Fludarabine and transplant failure Patient Reports February 12, 2012

Fludarabine Side Effects Report #5643568-X
Fludarabine side effect was reported by a Consumer or non-health professional from NETHERLANDS on Feb 13, 2008. Female patient was diagnosed with prophylaxis against transplant rejection, prophylaxis against graft versus host disease and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: transplant failure. Fludarabine dosage: AS USED: 30 MG/M2. During the same period patient was treated with CYCLOPHOSPHAMIDE, CYCLOSPORINE, METHOTREXATE. Patient died.

Fludarabine Side Effects Report #5643569-1
Fludarabine side effect was reported by a Consumer or non-health professional from NETHERLANDS on Feb 13, 2008. Female patient was diagnosed with prophylaxis against transplant rejection, prophylaxis against graft versus host disease and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: transplant failure. Fludarabine dosage: AS USED: 30 MG/M2. During the same period patient was treated with CYCLOPHOSPHAMIDE, CYCLOSPORINE, METHOTREXATE. Patient died.

Fludarabine Side Effects Report #5116914-3
Fludarabine side effect was reported by a Health Professional from UNITED STATES on Sept 27, 2006. Male patient, 60 years of age, weighting 190.7 lb, was diagnosed with myelodysplastic syndrome and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: neutrophil count abnormal, platelet count abnormal, stem cell transplant, transplant failure. Fludarabine dosage: 71MG IV QD. During the same period patient was treated with CYTOXAN, UMBILICAL CORD BLOOD, NEUPOGEN, CYCLOSPORINE, MYCOPHENOLATE MOFETIL, ACYCLOVIR, CASPOFUNGIN. Patient was hospitalized. Patient recovered.

Fludarabine Side Effects Report #5634990-6
Fludarabine side effect was reported by a Consumer or non-health professional from UNITED STATES on Feb 07, 2008. Male patient, 17 years of age, was diagnosed with immunosuppression, prophylaxis against graft versus host disease and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: aspergillosis, multi-organ failure, transplant failure. Fludarabine dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, CYCLOSPORIN A, METHYLPREDNISOLONE. Patient died.


Fludarabine Side Effects Report #5797730-6
Fludarabine side effect was reported by a Health Professional from GERMANY on June 18, 2008. Female patient, 39 years of age, weighting 185.2 lb, was diagnosed with bone marrow conditioning regimen, antiviral prophylaxis, antifungal prophylaxis, antibiotic prophylaxis, white blood cell count decreased and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: mucosal inflammation, organising pneumonia, transplant failure. Fludarabine dosage: TOTAL DAILY DOSE: 120 MG/M2. During the same period patient was treated with ACYCLOVIR, ITRACONAZOLE, VORICONAZOLE, METRONIDAZOLE, IMMUNE GLOBULIN INTRAVENOUS, NEUPOGEN. Patient died.

Fludarabine Side Effects Report #5799732-2
Fludarabine side effect was reported by a Health Professional from GERMANY on June 18, 2008. Female patient, 39 years of age, weighting 185.2 lb, was diagnosed with bone marrow conditioning regimen, antiviral prophylaxis, antifungal prophylaxis, antibiotic prophylaxis, white blood cell count decreased and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: mucosal inflammation, organising pneumonia, transplant failure. Fludarabine dosage: TOTAL DAILY DOSE: 120 MG/M2. During the same period patient was treated with ACYCLOVIR, ITRACONAZOLE, VORICONAZOLE, METRONIDAZOLE, IMMUNE GLOBULIN INTRAVENOUS, NEUPOGEN. Patient died.

Fludarabine Side Effects Report #5595444-9
Fludarabine side effect was reported by a Health Professional from UNITED KINGDOM on Jan 08, 2008. Male patient, 32 years of age, was diagnosed with bone marrow conditioning regimen and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute myeloid leukaemia, aplastic anaemia, transplant failure. Fludarabine dosage: unknown. During the same period patient was treated with ALEMTUZUMAB, CYCLOPHOSPHAMIDE. Patient recovered.

Fludarabine Side Effects Report #5796302-7
Fludarabine side effect was reported by a Consumer or non-health professional from JAPAN on June 19, 2008. Male patient, 61 years of age, was diagnosed with acute myeloid leukaemia, prophylaxis against graft versus host disease and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: enterococcal infection, sepsis , staphylococcal bacteraemia, transplant failure. Fludarabine dosage: unknown. During the same period patient was treated with FLUDARABINE PHOSPHATE, MELPHALAN, TACROLIMUS, METHOTREXATE. Patient died.

Fludarabine Side Effects Report #5836410-5
Fludarabine side effect was reported by a Consumer or non-health professional from JAPAN on July 27, 2008. Male patient, 61 years of age, was diagnosed with acute myeloid leukaemia, prophylaxis against graft versus host disease and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: enterococcal bacteraemia, sepsis , staphylococcal bacteraemia, transplant failure. Fludarabine dosage: unknown. During the same period patient was treated with FLUDARABINE PHOSPHATE, MELPHALAN, TACROLIMUS, METHOTREXATE. Patient died.


Fludarabine Side Effects Report #5796321-0
Fludarabine side effect was reported by a Consumer or non-health professional from JAPAN on June 19, 2008. Female patient, 59 years of age, was diagnosed with acute myeloid leukaemia, prophylaxis against graft versus host disease and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: pneumonia , transplant failure. Fludarabine dosage: unknown. During the same period patient was treated with FLUDARABINE PHOSPHATE, MELPHALAN, TACROLIMUS, METHOTREXATE. Patient recovered.

Fludarabine Side Effects Report #5836408-7
Fludarabine side effect was reported by a Consumer or non-health professional from JAPAN on July 27, 2008. Female patient, 59 years of age, was diagnosed with acute myeloid leukaemia, prophylaxis against graft versus host disease and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: pneumonia , transplant failure. Fludarabine dosage: unknown. During the same period patient was treated with FLUDARABINE PHOSPHATE, MELPHALAN, TACROLIMUS, METHOTREXATE. Patient recovered.

Fludarabine Side Effects Report #5796300-3
Fludarabine side effect was reported by a Consumer or non-health professional from JAPAN on June 19, 2008. Male patient, 63 years of age, was diagnosed with prophylaxis against graft versus host disease and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: enterococcal infection, multi-organ failure, streptococcal bacteraemia, transplant failure. Fludarabine dosage: unknown. During the same period patient was treated with FLUDARABINE PHOSPHATE, MELPHALAN, TACROLIMUS, METHOTREXATE. Patient died.

Fludarabine Side Effects Report #5836409-9
Fludarabine side effect was reported by a Consumer or non-health professional from JAPAN on July 27, 2008. Male patient, 63 years of age, was diagnosed with prophylaxis against graft versus host disease and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: enterococcal bacteraemia, multi-organ failure, streptococcal bacteraemia, transplant failure. Fludarabine dosage: unknown. During the same period patient was treated with FLUDARABINE PHOSPHATE, MELPHALAN, TACROLIMUS, METHOTREXATE. Patient died.

Fludarabine Side Effects Report #6123988-X
Fludarabine side effect was reported by a Health Professional from UNITED STATES on Mar 18, 2009. Male patient, 56 years of age, weighting 273.4 lb, was treated with Fludarabine. After drug was administered, patient experienced the following side effects: human herpesvirus 6 infection, pulmonary haemorrhage, transplant failure. Fludarabine dosage: 65MG X3 DAYS IV. During the same period patient was treated with MELPHALAN. Patient died on 03/15/2009.


Fludarabine Side Effects Report #4665918-3
Fludarabine side effect was reported by a Health Professional from on May 16, 2005. Male patient, 47 years of age, weighting 166.4 lb, was diagnosed with chronic lymphocytic leukaemia, transplant and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: chills, hypoxia, lymphoproliferative disorder, pyrexia, transplant failure. Fludarabine dosage: 65 MG QD IV. During the same period patient was treated with CYTOXAN, VANBCOMYCIN, PENTAMADINE, AZTREONAM, VORICONAZOLE, ACYCLOVIR, CARAFATE. Patient was hospitalized. Patient recovered.

Fludarabine Side Effects Report #4935050-X
Fludarabine side effect was reported by a Health Professional from UNITED STATES on Mar 06, 2006. Female patient, 27 years of age, weighting 134.3 lb, was treated with Fludarabine. After drug was administered, patient experienced the following side effects: transplant failure. Fludarabine dosage: 58 MG /QD/IV. During the same period patient was treated with CYTOXAN, UMBILICAL CORD BLOOD, ATGAM. Patient was hospitalized. Patient recovered.

Fludarabine Side Effects Report #5258080-X
Fludarabine side effect was reported by a Physician from GERMANY on Feb 22, 2007. Male patient, weighting 233.7 lb, was treated with Fludarabine. After drug was administered, patient experienced the following side effects: catheter bacteraemia, herpes simplex , leukopenia, mucosal inflammation, pseudomonal sepsis, transplant failure. Fludarabine dosage: 30 MG/M2, UNK. During the same period patient was treated with CAMPATH, AMOXICILLIN, FAMVIR, SEMPERA, AMPHO, COTRIMTE, LEUCOVORIN CALCIUM. Patient was hospitalized. Patient recovered.

Fludarabine Side Effects Report #5643566-6
Fludarabine side effect was reported by a Consumer or non-health professional from NETHERLANDS on Feb 13, 2008. Female patient was diagnosed with prophylaxis against graft versus host disease and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: transplant failure. Fludarabine dosage: TOTAL DAILY DOSE: 120 MG/M2. During the same period patient was treated with CYCLOPHOPSHAMIDE, CYCLOSPORINE, METHOTREXATE. Patient died.

Fludarabine Side Effects Report #5643567-8
Fludarabine side effect was reported by a Consumer or non-health professional from NETHERLANDS on Feb 13, 2008. Female patient was diagnosed with prophylaxis against graft versus host disease and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: transplant failure. Fludarabine dosage: TOTAL DAILY DOSE: 120 MG/M2. During the same period patient was treated with CYCLOPHOPSHAMIDE, CYCLOSPORINE, METHOTREXATE. Patient died.


Fludarabine Side Effects Report #5643570-8
Fludarabine side effect was reported by a Consumer or non-health professional from NETHERLANDS on Feb 13, 2008. Female patient was diagnosed with prophylaxis against graft versus host disease and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: transplant failure. Fludarabine dosage: TOTAL DAILY DOSE: 120 MG/M2. During the same period patient was treated with CYCLOPHOPSHAMIDE, CYCLOSPORINE, METHOTREXATE. Patient died.

Fludarabine Side Effects Report #5643571-X
Fludarabine side effect was reported by a Consumer or non-health professional from NETHERLANDS on Feb 13, 2008. Female patient was diagnosed with prophylaxis against graft versus host disease and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: transplant failure. Fludarabine dosage: TOTAL DAILY DOSE: 120 MG/M2. During the same period patient was treated with CYCLOPHOPSHAMIDE, CYCLOSPORINE, METHOTREXATE. Patient died.

Fludarabine Side Effects Report #5643572-1
Fludarabine side effect was reported by a Consumer or non-health professional from NETHERLANDS on Feb 13, 2008. Female patient was diagnosed with prophylaxis against graft versus host disease and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: transplant failure. Fludarabine dosage: TOTAL DAILY DOSE: 120 MG/M2. During the same period patient was treated with CYCLOPHOPSHAMIDE, CYCLOSPORINE, METHOTREXATE. Patient died.

Fludarabine Side Effects Report #5643573-3
Fludarabine side effect was reported by a Consumer or non-health professional from NETHERLANDS on Feb 13, 2008. Female patient was diagnosed with prophylaxis against graft versus host disease and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: transplant failure. Fludarabine dosage: TOTAL DAILY DOSE: 120 MG/M2. During the same period patient was treated with CYCLOPHOPSHAMIDE, CYCLOSPORINE, METHOTREXATE. Patient died.