Fludarabine and cytomegalovirus infection Patient Reports February 12, 2012

Fludarabine Side Effects Report #4623493-3
Fludarabine side effect was reported by a Consumer or non-health professional from on Mar 16, 2005. Female patient, 57 years of age, was diagnosed with stem cell transplant and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: blood disorder, cytomegalovirus infection , rotavirus test positive, thrombotic microangiopathy, viral diarrhoea. Fludarabine dosage: 90 MG/M2, INTRAVENOUS. During the same period patient was treated with THALIDOMIDE, CYCLOPHOSPHAMIDE, ETOPOSIDE, DEXAMETHASONE, MELPHALAN, CYCLOSPORINE, MYCOPHENOLATE MOFETIL. Patient recovered.

Fludarabine Side Effects Report #5811440-8
Fludarabine side effect was reported by a Health Professional from PORTUGAL on July 02, 2008. Male patient, 53 years of age, was diagnosed with stem cell transplant, graft versus host disease and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease, anaemia, cytomegalovirus infection , glomerulonephritis minimal lesion, lichenoid keratosis, meningioma, nephrotic syndrome, poikiloderma, rash maculo-papular. Fludarabine dosage: unknown. During the same period patient was treated with BUSULFAN, CYCLOSPORINE, ENALAPRIL MALEATE, BISOPROLOL FUMARATE, SULFAMETHOXAZOLE AND TRIMETHOPRIM, ACYCLOVIR, MIANSERINE, FOLATE. Patient recovered.

Fludarabine Side Effects Report #4624009-8
Fludarabine side effect was reported by a Health Professional from on Mar 16, 2005. Female patient, 45 years of age, was diagnosed with stem cell transplant and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: aspergillosis, cytomegalovirus infection , gastroenteritis adenovirus, graft versus host disease, liver disorder, thrombotic microangiopathy, viral diarrhoea. Fludarabine dosage: 90 MG/M2 INTRAVENOUS. During the same period patient was treated with CYCLOSPORINE, MYCOPHENOLATE MOFETIL. Patient died on 01/01/2003.

Fludarabine Side Effects Report #5901852-6
Fludarabine side effect was reported by a Health Professional from GERMANY on June 14, 2008. Male patient, 30 years of age, was diagnosed with stem cell transplant, aplastic anaemia, antibiotic prophylaxis, antifungal prophylaxis and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: cytomegalovirus infection . Fludarabine dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, ATGAM, CYCLOSPORINE, STEROIDS, FLUORCHINOLONE PROPHYLAXIS, PENTAMIDINE, TRIMETHOPRIM. Patient recovered.


Fludarabine Side Effects Report #5796255-1
Fludarabine side effect was reported by a Health Professional from GERMANY on June 18, 2008. Male patient, 21 years of age, was diagnosed with stem cell transplant, cytomegalovirus infection , prophylaxis and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease in skin, cytomegalovirus infection , encephalitis viral, fungal infection , herpes virus infection, human polyomavirus infection, weight decreased. Fludarabine dosage: unknown. During the same period patient was treated with FOSCARNET, CYCLOSPORINE, MOFETIL, ACYCLOVIR. Patient was hospitalized. Patient died.

Fludarabine Side Effects Report #5797729-X
Fludarabine side effect was reported by a Health Professional from GERMANY on June 18, 2008. Male patient, 21 years of age, was diagnosed with stem cell transplant, cytomegalovirus infection , prophylaxis and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease in skin, cytomegalovirus infection , encephalitis viral, fungal infection , herpes virus infection, human polyomavirus infection, weight decreased. Fludarabine dosage: unknown. During the same period patient was treated with FOSCARNET, CYCLOSPORINE, MOFETIL, ACYCLOVIR. Patient was hospitalized. Patient died.

Fludarabine Side Effects Report #4665682-8
Fludarabine side effect was reported by a Consumer or non-health professional from on May 17, 2005. Male patient, weighting 164.2 lb, was diagnosed with non-hodgkin's lymphoma and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: cytomegalovirus infection , diarrhoea, failure to thrive, renal failure. Fludarabine dosage: 60 MG IV QD X 5 DOSES. During the same period patient was treated with BUSULFAN. Patient recovered.

Fludarabine Side Effects Report #5565427-3
Fludarabine side effect was reported by a Consumer or non-health professional from GERMANY on Dec 05, 2007. Female patient, 67 years of age, was diagnosed with multiple myeloma  and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: cytomegalovirus infection , epstein-barr virus infection, myelitis. Fludarabine dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, ANTITHYMOCYTE IMMUNOGLOBULIN, ANTITHYMOCYTE IMMUNOGLOBULIN. Patient died.

Fludarabine Side Effects Report #5801572-2
Fludarabine side effect was reported by a Health Professional from UNITED STATES on July 03, 2008. Male patient, weighting 132.3 lb, was diagnosed with chronic myeloid leukaemia and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: cerebral disorder, complications of transplant surgery, convulsion, cystitis haemorrhagic, cytomegalovirus infection , mental status changes, nuclear magnetic resonance imaging brain abnormal, renal failure. Fludarabine dosage: 30MG/M2 DAILY IV DRIP. During the same period patient was treated with THIOTEPA, THYMOGLOBULIN, TOTAL BODY IRRADIATION. Patient died on 06/22/2008.


Fludarabine Side Effects Report #5741574-8
Fludarabine side effect was reported by a Consumer or non-health professional from UNITED STATES on Mar 18, 2008. Female patient was diagnosed with chronic lymphocytic leukaemia, b-cell small lymphocytic lymphoma, prophylaxis and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: anaemia, anorexia, asthenia, cytokine release syndrome, cytomegalovirus infection , dehydration, diarrhoea, fatigue. Fludarabine dosage: TOTAL DAILY DOSE: 25 MG/M2 UNIT DOSE: 25 MG/M2. During the same period patient was treated with ALEMTUZUMAB, RITUXIMAB, ALLOPURINOL, DIPHENHYDRAMINE. Patient died.

Fludarabine Side Effects Report #5811439-1
Fludarabine side effect was reported by a Health Professional from FRANCE on July 02, 2008. Female patient, 64 years of age, was diagnosed with bone marrow conditioning regimen, prophylaxis against graft versus host disease, antiviral prophylaxis and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: cytomegalovirus colitis, cytomegalovirus infection , graft versus host disease, hyperthermia, pneumonia cytomegaloviral, pulmonary embolism , pulmonary mass, thrombosis. Fludarabine dosage: unknown. During the same period patient was treated with THYMOGLOBULIN, CYCLOSPORINE, MYCOPHENOLATE MOFETIL, VALACYCLOVIR. Patient recovered.

Fludarabine Side Effects Report #5524696-6
Fludarabine side effect was reported by a Physician from SWITZERLAND on Nov 19, 2007. Male patient, 28 years of age, was diagnosed with bone marrow conditioning regimen and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease in intestine, acute graft versus host disease in skin, arthritis bacterial, bone marrow failure, bronchopulmonary aspergillosis, chronic graft versus host disease, cytomegalovirus infection , hypogammaglobulinaemia, pneumonitis. Fludarabine dosage: unknown. During the same period patient was treated with METHOTREXATE, CYCLOSPORINE, PREDNISONE, RITUXIMAB, ETOPOSIDE, CARMUSTINE, CYTARABINE. Patient recovered.

Fludarabine Side Effects Report #5901851-4
Fludarabine side effect was reported by a Health Professional from POLAND on May 19, 2008. Female patient, 17 years of age, was diagnosed with bone marrow conditioning regimen, prophylaxis against graft versus host disease and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: cytomegalovirus infection , neurotoxicity. Fludarabine dosage: unknown. During the same period patient was treated with CYCLOSPORINE, ANTITHYMOCITE GLOBULINE, METHOTREXATE. Patient died.

Fludarabine Side Effects Report #6093378-7
Fludarabine side effect was reported by a Health Professional from ITALY on Feb 10, 2009. Male patient, 63 years of age, was treated with Fludarabine. After drug was administered, patient experienced the following side effects: anaemia haemolytic autoimmune, chronic lymphocytic leukaemia, cognitive disorder, condition aggravated, cytomegalovirus infection , diplopia, dyspnoea, hemiparesis. Fludarabine dosage: unknown. During the same period patient was treated with VINCRISTINE, PREDNISONE, CHLORAMBUCIL, RITUXIMAB, CYCLOPHOSPHAMIDE. Patient was hospitalized. Patient died.


Fludarabine Side Effects Report #4624042-6
Fludarabine side effect was reported by a Consumer or non-health professional from on Mar 16, 2005. Female patient, 40 years of age, was treated with Fludarabine. After drug was administered, patient experienced the following side effects: complications of bone marrow transplant, cytomegalovirus infection , pyrexia, stem cell transplant, surgical procedure repeated, thrombotic microangiopathy, viral diarrhoea. Fludarabine dosage: 90 MG/M2, UNK, INTRAVENOUS. During the same period patient was treated with MELPHALAN, THALIDOMIDE, CYCLOPHOSPHAMIDE, ETOPOSIDE, DEXAMETHASONE, CYCLOSPORINE, MYOCOPHENOLATE MOFETIL. Patient died on 01/01/2003.

Fludarabine Side Effects Report #5850831-6
Fludarabine side effect was reported by a Consumer or non-health professional from JAPAN on Aug 02, 2008. Female patient was diagnosed with antibiotic prophylaxis, prophylaxis against graft versus host disease, antiviral prophylaxis and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease, chronic graft versus host disease, cytomegalovirus infection , diarrhoea, encephalitis herpes, hepatotoxicity, interstitial lung disease, multi-organ failure, pneumonia . Fludarabine dosage: TOTAL DAILY DOSE: 150 MG/M2. During the same period patient was treated with NEUPOGEN, CIPROFLOXACIN, CYCLOSPORINE, TACROLIMUS, METHOTREXATE, ACYCLOVIR. Patient died.

Fludarabine Side Effects Report #5852769-7
Fludarabine side effect was reported by a Consumer or non-health professional from JAPAN on Aug 02, 2008. Female patient was diagnosed with antibiotic prophylaxis, prophylaxis against graft versus host disease, antiviral prophylaxis and was treated with Fludarabine. After drug was administered, patient experienced the following side effects: acute graft versus host disease, chronic graft versus host disease, cytomegalovirus infection , diarrhoea, encephalitis herpes, hepatotoxicity, interstitial lung disease, multi-organ failure, pneumonia . Fludarabine dosage: TOTAL DAILY DOSE: 150 MG/M2. During the same period patient was treated with NEUPOGEN, CIPROFLOXACIN, CYCLOSPORINE, TACROLIMUS, METHOTREXATE, ACYCLOVIR. Patient died.