Gliadel and disease progression Patient Reports February 11, 2012

Gliadel Side Effects Report #5982881-3
Gliadel side effect was reported by a Physician from UNITED STATES on Dec 05, 2008. Female patient, 46 years of age, was diagnosed with metastases to spine and was treated with Gliadel. After drug was administered, patient experienced the following side effects: disease progression, off label use. Gliadel dosage: 15.4 MG;X1;ICAV. Patient died.

Gliadel Side Effects Report #5982896-5
Gliadel side effect was reported by a Physician from UNITED STATES on Dec 05, 2006. Male patient, 38 years of age, was diagnosed with metastases to spine and was treated with Gliadel. After drug was administered, patient experienced the following side effects: disease progression, off label use. Gliadel dosage: 23.1 MG;X1;ICAV. Patient died.

Gliadel Side Effects Report #5475337-8
Gliadel side effect was reported by a Physician from UNITED STATES on Apr 18, 2007. Female patient was diagnosed with malignant glioma and was treated with Gliadel. After drug was administered, patient experienced the following side effects: disease progression, haematotoxicity, neurotoxicity, neutropenia, pancytopenia, thrombocytopenia, wound infection. Gliadel dosage: unknown. During the same period patient was treated with TEMOZOLOMIDE. Patient recovered.

Gliadel Side Effects Report #5527012-9
Gliadel side effect was reported by a Health Professional from UNITED STATES on Oct 01, 2006. Female patient, 71 years of age, was diagnosed with glioblastoma multiforme and was treated with Gliadel. After drug was administered, patient experienced the following side effects: disease progression. Gliadel dosage: 61.6 MG;X1;ICER. Patient died.


Gliadel Side Effects Report #5526963-9
Gliadel side effect was reported by a Health Professional from UNITED STATES on Oct 17, 2006. Male patient, 69 years of age, weighting 142.2 lb, was diagnosed with glioblastoma multiforme and was treated with Gliadel. After drug was administered, patient experienced the following side effects: disease progression. Gliadel dosage: unknown. During the same period patient was treated with CARBATROL, ZANTAC, HYDROCHLOROTHIAZIDE, CHLORIDE, DECADRON. Patient died on 09/22/2006.

Gliadel Side Effects Report #5526707-0
Gliadel side effect was reported by a Health Professional from UNITED STATES on Dec 07, 2006. Female patient, 58 years of age, weighting 169.8 lb, was diagnosed with glioblastoma multiforme and was treated with Gliadel. After drug was administered, patient experienced the following side effects: disease progression, intracranial hypotension, renal failure acute, renal tubular necrosis, wound infection staphylococcal. Gliadel dosage: unknown. During the same period patient was treated with DECADRON, VALPROIC ACID, PROTONIX, LEXAPRO, SENOKOT, CHLORIDE, TYLENOL. Patient was hospitalized. Patient died on 12/03/2006.

Gliadel Side Effects Report #5264617-7
Gliadel side effect was reported by a Physician from SPAIN on Feb 14, 2006. Female patient, 54 years of age, was diagnosed with glioblastoma multiforme and was treated with Gliadel. After drug was administered, patient experienced the following side effects: brain oedema, disease progression. Gliadel dosage: 61.6 MG;X1;ICERE. Patient was hospitalized. Patient died on 02/21/2006.

Gliadel Side Effects Report #5066522-8
Gliadel side effect was reported by a Health Professional from UNITED STATES on July 31, 2006. Male patient, weighting 175.7 lb, was diagnosed with glioblastoma multiforme and was treated with Gliadel. After drug was administered, patient experienced the following side effects: convulsion, disease progression, fall , head injury, hemiparesis, hypoaesthesia, partial seizures. Gliadel dosage: 7.7 MG PER WAFER ONCE IV. During the same period patient was treated with DILANTIN, KEPPRA, SENOKOT, CITALOPRA, INNOHEP, DEXAMETHASONE, CENTRUM SILVER. Patient was hospitalized. Patient recovered.

Gliadel Side Effects Report #5475338-X
Gliadel side effect was reported by a Physician from UNITED STATES on Nov 16, 2006. Female patient was diagnosed with glioblastoma multiforme and was treated with Gliadel. After drug was administered, patient experienced the following side effects: brain abscess, cerebral haemorrhage, constipation , deep vein thrombosis , disease progression, embolism venous, fall , fatigue, nausea . Gliadel dosage: unknown. During the same period patient was treated with TEMOZOLOMIDE. Patient died.


Gliadel Side Effects Report #5475339-1
Gliadel side effect was reported by a Physician from UNITED STATES on Dec 08, 2006. Female patient was diagnosed with glioblastoma multiforme and was treated with Gliadel. After drug was administered, patient experienced the following side effects: convulsion, disease progression, necrosis, pulmonary embolism , radiation injury, recurrent cancer, tumour necrosis. Gliadel dosage: unknown. Patient died.

Gliadel Side Effects Report #5918292-6
Gliadel side effect was reported by a Physician from UNITED STATES on Sept 23, 2008. Female patient was diagnosed with glioblastoma multiforme and was treated with Gliadel. After drug was administered, patient experienced the following side effects: aplastic anaemia, brain abscess, cerebral haemorrhage, constipation , deep vein thrombosis , disease progression, embolism venous, fall , fatigue. Gliadel dosage: unknown. During the same period patient was treated with TEMOZOLOMIDE. Patient died.

Gliadel Side Effects Report #5982825-4
Gliadel side effect was reported by a Physician from UNITED STATES on Oct 01, 2007. Female patient was diagnosed with glioblastoma multiforme and was treated with Gliadel. After drug was administered, patient experienced the following side effects: disease progression, implant site necrosis, postoperative wound complication. Gliadel dosage: unknown. Patient died.

Gliadel Side Effects Report #5982908-9
Gliadel side effect was reported by a Consumer or non-health professional from UNITED STATES on June 27, 2007. Female patient was diagnosed with glioblastoma multiforme and was treated with Gliadel. After drug was administered, patient experienced the following side effects: brain oedema, disease progression, encephalitis , implant site necrosis, postoperative wound infection, psychotic disorder . Gliadel dosage: unknown. During the same period patient was treated with TEMOZOLOMIDE. Patient died.

Gliadel Side Effects Report #4751354-8
Gliadel side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 23, 2005. Female patient, weighting 119.5 lb, was diagnosed with glioblastoma multiforme and was treated with Gliadel. After drug was administered, patient experienced the following side effects: back pain , disease progression, metastases to spine. Gliadel dosage: 7.7 MG PER WAFER - MAX OF 8. Patient died on 08/04/2005.


Gliadel Side Effects Report #5001726-1
Gliadel side effect was reported by a Consumer or non-health professional from UNITED STATES on May 12, 2006. Male patient, weighting 221.1 lb, was diagnosed with glioblastoma multiforme and was treated with Gliadel. After drug was administered, patient experienced the following side effects: cough, disease progression, hallucination, mental status changes, pneumonia , staphylococcal infection , unevaluable event, venoocclusive disease. Gliadel dosage: 7.7 MG PER WAFER - MAX OF 8. During the same period patient was treated with OXYCONTIN, DEXAMETHASONE, DEPAKENE, RISPERDAL, KLONOPIN, THIAMINE, FOLIC ACID. Patient was hospitalized. Patient recovered.

Gliadel Side Effects Report #5526703-3
Gliadel side effect was reported by a Health Professional from UNITED STATES on Oct 13, 2006. Female patient, 47 years of age, weighting 183.0 lb, was diagnosed with brain neoplasm and was treated with Gliadel. After drug was administered, patient experienced the following side effects: disease progression. Gliadel dosage: unknown. During the same period patient was treated with TEMODAR, LISINOPRIL, DIFLUCAN, KEPPRA, DECADRON. Patient was hospitalized. Patient recovered.

Gliadel Side Effects Report #4726172-7
Gliadel side effect was reported by a Physician from FRANCE on July 14, 2005. Male patient, 55 years of age, was treated with Gliadel. After drug was administered, patient experienced the following side effects: disease progression. Gliadel dosage: 7.7MG/WAFER; 3 WAFERS. Patient was hospitalized. Patient recovered.