Hydroxyurea and pancytopenia Patient Reports February 11, 2012

Hydroxyurea Side Effects Report #6043683-5
Hydroxyurea side effect was reported by a Health Professional from UNITED STATES on Jan 13, 2009. Female patient, 84 years of age, was diagnosed with thrombocythaemia and was treated with Hydroxyurea. After drug was administered, patient experienced the following side effects: pancytopenia, thrombocytopenia. Hydroxyurea dosage: unknown. During the same period patient was treated with ASPIRIN. Patient died.

Hydroxyurea Side Effects Report #6046016-3
Hydroxyurea side effect was reported by a Physician from UNITED STATES on Jan 06, 2009. Female patient, 84 years of age, was diagnosed with essential thrombocythaemia and was treated with Hydroxyurea. After drug was administered, patient experienced the following side effects: asthenia, blood creatine increased, depressed level of consciousness, haemodynamic instability, hypoaesthesia, hypotension, hypoxia, pancytopenia, tachypnoea. Hydroxyurea dosage: (500 MG BID ORAL), (1 G BID ORAL). During the same period patient was treated with ASPIRIN. Patient was hospitalized. Patient died.

Hydroxyurea Side Effects Report #4737994-0
Hydroxyurea side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 05, 2005. Male patient, 79 years of age, weighting 136.7 lb, was diagnosed with essential thrombocythaemia and was treated with Hydroxyurea. After drug was administered, patient experienced the following side effects: mental status changes, neuropathic pain, pancytopenia, sedation. Hydroxyurea dosage: 500 MG PO BID. Patient died.

Hydroxyurea Side Effects Report #4664149-0
Hydroxyurea side effect was reported by a Pharmacist from on May 16, 2005. Male patient, 58 years of age, was diagnosed with essential thrombocythaemia, alcoholism , dysthymic disorder, major depression, post-traumatic stress disorder  and was treated with Hydroxyurea. After drug was administered, patient experienced the following side effects: haematocrit decreased, pancytopenia, white blood cell count abnormal. Hydroxyurea dosage: 500MG PO TID. During the same period patient was treated with TOPIRAMATE, METOPROLOL, CITALOPRAM, MIRTAZAPINE. Patient was hospitalized. Patient recovered.