Fludarabine and graft versus host disease 
Fludarabine and graft versus host disease Patient Reports February 12, 2012
Fludarabine Side Effects Report #4624009-8
Fludarabine side effect was reported by a Health Professional from on Mar 16, 2005. Female patient, 45 years of age, was diagnosed with stem cell transplant and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: aspergillosis, cytomegalovirus infection
, gastroenteritis adenovirus, graft versus host disease, liver disorder, thrombotic microangiopathy, viral diarrhoea. Fludarabine dosage: 90 MG/M2 INTRAVENOUS. During the same period patient was treated with CYCLOSPORINE, MYCOPHENOLATE MOFETIL. Patient died on 01/01/2003.Fludarabine Side Effects Report #5311847-1
Fludarabine side effect was reported by a Health Professional from UNITED STATES on Apr 27, 2007. Male patient was diagnosed with stem cell transplant and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: ascites, gallbladder disorder, graft versus host disease, hepatic lesion, hepatomegaly, liver function test abnormal, lymphadenopathy, pelvic fluid collection, retroperitoneal lymphadenopathy. Fludarabine dosage: 55 MG ONCE A DAY IV DRIP. During the same period patient was treated with CAMPATH, BUSULFAN. Patient was hospitalized. Patient recovered.
Fludarabine Side Effects Report #4680799-X
Fludarabine side effect was reported by a Health Professional from on June 01, 2005. Male patient was diagnosed with stem cell transplant and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: bacterial infection
, bronchoalveolar lavage abnormal, computerised tomogram abnormal, condition aggravated, graft versus host disease, influenza, pneumonia fungal. Fludarabine dosage: 60MG QD IV. During the same period patient was treated with MELPHALAN, CAMPATH, AVELOX, SYNTHROID, POTASSIUM CHLORIDE, AMBISON, CIDOFAVIR. Patient was hospitalized. Patient recovered.Fludarabine Side Effects Report #5032368-X
Fludarabine side effect was reported by a Health Professional from UNITED STATES on June 21, 2006. Male patient, weighting 125.0 lb, was diagnosed with stem cell transplant and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: ascites, diarrhoea, graft versus host disease, hypotension, nausea
, pyrexia. Fludarabine dosage: 48 MG DAILY IV DRIP. During the same period patient was treated with CAMPATH, MELPHALAN, METHYLPREDNISOLONE, PROGRAF, ACTIGALL, SPIRONOLACTONE, VANCOMYCIN, GANCICLOVIR. Patient died on 06/20/1946.Fludarabine Side Effects Report #5483742-9
Fludarabine side effect was reported by a Consumer or non-health professional from UNITED STATES on Oct 09, 2007. Male patient, weighting 150.1 lb, was diagnosed with myeloproliferative disorder and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease in intestine, complications of transplant surgery, myeloproliferative disorder, neoplasm recurrence, stem cell transplant. Fludarabine dosage: 70 MG DAILY FOR 5 DAYS IV. During the same period patient was treated with CYCLOPHOSPHAMIDE, MYCOFUNGIN, ZOSYN, VANCOMYCIN, URSODIAL, DESONIDE CREAM, BUDESONIDE, METHOXALON. Patient died on 10/06/2007.
Fludarabine Side Effects Report #5693431-3
Fludarabine side effect was reported by a Physician from UNITED STATES on Mar 07, 2008. Female patient was diagnosed with myelodysplastic syndrome, prophylaxis against graft versus host disease and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease, chronic graft versus host disease, infection
. Fludarabine dosage: TOTAL DAILY DOSE: 25 MG/M2 UNIT DOSE: 25 MG/M2. During the same period patient was treated with BUSULFAN, MELPHALAN, ANTITHYMOCYTE IMMUNOGLOBULIN. Patient died.Fludarabine Side Effects Report #5126888-7
Fludarabine side effect was reported by a Health Professional from UNITED STATES on Oct 11, 2006. Male patient, weighting 286.6 lb, was diagnosed with leukaemia and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: chills, clostridial infection, diarrhoea, eosinophilia, graft versus host disease, nausea
, pyrexia, rash . Fludarabine dosage: 72MG DAILY IV. During the same period patient was treated with MELPHALAN, CAMPATH, PREVACID, DIFLUCAN, VALTREX, PROGRAF, PRINIVOL, BACTIRM. Patient was hospitalized. Patient recovered.Fludarabine Side Effects Report #4715630-7
Fludarabine side effect was reported by a Health Professional from UNITED STATES on July 15, 2005. Male patient, weighting 167.6 lb, was diagnosed with chronic myeloid leukaemia and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: graft versus host disease, liver function test abnormal, oral intake reduced, renal failure acute. Fludarabine dosage: 48 MG QD X5D IV. During the same period patient was treated with BUSULFAN, PROGRAF, PREVACID, HYDROCHLOROTHIAZIDE, VORICONAZOLE, BACTRIM, VALTREX. Patient was hospitalized. Patient recovered.
Fludarabine Side Effects Report #4624413-8
Fludarabine side effect was reported by a Health Professional from on Mar 30, 2005. Female patient, 47 years of age, weighting 189.2 lb, was diagnosed with chronic lymphocytic leukaemia and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: blood bilirubin abnormal, eye disorder, fatigue, graft versus host disease, hypoxia, pleural effusion, pneumonia
, pyrexia, skin disorder. Fludarabine dosage: 85MG QD INTRAVENOU. During the same period patient was treated with CYTOXAN, ACYCLOVIR, CIPROFLOXACIN, VANCOMYCIN, ABELCET, HYDROCORTISONE, GLUTAMINE, CAROFATE. Patient was hospitalized. Patient recovered.Fludarabine Side Effects Report #5811439-1
Fludarabine side effect was reported by a Health Professional from FRANCE on July 02, 2008. Female patient, 64 years of age, was diagnosed with bone marrow conditioning regimen, prophylaxis against graft versus host disease, antiviral prophylaxis and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: cytomegalovirus colitis, cytomegalovirus infection
, graft versus host disease, hyperthermia, pneumonia cytomegaloviral, pulmonary embolism , pulmonary mass, thrombosis. Fludarabine dosage: unknown. During the same period patient was treated with THYMOGLOBULIN, CYCLOSPORINE, MYCOPHENOLATE MOFETIL, VALACYCLOVIR. Patient recovered.Fludarabine Side Effects Report #5866869-9
Fludarabine side effect was reported by a Health Professional from AUSTRIA on Aug 20, 2008. Female patient, child 11 years of age, was diagnosed with bone marrow conditioning regimen, prophylaxis against graft versus host disease, acute graft versus host disease and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: bronchopulmonary aspergillosis, condition aggravated, epstein-barr virus infection, graft versus host disease, human herpesvirus 6 infection. Fludarabine dosage: unknown. During the same period patient was treated with ALEMTUZUMAB, MELPHALAN, CYCLOSPORINE, PREDNISOLONE, MYCOPHENOLATE MOFETIL, DEXAMETHASONE. Patient recovered.
Fludarabine Side Effects Report #5069810-4
Fludarabine side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on July 13, 2006. Female patient, 16 years of age, was diagnosed with aplastic anaemia and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease in skin, anaemia haemolytic autoimmune, aplastic anaemia, bone marrow disorder, disease recurrence, pancytopenia, renal failure, viral infection
. Fludarabine dosage: unknown. During the same period patient was treated with CAMPATH, CYCLOPHOSPHAMIDE, CYCLOSPORINE, CORTICOSTEROIDS. Patient recovered.Fludarabine Side Effects Report #5321328-7
Fludarabine side effect was reported by a Health Professional from UNITED STATES on May 07, 2007. Female patient was diagnosed with acute myeloid leukaemia and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: anorexia, diarrhoea, graft versus host disease, infection
, multi-organ failure, nausea , pneumatosis, portal venous gas, small intestinal obstruction. Fludarabine dosage: 60 MG DAILY IV DRIP. During the same period patient was treated with MELPHALAN, CAMPATH. Patient died on 05/01/2007.Fludarabine Side Effects Report #6120572-9
Fludarabine side effect was reported by a Health Professional from UNITED STATES on Mar 12, 2009. Male patient, weighting 167.1 lb, was diagnosed with acute myeloid leukaemia and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease in intestine, acute myeloid leukaemia, cough, hyperhidrosis, influenza, nasal congestion, nausea
. Fludarabine dosage: 72 MG DAILY X 5 IV. During the same period patient was treated with CYCLOPHOSPHAMIDE. Patient was hospitalized. Patient recovered.Fludarabine Side Effects Report #4818921-4
Fludarabine side effect was reported by a Consumer or non-health professional from UNITED STATES on Nov 02, 2005. Male patient, weighting 162.7 lb, was diagnosed with acute myeloid leukaemia and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: aphasia
, aspergillosis, brain scan abnormal, graft versus host disease, graft versus host disease in liver, graft versus host disease in skin, mental status changes, nervous system disorder, nuclear magnetic resonance imaging abnormal. Fludarabine dosage: unknown. During the same period patient was treated with BUSULFAN. Patient was hospitalized. Patient died.Fludarabine Side Effects Report #5110893-0
Fludarabine side effect was reported by a Health Professional from GERMANY on Sept 08, 2006. Female patient, 59 years of age, was treated with Fludarabine. After drug was administered, patient experienced the following side effects: catheter related infection, fall
, graft versus host disease, proteus infection, retroperitoneal haematoma, syncope vasovagal, thrombosis. Fludarabine dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE. Patient was hospitalized. Patient recovered.Fludarabine Side Effects Report #5022538-9
Fludarabine side effect was reported by a Health Professional from GERMANY on May 18, 2006. Female patient, 59 years of age, was treated with Fludarabine. After drug was administered, patient experienced the following side effects: catheter related infection, disease recurrence, fall
, graft versus host disease, proteus infection, retroperitoneal haematoma, shock, syncope vasovagal, venous thrombosis limb. Fludarabine dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE. Patient was hospitalized. Patient recovered.Fludarabine Side Effects Report #5763929-8
Fludarabine side effect was reported by a Health Professional from UNITED STATES on June 06, 2008. Male patient, 58 years of age, weighting 177.3 lb, was treated with Fludarabine. After drug was administered, patient experienced the following side effects: arrhythmia
, atrial flutter, diarrhoea, graft versus host disease, pyrexia. Fludarabine dosage: 60 MG DAILY IV/OVER 30 MINS. During the same period patient was treated with MELPHALAN. Patient was hospitalized. Patient recovered.Fludarabine Side Effects Report #5657924-7
Fludarabine side effect was reported by a Consumer or non-health professional from JAPAN on Mar 06, 2008. Male patient, 56 years of age, was diagnosed with bone marrow transplant
and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: blood stem cell transplant failure, bone marrow failure, convulsion, csf virus identified, encephalitis herpes, engraftment syndrome, graft versus host disease, human herpesvirus 6 infection, memory impairment. Fludarabine dosage: 120 MG/M2. During the same period patient was treated with IRRADIATION, METHOTREXATE, ENDOXAN, FLUOROURACIL, CICLOSPORIN, NEUPOGEN. Patient died.Fludarabine Side Effects Report #5661536-9
Fludarabine side effect was reported by a Consumer or non-health professional from JAPAN on Mar 05, 2008. Male patient, 56 years of age, was diagnosed with bone marrow transplant
and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: blood stem cell transplant failure, bone marrow failure, convulsion, csf virus identified, encephalitis herpes, engraftment syndrome, graft versus host disease, human herpesvirus 6 infection, memory impairment. Fludarabine dosage: 120 MG/M2. During the same period patient was treated with IRRADIATION, METHOTREXATE, ENDOXAN, FLUOROURACIL, NEORAL, NEUPOGEN, SANDIMMUNE. Patient died.Fludarabine Side Effects Report #4886234-0
Fludarabine side effect was reported by a Physician from UNITED STATES on Jan 10, 2006. Male patient, 47 years of age, was diagnosed with bone marrow transplant
and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: autoantibody positive, autoimmune hepatitis, gamma-glutamyltransferase increased, graft versus host disease, oral mucosal disorder, transaminases increased. Fludarabine dosage: 50MG/M2. During the same period patient was treated with CYCLOPHOSPHAMIDE, METHOTREXATE, CYCLOSPORINE. Patient recovered.Fludarabine Side Effects Report #4762818-5
Fludarabine side effect was reported by a Physician from INDIA on Aug 31, 2005. Male patient, 42 years of age, was diagnosed with graft versus host disease and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: chest x-ray abnormal, graft versus host disease, pneumonia fungal, respiratory failure, tachypnoea. Fludarabine dosage: unknown. During the same period patient was treated with ANTITHYMOCYTE IMMUNOGLOBULIN, BUSULFAN, METHOTREXATE, MYCOPHENOLATE MOFETIL, SIROLIMUS, GANCICLOVIR, CORTICOSTEROIDS, CYCLOSPORINE. Patient died.
Fludarabine Side Effects Report #4712144-5
Fludarabine side effect was reported by a Consumer or non-health professional from JAPAN on July 06, 2005. Male patient, 14 years of age, was diagnosed with stem cell transplant and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: cough, dermatitis bullous, dermatitis exfoliative, graft versus host disease, malignant neoplasm progression, metastases to lung, pleural disorder
. Fludarabine dosage: 30 MG/M2, QD. During the same period patient was treated with BUSULFAN, CYCLOSPORINE. Patient died.Fludarabine Side Effects Report #4763621-2
Fludarabine side effect was reported by a Consumer or non-health professional from JAPAN on July 06, 2005. Male patient, 14 years of age, was diagnosed with stem cell transplant and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: blister, cough, dermatitis exfoliative, graft versus host disease, malignant neoplasm progression, metastases to lung, pleural disorder
, skin exfoliation. Fludarabine dosage: 30 MG/M2, QD. During the same period patient was treated with BUSULFAN, SANDIMMUNE. Patient died.Fludarabine Side Effects Report #5965820-0
Fludarabine side effect was reported by a Health Professional from UNITED STATES on Nov 21, 2008. Male patient, weighting 165.3 lb, was treated with Fludarabine. After drug was administered, patient experienced the following side effects: diarrhoea, graft versus host disease, hypotension, lethargy, nausea
, tonic clonic movements. Fludarabine dosage: unknown. During the same period patient was treated with MELPHALAN, SEE ATTACHMENT. Patient was hospitalized. Patient died on 11/07/2008.