Gemtuzumab and blood bilirubin increased Patient Reports February 13, 2012

Gemtuzumab Side Effects Report #5097855-7
Gemtuzumab side effect was reported by a Consumer or non-health professional from GERMANY on Aug 25, 2006. Female patient, 66 years of age, was diagnosed with acute myeloid leukaemia and was treated with Gemtuzumab. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood bilirubin increased, blood calcium decreased, blood chloride increased, blood fibrinogen increased, blood lactate dehydrogenase increased, blood sodium increased. Gemtuzumab dosage: 10.5 MG INTRAVENOUS. During the same period patient was treated with GEMTUZUMAB OZOGAMICIN, CYTARABINE. Patient was hospitalized. Patient died.

Gemtuzumab Side Effects Report #5097882-X
Gemtuzumab side effect was reported by a Consumer or non-health professional from GERMANY on Aug 25, 2006. Female patient, 66 years of age, was diagnosed with acute myeloid leukaemia and was treated with Gemtuzumab. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood bilirubin increased, blood calcium decreased, blood chloride increased, blood fibrinogen increased, blood lactate dehydrogenase increased, blood sodium increased. Gemtuzumab dosage: 10.5 MG INTRAVENOUS. During the same period patient was treated with GEMTUZUMAB OZOGAMICIN, CYTARABINE. Patient died.

Gemtuzumab Side Effects Report #4721952-6
Gemtuzumab side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on July 08, 2005. Female patient, 59 years of age, was diagnosed with acute myeloid leukaemia and was treated with Gemtuzumab. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, blood alkaline phosphatase increased, blood bilirubin increased, bone marrow depression, hepatotoxicity. Gemtuzumab dosage: unknown. During the same period patient was treated with CYTARABINE, FLUDARABINE, GRANULOCYTE COLONY STIMULATING FACTOR, IDARUBICIN, NOVANTRONE. Patient recovered.

Gemtuzumab Side Effects Report #5959732-6
Gemtuzumab side effect was reported by a Pharmacist from UNITED STATES on Nov 19, 2008. Female patient, 55 years of age, weighting 185.2 lb, was diagnosed with acute myeloid leukaemia and was treated with Gemtuzumab. After drug was administered, patient experienced the following side effects: abdominal distension, abdominal pain , alanine aminotransferase increased, aspartate aminotransferase increased, blood bilirubin increased, fatigue, international normalised ratio increased, pyrexia. Gemtuzumab dosage: 17MG IV X 1. Patient was hospitalized. Patient recovered.


Gemtuzumab Side Effects Report #5488607-4
Gemtuzumab side effect was reported by a Physician from UNITED KINGDOM on Oct 16, 2007. Male patient, weighting 191.6 lb, was diagnosed with acute myeloid leukaemia, prophylaxis and was treated with Gemtuzumab. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, blood bilirubin increased, c-reactive protein increased, gamma-glutamyltransferase increased, venoocclusive liver disease. Gemtuzumab dosage: 5 MG EVERY 1 TOT. During the same period patient was treated with ETOPOSIDE, CYTARABINE, ATORVASTATIN CALCIUM, CIPROFLOXACIN, METRONIDAZOLE, GENTAMICIN. Patient recovered.

Gemtuzumab Side Effects Report #5807571-9
Gemtuzumab side effect was reported by a Physician from FRANCE on July 04, 2008. Male patient was diagnosed with acute myeloid leukaemia and was treated with Gemtuzumab. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood bilirubin increased, cholelithiasis, gamma-glutamyltransferase increased, jaundice . Gemtuzumab dosage: 5 MG EVERY 1 CYC. During the same period patient was treated with EFFEXOR, ARACYTINE, BACTRIM, TIENAM, DAUNORUBICIN, PANTOPRAZOLE, TAHOR. Patient was hospitalized. Patient recovered.

Gemtuzumab Side Effects Report #5950509-4
Gemtuzumab side effect was reported by a Physician from FRANCE on Nov 07, 2008. Male patient was diagnosed with acute myeloid leukaemia and was treated with Gemtuzumab. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood bilirubin increased, cholelithiasis, gamma-glutamyltransferase increased, jaundice . Gemtuzumab dosage: 5 MG EVERY 1 CYC. During the same period patient was treated with EFFEXOR, CYTARABINE, BACTRIM, TIENAM, DAUNORUBICIN, PANTOPRAZOLE, TAHOR. Patient was hospitalized. Patient recovered.

Gemtuzumab Side Effects Report #4891991-3
Gemtuzumab side effect was reported by a Pharmacist from UNITED STATES on Jan 24, 2006. Male patient, child 10 years of age, weighting 14.33 lb, was diagnosed with acute leukaemia and was treated with Gemtuzumab. After drug was administered, patient experienced the following side effects: blood bilirubin increased, fluid overload, hepatic function abnormal, sepsis , transaminases increased, venoocclusive liver disease, weight increased. Gemtuzumab dosage: 6 MG /M2 IV (1 DOSE). During the same period patient was treated with ALEMTUZUMAB. Patient was hospitalized. Patient recovered.

Gemtuzumab Side Effects Report #5089444-5
Gemtuzumab side effect was reported by a Consumer or non-health professional from NETHERLANDS on Aug 10, 2006. Female patient, 62 years of age, was treated with Gemtuzumab. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, ascites, aspartate aminotransferase increased, atrial fibrillation , blood bilirubin increased, candidiasis, fluid retention, hepatic function abnormal. Gemtuzumab dosage: 5.2 MG. During the same period patient was treated with CYTARABINE, ETOPOSIDE, IDARUBICIN, SULFAMETHOXAZOLE, COLISTIN. Patient died.


Gemtuzumab Side Effects Report #5145348-0
Gemtuzumab side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Oct 24, 2006. Male patient, 62 years of age, was treated with Gemtuzumab. After drug was administered, patient experienced the following side effects: blood albumin increased, blood bilirubin increased, blood phosphorus increased, blood sodium increased, blood urea increased, blood uric acid decreased, c-reactive protein increased, haematocrit decreased, haemoglobin decreased. Gemtuzumab dosage: unknown. Patient was hospitalized. Patient died.

Gemtuzumab Side Effects Report #6119966-7
Gemtuzumab side effect was reported by a Physician from UNITED KINGDOM on Mar 10, 2009. Female patient was treated with Gemtuzumab. After drug was administered, patient experienced the following side effects: aspartate aminotransferase increased, blood alkaline phosphatase increased, blood bilirubin increased, protein total increased. Gemtuzumab dosage: 4.65 MG EVERY 1 TOT. Patient recovered.