Herceptin and disease progression Patient Reports February 11, 2012

Herceptin Side Effects Report #5362986-0
Herceptin side effect was reported by a Consumer or non-health professional from UNITED STATES on June 11, 2007. Female patient was diagnosed with metastatic neoplasm and was treated with Herceptin. After drug was administered, patient experienced the following side effects: disease progression. Herceptin dosage: unknown. During the same period patient was treated with LAPATINIB. Patient died on 01/01/2007.

Herceptin Side Effects Report #5369877-X
Herceptin side effect was reported by a Consumer or non-health professional from UNITED STATES on June 11, 2007. Female patient was diagnosed with metastatic neoplasm and was treated with Herceptin. After drug was administered, patient experienced the following side effects: disease progression. Herceptin dosage: unknown. During the same period patient was treated with LAPATINIB. Patient died on 01/01/2007.

Herceptin Side Effects Report #5271202-X
Herceptin side effect was reported by a Physician from JAPAN on Mar 01, 2007. Male patient, 71 years of age, weighting 143.3 lb, was diagnosed with gastric cancer and was treated with Herceptin. After drug was administered, patient experienced the following side effects: arthritis

, disease progression, gastrointestinal haemorrhage, gout

, hepatic lesion, neutrophil count increased, pyrexia, renal impairment, white blood cell count increased. Herceptin dosage: 520 MG, Q3W, INTRAVENOUS. During the same period patient was treated with CAPECITABINE, CISPLATIN, FERROUS CITRATE, ZOLPIDEM TARTRATE, DIFLUCORTOLONE VALERATE, DICYCLOMINE, CETRAXATE HYDROCHLORIDE. Patient was hospitalized. Patient recovered.

Herceptin Side Effects Report #5201908-X
Herceptin side effect was reported by a Physician from JAPAN on Dec 21, 2006. Female patient, 54 years of age, weighting 99.65 lb, was diagnosed with gastric cancer and was treated with Herceptin. After drug was administered, patient experienced the following side effects: ascites, disease progression, hypertension, nausea

, reversible posterior leukoencephalopathy syndrome, visual acuity reduced. Herceptin dosage: 8 MG/KG, SINGLE, INTRAVENOUS. During the same period patient was treated with CAPECITABINE, CISPLATIN, HYPERALIMENTATION, INSULIN, OMEPRAZOLE. Patient was hospitalized. Patient recovered.

Herceptin Side Effects Report #5223308-9
Herceptin side effect was reported by a Physician from JAPAN on Jan 10, 2007. Female patient, 54 years of age, weighting 99.65 lb, was diagnosed with gastric cancer and was treated with Herceptin. After drug was administered, patient experienced the following side effects: ascites, disease progression, gastric cancer, grand mal convulsion, hypertension, nausea

, reversible posterior leukoencephalopathy syndrome, visual acuity reduced. Herceptin dosage: unknown. During the same period patient was treated with CAPECITABINE, CISPLATIN, HYPERALIMENTATION, INSULIN, OMEPRAZOLE, SPIRONOLACTONE, LANSOPRAZOLE. Patient was hospitalized and became disabled. Patient recovered.

Herceptin Side Effects Report #5158124-X
Herceptin side effect was reported by a Physician from JAPAN on Oct 30, 2006. Female patient, 54 years of age, weighting 99.65 lb, was diagnosed with gastric cancer and was treated with Herceptin. After drug was administered, patient experienced the following side effects: ascites, disease progression, hypertension, nausea

, reversible posterior leukoencephalopathy syndrome, visual acuity reduced. Herceptin dosage: 8 MG/KG, SINGLE, INTRAVEOUS; 6MG, 3/WEEK, INTRAVENOUS. During the same period patient was treated with CAPECITABINE, CISPLATIN, HYPERALIMENTATION. Patient was hospitalized. Patient recovered.

Herceptin Side Effects Report #5164885-6
Herceptin side effect was reported by a Physician from JAPAN on Nov 09, 2006. Female patient, 54 years of age, weighting 99.65 lb, was diagnosed with gastric cancer and was treated with Herceptin. After drug was administered, patient experienced the following side effects: ascites, disease progression, hypertension, nausea

, reversible posterior leukoencephalopathy syndrome. Herceptin dosage: unknown. During the same period patient was treated with CAPECITABINE, CISPLATIN, HYPERALIMENTATION, INSULIN, OMEPRAZOLE. Patient was hospitalized. Patient recovered.

Herceptin Side Effects Report #5182643-3
Herceptin side effect was reported by a Consumer or non-health professional from UNITED STATES on Nov 30, 2006. Female patient, 72 years of age, was diagnosed with breast cancer metastatic and was treated with Herceptin. After drug was administered, patient experienced the following side effects: coronary artery occlusion, disease progression. Herceptin dosage: 2 MG/KG, 1/WEEK, INTRAVENOUS; 1/MONTH, INTRAVENOUS. Patient recovered.

Herceptin Side Effects Report #4947269-2
Herceptin side effect was reported by a Consumer or non-health professional from UNITED STATES on Mar 01, 2006. Female patient, 72 years of age, was diagnosed with breast cancer metastatic and was treated with Herceptin. After drug was administered, patient experienced the following side effects: cardiac disorder, disease progression, hypersensitivity, infusion related reaction. Herceptin dosage: 2 MG/KG,. During the same period patient was treated with PACLITAXEL. Patient recovered.

Herceptin Side Effects Report #5097797-7
Herceptin side effect was reported by a Consumer or non-health professional from UNITED STATES on Jan 18, 2006. Female patient, 71 years of age, was diagnosed with breast cancer metastatic and was treated with Herceptin. After drug was administered, patient experienced the following side effects: bladder neoplasm, blister, disease progression, erythema, neck mass. Herceptin dosage: 2 MG/KG. During the same period patient was treated with VINORELBINE. Patient recovered.

Herceptin Side Effects Report #5232306-0
Herceptin side effect was reported by a Physician from SPAIN on Jan 19, 2007. Female patient, 65 years of age, was diagnosed with breast cancer metastatic and was treated with Herceptin. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood bilirubin increased, blood chloride decreased, disease progression, gamma-glutamyltransferase increased, metastases to bone, metastases to liver, metastases to lung. Herceptin dosage: 136 MG, 1/WEEK, INTRAVENOUS. During the same period patient was treated with PACLITAXEL, ATENOLOL, PANTOPRAZOLE, ACETYLCYSTEINE. Patient died on 01/07/2007.

Herceptin Side Effects Report #4875035-5
Herceptin side effect was reported by a Physician from JAPAN on Dec 01, 2005. Female patient, 62 years of age, was diagnosed with breast cancer metastatic and was treated with Herceptin. After drug was administered, patient experienced the following side effects: anaemia, anorexia, blood alkaline phosphatase increased, blood lactate dehydrogenase increased, blood potassium increased, blood urea increased, chest discomfort, disease progression, dizziness

. Herceptin dosage: 212 MG, INTRAVENOUS; SEE IMAGE. During the same period patient was treated with DOCETAXEL, VOLTAREN. Patient was hospitalized. Patient recovered.

Herceptin Side Effects Report #4932370-X
Herceptin side effect was reported by a Physician from SERBIA AND MONTENEGRO on Feb 27, 2006. Female patient, 61 years of age, was diagnosed with breast cancer metastatic and was treated with Herceptin. After drug was administered, patient experienced the following side effects: bronchopneumonia, disease progression, febrile neutropenia, malignant neoplasm progression, metastases to liver, pleural effusion. Herceptin dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, METHOTREXATE, FLUOROURACIL, VERAPAMIL. Patient was hospitalized. Patient died on 02/12/2006.

Herceptin Side Effects Report #5816817-2
Herceptin side effect was reported by a Physician from UNITED KINGDOM on July 08, 2008. Female patient, 60 years of age, was diagnosed with breast cancer metastatic and was treated with Herceptin. After drug was administered, patient experienced the following side effects: disease progression, vocal cord paralysis. Herceptin dosage: unknown. During the same period patient was treated with STEDIRIL, LEVOTHYROXINE, GINKOR, MOPRAL, LEGALON, ACTOS, DIAMICRON, NAVELBINE. Patient recovered.

Herceptin Side Effects Report #4932371-1
Herceptin side effect was reported by a Physician from YUGOSLAVIA on Feb 10, 2006. Female patient, 56 years of age, weighting 145.5 lb, was diagnosed with breast cancer metastatic and was treated with Herceptin. After drug was administered, patient experienced the following side effects: bronchopneumonia, disease progression, febrile neutropenia, malignant neoplasm progression, metastases to liver, pleural effusion. Herceptin dosage: unknown. During the same period patient was treated with METHOTREXATE, FLUOROURACIL, CYCLOPHOSPHAMIDE, VERAPAMIL. Patient was hospitalized. Patient died on 02/12/2006.

Herceptin Side Effects Report #5206124-3
Herceptin side effect was reported by a Physician from UNITED STATES on Jan 03, 2007. Female patient, 55 years of age, was diagnosed with breast cancer metastatic and was treated with Herceptin. After drug was administered, patient experienced the following side effects: disease progression, hyperkeratosis, malignant neoplasm progression, nail dystrophy, onycholysis, skin discolouration, skin exfoliation. Herceptin dosage: 2 MG/KG, 1/WEEK,. During the same period patient was treated with DOCETAXEL. Patient recovered.

Herceptin Side Effects Report #5633691-8
Herceptin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Feb 06, 2008. Female patient, 54 years of age, weighting 132.3 lb, was diagnosed with breast cancer metastatic and was treated with Herceptin. After drug was administered, patient experienced the following side effects: abdominal pain

, disease progression, gastrointestinal inflammation, loss of consciousness, malaise, nausea

, somnolence. Herceptin dosage: 240 MG, UNK. Patient died on 01/09/2008.

Herceptin Side Effects Report #5232462-4
Herceptin side effect was reported by a Physician from CROATIA (local name: Hrvatska) on Jan 23, 2007. Female patient, 52 years of age, was diagnosed with breast cancer metastatic and was treated with Herceptin. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood bilirubin increased, diarrhoea, disease progression, hepatic enzyme increased, pyrexia. Herceptin dosage: 2 MG/KG, 1/WEEK, INTRAVENOUS. During the same period patient was treated with LAPATINIB DITOSYLATE. Patient recovered.

Herceptin Side Effects Report #6134235-7
Herceptin side effect was reported by a Consumer or non-health professional from JAPAN on Mar 11, 2009. Female patient, 47 years of age, was diagnosed with breast cancer metastatic and was treated with Herceptin. After drug was administered, patient experienced the following side effects: disease progression, infusion related reaction, pancytopenia. Herceptin dosage: unknown. During the same period patient was treated with PACLITAXEL. Patient died.

Herceptin Side Effects Report #5463013-7
Herceptin side effect was reported by a Physician from UNITED KINGDOM on Sept 05, 2007. Female patient, 45 years of age, was diagnosed with breast cancer metastatic and was treated with Herceptin. After drug was administered, patient experienced the following side effects: coma hepatic, disease progression, hepatic failure. Herceptin dosage: unknown. Patient died on 08/01/2007.

Herceptin Side Effects Report #5225105-7
Herceptin side effect was reported by a Health Professional from UNITED STATES on Jan 23, 2007. Female patient was diagnosed with breast cancer metastatic and was treated with Herceptin. After drug was administered, patient experienced the following side effects: colorectal cancer

, disease progression. Herceptin dosage: unknown. During the same period patient was treated with TAXOTERE, NAVELBINE. Patient recovered.

Herceptin Side Effects Report #5614287-0
Herceptin side effect was reported by a Physician from UNITED KINGDOM on Jan 23, 2008. Female patient, weighting 172.0 lb, was diagnosed with breast cancer metastatic and was treated with Herceptin. After drug was administered, patient experienced the following side effects: disease progression, pneumonia primary atypical, pneumonitis. Herceptin dosage: 150 MG, 1/WEEK. During the same period patient was treated with TAXOTERE. Patient was hospitalized. Patient recovered.

Herceptin Side Effects Report #4906688-0
Herceptin side effect was reported by a Health Professional from UNITED STATES on Jan 25, 2006. Female patient was diagnosed with breast cancer metastatic and was treated with Herceptin. After drug was administered, patient experienced the following side effects: colorectal cancer

and was treated with Herceptin. After drug was administered, patient experienced the following side effects: blood ph increased, disease progression, respiratory failure. Herceptin dosage: 106 MG, 1/WEEK, INTRAVENOUS. During the same period patient was treated with TAXOTERE. Patient was hospitalized. Patient recovered.

Herceptin Side Effects Report #5158123-8
Herceptin side effect was reported by a Physician from JAPAN on Nov 01, 2006. Female patient, 50 years of age, was diagnosed with breast cancer

and was treated with Herceptin. After drug was administered, patient experienced the following side effects: alveolitis, blood ph increased, disease progression, dyspnoea, hypersensitivity, lung disorder, po2 increased. Herceptin dosage: 106 MG, 1 WEEK, INTRAVENOUS. During the same period patient was treated with TAXOTERE, CISPLATIN, CYCLOPHOSPHAMIDE, EPIRUBICIN, ETOPOSIDE, FLUOROURACIL. Patient was hospitalized. Patient recovered.

Herceptin Side Effects Report #5102997-3
Herceptin side effect was reported by a Physician from CHINA on Aug 24, 2006. Female patient, 38 years of age, was diagnosed with breast cancer

and was treated with Herceptin. After drug was administered, patient experienced the following side effects: chest pain

, condition aggravated, cough, disease progression, dyspnoea, heart rate increased. Herceptin dosage: 4 MG/KG, INTRAVENOUS. During the same period patient was treated with PACLITAXEL. Patient was hospitalized. Patient recovered.

Herceptin Side Effects Report #5129893-X
Herceptin side effect was reported by a Physician from CHINA on Sept 29, 2006. Female patient, 38 years of age, was diagnosed with breast cancer

and was treated with Herceptin. After drug was administered, patient experienced the following side effects: chest pain

, cough, disease progression, dyspnoea, heart rate increased. Herceptin dosage: 4 MG/KG, INTRAVENOUS. During the same period patient was treated with PACLITAXEL. Patient was hospitalized. Patient recovered.

Herceptin Side Effects Report #5739595-4
Herceptin side effect was reported by a Pharmacist from UNITED STATES on May 08, 2008. Male patient was diagnosed with breast cancer

and was treated with Herceptin. After drug was administered, patient experienced the following side effects: disease progression, ejection fraction decreased. Herceptin dosage: 650 MG, SINGLE. During the same period patient was treated with TAXOTERE, CARBOPLATIN, ARIMIDEX. Patient recovered.

Herceptin Side Effects Report #6016842-5
Herceptin side effect was reported by a Physician from FRANCE on Dec 09, 2008. Female patient was diagnosed with breast cancer

and was treated with Herceptin. After drug was administered, patient experienced the following side effects: disease progression, mitral valve incompetence. Herceptin dosage: unknown. Patient recovered.

Herceptin Side Effects Report #4779073-2
Herceptin side effect was reported by a Physician from FRANCE on Sept 05, 2005. Male patient, 59 years of age, was diagnosed with bladder cancer

and was treated with Herceptin. After drug was administered, patient experienced the following side effects: aplasia, disease progression, haematuria, thrombocytopenia. Herceptin dosage: 400 MG, Q3W, INTRAVENOUS. During the same period patient was treated with CARBOPLATIN, GEMCITABINE. Patient died on 07/29/2004.

Herceptin Side Effects Report #5099008-5
Herceptin side effect was reported by a Physician from UNITED STATES on May 03, 2006. Female patient, 66 years of age, was treated with Herceptin. After drug was administered, patient experienced the following side effects: disease progression. Herceptin dosage: unknown. Patient recovered.

Herceptin Side Effects Report #4591282-4
Herceptin side effect was reported by a Consumer or non-health professional from on Feb 24, 2005. Female patient, 58 years of age, weighting 242.5 lb, was treated with Herceptin. After drug was administered, patient experienced the following side effects: cardio-respiratory arrest, coma, disease progression, fatigue. Herceptin dosage: 4 MG/KG= 220 MG IV. Patient died.

Herceptin and disease progression

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Herceptin and disease progression Patient Reports February 11, 2012

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