Holoxan and aphasia Patient Reports February 12, 2012

Holoxan Side Effects Report #6049943-6
Holoxan side effect was reported by a Health Professional from FRANCE on Jan 19, 2009. Male patient, 62 years of age, was diagnosed with sarcoma and was treated with Holoxan. After drug was administered, patient experienced the following side effects: aphasia , asterixis, confusional state, extrapyramidal disorder, toxic encephalopathy. Holoxan dosage: unknown. During the same period patient was treated with DOXORUBICIN, ZOPHREN, EMEND. Patient was hospitalized. Patient recovered.

Holoxan Side Effects Report #6080158-1
Holoxan side effect was reported by a Health Professional from FRANCE on Feb 06, 2009. Male patient, 62 years of age, was diagnosed with sarcoma and was treated with Holoxan. After drug was administered, patient experienced the following side effects: aphasia , asterixis, confusional state, extrapyramidal disorder, toxic encephalopathy. Holoxan dosage: unknown. During the same period patient was treated with DOXORUBICIN, ZOPHREN, EMEND. Patient was hospitalized. Patient recovered.

Holoxan Side Effects Report #6103039-3
Holoxan side effect was reported by a Health Professional from FRANCE on Feb 23, 2009. Male patient, 62 years of age, was diagnosed with sarcoma and was treated with Holoxan. After drug was administered, patient experienced the following side effects: aphasia , asterixis, confusional state, extrapyramidal disorder, toxic encephalopathy. Holoxan dosage: unknown. During the same period patient was treated with DOXORUBICIN, ZOPHREN, EMEND. Patient was hospitalized. Patient recovered.

Holoxan Side Effects Report #5136490-9
Holoxan side effect was reported by a Consumer or non-health professional from UNITED STATES on Sept 06, 2006. Male patient, 74 years of age, weighting 147.7 lb, was diagnosed with non-hodgkin's lymphoma and was treated with Holoxan. After drug was administered, patient experienced the following side effects: abnormal behaviour, angiopathy, aphasia , cerebral thrombosis, confusional state, encephalopathy, hemiparesis, impaired self-care. Holoxan dosage: unknown. During the same period patient was treated with UROMITEXAN, VEPESID. Patient was hospitalized and became disabled. Patient recovered.


Holoxan Side Effects Report #5683025-8
Holoxan side effect was reported by a Consumer or non-health professional from GERMANY on Mar 19, 2008. Female patient, 56 years of age, was diagnosed with multiple myeloma , gastritis prophylaxis and was treated with Holoxan. After drug was administered, patient experienced the following side effects: aphasia , coma, neurotoxicity, toxic encephalopathy. Holoxan dosage: unknown. During the same period patient was treated with ETOPOSIDE, EPIRUBICIN, UROMITEXAN, PANTOZOL. Patient was hospitalized. Patient recovered.

Holoxan Side Effects Report #4619244-9
Holoxan side effect was reported by a Health Professional from on Mar 17, 2005. Female patient, 70 years of age, was diagnosed with endometrial cancer and was treated with Holoxan. After drug was administered, patient experienced the following side effects: agitation, aphasia , blood creatinine increased, confusional state, encephalopathy, somnolence. Holoxan dosage: unknown. During the same period patient was treated with UROMITEXAN, DOXORUBICIN. Patient was hospitalized. Patient recovered.