Fludarabine and infection Patient Reports February 12, 2012

Fludarabine Side Effects Report #5901871-X
Fludarabine side effect was reported by a Health Professional from AUSTRALIA on June 14, 2008. Female patient, 51 years of age, was diagnosed with stem cell transplant, prophylaxis against graft versus host disease, antiviral prophylaxis, antifungal prophylaxis and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: infection . Fludarabine dosage: unknown. During the same period patient was treated with MELPHALAN, CYCLOPHOSPHAMIDE, CYCLOSPORINE, METHOTREXATE, ANTIVIRAL PROPHYLAXIS, FLUCONAZOLE. Patient died.

Fludarabine Side Effects Report #5796255-1
Fludarabine side effect was reported by a Health Professional from GERMANY on June 18, 2008. Male patient, 21 years of age, was diagnosed with stem cell transplant, cytomegalovirus infection , prophylaxis and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease in skin, cytomegalovirus infection , encephalitis viral, fungal infection , herpes virus infection, human polyomavirus infection, weight decreased. Fludarabine dosage: unknown. During the same period patient was treated with FOSCARNET, CYCLOSPORINE, MOFETIL, ACYCLOVIR. Patient was hospitalized. Patient died.

Fludarabine Side Effects Report #5797729-X
Fludarabine side effect was reported by a Health Professional from GERMANY on June 18, 2008. Male patient, 21 years of age, was diagnosed with stem cell transplant, cytomegalovirus infection , prophylaxis and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease in skin, cytomegalovirus infection , encephalitis viral, fungal infection , herpes virus infection, human polyomavirus infection, weight decreased. Fludarabine dosage: unknown. During the same period patient was treated with FOSCARNET, CYCLOSPORINE, MOFETIL, ACYCLOVIR. Patient was hospitalized. Patient died.

Fludarabine Side Effects Report #5690163-2
Fludarabine side effect was reported by a Consumer or non-health professional from GERMANY on Mar 07, 2008. Female patient was diagnosed with stem cell transplant and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: chronic graft versus host disease, diarrhoea, haemolytic uraemic syndrome, infection , mucosal inflammation, nausea , neutropenia, thrombotic thrombocytopenic purpura. Fludarabine dosage: AS USED: 30 MG/M2. During the same period patient was treated with CYTARABINE, AMSACRINE, THYMOGLOBULIN. Patient was hospitalized. Patient died.


Fludarabine Side Effects Report #4901402-7
Fludarabine side effect was reported by a Health Professional from UNITED STATES on Feb 02, 2006. Female patient was diagnosed with stem cell transplant and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: asthenia, blood culture positive, depressed level of consciousness, dyspnoea, exophthalmos, headache , infection , metastases to central nervous system. Fludarabine dosage: 52 MG ONCE DAY IV DRIP. During the same period patient was treated with CAMPATH, BUSULFAN. Patient died on 02/01/2006.

Fludarabine Side Effects Report #5693431-3
Fludarabine side effect was reported by a Physician from UNITED STATES on Mar 07, 2008. Female patient was diagnosed with myelodysplastic syndrome, prophylaxis against graft versus host disease and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease, chronic graft versus host disease, infection . Fludarabine dosage: TOTAL DAILY DOSE: 25 MG/M2 UNIT DOSE: 25 MG/M2. During the same period patient was treated with BUSULFAN, MELPHALAN, ANTITHYMOCYTE IMMUNOGLOBULIN. Patient died.

Fludarabine Side Effects Report #5143410-X
Fludarabine side effect was reported by a Health Professional from UNITED STATES on Nov 01, 2006. Male patient, weighting 163.4 lb, was diagnosed with lymphoma  and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: aspiration, blood culture positive, heart rate increased, infection , pharyngolaryngeal pain, productive cough, respiratory rate increased, sputum discoloured, staphylococcal infection . Fludarabine dosage: 57 MG DAILY IV. During the same period patient was treated with MELPHAAN, CAMPATH. Patient was hospitalized. Patient recovered.

Fludarabine Side Effects Report #5126888-7
Fludarabine side effect was reported by a Health Professional from UNITED STATES on Oct 11, 2006. Male patient, weighting 286.6 lb, was diagnosed with leukaemia and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: chills, clostridial infection, diarrhoea, eosinophilia, graft versus host disease, nausea , pyrexia, rash . Fludarabine dosage: 72MG DAILY IV. During the same period patient was treated with MELPHALAN, CAMPATH, PREVACID, DIFLUCAN, VALTREX, PROGRAF, PRINIVOL, BACTIRM. Patient was hospitalized. Patient recovered.

Fludarabine Side Effects Report #5690052-3
Fludarabine side effect was reported by a Consumer or non-health professional from UNITED STATES on Mar 07, 2008. Female patient was diagnosed with haematological malignancy and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease, chronic graft versus host disease, infection , multi-organ failure, respiratory failure. Fludarabine dosage: TOTAL DAILY DOSE: 160 MG/M2 UNIT DOSE: 160 MG/M2. During the same period patient was treated with MELPHALAN, THIOTEPA, THYMOGLOBULIN. Patient died.


Fludarabine Side Effects Report #5720946-1
Fludarabine side effect was reported by a Health Professional from UNITED STATES on Apr 25, 2008. Male patient was diagnosed with chronic myeloid leukaemia and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: cystitis haemorrhagic, cytomegalovirus viraemia, encephalopathy, headache , hydronephrosis, infection , mental status changes, renal failure acute. Fludarabine dosage: 51 MG DAILY IV DRIP. During the same period patient was treated with THIOTEPA, RABBIT ATG. Patient was hospitalized. Patient recovered.

Fludarabine Side Effects Report #5775349-0
Fludarabine side effect was reported by a Health Professional from UNITED STATES on June 16, 2008. Male patient was diagnosed with chronic myeloid leukaemia and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: aspiration, computerised tomogram abnormal, convulsion, infection , respiratory distress, unresponsive to stimuli. Fludarabine dosage: 51 MG DAILY IV DRIP. During the same period patient was treated with THIOTEPA, RABBIT ATG. Patient recovered.

Fludarabine Side Effects Report #4974965-3
Fludarabine side effect was reported by a Consumer or non-health professional from UNITED STATES on Apr 14, 2006. Female patient, weighting 163.1 lb, was diagnosed with chronic lymphocytic leukaemia and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: brain oedema, cerebral toxoplasmosis, cerebrovascular accident, hemiparesis, infection , neutropenia. Fludarabine dosage: 220 MG. During the same period patient was treated with RITUXIMAB. Patient was hospitalized. Patient recovered.

Fludarabine Side Effects Report #5819364-7
Fludarabine side effect was reported by a Health Professional from FRANCE on July 11, 2008. Male patient, 49 years of age, was diagnosed with bone marrow conditioning regimen, prophylaxis against graft versus host disease and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease, infection . Fludarabine dosage: unknown. Patient died.

Fludarabine Side Effects Report #5247416-1
Fludarabine side effect was reported by a Health Professional from UNITED STATES on Feb 23, 2007. Female patient, weighting 190.5 lb, was diagnosed with bone marrow conditioning regimen and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: cerebrovascular accident, hypoventilation, infection , interstitial lung disease, multi-organ failure, pleural effusion, pneumonia , post procedural complication, pulmonary oedema. Fludarabine dosage: 60 MG DAILY IV DRIP. During the same period patient was treated with CAMPATH, MELPHALAN. Patient died.


Fludarabine Side Effects Report #5618230-X
Fludarabine side effect was reported by a Health Professional from UNITED STATES on Feb 06, 2008. Female patient was diagnosed with bone marrow conditioning regimen and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: blood pressure decreased, hypoxia, infection , lung disorder, respiratory distress. Fludarabine dosage: 50 MG DAILY IV DRIP. During the same period patient was treated with THIOTEPA. Patient was hospitalized. Patient recovered.

Fludarabine Side Effects Report #4999624-2
Fludarabine side effect was reported by a Health Professional from UNITED STATES on May 09, 2006. Male patient was diagnosed with b precursor type acute leukaemia and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: body temperature increased, chills, dyspnoea, headache , infection . Fludarabine dosage: 56 MG (25 MG/M2) DAILY X 5 DAYS IV. During the same period patient was treated with RITUXAN. Patient was hospitalized. Patient recovered.

Fludarabine Side Effects Report #4690125-8
Fludarabine side effect was reported by a Physician from on May 31, 2005. Male patient, 50 years of age, weighting 152.1 lb, was diagnosed with acute myeloid leukaemia, acute leukaemia, lower respiratory tract infection and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute myeloid leukaemia, areflexia, asthenia, cardiac tamponade, endocarditis , infection , lower respiratory tract infection, neuropathy peripheral, parainfluenzae virus infection. Fludarabine dosage: unknown. During the same period patient was treated with FLUDARABINE PHOSPHATE, CYTARABINE, VORICONAZOLE, AMBISOME, ACYCLOVIR, COTRIM, RIBAVIRIN, CIPROFLOXACIN. Patient died on 01/18/2003.

Fludarabine Side Effects Report #4818201-7
Fludarabine side effect was reported by a Health Professional from UNITED STATES on Nov 01, 2005. Male patient, 27 years of age, weighting 157.9 lb, was diagnosed with acute myeloid leukaemia, stem cell transplant and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, complications of transplant surgery, haemoptysis, infection , pleuritic pain, respiratory failure, stem cell transplant, surgical procedure repeated. Fludarabine dosage: 65MG QD IV. During the same period patient was treated with CYTOXAN. Patient was hospitalized. Patient died on 10/30/2005.

Fludarabine Side Effects Report #5321328-7
Fludarabine side effect was reported by a Health Professional from UNITED STATES on May 07, 2007. Female patient was diagnosed with acute myeloid leukaemia and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: anorexia, diarrhoea, graft versus host disease, infection , multi-organ failure, nausea , pneumatosis, portal venous gas, small intestinal obstruction. Fludarabine dosage: 60 MG DAILY IV DRIP. During the same period patient was treated with MELPHALAN, CAMPATH. Patient died on 05/01/2007.


Fludarabine Side Effects Report #6024675-9
Fludarabine side effect was reported by a Health Professional from UNITED STATES on Dec 30, 2008. Male patient, weighting 176.4 lb, was diagnosed with acute myeloid leukaemia and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: cardiac arrest , convulsion, dialysis , infection , renal impairment. Fludarabine dosage: 60MG DAILY IV. During the same period patient was treated with THIOTEPA, ANTITHMOCYTE GLOBULIN, TOTAL BODY IRRADIATION. Patient recovered.

Fludarabine Side Effects Report #5126887-5
Fludarabine side effect was reported by a Health Professional from UNITED STATES on Oct 11, 2006. Male patient, weighting 160.9 lb, was diagnosed with acute lymphocytic leukaemia and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: back pain , blood culture positive, constipation , hepatic enzyme increased, infection , intervertebral discitis, osteomyelitis. Fludarabine dosage: 57MG DAILY IV. During the same period patient was treated with MELPHALAN, CAMPATH, PROGRAF, VALTREX, DILAUDID. Patient was hospitalized. Patient recovered.

Fludarabine Side Effects Report #4839165-6
Fludarabine side effect was reported by a Consumer or non-health professional from JAPAN on Sept 14, 2005. Male patient, 67 years of age, was treated with Fludarabine. After drug was administered, patient experienced the following side effects: blood bilirubin increased, blood creatinine increased, haemodialysis, infection , pneumocystis jiroveci pneumonia, renal failure acute, thrombotic microangiopathy. Fludarabine dosage: unknown. During the same period patient was treated with MELPHALAN, NEUPOGEN, SANDIMMUNE, IRRADIATION. Patient died.

Fludarabine Side Effects Report #5883642-6
Fludarabine side effect was reported by a Consumer or non-health professional from UNITED STATES on Sept 04, 2008. Male patient, 44 years of age, weighting 180.8 lb, was diagnosed with acute lymphocytic leukaemia, prophylaxis against graft versus host disease, antibiotic prophylaxis and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, infection . Fludarabine dosage: unknown. During the same period patient was treated with MELPHALAN, THIOTEPA, RABBIT ANTI, RABBIT ANTI, TACROLIMUS, METHOTREXATE, NEUPOGEN, ANTIBIOTICS. Patient died.