Gliadel and intracranial hypotension Patient Reports February 11, 2012

Gliadel Side Effects Report #5982901-6
Gliadel side effect was reported by a Health Professional from UNITED STATES on July 08, 2008. Male patient, 63 years of age, was diagnosed with metastases to central nervous system and was treated with Gliadel. After drug was administered, patient experienced the following side effects: intracranial hypotension, off label use, postoperative wound infection. Gliadel dosage: unknown. During the same period patient was treated with AVODART, TAMSULOSIN, REMERON, SPIRIVA. Patient was hospitalized. Patient recovered.

Gliadel Side Effects Report #5236583-1
Gliadel side effect was reported by a Consumer or non-health professional from UNITED STATES on Jan 24, 2007. Female patient, 49 years of age, weighting 125.2 lb, was diagnosed with metastases to central nervous system and was treated with Gliadel. After drug was administered, patient experienced the following side effects: bacterial infection , brain abscess, erythema, extradural abscess, haemoglobin decreased, intracranial hypotension, platelet count increased, post procedural complication, postoperative wound infection. Gliadel dosage: unknown. During the same period patient was treated with TYLENOL, GABAPENTIN, ESZOPICLONE, METHADONE, PAXIL, SENOKOT, TOLTERODINE, LINEZOLID. Patient was hospitalized. Patient recovered.

Gliadel Side Effects Report #5526997-4
Gliadel side effect was reported by a Physician from UNITED STATES on Feb 15, 2007. Female patient was diagnosed with malignant glioma, recurrent cancer and was treated with Gliadel. After drug was administered, patient experienced the following side effects: ataxia , cerebral haemorrhage, confusional state, convulsion, headache , infection , intracranial hypotension, intracranial pressure increased. Gliadel dosage: unknown. Patient recovered.

Gliadel Side Effects Report #5788147-9
Gliadel side effect was reported by a Consumer or non-health professional from UNITED STATES on June 12, 2008. Female patient was diagnosed with malignant glioma and was treated with Gliadel. After drug was administered, patient experienced the following side effects: arachnoiditis, central nervous system infection, extradural haematoma, hydrocephalus , hyponatraemia, intracranial hypotension, meningitis , postoperative wound infection, pyrexia. Gliadel dosage: unknown. Patient recovered.


Gliadel Side Effects Report #5982934-X
Gliadel side effect was reported by a Health Professional from UNITED STATES on July 10, 2008. Female patient was diagnosed with malignant glioma and was treated with Gliadel. After drug was administered, patient experienced the following side effects: brain oedema, cerebral cyst, convulsion, deep vein thrombosis , impaired healing, implant site reaction, intracranial hypotension, meningitis . Gliadel dosage: unknown. Patient was hospitalized. Patient recovered.

Gliadel Side Effects Report #5265057-7
Gliadel side effect was reported by a Health Professional from UNITED STATES on Aug 14, 2006. Female patient, 58 years of age, weighting 169.8 lb, was diagnosed with glioblastoma multiforme and was treated with Gliadel. After drug was administered, patient experienced the following side effects: deep vein thrombosis , extradural haematoma, intracranial hypotension, wound , wound infection. Gliadel dosage: unknown. During the same period patient was treated with LEXAPRO, PROTONIX, CHLORIDE, DECADRON, TYLENOL, ATIVAN, VALPROIC ACID. Patient was hospitalized. Patient recovered.

Gliadel Side Effects Report #5526707-0
Gliadel side effect was reported by a Health Professional from UNITED STATES on Dec 07, 2006. Female patient, 58 years of age, weighting 169.8 lb, was diagnosed with glioblastoma multiforme and was treated with Gliadel. After drug was administered, patient experienced the following side effects: disease progression, intracranial hypotension, renal failure acute, renal tubular necrosis, wound infection staphylococcal. Gliadel dosage: unknown. During the same period patient was treated with DECADRON, VALPROIC ACID, PROTONIX, LEXAPRO, SENOKOT, CHLORIDE, TYLENOL. Patient was hospitalized. Patient died on 12/03/2006.

Gliadel Side Effects Report #5526942-1
Gliadel side effect was reported by a Consumer or non-health professional from UNITED STATES on Oct 17, 2006. Female patient, 58 years of age, weighting 169.8 lb, was diagnosed with glioblastoma multiforme and was treated with Gliadel. After drug was administered, patient experienced the following side effects: deep vein thrombosis , extradural haematoma, intracranial hypotension, wound infection. Gliadel dosage: unknown. During the same period patient was treated with LEXAPRO, PROTONIX, CHLORIDE, DECADRON, TYLENOL, ATIVAN, VALPROIC ACID. Patient was hospitalized. Patient recovered.

Gliadel Side Effects Report #5264625-6
Gliadel side effect was reported by a Consumer or non-health professional from UNITED STATES on Feb 27, 2006. Male patient, 47 years of age, weighting 221.1 lb, was diagnosed with glioblastoma multiforme and was treated with Gliadel. After drug was administered, patient experienced the following side effects: hallucination, intracranial hypotension, mental status changes, pneumonia , venous thrombosis limb, wound infection staphylococcal. Gliadel dosage: 61.6 MG;X1;ICER. During the same period patient was treated with DECADRON, ZANTAC, DILANTIN, OXYCODONE. Patient was hospitalized. Patient recovered.


Gliadel Side Effects Report #4852568-9
Gliadel side effect was reported by a Health Professional from UNITED STATES on Feb 15, 2005. Female patient, 40 years of age, weighting 216.1 lb, was diagnosed with glioblastoma multiforme and was treated with Gliadel. After drug was administered, patient experienced the following side effects: intracranial hypotension. Gliadel dosage: 7.7MG/WAFER-MAX OF 8. During the same period patient was treated with DILANTIN, ASACOL, DECADRON, IMODIUM, PROTONIX. Patient recovered.

Gliadel Side Effects Report #5619126-X
Gliadel side effect was reported by a Physician from UNITED STATES on Jan 22, 2008. Male patient, 39 years of age, was diagnosed with glioblastoma multiforme and was treated with Gliadel. After drug was administered, patient experienced the following side effects: application site discharge, application site inflammation, brain mass, intracranial hypotension, leukocytosis, post procedural complication, purulence, pyrexia, surgical procedure repeated. Gliadel dosage: unknown. During the same period patient was treated with DILANTIN, KEPPRA. Patient was hospitalized. Patient recovered.

Gliadel Side Effects Report #5637205-8
Gliadel side effect was reported by a Health Professional from UNITED STATES on Feb 20, 2008. Male patient, 39 years of age, weighting 176.1 lb, was diagnosed with glioblastoma multiforme and was treated with Gliadel. After drug was administered, patient experienced the following side effects: central nervous system necrosis, intracranial hypotension, post procedural swelling, postoperative fever. Gliadel dosage: 61.6 MG PER WAFER ONE TIME IMPLANT. Patient recovered.

Gliadel Side Effects Report #4852562-8
Gliadel side effect was reported by a Physician from UNITED STATES on July 26, 2005. Male patient, 35 years of age, weighting 180.0 lb, was diagnosed with glioblastoma multiforme and was treated with Gliadel. After drug was administered, patient experienced the following side effects: intracranial hypotension, pyrexia. Gliadel dosage: unknown. Patient recovered.

Gliadel Side Effects Report #5082202-7
Gliadel side effect was reported by a Health Professional from UNITED STATES on Aug 15, 2006. Female patient, weighting 169.8 lb, was diagnosed with glioblastoma multiforme and was treated with Gliadel. After drug was administered, patient experienced the following side effects: extradural haematoma, glioblastoma multiforme, haemoglobin abnormal, headache , intracranial hypotension, malignant neoplasm progression, platelet count abnormal, postoperative infection, seroma. Gliadel dosage: 7.7 MG PER WAFER ONCE IV. During the same period patient was treated with DILANTIN, KEPPRA, ATIVAN, CELEXA, PEPCID, SENOKOT, COLACE. Patient was hospitalized. Patient recovered.


Gliadel Side Effects Report #5130261-5
Gliadel side effect was reported by a Health Professional from UNITED STATES on Oct 18, 2006. Female patient, weighting 169.8 lb, was diagnosed with glioblastoma multiforme and was treated with Gliadel. After drug was administered, patient experienced the following side effects: brain scan abnormal, csf test abnormal, extradural haematoma, haemoglobin abnormal, headache , incision site complication, infection , intracranial hypotension, lethargy. Gliadel dosage: 7.7 MG PER WAFER ONCE IV. During the same period patient was treated with LEXAPRO, PROTONIX, CHLORIDE, DECADRON, TYLENOL, ATIVAN, VALPROIC ACID. Patient was hospitalized. Patient recovered.

Gliadel Side Effects Report #5130262-7
Gliadel side effect was reported by a Health Professional from UNITED STATES on Oct 18, 2006. Female patient, weighting 169.8 lb, was diagnosed with glioblastoma multiforme and was treated with Gliadel. After drug was administered, patient experienced the following side effects: deep vein thrombosis , haemoglobin abnormal, hyponatraemia, incision site complication, intracranial hypotension, pyrexia, venous thrombosis, wound complication. Gliadel dosage: 7.L7 MG PER WAFER ONCE IV. During the same period patient was treated with LEXAPRO, PROTONIX, CHLORIDE, DECADRON, TYLENOL, ATIVAN, VALPROIC ACID. Patient was hospitalized. Patient recovered.

Gliadel Side Effects Report #5173740-7
Gliadel side effect was reported by a Health Professional from UNITED STATES on Dec 08, 2006. Female patient, weighting 169.8 lb, was diagnosed with glioblastoma multiforme and was treated with Gliadel. After drug was administered, patient experienced the following side effects: central nervous system lesion, cerebral haemorrhage, diarrhoea, disorientation, gastroenteritis viral, impaired healing, infection , intracranial hypotension, lethargy. Gliadel dosage: 7.7 MG PER WAFER ONCE IV. During the same period patient was treated with DECADRON, VALPROIC ACID, PROTONIX, LEXAPRO, SENOKOT, CHLORIDE, TYLENOL. Patient was hospitalized. Patient recovered.

Gliadel Side Effects Report #5484455-X
Gliadel side effect was reported by a Physician from UNITED STATES on Oct 03, 2007. Female patient was diagnosed with glioblastoma multiforme and was treated with Gliadel. After drug was administered, patient experienced the following side effects: arachnoiditis, cerebral hygroma, hydrocephalus , hyponatraemia, intracranial hypotension, meningitis , postoperative wound infection, pyrexia. Gliadel dosage: unknown. Patient recovered.

Gliadel Side Effects Report #5490043-1
Gliadel side effect was reported by a Physician from UNITED STATES on June 27, 2007. Female patient was diagnosed with glioblastoma multiforme and was treated with Gliadel. After drug was administered, patient experienced the following side effects: arachnoiditis, cerebral hygroma, hydrocephalus , hyponatraemia, intracranial hypotension, meningitis , postoperative wound infection. Gliadel dosage: unknown. Patient recovered.


Gliadel Side Effects Report #6070136-0
Gliadel side effect was reported by a Consumer or non-health professional from UNITED STATES on Feb 06, 2009. Female patient, weighting 134.5 lb, was diagnosed with brain neoplasm and was treated with Gliadel. After drug was administered, patient experienced the following side effects: alpha haemolytic streptococcal infection, blood calcium decreased, blood magnesium decreased, blood phosphorus decreased, blood potassium decreased, csf culture positive, intracranial hypotension, soft tissue necrosis, subdural hygroma. Gliadel dosage: unknown. Patient was hospitalized. Patient recovered.