis ii and was treated with Idursulfase. After drug was administered, patient experienced the following side effects: bronchitis , diarrhoea, infusion related reaction. Idursulfase dosage: 12 MG, 1X/WEEK, IV DRIP. Patient was hospitalized. Patient recovered.

Idursulfase Side Effects Report #5331731-7
Idursulfase side effect was reported by a Physician from ITALY on Apr 19, 2007. Male patient, 19 years of age, weighting 115.7 lb, was diagnosed with mucopolysaccharidosis ii and was treated with Idursulfase. After drug was administered, patient experienced the following side effects: bacteraemia, infusion related reaction, poor venous access, pyrexia, staphylococcal infection . Idursulfase dosage: unknown. Patient was hospitalized. Patient recovered.

Idursulfase Side Effects Report #5331729-9
Idursulfase side effect was reported by a Consumer or non-health professional from UNITED STATES on Apr 05, 2007. Male patient, 15 years of age, weighting 98.33 lb, was diagnosed with mucopolysaccharidosis ii and was treated with Idursulfase. After drug was administered, patient experienced the following side effects: aspiration, chills, flushing, infusion related reaction, nausea , pneumonia , rash , rash erythematous, rash papular. Idursulfase dosage: (23 MG, 1 IN 1 WK), INTRAVENOUS DRIP. Patient was hospitalized. Patient recovered.


Idursulfase Side Effects Report #5331726-3
Idursulfase side effect was reported by a Consumer or non-health professional from UNITED STATES on Jan 16, 2007. Male patient, child 10 years of age, weighting 60.63 lb, was diagnosed with mucopolysaccharidosis ii and was treated with Idursulfase. After drug was administered, patient experienced the following side effects: anaphylactoid reaction, chest discomfort, erythema, infusion related reaction, urticaria, wheezing. Idursulfase dosage: (13.5 MG, 1 IN 1 WK), INTRAVENOUS DRIP. Patient recovered.