Gefitinib and malignant neoplasm progression Patient Reports February 12, 2012

Gefitinib Side Effects Report #4569569-0
Gefitinib side effect was reported by a Consumer or non-health professional from on Jan 24, 2005. Female patient, 60 years of age, was diagnosed with non-small cell lung cancer and was treated with Gefitinib. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, interstitial lung disease, lung infection, lymphangiosis carcinomatosa, malignant neoplasm progression, respiratory distress, respiratory failure. Gefitinib dosage: 250 MG DAILY. During the same period patient was treated with CARBOPLATIN, GEMCITABINE. Patient died.

Gefitinib Side Effects Report #4928992-2
Gefitinib side effect was reported by a Physician from UNITED KINGDOM on July 20, 2005. Male patient, weighting 133.2 lb, was diagnosed with non-small cell lung cancer, analgesic effect, depression , insomnia, pain , muscle spasms and was treated with Gefitinib. After drug was administered, patient experienced the following side effects: anaemia, diarrhoea, intestinal obstruction, liver function test abnormal, malignant neoplasm progression, non-small cell lung cancer, overgrowth bacterial, pain , pancreatic insufficiency. Gefitinib dosage: unknown. During the same period patient was treated with GABAPENTIN, ACETAMINOPHEN, CARBAMAZEPINE, VENLAFAXINE, CLONAZEPAM, HALOPERIDOL, BUSCOPAN. Patient was hospitalized. Patient recovered.

Gefitinib Side Effects Report #4941031-2
Gefitinib side effect was reported by a Physician from UNITED KINGDOM on July 20, 2005. Male patient, weighting 133.2 lb, was diagnosed with non-small cell lung cancer, analgesic effect, depression , insomnia, pain , muscle spasms and was treated with Gefitinib. After drug was administered, patient experienced the following side effects: anaemia, diarrhoea, intestinal obstruction, liver function test abnormal, malignant neoplasm progression, non-small cell lung cancer, oral intake reduced, overgrowth bacterial, pain . Gefitinib dosage: unknown. During the same period patient was treated with GABAPENTIN, ACETAMINOPHEN, CARBAMAZEPINE, VENLAFAXINE, CLONAZEPAM, HALOPERIDOL, BUSCOPAN. Patient was hospitalized. Patient recovered.

Gefitinib Side Effects Report #4590448-7
Gefitinib side effect was reported by a Health Professional from on Feb 18, 2005. Female patient, weighting 129.0 lb, was diagnosed with glioblastoma multiforme and was treated with Gefitinib. After drug was administered, patient experienced the following side effects: brain oedema, computerised tomogram abnormal, electroencephalogram abnormal, facial palsy, fatigue, grand mal convulsion, infarction, malignant neoplasm progression, nervous system disorder. Gefitinib dosage: 750 MG DAILY PO. During the same period patient was treated with RAPAMUNE, SYNTHROID, RITALIN, COREG, CALTRATE, TRICOR, DECADRON, RANITIDINE. Patient was hospitalized. Patient recovered.


Gefitinib Side Effects Report #4609585-3
Gefitinib side effect was reported by a Physician from on Mar 14, 2005. Male patient, weighting 286.2 lb, was diagnosed with glioblastoma multiforme and was treated with Gefitinib. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, asthenia, bedridden, clostridium colitis, grand mal convulsion, hemiparesis, malignant neoplasm progression, pneumonia aspiration, pulmonary embolism . Gefitinib dosage: 500 MG PO QD. During the same period patient was treated with RAPAMUNE. Patient was hospitalized. Patient recovered.