Gefitinib and diarrhoea Patient Reports February 12, 2012

Gefitinib Side Effects Report #4600856-3
Gefitinib side effect was reported by a Physician from on Feb 21, 2005. Female patient, 70 years of age, was diagnosed with non-small cell lung cancer and was treated with Gefitinib. After drug was administered, patient experienced the following side effects: diarrhoea, dyspnoea, feeling hot, haemoglobin decreased, influenza like illness, oral pain, pulmonary mass, pulmonary toxicity, swelling face. Gefitinib dosage: 250 MG QD PO. During the same period patient was treated with RANITIDINE, MELOXICAM, BENDROFLUAZIDE. Patient recovered.

Gefitinib Side Effects Report #4640056-4
Gefitinib side effect was reported by a Physician from on Mar 30, 2005. Female patient, 70 years of age, was diagnosed with non-small cell lung cancer and was treated with Gefitinib. After drug was administered, patient experienced the following side effects: asthenia, diarrhoea, dyspnoea, feeling hot, haemoglobin decreased, influenza like illness, malaise, oral pain, pulmonary mass. Gefitinib dosage: 250 MG QD PO. During the same period patient was treated with RANITIDINE, MELOXICAM, BENDROFLUAZIDE. Patient recovered.

Gefitinib Side Effects Report #4851821-2
Gefitinib side effect was reported by a Health Professional from CANADA on Nov 30, 2005. Female patient, 57 years of age, was diagnosed with non-small cell lung cancer, pruritus, abdominal discomfort and was treated with Gefitinib. After drug was administered, patient experienced the following side effects: diarrhoea, dyspepsia, hepatic enzyme increased, hepatic fibrosis, hepatic necrosis, hepatitis , hepatocellular damage, rash pruritic. Gefitinib dosage: unknown. During the same period patient was treated with CHLORPHENIRAMINE MALEATE, FAMOTIDINE, ATENOLOL, HYDROCHLOROTHIAZIDE. Patient recovered.

Gefitinib Side Effects Report #4957592-3
Gefitinib side effect was reported by a Health Professional from CANADA on Nov 30, 2005. Female patient, 57 years of age, was diagnosed with non-small cell lung cancer, pruritus, abdominal discomfort and was treated with Gefitinib. After drug was administered, patient experienced the following side effects: diarrhoea, dyspepsia, hepatic enzyme increased, hepatic fibrosis, hepatic necrosis, hepatitis , rash pruritic. Gefitinib dosage: unknown. During the same period patient was treated with CHLORPHENIRAMINE MALEATE, FAMOTIDINE, ATENOLOL, HYDROCHLOROTHIAZIDE. Patient recovered.


Gefitinib Side Effects Report #4920025-7
Gefitinib side effect was reported by a Physician from UNITED KINGDOM on July 20, 2005. Male patient, weighting 133.2 lb, was diagnosed with non-small cell lung cancer, analgesic effect, depression , insomnia, pain , muscle spasms and was treated with Gefitinib. After drug was administered, patient experienced the following side effects: anaemia, diarrhoea, disease progression, intestinal obstruction, liver function test abnormal, oral intake reduced, pain , renal failure, somnolence. Gefitinib dosage: unknown. During the same period patient was treated with GABAPENTIN, ACETAMINOPHEN, CARBAMAZEPINE, VENLAFAXINE, CLONAZEPAM, HALOPERIDOL, BUSCOPAN. Patient was hospitalized. Patient recovered.

Gefitinib Side Effects Report #4921522-0
Gefitinib side effect was reported by a Health Professional from UNITED STATES on Feb 22, 2006. Male patient was diagnosed with non-small cell lung cancer and was treated with Gefitinib. After drug was administered, patient experienced the following side effects: diarrhoea, haemothorax, pleural effusion, pulmonary toxicity, skin disorder. Gefitinib dosage: unknown. During the same period patient was treated with ERLOTINIB, CARBO. Patient was hospitalized and became disabled. Patient died on 02/15/2006.

Gefitinib Side Effects Report #4928992-2
Gefitinib side effect was reported by a Physician from UNITED KINGDOM on July 20, 2005. Male patient, weighting 133.2 lb, was diagnosed with non-small cell lung cancer, analgesic effect, depression , insomnia, pain , muscle spasms and was treated with Gefitinib. After drug was administered, patient experienced the following side effects: anaemia, diarrhoea, intestinal obstruction, liver function test abnormal, malignant neoplasm progression, non-small cell lung cancer, overgrowth bacterial, pain , pancreatic insufficiency. Gefitinib dosage: unknown. During the same period patient was treated with GABAPENTIN, ACETAMINOPHEN, CARBAMAZEPINE, VENLAFAXINE, CLONAZEPAM, HALOPERIDOL, BUSCOPAN. Patient was hospitalized. Patient recovered.

Gefitinib Side Effects Report #4941031-2
Gefitinib side effect was reported by a Physician from UNITED KINGDOM on July 20, 2005. Male patient, weighting 133.2 lb, was diagnosed with non-small cell lung cancer, analgesic effect, depression , insomnia, pain , muscle spasms and was treated with Gefitinib. After drug was administered, patient experienced the following side effects: anaemia, diarrhoea, intestinal obstruction, liver function test abnormal, malignant neoplasm progression, non-small cell lung cancer, oral intake reduced, overgrowth bacterial, pain . Gefitinib dosage: unknown. During the same period patient was treated with GABAPENTIN, ACETAMINOPHEN, CARBAMAZEPINE, VENLAFAXINE, CLONAZEPAM, HALOPERIDOL, BUSCOPAN. Patient was hospitalized. Patient recovered.

Gefitinib Side Effects Report #4951438-5
Gefitinib side effect was reported by a Physician from UNITED KINGDOM on July 20, 2005. Male patient, weighting 133.2 lb, was diagnosed with non-small cell lung cancer, analgesic effect, depression , insomnia, pain , muscle spasms and was treated with Gefitinib. After drug was administered, patient experienced the following side effects: anaemia, diarrhoea, disease progression, intestinal obstruction, liver function test abnormal, overgrowth bacterial, pancreatic insufficiency, renal failure, somnolence. Gefitinib dosage: unknown. During the same period patient was treated with GABAPENTIN, ACETAMINOPHEN, CARBAMAZEPINE, VENLAFAXINE, CLONAZEPAM, HALOPERIDOL, BUSCOPAN. Patient was hospitalized. Patient recovered.


Gefitinib Side Effects Report #4585328-7
Gefitinib side effect was reported by a Physician from on Feb 02, 2005. Female patient, 56 years of age, weighting 171.5 lb, was diagnosed with glioma, recurrent cancer, malignant melanoma and was treated with Gefitinib. After drug was administered, patient experienced the following side effects: anaemia, blood osmolarity decreased, bone lesion, condition aggravated, dehydration, depressed level of consciousness, diabetes mellitus, diarrhoea, eating disorder . Gefitinib dosage: 500 MG QD PO. During the same period patient was treated with RAPAMUNE. Patient was hospitalized. Patient recovered.

Gefitinib Side Effects Report #4578403-4
Gefitinib side effect was reported by a Health Professional from on Feb 03, 2005. Female patient, weighting 170.9 lb, was diagnosed with glioblastoma multiforme and was treated with Gefitinib. After drug was administered, patient experienced the following side effects: anaemia, convulsion, diarrhoea, electroencephalogram abnormal, hypokalaemia, thrombocytopenia, urinary tract infection , vomiting. Gefitinib dosage: 250 MG PO, QD. During the same period patient was treated with RAPAMUNE, DEPAKOTE, DECADRON, ALBUTEROL PRN. Patient was hospitalized. Patient recovered.

Gefitinib Side Effects Report #4578488-5
Gefitinib side effect was reported by a Health Professional from on Feb 02, 2005. Female patient, weighting 171.5 lb, was diagnosed with glioblastoma multiforme and was treated with Gefitinib. After drug was administered, patient experienced the following side effects: dehydration, diarrhoea, hyperglycaemia, hyponatraemia, lethargy, leukopenia, mucosal inflammation, pneumonia , vaginal lesion. Gefitinib dosage: 500 MG PO QD. During the same period patient was treated with RAPAMUNE, DECADRON, MAGIC MOUTH WASH WITH LIDOCAINE, PEPCID, AMOXICILLIN. Patient was hospitalized. Patient recovered.

Gefitinib Side Effects Report #4798171-0
Gefitinib side effect was reported by a Health Professional from UNITED STATES on Oct 11, 2005. Female patient, weighting 213.8 lb, was diagnosed with glioblastoma multiforme and was treated with Gefitinib. After drug was administered, patient experienced the following side effects: dehydration, diarrhoea, oral intake reduced. Gefitinib dosage: 750 MG PO, QD. During the same period patient was treated with RAPAMUNE, AVALIDE, DECADRON, KEPPRA, PEPCID, LOVENOX, MAGIC MOUTHWASH, PHENERGAN. Patient was hospitalized. Patient recovered.

Gefitinib Side Effects Report #4826726-3
Gefitinib side effect was reported by a Health Professional from UNITED STATES on Nov 10, 2005. Female patient, weighting 213.8 lb, was diagnosed with glioblastoma multiforme and was treated with Gefitinib. After drug was administered, patient experienced the following side effects: asthenia, dehydration, diarrhoea, escherichia infection, nausea , oral intake reduced. Gefitinib dosage: 750 MG PO QD. During the same period patient was treated with RAPAMUNE, AVALIDE, DECADRON, KEPPRA, PEPCID, LOVONOX, MAGIC MOUTHWASH, PHENERGAN. Patient was hospitalized. Patient recovered.


Gefitinib Side Effects Report #4909126-7
Gefitinib side effect was reported by a Health Professional from UNITED STATES on Feb 10, 2006. Male patient, weighting 148.6 lb, was diagnosed with glioblastoma multiforme and was treated with Gefitinib. After drug was administered, patient experienced the following side effects: asthenia, complex partial seizures, convulsion, diarrhoea, dyskinesia, epistaxis, fall , haemoptysis. Gefitinib dosage: 1500 MG, PO, QD. During the same period patient was treated with RAPAMUNE, AVALIDE, DECADRON SRC, KEPPRA, PEPCID, LOVENOX, MAGIC MOUTHWASH, PHENERGAN. Patient was hospitalized. Patient recovered.

Gefitinib Side Effects Report #4915143-3
Gefitinib side effect was reported by a Health Professional from UNITED STATES on Feb 15, 2006. Male patient, weighting 148.6 lb, was diagnosed with glioblastoma multiforme and was treated with Gefitinib. After drug was administered, patient experienced the following side effects: asthenia, cerebrovascular accident, complex partial seizures, convulsion, diarrhoea, dyskinesia, epistaxis, fall . Gefitinib dosage: 1500 MG PO , QD. During the same period patient was treated with RAPAMUNE, AVALIDE, DECADRON SRC, KEPPRA, PEPCID, LOVENOX, MAGIC MOUTHWASH, PHENERGAN. Patient was hospitalized. Patient recovered.

Gefitinib Side Effects Report #4573971-0
Gefitinib side effect was reported by a Physician from on Jan 26, 2005. Female patient, 56 years of age, weighting 171.5 lb, was diagnosed with brain neoplasm malignant, glioma, recurrent cancer and was treated with Gefitinib. After drug was administered, patient experienced the following side effects: activities of daily living impaired, aphagia, dehydration, depressed level of consciousness, diarrhoea, hyponatraemia, lethargy, leukopenia, mucosal inflammation. Gefitinib dosage: 500 MG QD PO. During the same period patient was treated with RAPAMUNE. Patient was hospitalized. Patient recovered.