Idursulfase and hepatic enzyme increased Patient Reports February 12, 2012

Idursulfase Side Effects Report #5678103-3
Idursulfase side effect was reported by a Physician from JAPAN on Mar 05, 2008. Male patient, 21 years of age, weighting 48.50 lb, was diagnosed with mucopolysaccharidosis ii and was treated with Idursulfase. After drug was administered, patient experienced the following side effects: blood urea increased, cardiac failure, hepatic enzyme increased, pulmonary congestion, respiratory failure, urine output decreased, white blood cell count increased. Idursulfase dosage: 12 MG, 1X/WEEK, IV DRIP. During the same period patient was treated with CARBOCISTEINE, CLARITHROMYCIN. Patient died on 02/15/2008.

Idursulfase Side Effects Report #5657946-6
Idursulfase side effect was reported by a Physician from JAPAN on Feb 22, 2008. Male patient, 21 years of age, weighting 48.50 lb, was diagnosed with mucopolysaccharidosis i and was treated with Idursulfase. After drug was administered, patient experienced the following side effects: blood urea increased, cardiopulmonary failure, hepatic enzyme increased, oedema, pulmonary congestion, respiratory failure, urine output decreased, white blood cell count increased. Idursulfase dosage: 12 MG, 1X/WEEK, IV DRIP. During the same period patient was treated with CARBOCISTEINE, CLARITHROMYCIN. Patient died on 02/15/2008.